Program - Society of Toxicology

50 th Anniversary Annual Meeting and ToxExpo
Program Description (Continued)
MONday
Abstract # Abstract #
#364 Poster Board Number.....................................721
ROLE OF THE ARYL HYDROCARBON
RECEPTOR IN INFLAMMATORY BOWEL
DISEASES. ​H. Swanson 1 , V. Arsenescu 2 , E. Choi 1 ,
R. Dingle 1 and R. Arsenescu 3 . 1 Department of
Molecular and Biomedical Pharmacology, University
of Kentucky, Lexington, KY, 2 Graduate Center
for Nutritional Sciences, University of Kentucky,
Lexington, KY and 3 Digestive Diseases and
Nutrition, University of Kentucky, Lexington, KY.
#365 Poster Board Number.....................................722
MULTIPLE INTRACELLULAR SIGNAL
MODULATORS AS EFFECTORS OF HUMAN
CONSTITUTIVE ANDROSTANE RECEPTOR
ACTIVATION. ​T. Chen, E. M. Laurenzana and
C. J. Omiecinski. Center for Molecular Toxicology,
Penn State University, University Park, PA.
#366 Poster Board Number.....................................723
CONSTRUCTING A PPARα-MEDIATED
TRANSCRIPTIONAL NETWORK
IN PRIMARY HUMAN AND RAT
HEPATOCYTES. ​C. G. Woods 1 , K. M.
Yarborough 1 , L. J. Pluta 1 , J. Pi 2 , R. S. Thomas 1
and M. E. Andersen 1 . 1 Computational Biology, The
Hamner Institutes for Health Sciences, Research
Triangle Park, NC and 2 Translational Biology, The
Hamner Institutes for Health Sciences, Research
Triangle Park, NC.
#367 Poster Board Number.....................................724
MODE OF ACTION (MOA) AND DOSE-
RESPONSE APPROACHES FOR NUCLEAR
RECEPTORS. ​D. Schrenk 5 , R. Budinsky 1 , J.
Corton 3 , C. Elcombe 2 , J. Klaunig 4 and D. Wolf 3 .
1
Dow, Midland, MI, 2 CRX Bioscience, Dundee,
Scotland, United Kingdom, 3 U.S. EPA, Research
Triangle Park, NC, 4 Indiana University, Indianapolis,
IN and 5 University of Kaiserslautern, Kaiserslautern,
Germany.
#368 Poster Board Number.....................................725
TESTING STRUCTURE-BINDING
PREDICTIONS FROM COMPARATIVE
MODELING OF THE AHR LIGAND-
BINDING DOMAIN: STUDIES WITH
ZEBRAFISH AHR1a. ​S. I. Karchner 1 , D. G.
Franks 1 , A. Pandini 3 , A. A. Soshilov 2 , L. Bonati 3 ,
M. S. Denison 2 and M. E. Hahn 1 . 1 Woods Hole
Oceanographic Institution, Woods Hole, MA,
2
University of California Davis, CA and 3 Universita’
degli Studi di Milano-Bicocca, Milan, Italy.
#369 Poster Board Number.....................................726
DISCOVERING TRANSCRIPTIONAL
REGULATORS OF CYTOCHROME P450 1A
THROUGH SIRNA HIGH-THROUGHPUT
SCREENINGS. ​P. Solaimani 1 , O. Hankinson 1
and R. Damoiseaux 2 . 1 Molecular Toxicology
IDP, University of California Los Angeles, Los
Angeles, CA and 2 California NanoSystems Institute,
University of California Los Angeles, Los Angeles,
CA.
#370 Poster Board Number.....................................727
EPITHELIAL REGULATION OF
PEROXISOME PROLIFERATOR-
ACTIVATED RECEPTOR γ BY CHEMICAL
RIBOSOME-INACTIVATING STRESS. ​S.
Park, H. Choi, H. Yang and Y. Moon. Department
of Microbiology and Immunology, Pusan National
University School of Medicine and Medical Research
institute, Yangsan, Republic of Korea.
#371 Poster Board Number.....................................728
FOXA1 IS ESSENTIAL FOR THE AHR-
DEPENDENT REGULATION OF CYCLIN
G2. ​S. Ahmed, S. Al-Saigh and J. Matthews.
Pharmacology & Toxicology, University of Toronto,
Toronto, ON, Canada.
#372 Poster Board Number.....................................729
DIVERGENT ROLES FOR THE ARYL
HYDROCARBON RECEPTOR AND ARYL
HYDROCARBON RECEPTOR NUCLEAR
TRANSLOCATOR IN ESTROGEN
SIGNALING. ​M. P. Labrecque 1 , K. J. Tam 1 , B. D.
Hollingshead 2 , G. G. Prefontaine 1 , G. H. Perdew 2
and T. V. Beischlag 1 . 1 Faculty of Health Sciences,
Simon Fraser University, Burnaby, BC, Canada
and 2 Veterinary and Biomedical Sciences, The
Pennsylvania State University, University Park, PA.
#373 Poster Board Number.....................................730
THE ARYL HYDROCARBON RECEPTOR
INTERACTS WITH ATP5α1, A SUBUNIT
OF THE ATP SYNTHASE COMPLEX,
AND MODULATES MITOCHONDRIAL
FUNCTION. ​D. M. Tappenden 1,2 , S. Lynn 1,2 , R.
B. Crawford 3 , N. E. Kamniski 2,3 , R. S. Thomas 4
and J. J. LaPres 1,2 . 1 Biochemistry, Michigan State
University, East Lansing, MI, 2 Center for Integrative
Toxicology, Michigan State University, East Lansing,
MI, 3 Department of Pharmacology and Toxicology,
Michigan State University, East Lansing, MI and
4
The Hamner Institutes for Health Sciences, Research
Triangle Park, NC.
#374 Poster Board Number.....................................731
REGULATION OF CHOLESTEROL
BIOSYNTHETIC GENE EXPRESSION
BY AH RECEPTOR THROUGH A DNA-
INDEPENDENT MECHANISM. ​R. Tanos, R.
D. Patel and G. H. Perdew. Penn State University,
University Park, PA.
#375 Poster Board Number.....................................732
MULTI-SPECIES ANALYSES OF DIRECT
ACTIVATORS OF THE CONSTITUTIVE
ANDROSTANE RECEPTOR. ​C. Omiecinski 1 ,
D. M. Coslo 1 , T. Chen 1 and R. C. Peffer 2 . 1 Center
for Molecular Toxicology, Penn State University,
University Park, PA and 2 Syngenta Crop Protection,
Inc., Greensboro, NC.
#376 Poster Board Number.....................................733
A FUNCTIONAL CROSSTALK BETWEEN
CAR AND LXR LINKS XENOBIOTIC
RESPONSE AND LIPOGENESIS. ​W. Xie,
T. Wada and Y. Zhai. University of Pittsburgh,
Pittsburgh, PA.
146
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