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50 th Anniversary Annual Meeting and ToxExpo Program Description (Continued) Wednesday Abstract # Abstract # #2304 Poster Board Number.....................................502 IN VITRO EXPOSURE AND EVALUATION OF MILITARY FUELS AND BIOFUELS. K. L. Mumy 1 , T. L. Doyle 1 , M. R. Okolica 1 , R. P. Adkins 1 and G. T. Eldridge 2 . 1 Naval Medical Research Unit - Dayton, Wright-Patterson AFB, OH and 2 Naval Air Warfare Center Aircraft Division, Patuxent River, MD. #2305 Poster Board Number.....................................503 DOSE-RESPONSE EVALUATION OF NON- ADDITIVE HEPATIC EFFECTS OF PCB153 AND TCDD IN MICE. A. K. Kopec 1,2 , M. L. D’Souza 1,2 , B. D. Mets 1 , L. D. Burgoon 1,2 , J. R. Harkema 2,3 , C. Tashiro 4 , D. Potter 4 , B. Sharratt 4 , S. E. Reese 5 , K. J. Archer 5 and T. R. Zacharewski 1,2 . 1 Biochemistry & Molecular Biology, Michigan State University, East Lansing, MI, 2 Center for Integrative Toxicology, Michigan State University, East Lansing, MI, 3 Pathobiology & Diagnostic Investigations, Michigan State University, East Lansing, MI, 4 Wellington Laboratories, Inc., Guelph, ON, Canada and 5 Biostatistics, Virginia Commonwealth University, Richmond, VA. #2306 Poster Board Number.....................................504 DETERMINING A ROBUST D-OPTIMAL DESIGN FOR TESTING FOR DEPARTURE FROM ADDITIVITY IN A MIXTURE OF FOUR PFAAS. C. Carr 1 , C. Gennings 1 , B. D. Abbott 2 , J. E. Schmid 2 , W. Wan 1 , L. Burgoon 2 , C. J. Wolf 2 and C. Lau 2 . 1 Biostatistics, Virginia Commonwealth University, Richmond, VA and 2 NHEERL, U.S. EPA, Research Triangle Park, NC. #2307 Poster Board Number.....................................505 PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODELING OF TWO BINARY MIXTURES: METABOLIC ACTIVATION OF CARBON TETRACHLORIDE BY TRICHLOROETHYLENE AND METABOLIC INHIBITION OF CHLOROFORM BY TRICHLOROETHYLENE. M. V. Evans 1 , H. M. Yang 2 , K. A. Yokley 3 , A. McDonald 1 , Y. M. Sey 1 , C. R. Eklund 1 and J. Simmons 1 . 1 NHEERL/ORD, U.S. EPA, Research Triangle Park, NC, 2 NCEA/ORD, U.S. EPA, Washington, D.C. and 3 Mathematics and Statistics, Elon University, Elon, NC. #2308 Poster Board Number.....................................506 INTEGRATED MULTI-DISCIPLINARY ASSESSMENT OF ENVIRONMENTALLY REALISTIC COMPLEX MIXTURES OF DRINKING WATER DISINFECTION BY-PRODUCTS (DBPS) (THE 4LAB STUDY). J. Simmons 1 , M. G. Narotsky 1 , L. K. Teuschler 2 , J. G. Pressman 3 , E. S. Hunter 1 , G. E. Rice 2 , G. R. Klinefelter 1 , J. M. Goldman 1 , T. F. Speth 3 , L. F. Strader 1 , R. J. Miltner 3 , S. Parvez 2 , A. McDonald 1 , D. S. Best 1 , C. A. Dingus 4 and S. D. Richardson 5 . 1 NHEERL/ORD, U.S. EPA, Research Triangle Park, NC, 2 NCEAORD, U.S. EPA, Cincinnati, OH, 3 NRMRL/ORD, U.S. EPA, Cincinnati, OH, 4 Battelle, Columbus, OH and 5 NERL/ORD, U.S. EPA, Athens, GA. #2309 Poster Board Number.....................................507 A FOUR-STEP APPROACH FOR EVALUATION OF DOSE-ADDITIVITY. R. C. Hertzberg 1 , Y. Pan 2 , R. Li 2 , L. T. Haber 3 , R. Lyles 2 , V. C. Moser 4 , D. W. Herr 4 and J. Simmons 4 . 1 Biomathematics Consulting, Atlanta, GA, 2 Department of Statistics, Emory University, Atlanta, GA, 3 Toxicology Excellence for Risk Assessment, Atlanta, GA and 4 NHEERL, U.S. EPA, Research Triangle Park, NC. #2310 Poster Board Number.....................................508 TOXICITY OF TUNGSTEN AND COBALT MIXTURES IN EMBRYONIC ZEBRAFISH. J. L. Freeman, J. M. Schultheis, D. R. Robbins and S. M. Peterson. Health Sciences, Purdue University, West Lafayette, IN. #2311 Poster Board Number.....................................509 SIMULTANEOUS EXTRACTION AND DETECTION OF BISPHENOL A AND GENISTEIN. J. Coughlin 1,2,3 and B. Buckley 1,2,3 . 1 Toxicology, Rutgers University, Piscataway, NJ, 2 JGPT, Rutgers University, Piscataway, NJ and 3 Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, NJ. #2312 Poster Board Number.....................................510 REACTIVITY OF SELECTED OSTEOLATHYROGENS WITH A MODEL COFACTOR FOR LYSYL OXIDASE. H. Bensinger 1 , N. Genco 1 , R. G. Bergosh 2 and D. A. Dawson 1 . 1 Biology/Toxicology, Ashland University, Ashland, OH and 2 Chemistry, Geology, and Physics, Ashland University, Ashland, OH. Sponsor: D. Fort. #2313 Poster Board Number.....................................511 THE SYNERGISTIC EFFECT OF SODIUM CHLORITE AND BROMOCHLOROACETIC ACID ON BROMATE-INDUCED RENAL CELL DEATH. X. Zhang 1 , R. J. Bull 2 , J. A. Cotruvo 3 , J. Fisher 4 and B. S. Cummings 1 . 1 Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, GA, 2 MoBull Consulting, Richland, WA, 3 Joseph Cotruvo & Associates, LLC, Washington, D.C. and 4 National Center for Toxicological Research, U.S. FDA, Jefferson, AR. #2314 Poster Board Number.....................................512 CELL SIGNAL TRANSDUCTION TO PREDICT MIXTURE INTERACTIONS. J. Boyd, X. Gao, H. Williams, C. Kinzer and J. Vrana. Bennett Department of Chemistry, West Virginia University, Morgantown, WV. #2315 Poster Board Number.....................................513 PIFITHRIN-α INCREASES IGF- 1R INHIBITOR MEDIATED HEPG2 HEPATOCARCINOMA DEATH. X. Gao, H. Williams, C. Kinzer, J. Vrana and J. Boyd. Bennett Department of Chemistry, West Virginia University, Morgantown, WV. #2316 Poster Board Number.....................................514 PBPK MODELING OF THE AGGREGATE AND CUMULATIVE EXPOSURES OF RATS TO TOLUENE, N-HEXANE, CYCLOHEXANE, AND ISOOCTANE. N. Kaveh, M. Gagné, G. Charest-Tardif, R. Tardif and K. Krishnan. Université de Montréal, Montréal, QC, Canada. 320 Education-Career Development Sessions Exhibitor Hosted Sessions Featured Sessions Historical Highlights Informational Sessions Platform Sessions
Society of Toxicology 2011 Program Description (Continued) Abstract # Wednesday Afternoon, March 9 1:00 PM to 4:30 PM Exhibit Hall Poster Session: Mechanisms of Aspiration Injury and Airway Disease Chairperson(s): Deepak Bhalla, Wayne State University, Detroit, MI. Displayed: 1:00 PM–4:30 PM Author Attended: 2:45 PM–4:30 PM #2317 Poster Board Number.....................................516 NAIL MANGANESE AS A BIOMARKER OF WELDING FUME EXPOSURE. J. M. Antonini, J. R. Roberts and K. Sriram. NIOSH, Morgantown, WV. #2318 Poster Board Number.....................................517 PERIPHERAL BLOOD GENE EXPRESSION PROFILING REVEALS SILICA-INDUCED PULMONARY TOXICITY. R. Sellamuthu, C. Umbright, J. Roberts, R. Chapman, S. Young, D. Richardson, D. Leonard, W. McKinney, B. Chen, D. Frazer, S. Li, M. Kashon and P. Joseph. National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV. #2319 Poster Board Number.....................................518 BIOACTIVATION OF THE NASAL TOXICANT 2, 6-DICHLOROBENZONITRILE: AN ASSESSMENT OF METABOLIC ACTIVITY IN HUMAN NASAL MUCOSA AND IDENTIFICATION OF BIOMARKERS OF EXPOSURE AND POTENTIAL TOXICITY. F. Xie 1,2 , X. Zhou 1 , J. D’Agostino 1 , D. Spink 1 and X. Ding 1 . 1 Wadsworth Center, New York State Department of Health, Albany, NY and 2 School of Public Health, State University of New York at Albany, Albany, NY. #2320 Poster Board Number.....................................519 SYSTEMIC UPTAKE OF 14 C 2, 3-BUTANEDIONE ADMINISTERED BY INTRATRACHEAL INSTILLATION IN MALE SPRAGUE-DAWLEY RATS AND OROPHARYNGEAL ASPIRATION IN MALE B6C3F1 MICE. T. Fennell 1 , D. Morgan 2 , S. Watson 1 and S. Waidyanatha 2 . 1 RTI International, Research Triangle Park, NC and 2 National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC. #2321 Poster Board Number.....................................520 RESVERATROL, AN AHR LIGAND, ALLEVIATES BACTERIAL ENTEROTOXIN- INDUCED ACUTE LUNG INJURY VIA UPREGULATION OF MIRNA 155 AND SUBSEQUENT INCREASE IN MYELOID- DERIVED SUPPRESSOR CELLS. S. A. Rieder, P. Nagarkatti and M. Nagarkatti. Pathology Microbiology and Immunology, University of South Carolina, Columbia, SC. Abstract # #2322 Poster Board Number.....................................521 MOLECULAR PATHWAYS OF PULMONARY INFLAMMATION FOLLOWING ASPIRATION AND INHALATION OF STAINLESS STEEL WELDING FUME IN MICE. P. C. Zeidler-Erdely, A. Erdely, M. Kashon, S. Li and J. Antonini. HELD, NIOSH, Morgantown, WV. #2323 Poster Board Number.....................................522 EFFECTS OF PARTICULATE AIR POLLUTION DURING BEIJING OLYMPIC GAMES IN A MOUSE MODEL. K. Tzan 1 , X. Xu 1 , S. Jiang 1 , J. Aronovsky 1 , A. Wang 2 , S. Rajagopalan 2,3 and Q. Sun 1,2,3 . 1 Public Health, The Ohio State University, Columbus, OH, 2 Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH and 3 Cardiology, The Ohio State University, Columbus, OH. #2324 Poster Board Number.....................................523 OVER-EXPRESSION OF THE NF-κB MEMBER RELB DAMPENS THE PRO-INFLAMMATORY EFFECTS OF LONG- TERM CIGARETTE SMOKE EXPOSURE. D. McMillan 1,3 , T. H. Thatcher 3,4 , S. Maggirwar 2 , P. J. Sime 1,3,4 and R. P. Phipps 1,2,3 . 1 Environmental Medicine, University of Rochester, Rochester, NY, 2 Microbiology and Immunology, University of Rochester, Rochester, NY, 3 Lung Biology and Disease, University of Rochester, Rochester, NY and 4 Pulmonary and Critical Care Medicine, University of Rochester, Rochester, NY. #2325 Poster Board Number.....................................524 ADJUVANT EFFECT OF 1Ç3-β-GLUCAN (ZYMOSAN) EXPOSURE IN A MOUSE OVALBUMIN ALLERGY MODEL. S. Young, M. Wolfarth, J. R. Roberts, M. L. Kashon and J. M. Antonini. NIOSH, Morgantown, WV. #2326 Poster Board Number.....................................525 ROLE OF SURFACTANT PROTEIN-D (SP-D) IN REGULATING MACROPHAGE PHENOTYPE, INFLAMMATION, AND LUNG FUNCTION IN ELDERLY MICE FOLLOWING OZONE (O3) INHALATION. A. M. Groves 1 , J. D. Laskin 2 , A. J. Gow 1 and D. L. Laskin 1 . 1 Rutgers University, Piscataway, NJ and 2 UMDNJ-RWJ Medical School, Piscataway, NJ. #2327 Poster Board Number.....................................526 GLUTATHIONE DEPLETION POTENTIATES CIGARETTE SMOKE INDUCED AIRWAY INFLAMMATION. B. J. Day 1,2,3 , E. Min 1 and N. S. Gould 1,2 . 1 Medicine, National Jewish Health, Denver, CO. 2 Pharmaceutical Sciences, University of Colorado AMC, Aurora, CO and 3 Medicine, University of Colorado AMC, Aurora, CO. #2328 Poster Board Number.....................................527 THE GLUTATHIONE SYNTHESIS GENE GCLM MODULATES PULMONARY INFLAMMATION FOLLOWING INTRANASAL INSTILLATION OF DIESEL EXHAUST PARTICULATE. C. Weldy 1 , C. C. White 1 , D. P. Cox 1 , H. Wilkerson 1 , S. Gill 2 , W. Parks 2 and T. J. Kavanagh 1 . 1 Environmental and Occupational Health Sciences, University of Washington, Seattle, WA and 2 Pulmonary and Critical Care Medicine, University of Washington, Seattle, WA. Wednesday Poster Sessions Regional Interest Session Roundtable Sessions Symposium Sessions Thematic Sessions Workshop Sessions 321
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50 th Anniversary Annual Meeting &
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Scientific Program Overview A page
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9:00 AM-12:30 PM POSTER SESSionS
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March 6-10, 2011 Walter E. Washingt
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Celebration Activities Historical H
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of the Society Regional Chapter Yea
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SOT Presidents 1961-2011 1966 1967
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The SOT Council Thanks and Recogniz
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of the Past 50 Years 2003 Michael D
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Toxicological Sciences The Official
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2011 SOT 50 th Anniversary Featured
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Society of Toxicology 2011 ToxExpo
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Creating a Safer and Healthier Worl
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SOT Job Bank YOUR RECRUITMENT AND E
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Society of Toxicology 2011 SOT 2011
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Society of Toxicology 2011 Outreach
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Society of Toxicology 2011 2010-201
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Society of Toxicology 2011 Elected
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