Program - Society of Toxicology

Society of Toxicology 2011
Program Description (Continued)
Abstract #
#2341 Poster Board Number.....................................604
CHEMICAL DISPERSANTS USED IN THE
GULF OF MEXICO ARE CYTOTOXIC
AND GENOTOXIC TO HUMAN SKIN
FIBROBLASTS. ​J. Wise 1,2 , S. Wise 1,2,3 , H. Xie 1,2,3
and J. P. Wise 1,2,3 . 1 Wise Laboratory of Environmental
and Genetic Toxicology, University of Southern
Maine, Portland, ME, 2 Maine Center for Toxicology
and Environmental Health, University of Southern
Maine, Portland, ME and 3 Department of Applied
Medical Science, University of Southern Maine,
Portland, ME.
#2342 Poster Board Number.....................................605
DEVELOPING A WHALE CELL LINE AT
SEA TO EVALUATE THE CYTOTOXICITY
AND GENOTOXICITY OF CHEMICAL
DISPERSANTS USED IN THE GULF OF
MEXICO OIL CRISIS. ​C. F. Wise 1,2,4 , M.
Braun 1,2,4 , J. P. Wise 1,2,4 , S. S. Wise 1,2,3 , I. Kerr 2,4 ,
H. Xie 1,2,3 and J. P. Wise 1,2,3 . 1 Wise Laboratory of
Environmental and Genetic Toxicology, University
of Southern Maine, Portland, ME, 2 Maine Center for
Toxicology and Environmental Health, University
of Southern Maine, Portland, ME, 3 Department of
Applied Medical Science, University of Southern
Maine, Portland, ME and 4 Ocean Alliance, Lincoln,
MA.
Wednesday Afternoon, March 9
1:00 PM to 4:30 PM
Exhibit Hall
Poster Session: Endocrine Toxicology
Chairperson(s): Tammy Stoker, U.S. EPA, Research Triangle Park, NC.
Displayed: 1:00 PM–4:30 PM
Author Attended: 2:45 PM–4:30 PM
#2343 Poster Board Number.....................................614
BONE HOMEOSTASIS IS NOT ALTERED
IN MCHR1-DEFICIENT MICE. ​B. Gemzik 1 ,
J. A. Tamasi 2 , J. J. Devenny 2 , B. J. Murphy 2 , W. N.
Washburn 3 and B. D. Car 1 . 1 Discovery Toxicology,
Bristol-Myers Squibb Company, Princeton, NJ,
2
Discovery Biology, Bristol-Myers Squibb Company,
Princeton, NJ and 3 Discovery Chemistry, Bristol-
Myers Squibb Company, Princeton, NJ.
#2344 Poster Board Number.....................................615
A NOVEL SENSITIVE AND SELECTIVE
REAL-TIME CELLULAR ASSAY FOR
DETECTION OF ENDOCRINE DISRUPTORS
USING NATIVE ENDOCRINE SIGNALING
PATHWAYS. ​C. Jin 1 , Y. Abassi 1 , X. Xu 1 , X.
Wang 1 , W. Zhang 2 and S. Gabos 2 . 1 Acea Biosciences,
San Diego, CA and 2 Alberta Health and Wellness,
Edmonton, AB, Canada. Sponsor: M. Lo.
#2345 Poster Board Number.....................................616
THE IMPACT OF EPIDERMAL GROWTH
FACTOR RECEPTOR INHIBITION ON
ENERGY HOMEOSTASIS. ​M. Biggs 1 , D.
Threadgill 2 , T. Ghashghaei 3 and T. Lee 4 . 1 Toxicology,
University of North Carolina at Chapel Hill,
Chapel Hill, NC, 2 Genetics, North Carolina State
University, Raleigh, NC, 3 Department of Molecular
and Biomedical Sciences, North Carolina State
University, Raleigh, NC and 4 Genetics, University of
North Carolina at Chapel Hill, Chapel Hill, NC.
Abstract #
#2346 Poster Board Number.....................................617
SCIENTIFICALLY RELEVANT
INFORMATION TO EVALUATE THE
ENDOCRINE DISRUPTING POTENTIAL
OF ISOPHORONE. ​N. M. Berdasco and D. R.
Geter. Toxicology and Environmental Research and
Consulting, The Dow Chemical Company, Midland,
MI.
#2347 Poster Board Number.....................................618
EXENATIDE AND SITAGLIPTIN: THEIR
ROLE IN AUTOPHAGOSOME REGULATED
TOXICITY IN PANCREATITIS. ​R. Rouse, L.
Zhang and D. A. Volpe. U.S. FDA, Silver Spring,
MD.
#2348 Poster Board Number.....................................619
IMPROVING THE IN VIVO PREDICTIVE
VALUE OF THE ER-CALUX
BIOASSAY BY COMBINING IN VITRO
ESTROGENICITY RESULTS WITH KINETIC
CHARACTERISTICS OF ESTROGENIC
COMPOUNDS. ​W. Brand 1 , A. Punt 1,2 , A. J. Murk 2 ,
M. Schriks 1 , A. P. van Wezel 1 and M. B. Heringa 1 .
1
KWR Watercycle Research Institute, Nieuwegein,
Netherlands and 2 Division of Toxicology,
Wageningen University, Wageningen, Netherlands.
#2349 Poster Board Number.....................................620
PCB-153 AND BDE-47 INCREASE
THYROXINE (T ) CATABOLISM IN RAT
4
AND HUMAN HEPATOCYTES. ​V. M.
Richardson 1,2 and M. J. DeVito 3 . 1 ORD/NHEERL/
ISTD, U.S. EPA, Research Triangle Park, NC,
2
Curriculum in Toxicology, University of North
Carolina at Chapel Hill, Chapel Hill, NC and
3
Toxicology Branch, NIEHS/NTP, Research Triangle
Park, NC.
#2350 Poster Board Number.....................................621
TRICLOSAN DECREASES RAT
THYROXINE: MODE-OF-ACTION,
DEVELOPMENTAL SUSCEPTIBILITY AND
HUMAN RELEVANCE. ​K. B. Paul 1,2 , J. M.
Hedge 2 , S. O. Simmons 2 , M. J. DeVito 3,1 and K. M.
Crofton 2,1 . 1 Toxicology, University of North Carolina
at Chapel Hill, Chapel Hill, NC, 2 Integrated Systems
Toxicology Division, NHEERL, ORD, U.S. EPA,
Research Triangle Park, NC and 3 NTP, NIEHS,
Research Triangle Park, NC.
#2351 Poster Board Number.....................................622
EVALUATION OF SUBSTANCES
ROUTINELY TAKEN IN EVERYDAY LIFE
IN THE H295R STEROIDOGENESIS ASSAY. ​
H. Tinwell, S. Colombel and R. Bars. Research
Toxicology, Bayer SAS, Sophia Antipolis Cedex,
France.
#2352 Poster Board Number.....................................623
BISPHENOL A DISRUPTS STEROIDOGENIC
PATHWAYS AND ADRENAL AND SEX
HORMONE SECRETION IN THE HUMAN
ADRENOCORTICAL H295R CELL LINE. ​A.
Oskarsson 1 ,. Ohlsson 1 , C. Jansson 2 and E. Ullerås 1 .
1
Department of Biomedical Sciences and Veterinary
Public Health, Swedish University of Agricultural
Sciences, Uppsala, Sweden and 2 Department
of Aquatic Sciences and Assessment, Swedish
University of Agricultural Sciences, Uppsala,
Sweden.
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