Program - Society of Toxicology

Society of Toxicology 2011
Program Description (Continued)
Abstract #
#2552 Poster Board Number.....................................146
LEYDIG CELLS RESPONSES TO
STIMULATION WITH LUTEINIZING
HORMONE IN CULTURES FROM RATS OF
DIFFERENT AGE. ​P. Balbuena, J. L. Campbell,
R. Clewell and H. J. Clewell. The Hamner Institutes
of Health Sciences, Research Triangle Park, NC.
#2553 Poster Board Number.....................................147
AN ORGANOTYPIC MICROLIVER
PLATFORM FOR HIGH-THROUGHPUT
DRUG TESTING. ​S. Messner 1 , B. Machi 1 ,
S. Hammad 2 , J. M. Kelm 1 , J. G. Hengstler 2 and
W. Moritz 1 . 1 InSphero AG, Zürich, Switzerland
and 2 IfADo Dortmund, Technical University of
Dortmund, Dortmund, Germany. Sponsor: C. Corton.
#2554 Poster Board Number.....................................148
QUANTIFICATION OF UVA-INDUCED
REACTIVE OXYGEN SPECIES IN PRIMARY
HUMAN KERATINOCYTES TREATED
WITH ANTIOXIDANTS. ​K. Norman, H.
Inglis and G. Mun. Institute for In Vitro Sciences,
Gaithersburg, MD. Sponsor: E. Dahl.
#2555 Poster Board Number.....................................149
IN VITRO ASSESSMENT OF SKIN
IRRITATION POTENTIAL OF SURFACTANT
BASED FORMULATIONS USING 3-D
SKIN RECONSTRUCTED TISSUES AND
CYTOKINE EXPRESSION ANALYSIS. ​L.
Gandolfi 1 , N. Tierney 1 , D. Johnson 1 , R. Walters 1 ,
M. Fevola 1 , E. Gunn 1 , K. Martin 1 , A. Kong 2 , A.
Hilberer 2 , N. Barnes 2 , N. Wilt 2 , J. R. Nash 2 , H.
Inglis 2 , H. Raabe 2 and G. Costin 2 . 1 Johnson &
Johnson, Skillman, NJ and 2 Institute for In Vitro
Sciences, Inc., Gaithersburg, MD.
#2556 Poster Board Number.....................................150
USE OF EPIDERM FULL THICKNESS (EFT)
SKIN CULTURES AS AN IN VITRO MODEL
FOR WOUND HEALING. ​P. Hayden2, M.
Sachdeva 1 , P. P. Shah 1 , U. S. Desai 1 , R. Patlolla 1 and
M. Klausner 2 . 1 Pharmacy, Florida A&M University,
Tallahassee, FL and 2 MatTek Corporation, Ashland,
MA.
#2557 Poster Board Number.....................................151
IN VITRO BILIARY CLEARANCE OF
PERFLUOROOCTANOATE IN SANDWICH-
CULTURED HEPATOCYTES FROM RATS. ​
D. Nabb, R. Mingoia and X. Han. DuPont Haskell
Global Centers for Health & Environmental
Sciences, Newark, DE.
#2558 Poster Board Number.....................................152
IDENTIFICATION OF NOVEL
BIOMARKERS OF FORMALDEHYDE
TOXICITY IN HUMANS USING
FUNCTIONAL TOXICOGENOMICS IN
YEAST. ​M. North 1 , C. Romero 1,2 , A. Loguinov 1 , M.
T. Smith 2 , L. Zhang 2 and C. D. Vulpe 1 . 1 Department
of Nutritional Science & Toxicology, The University
of California Berkeley, Berkeley, CA and 2 Division
of Environmental Health Sciences, School of Public
Health, The University of California Berkeley,
Berkeley, CA.
Abstract #
#2559 Poster Board Number.....................................153
VALIDATION RESULTS AND METHODS
FOR IMPROVING IN VITRO TIER 1
ENDOCRINE DISRUPTION SCREENING
ASSAYS. ​C. Toole, D. P. Blakeman, N. Nichols,
M. Clark, H. Wagner, B. Wallace and J. M. McKim.
CeeTox, Inc., Kalamazoo, MI.
#2560 Poster Board Number.....................................154
A NOVEL STRATEGY FOR IN VITRO
ASSAY PLATFORM TO PREDICT SKIN
SENSITIZING POTENTIAL OF BROAD
RAW MATERIALS. ​M. Miyazawa 1 , Y. Nukada 1 ,
K. Saito 1 , H. Sakaguchi 1 , N. Nishiyama 1 and F.
Gerberick 2 . 1 Kao Corporation, Tochigi, Japan and
2
Procter & Gamble Company, Cincinnati, OH.
#2561 Poster Board Number.....................................155
GENE EXPRESSION ANALYSIS OF
PRECISION-CUT HUMAN LIVER SLICES
INDICATE STABLE EXPRESSION OF
HEPATOXICITY RELATED GENES. ​M.
G. Elferink 2 , P. Olinga 1 , E. M. van Leeuwen 3 ,
S. Bauerschmidt 3 , J. Polman 3 , W. G. Schoonen 4 ,
S. H. Heisterkamp 5,6 and G. M. Groothuis 2 .
1
Pharmaceutical Technology and Biopharmacy,
Groningen Research Institute for Pharmacy,
Groningen, Netherlands, 2 Pharmacokinetics,
Toxicology and Targeting, Groningen Research
Institute for Pharmacy, Groningen, Netherlands,
3
Molecular Design and Informatics, MSD, Oss,
Netherlands, 4 Toxicology &Drug Disposition,
MSD, Oss, Netherlands, 5 Biostatistics and Research
Decision Sciences, MSD, OSS, Netherlands and
6
Bioinformatics Centre, University of Groningen,
Groningen, Netherlands. Sponsor: A. Vickers.
#2562 Poster Board Number.....................................156
MEDIA SERUM LEVELS AND IN VITRO
HEPATIC ABSORPTION OF LINDANE. ​E.
L. Croom and R. A. Pegram. Office of Research and
Development, National Health and Environmental
Effects Research Laboratory, U.S. EPA, Research
Triangle Park, NC.
#2563 Poster Board Number.....................................157
AN IN VITRO MODEL FOR THE STUDY OF
BACTERIAL COLONIZATION OF HUMAN
EXTRAPLACENTAL MEMBRANES:
ROLE OF ANTIMICROBIAL PEPTIDES. ​E.
Boldenow 1 , S. Jones 1 , C. Xi 1 , R. Lieberman 2 and
R. Loch-Caruso 1 . 1 Environmental Health Sciences,
University of Michigan, Ann Arbor, MI and
2
Obstetrics and Gynecology, University of Michigan,
Ann Arbor, MI.
#2564 Poster Board Number.....................................158
EVALUATION OF AN ORAL CARE
PRODUCT SAFETY SCREENING PROGRAM
UTILIZING THE IN VITRO SKINETHIC
HUMAN GINGIVAL EPITHELIUM (RHG)
AND ORAL BUCCAL (RHO) MODELS. ​
L. Wurzburger 1 , P. Kazmi 1 , T. Re 1 , A. Alonso 2 ,
B. Bertino 2 , N. Barnes 3 , A. de Brugerolle de
Fraissinette 2 , A. Hilberer 3 , H. Raabe 3 , N. Wilt 3 and
V. Srinivasan 1 . 1 L’Oreal USA Products, Clark, NJ,
2
SkinEthic Laboratories, Nice, France and 3 Institute
for In Vitro Sciences, Inc., Gaithersburg, MD.
Thursday
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