Program - Society of Toxicology

Society of Toxicology 2011
Program Description (Continued)
Abstract #
#1076 Poster Board Number.....................................360
CHARACTERIZATION OF A NOVEL
SERIES OF ENDOTHELIN-A RECEPTOR
ANTAGONISTS IN THE SETTING OF
INFECTION ASSOCIATED PRETERM
BIRTH. ​N. S. Olgun, H. J. Patel, R. A. Stephani
and S. E. Reznik. Pharmaceutical Science, St. John’s
University, Jamaica, NY.
Tuesday Morning, March 8
9:00 AM to 12:30 PM
Exhibit Hall
Poster Session: Hepatotoxicity
Chairperson(s): Angela Slitt, University of Rhode Island, Kingston, RI.
Displayed: 9:00 AM–12:30 PM
Author Attended: 9:00 AM–11:00 AM
#1077 Poster Board Number.....................................401
AFFECTS OF ALCOHOL CIRRHOSIS AND
DIABETES ON DRUG TRANSPORTER
EXPRESSION IN HUMAN LIVER. ​V. R. More 1 ,
Z. Lu 2 , N. Cherrington 3 and A. Slitt 1 . 1 Biomedical and
Pharmaceutical Sciences, University of Rhode Island,
Kingston, RI, 2 Statistical Consulting Laboratory,
University of Arizona, Tucson, AZ and 3 Department
of Pharmacology and Toxicology, University of
Arizona, Tucson, AZ.
#1078 Poster Board Number.....................................402
PERINATAL BISPHENOL A (BPA)
EXPOSURE ALTERS LIVER ATP-BINDING
CASSETTE (ABC) TRANSPORTER
EXPRESSION IN MICE. ​A. C. Donepudi 1 , M.
Meloon 1 , P. T. Sieli 3 , C. S. Rosenfeld 2 and A. L. Slitt 1 .
1
Department of Biomedical and Pharmaceutical
Sciences, University of Rhode Island, Kingston, RI,
2
Department of Biomedical Sciences, University of
Missouri, Columbia, MO and 3 Bond Life Sciences
Center, University of Missouri, Columbia, MO.
#1079 Poster Board Number.....................................403
OPPOSING EFFECTS OF DIABETES
AND PREGNANCY ON HEPATOBILIARY
EFFLUX TRANSPORTER EXPRESSION. ​A.
L. Slitt 1 , J. Xu 1 and L. M. Aleksunes 2 . 1 Biomedical
and Pharmaceutical Sciences, University of Rhode
Island, Kingston, RI and 2 Pharmacology and
Toxicology, Rutgers University, Piscataway, NJ.
#1080 Poster Board Number.....................................404
EFFECT OF TROGLITAZONE (TRO)
ON ENDOGENOUS BILE ACID (BA)
DISPOSITION IN RAT AND HUMAN
SANDWICH-CULTURED HEPATOCYTES
(SCH). ​T. Marion 1 , C. Perry 2 , R. L. St. Claire
III 2 and K. Brouwer 1,3 . 1 Curriculum in Toxicology,
University of North Carolina at Chapel Hill, Chapel
Hill, NC, 2 Qualyst, Inc., Research Triangle Park, NC
and 3 Eshelman School of Pharmacy, University of
North Carolina at Chapel Hill, Chapel Hill, NC.
Abstract #
#1081 Poster Board Number.....................................405
EFFECTS OF SEEDING DENSITY AND DAYS
IN CULTURE ON BILE ACID TRANSPORT
AND Mrp4 EXPRESSION IN SANDWICH-
CULTURED MOUSE HEPATOCYTES ARE
NOT A RESULT OF OXIDATIVE STRESS. ​B.
C. Ferslew 1 , X. Gu 2 , B. Swift 3 , J. E. Manautou 2 and
K. L. Brouwer 1 . 1 Eshelman School of Pharmacy,
University of North Carolina at Chapel Hill, Chapel
Hill, NC, 2 Department of Pharmaceutical Sciences,
University of Connecticut, Storrs, CT and 3 PKPD
and Drug Metabolism, Allergan, Inc., Irvine, CA.
#1082 Poster Board Number.....................................406
THE CELL SURFACE MARKER CD90
IDENTIFIES A SUBSET OF HEPATOCYTES
PRIMED FOR INCREASED MATRIX
PRODUCTION: IMPLICATIONS FOR
ETHANOL-INDUCED LIVER FIBROSIS. ​
B. A. Hocevar, Z. Wang and L. M. Kamendulis.
Department of Environmental Health, Indiana
University, Bloomington, IN.
#1083 Poster Board Number.....................................407
INVESTIGATING ER STRESS PATHWAY
ACTIVATION IN LIVER CELLS AND TISSUE
AS A TOXICOLOGICAL TOOL. ​M. Lafleur,
R. Hernandez and J. W. Lawrence. Investigative
Toxicology, Amgen, Thousand Oaks, CA. Sponsor:
S. Sawant.
#1084 Poster Board Number.....................................408
PROFILING IMPAIRED HEPATIC
ENDOPLASMIC RETICULUM
GLYCOSYLATION AS A CONSEQUENCE
OF ETHANOL INGESTION. ​J. Galligan 1 , K.
S. Fritz 2 , H. Tipney 1 , R. L. Smathers 2 , C. T. Shearn 2 ,
L. J. Hunter 1 and D. R. Petersen 2 . 1 Pharmacology,
University of Colorado Denver, Aurora, CO and
2
Toxicology, University of Colorado Denver, Aurora,
CO.
#1085 Poster Board Number.....................................409
CO-INVOLVEMENT OF MITOCHONDRIA
AND ENDOPLASMIC RETICULUM IN
ACROLEIN-INDUCED HEPATOCYTE
APOPTOSIS. ​D. Avila 1 , J. Zhang 1 , C. McClain 1,2 ,
S. Barve 1 and S. Joshi-Barve 1 . 1 Department of
Medicine/GI, University of Louisville, Louisville,
KY and 2 Robley Rex Veterans Administration
Medical Center, Louisville, KY.
#1086 Poster Board Number.....................................410
FRUCTOSE INDUCES URIC ACID
GENERATION AND MITOCHONDRIAL
DYSFUNCTION IN LIVER CELLS DURING
THE DEVELOPMENT OF METABOLIC
SYNDROME. ​M. A. Lanaspa, L. G. Sanchez-
Lozada, C. A. Roncal-Jimenez, N. Li, C. Cicerchi
and R. J. Johnson. Renal Medicine, University of
Colorado AMC, Denver, CO.
#1087 Poster Board Number.....................................411
DIBENZOFURAN EXPOSURE AFFECTS
MITOCHONDRIAL PERMEABILITY
TRANSITION INDUCTION. ​C. M. Palmeira,
F. V. Duarte, A. P. Gomes, A. M. Simões, A. T.
Varela, J. S. Teodoro and A. P. Rolo. Center for
Neurosciences and Cell Biology, Department of Life
Sciences, University of Coimbra, Coimbra, Portugal.
Tuesday
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