Program - Society of Toxicology

Society of Toxicology 2011
Program Description (Continued)
Abstract #
#2127 Poster Board Number.....................................907
MECHANISM OF ENHANCED HEME
OXYGENASE-1 (HO-1) ACTIVITY AND
THE ROLE OF HO-1 IN CONTROLLING
INFLAMMATORY CYTOKINE OUTPUT IN
LPS-STIMULATED MICROGLIA. ​C. A. Dodd,
I. I. Georgieva and N. M. Filipov. Physiology and
Pharmacology, University of Georgia, Athens, GA.
#2128 Poster Board Number.....................................908
OXIDATIVE INJURY AND EP2 SIGNALING
IN MANGANESE NEUROTOXICITY. ​D.
Milatovic 1 , Y. Yu 1 , S. Zaja-Milatovic 2 and M.
Aschner 1 . 1 Pediatrics, Vanderbilt University,
Nashville, TN and 2 Medicine, Vanderbilt University,
Nashville, TN.
#2129 Poster Board Number.....................................909
GLIAL INTERACTIONS AND
NEUROINFLAMMATION IN MANGANESE
NEUROTOXICITY. ​K. Sullivan 1 and R.
Tjalkens 1,2 . 1 Environmental and Radiological Health
Sciences, Colorado State University, Fort Collins,
CO and 2 Molecular and Cellular Biology, Colorado
State University, Fort Collins, CO.
#2130 Poster Board Number.....................................910
NOVEL NADPH OXIDASE
MODULATOR PROTECTS AGAINST
NEUROINFLAMMATION ASSOCIATED
WITH MANGANESE NEUROTOXICITY. ​
C. Hogan 1 , R. Gordon 1 , A. Kanthasamy 1 , V.
Anantharam 1 , B. Kalyanaraman 2 and A. G.
Kanthasamy 1 . 1 Biomedical Sciences, Iowa Center for
Advanced Neurotoxicology, Iowa State University,
Ames, IA and 2 Biophysics, Medical College of
Wisconsin, Milwaukee, WI.
#2131 Poster Board Number.....................................911
PROTEIN KINASE C IS INVOLVED IN
MANGANESE- MEDIATED DISRUPTION OF
GLUTAMINE TURNOVER IN ASTROCYTES. ​
M. Sidoryk-Wegrzynowicz 1 , E. Lee 2 and M.
Aschner 1 . 1 Department of Pediatrics, Vanderbilt
University Medical Center, Nashville, TN and
2
Department of Physiology, Meharry Medical
College, Nashville, TN.
#2132 Poster Board Number.....................................912
EXPRESSION OF MUTANT HUNTINGTIN
INCREASES ARGINASE ACTIVITY IN
MOUSE STRIATUM, BUT DECREASES
ITS SUSCEPTIBILITY TO MANGANESE
EXPOSURE. ​M. Wegrzynowicz 1,2 , H. K. Holt 1,2
and A. B. Bowman 1,2,3 . 1 Department of Neurology,
Vanderbilt University Medical Center, Nashville, TN,
2
Vanderbilt Kennedy Center, Vanderbilt University
Medical Center, Nashville, TN and 3 Center for
Molecular Toxicology, Vanderbilt University Medical
Center, Nashville, TN.
#2133 Poster Board Number.....................................913
NEUROTOXIC EFFECTS OF INTRANASAL
MANGANESE EXPOSURE AND
INTERACTION WITH CADMIUM
EXPOSURE IN A MOUSE MODEL. ​A. H.
Moberly, J. Pottackal, L. Czarnecki, T. Rubinstein, D.
J. Turkel and J. P. McGann. Psychology Department,
Rutgers University, Piscataway, NJ.
Abstract #
#2134 Poster Board Number.....................................914
MANGANESE AND VANADIUM EXPOSURE
INDUCES SEVERE NEUROTOXIC
RESPONSE IN OLFACTORY SYSTEM
OF AN ANIMAL MODEL: POTENTIAL
RELEVANCE TO OLFACTORY
DYSFUNCTION AND PARKINSON’S
DISEASE (PD). ​H. Afeseh Ngwa, A. Kanthasamy,
V. Anantharam and A. G. Kanthasamy. Iowa State
University, Ames, IA.
#2135 Poster Board Number.....................................915
CHRONIC MANGANESE ALTERS THYROID
AND ESTROGEN LEVELS IN RATS BLOOD. ​
O. Soldin 1 and M. Aschner 2 . 1 Departments of
Oncology, Medicine, Physiology and Biophysics,
Obstetrics and Gynegology, Georgetown University,
Washington, D.C. and 2 Departments of Pediatrics and
Pharmacology, Vanderbilt University, Nashville, TN.
#2136 Poster Board Number.....................................916
PEPTIDOME AND PROTEOME IN MURINE
CHOROID PLEXUS-CEREBROSPINAL
FLUID SYSTEM: EFFECT OF CHRONIC
MANGANESE (MN) EXPOSURE. ​G. J. Li 1 , K.
H. Wei 2 , H. M. Jing 1 , F. Yang 2 , C. Y. Zhao 1 , L. Ma 1 ,
T. Zhang 2 , X. Y. Zhang 2 , J. Z. Liu 1 , L. P. Liu 1 and W.
Zheng 3 . 1 Beijing Center for Preventive Medicine,
Beijing, China, 2 Beijing Proteome Research Center,
Beijing, China and 3 Purdue University, West
Lafayette, IN.
#2137 Poster Board Number.....................................917
REDUCED COPPER CLEARANCE BY THE
BLOOD-CSF BARRIER FOLLOWING IN
VIVO MANGANESE AND THE ROLE OF CU
TRANSPORTER ATP7A. ​X. Fu, Y. Zhang, W.
Jiang, A. D. Monnot and W. Zheng. School of Health
Sciences, Purdue University, West Lafayette, IN.
#2138 Poster Board Number.....................................918
INCREASED BETA-AMYLOID DEPOSITION
IN TRANSGENIC APP MICE FOLLOWING
CHRONIC LEAD (PB) EXPOSURE. ​W.
Zheng 1 , H. Gu 2 , X. Wei 2 , A. D. Monnot 1 and Y. Du 1,2 .
1
School of Health Sciences, Purdue University, West
Lafayette, IN and 2 Neurology, Indiana University
School of Medicine, Indianapolis, IN.
#2139 Poster Board Number.....................................919
NEUROIMAGING OF MANGANESE
TOXICITY: EFFECT OF EXPOSURE TIME
ON ACCUMULATION IN HUMAN BRAIN. ​J.
Xu 1,2 , X. Li 3 , S. Streitmatter 1 , L. Long 3 , W. Zheng 1 , Y.
Jiang 3 and U. Dydak 1,2 . 1 School of Health Sciences,
Purdue University, West Lafayette, IN, 2 Indiana
Univeristy School of Medicine, Indianapolis, IN and
3
Guangxi Medical University, Nanning, China.
#2140 Poster Board Number.....................................920
NEUROIMAGING OF MANGANESE
TOXICITY: GABA AND METABOLIC
CHANGES IN THE HUMAN BRAIN. ​Z.
Long 1,2 , Y. Jiang 3 , X. Li 3 , J. Xu 1,2 , L. Long 3 , W.
Zheng 1 and U. Dydak 1,2 . 1 School of Health Sciences,
Purdue University, West Lafayette, IN, 2 Indiana
University School of Medicine, Indianapolis, IN and
3
Guangxi Medical University, Nanning, China.
Wednesday
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