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50 th Anniversary Annual Meeting and ToxExpo Program Description (Continued) MONday Abstract # Abstract # #634 Poster Board Number.....................................528 IN VITRO EVALUATION OF THE EFFECT OF DOSE, RECEPTOR FLUID, AND VEHICLE ON THE ABSORPTION OF FIVE PHYSICOCHEMICALLY DIFFERENT COMPOUNDS IN PORCINE SKIN. D. Karadzovska, E. L. Koivisto, J. D. Brooks and J. E. Riviere. Center for Chemical Toxicology Research and Pharmacokinetics, North Carolina State University, Raleigh, NC. #635 Poster Board Number.....................................529 CHARACTERIZATION OF NORMAL SKIN THICKNESS FOR VARIOUS BODY REGIONS, AGES, AND GENDERS OF YUCATAN MINIATURE SWINE. L. Brown 1 , D. Kim 2 , C. Hanks 1 , D. Brocksmith 1 , M. Hodges 1 , J. Liu 1 and G. Bouchard 1 . 1 Sinclair Research Center, Columbia, MO and 2 VMDL CVM University of Missouri, Columbia, MO. #636 Poster Board Number.....................................530 NORMAL PHYSIOLOGICAL RANGES FOR HANFORD MINIATURE SWINE. M. Ross, L. Brown, D. Unterreiner, C. Hanks, J. Liu, M. Hodges and G. Bouchard. Sinclair Research Center, Columbia, MO. #637 Poster Board Number.....................................531 ROLE OF MAP KINASES IN REGULATING EXPRESSION OF KERATINOCYTE ANTIOXIDANTS BY THE ELECTROPHILIC NITRO-FATTY ACIDS DERIVATIVES 9- AND 10-NITROOLEIC ACID. R. Zheng 1 , A. T. Black 1 , A. Gow 1 , D. E. Heck 3 , D. L. Laskin 1 and J. D. Laskin 2 . 1 Rutgers University, Piscataway, NJ, 2 UMDNJ-Robert Wood Johnson Medical School, Piscataway, NJ and 3 New York Medical College, Valhalla, NY. #638 Poster Board Number.....................................532 A STUDY OF PHOTOTOXICITY FOLLOWING INTRAVENOUS ADMINISTRATION OF CIPROFLOXACIN HYDROCHLORIDE IN THE MICROMINIPIG. H. Kawaguchi 1 , N. Miyoshi 1 , A. Tanimoto 1 , Y. Takahashi 2 , S. Utsunomiya 2 , T. Motokado 2 , Y. Ooshima 2 , H. Izumi 2 , T. Sukamoto 2 and R. Nagata 2 . 1 Kagoshima University, Kagoshima, Japan and 2 Shin Nippon Biomedical Laboratories (SNBL), Ltd., Kagoshima, Japan. #639 Poster Board Number.....................................533 INFLUENCE OF THE ARYL HYDROCARBON RECEPTOR ON PROLIFERATION OF HUMAN KERATINOCYTES (HACAT). M. Kalmes, J. Hennen, J. Clemens and B. Blömeke. Environmental Toxicology, University of Trier, Trier, Germany. #640 Poster Board Number.....................................534 WHAT IS THE BEST SKIN PREPARATION FOR DERMAL PENETRATION STUDIES IN VITRO? A COMPARISON OF FULL- THICKNESS SKIN AND DERMATOMED SKIN. K. Guth 1 , M. Schaefer-Korting 2 , E. Fabian 1 , B. van Ravenzwaay 1 and R. Landsiedel 1 . 1 BASF SE, Experimental Toxicology and Ecology, Ludwigshafen, Germany and 2 Freie Universitaet, Berlin, Germany. #641 Poster Board Number.....................................535 ANTI-INFLAMMATORY DRUG EFFICACY FOR TREATING SULFUR MUSTARD INDUCED CUTANEOUS LESIONS. J. L. Plahovinsak 1 , M. D. Etheridge 1 , J. Rhone 1 , F. M. Reid 1 , J. F. Dillman 2 and J. S. Graham 2 . 1 Battelle, Columbus, OH and 2 U.S. Army Medical Research Institute of Chemical Defense, Aberdeen, MD. #642 Poster Board Number.....................................536 DERMAL ABSORPTION OF DICYCLOHEXYLAMINE (DCHA) IN METAL WORKING FLUID FORMULATIONS. R. Baynes, A. Linthicum, J. Yeatts, J. Brooks and E. Koivisto. North Carolina State University, Raleigh, NC. #643 Poster Board Number.....................................537 INTERLEUKIN 6 EXPRESSION MODULATES IRRITANT DERMATITIS SEVERITY. E. G. Lee, B. M. Mickle and R. Gallucci. Pharmaceutical Sciences, Oklahoma University State Health Sciences Center College of Pharmacy, Oklahoma City, OK. #644 Poster Board Number.....................................538 THE EPIOCULAR ASSAY FOR TESTING EYE IRRITATION IN VITRO: IN HOUSE VALIDATION WITH 60 TEST SUBSTANCE IN A ROUTINE LAB OF THE CHEMICAL INDUSTRY. A. Schrage 1 , S. Kolle 1 , B. Wareing 1 , R. B. Tacou 1,2 , B. van Ravenzwaay 1 , H. Kanderova 3 and R. Landsiedel 1 . 1 Experimental Toxicology and Ecology, BASF SE, Ludwigshafen am Rhein, Germany, 2 Master Program in Toxicology, Technical University of Kaiserslautern, Kaiserslautern, Germany and 3 MatTek Corporation, Ashland, MA. #645 Poster Board Number.....................................539 EVALUATION OF THE IN VITRO EPISKIN AND SKINETHIC RHE SKIN IRRITATION TEST METHODS FOR HAZARD IDENTIFICATION OF CHEMICALS. D. Lelièvre 1 , N. Alépée 1 , J. Cotovio 1 , M. H. Grandidier 1 , A. De Brugerolle de Fraissinette 2 , C. Tornier 2 and J. R. Meunier 1 . 1 L’Oréal, Aulnay sous Bois, France and 2 SkinEthic Laboratories, Lyon, France. Sponsor: H. Toutain. #646 Poster Board Number.....................................540 ADAPTATION OF THE VALIDATED SKINETHIC RHE SKIN CORROSION TEST METHOD TO 0.5 CM2 TISSUE SAMPLE. C. Tornier 1 , M. Roquet 1 , N. Alépée 2 , J. R. Meunier 2 and A. De Brugerolle de Fraissinette 1 . 1 SkinEthic Laboratories, Lyon, France and 2 L’Oréal, Aulnay sous Bois, France. Sponsor: H. Toutain. #647 Poster Board Number.....................................541 EXPRESSION AND INDUCTION OF XENOBIOTIC METABOLISM GENES IN THE STRATATEST® HUMAN SKIN MODEL. C. Rasmussen, K. Gratz, N. Simon, M. VanderZanden, C. Johnston and L. Allen-Hoffmann. Stratatech Corporation, Madison, WI. 170 Education-Career Development Sessions Exhibitor Hosted Sessions Featured Sessions Historical Highlights Informational Sessions Platform Sessions
Society of Toxicology 2011 Program Description (Continued) Abstract # #648 Poster Board Number.....................................542 INTRAMUSCULAR INJECTION SITES: IS THE QUALITY OF THE DIAGNOSIS IMPROVED WHEN MORE THAN ONE TISSUE SECTION IS EXAMINED? C. Thuilliez, M. Perron-Lepage, C. Clément, J. Briffaux and C. Botteron. Ricerca Biosciences SAS, Lyon, France. Monday Afternoon, March 7 1:00 PM to 4:30 PM Exhibit Hall Poster Session: Immunotoxicity: Methods and Evaluation Chairperson(s): Raj Krishnaraj, Covance Inc., Madison, WI. Displayed: 1:00 PM–4:30 PM Author Attended: 1:00 PM–2:45 PM #649 Poster Board Number.....................................547 ESTABLISHMENT OF T-CELL INDEPENDENT ANTIBODY RESPONSE IN RATS AS AN IMMUNOTOXICITY EVALUATION METHOD. S. Ito, H. Hattori, R. Kawai, S. Komatsu, K. Muramatsu, M. Yagi, T. Matsuyama, T. Furukawa and A. Sanbuissho. Medicinal Safety Research Laboratories, Daiichi Sankyo Co., LTD., Fukuroi, Shizuoka, Japan. Sponsor: M. Teranishi. #650 Poster Board Number.....................................548 ANALYTICAL VALIDATION OF IMMUNOPHENOTYPING FOR CD5 IN PERIPHERAL BLOOD, SPLEEN, AND THYMUS FOR CD 1 MICE. P. Sims 2 , P. Joshi 2 , J. E. Arrington 1 and J. Puchalski 2 . 1 Toxicology Study Direction, Covance, Madison, WI and 2 Immunotoxicology, Covance, Madison, WI. #651 Poster Board Number.....................................601 ANALYTICAL VALIDATION OF SPLEEN, THYMUS, AND MESENTERIC AND MANDIBULAR LYMPH NODE IMMUNOPHENOTYPING FOR SPRAGUE- DAWLEY RATS. J. E. Arrington and P. Joshi. Immunotoxicology, Covance, Madison, WI. #652 Poster Board Number.....................................602 IN VITRO MODEL FOR IMMUNOTOXICITY: SURFACE MARKER EXPRESSION AND CYTOKINE RELEASE IN NORMAL HUMAN DENDRITIC CELLS. T. Landry, M. Klausner, A. Hunter, J. Sheasgreen, P. J. Hayden and S. Ayehunie. MatTek Corp, Ashland, MA. #653 Poster Board Number.....................................603 USE OF AN ELECTROSPUN POLYCAPROLACTONE NANOFIBROUS SCAFFOLD AS A POTENTIAL DRUG DELIVERY SYSTEM FOR IMMUNOMODULATORY COMPOUNDS. C. E. McLoughlin, M. J. Smith, W. Auttachoat, G. L. Bowlin and K. L. White. Virginia Commonwealth University, Richmond, VA. Abstract # #654 Poster Board Number.....................................604 TCDD ADSORBED ONTO NATURAL AND SYNTHETIC SILICA SUPPRESSES HUMORAL IMMUNITY IN MICE. N. Kovalova 1,2 , R. Crawford 2 , B. Kaplan 2 , S. Kim 3 , S. Boyd 3 , B. Teppen 3 , C. Johnston 5 , T. Pinnavaia 4 and N. Kaminski 1,2 . 1 Pharmacology & Toxicology, Michigan State University, East Lansing, MI, 2 Center for Integrative Toxicology, Michigan State University, East Lansing, MI, 3 Crop & Soil Science, Michigan State University, East Lansing, MI, 4 Chemistry, Michigan State University, East Lansing, MI and 5 Soil Chemistry & Mineralogy, Purdue University, W. Lafayette, IN. #655 Poster Board Number.....................................605 TITANIUM DIOXIDE NANOPARTICLES: LACK OF IMMUNOSUPRESSIVE AND CONTACT HYPERSENSITIVITY EFFECTS IN FEMALE MICE. W. Auttachoat 1 , C. E. McLoughlin 2 , M. J. Smith 1 and K. L. White 1 . 1 Pharmacology & Toxicology, Virginia Commonwealth University, Richmond, VA and 2 Biomedical Engineering, Virginia Commonwealth University, Richmond, VA. #656 Poster Board Number.....................................606 ACTIVATED CYTOTOXIC AND HELPER T-CELLS ARE REDUCED IN C57BL6 MICE EXPOSED TO TUNGSTATE IN A ONE- GENERATION EXPOSURE. A. R. Osterburg 1 , C. T. Robinson 2 , V. P. Mokashi 1 , M. G. Stockelman 1 and G. F. Babcock 2 . 1 Naval Medical Research Unit - Dayton, Wright-Patterson AFB, OH and 2 Shriners Hospitals for Children and the University of Cincinnati, Cincinnati, OH. Sponsor: K. Mumy. #657 Poster Board Number.....................................607 ASSOCIATIONS OF PERFLUOROCHEMICALS (PFCS) WITH IMMUNE, BIOCHEMICAL, AND HEMATOLOGICAL PARAMETERS IN BOTTLENOSE DOLPHINS. P. Fair 1 , T. Romano 2 , T. Hulsey 3 , J. Reif 4 , G. Bossart 5 , J. Adams 1 , M. Houde 6 , D. Muir 6 , C. Rice 7 and P. Margie 8 . 1 NOAA/NOS, Charleston, SC, 2 Mystic Aquarium, Mystic, CT, 3 Medical University of South Carolina, Charleston, SC, 4 Colorado State University, Fort Collins, Co., 5 Harbor Branch Oceanographic Institute at Florida Atlantic University, Fort Pierce, FL, 6 Environment Canada, Burlington, ON, Canada, 7 Clemson University, Clemson, SC and 8 University of Nevada Las Vegas, Las Vegas, NV. #658 Poster Board Number.....................................608 COMPARISON EFFECTS OF IN VITRO PFOS EXPOSURE ON BOTTLENOSE DOLPHIN AND MURINE IMMUNE FUNCTION. J. R. Wirth 1 , M. M. Peden-Adams 2 , N. Henry 3 and P. A. Fair 3 . 1 Graduate Program of Marine Biology, College of Charleston, Charleston, SC, 2 Harry Reid Center for Environmental Science, University of Nevada Las Vegas, Las Vegas, NV and 3 NOAA/NOS/ CCEBHR, Charleston, SC. MONday Poster Sessions Regional Interest Session Roundtable Sessions Symposium Sessions Thematic Sessions Workshop Sessions 171
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50 th Anniversary Annual Meeting &
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Scientific Program Overview A page
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9:00 AM-12:30 PM POSTER SESSionS
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March 6-10, 2011 Walter E. Washingt
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Celebration Activities Historical H
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of the Society Regional Chapter Yea
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SOT Presidents 1961-2011 1966 1967
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The SOT Council Thanks and Recogniz
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of the Past 50 Years 2003 Michael D
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Toxicological Sciences The Official
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Society of Toxicology 2011 ToxExpo
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SOT Job Bank YOUR RECRUITMENT AND E
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Society of Toxicology 2011 SOT 2011
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Society of Toxicology 2011 Author I
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Society of Toxicology 2011 2010-201
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