Program - Society of Toxicology

50 th Anniversary Annual Meeting and ToxExpo
Program Description (Continued)
Tuesday
Abstract # Abstract #
#1009 Poster Board Number.....................................236
THE KERATINOSENS ASSAY TO
DETECT SKIN SENSITIZERS BASED ON
NRF2-DEPENDENT GENE ACTIVITY:
EXPLORING THE INTER-LABORATORY
REPRODUCIBILITY AND THE
APPLICABILITY DOMAIN. ​A. Natsch 1 , C.
Bauch 2 , G. Ellis 1 , L. Foertsch 4 , F. Gerberick 4 , K.
Norman 3 , R. Landsiedel 2 , S. Onken 5 , H. Reuter 5 , A.
Schepky 5 and R. Emter 1 . 1 Givaudan Schweiz AG,
Duebendorf, Switzerland, 2 BASF SE, Ludwigshafen,
Germany, 3 The Institute for In Vitro Sciences, Inc.
(IIVS), Gaithersburg, MD, 4 Procter & Gamble Inc.,
Cincinnati, OH and 5 Beiersdorf AG, Hamburg,
Germany.
#1010 Poster Board Number.....................................237
THE MYELOID U937 SKIN SENSITIZATION
TEST (MUSST) FOR THE PREDICTION
OF SKIN SENSITIZATION POTENTIAL. ​
J. Ovigne, C. Piroird, D. Verda, F. Rousset, S.
Martinozzi-Teissier and J. Meunier. L’Oréal
Research, Aulnay-sous-Bois, France. Sponsor: H.
Toutain.
#1011 Poster Board Number.....................................238
IN VITRO GENE EXPRESSION PROFILING
TO PREDICT SKIN SENSITIZING
POTENTIAL. ​J. van der Veen 1,2 , J. Ezendam 1 ,
T. Pronk 1,2 , R. Vandebriel 1 , J. Pennings 1 and H.
van Loveren 1,2 . 1 Laboratory for Health Protection
Research, National Institute for Public Health
and the Environment, Bilthoven, Netherlands and
2
Department of Health Risk Analysis and Toxicology,
Maastricht University, Maastricht, Netherlands.
#1012 Poster Board Number.....................................239
COMPARATIVE INVESTIGATION OF
PHOTOTOXICITY OF CHEMICAL
COMPOUNDS BY USING THE STANDARD
BALB 3T3 NRU PHOTOTOXICITY TEST
AND A THREE-DIMENSIONAL HUMAN
SKIN MODEL (EST 1000). ​A. Heppenheimer
and A. H. Poth. Genetic and Alternative Toxicology,
Harlan Cytotest Cell Research GmbH, Rossdorf,
Germany.
#1013 Poster Board Number.....................................240
FUNCTIONAL IN VITRO ASSAYS
OF DIFFERENT CELL SOURCES
ARE ABLE TO PREDICT SPECIFIC
IMMUNOSUPPRESSIVE PROPERTIES OF
CHEMICAL COMPOUNDS. ​A. Fischer, L.
Koeper and H. Vohr. Toxicology, Bayer Schering
Pharmacology Wuppertal, Germany. Sponsor: H.
Ellinger-Ziegelbauer.
#1014 Poster Board Number.....................................241
PRECISION-CUT LIVER SLICES AS AN EX
VIVO MODEL TO STUDY IDIOSYNCRATIC
HEPATOTOXICITY IN MOUSE AND
HUMAN. ​M. Hadi 1 , Y. Chen 1 , M. Stitzinger 2 , H.
Emmen 2 and G. Groothuis 1 . 1 Pharmacokinetics,
Toxicology & Targeting, University of Groningen,
Groningen, Netherlands and 2 Toxicology, NOTOX
BV, s’-Hertogenbosch, Netherlands. Sponsor: A.
Vickers.
#1015 Poster Board Number.....................................242
TRANSPORT OF CHLORPROMAZINE
ACROSS CACO-2 CELLS AND MEASURING
THE FREE CONCENTRATION BY ND-SPME. ​
J. Broeders, B. Blaauboer and J. Hermens. Institute
for Risk Assessment Sciences, Utrecht University,
Utrecht, Netherlands.
#1016 Poster Board Number.....................................243
INTERNATIONAL VALIDATION STUDY
OF AN IN VITRO CELL PROLIFERATION
TEST METHOD FOR SCREENING
POTENTIAL ESTROGENIC AGONISTS
AND ANTAGONISTS IN MCF-7 CELLS. ​F.
Deal 2 , W. Casey 1 , P. Ceger 2 , D. Allen 2 , C. Yang 3 ,
M. Nakamura 4 , H. Kojima 5 , A. Ono 5 , H. Yoon 6 ,
S. Han 7 and W. Stokes 1 . 1 NICEATM, NIEHS,
Research Triangle Park, NC, 2 ILS, Inc., Research
Triangle Park, NC, 3 CertiChem Inc., Austin, TX,
4
Hiyoshi Corp., Omihachiman, Japan, 5 JaCVAM,
Tokyo, Japan, 6 NIFDS, KFDA, Seoul, Democratic
People’s Republic of Korea and 7 KoCVAM, Seoul,
Democratic People’s Republic of Korea.
#1017 Poster Board Number.....................................244
FINAL RESULTS OF AN INTERNATIONAL
VALIDATION STUDY OF AN IN VITRO ER
TA TEST METHOD IN BG-1 CELLS. ​W.
Casey 1 , P. Ceger 2 , D. Allen 2 , G. Clark 3 , P. Pazos 4 , E.
Grignard 4 , J. de Lange 4 , S. Bremer 4 , M. Nakamura 5 ,
H. Kojima 6 and W. Stokes 1 . 1 NICEATM, NIEHS,
Research Triangle Park, NC, 2 ILS, Inc., Research
Triangle Park, NC, 3 XDS, Inc., Durham, NC,
4
ECVAM, Ispra, Italy, 5 Hiyoshi Corp., Omihachiman,
Japan and 6 JaCVAM, Tokyo, Japan.
#1018 Poster Board Number.....................................245
AFLATOXIN B 1
INDUCED DNA DAMAGE
IN TURKEY AND CHICKEN EGG FOETAL
LIVER CELLS. ​J. G. Williams 1 , U. Deschl 2 and
G. M. Williams 1 . 1 Department of Pathology, New
York Medical College, Valhalla, NY and 2 Boehringer
Ingelheim Pharmacology KG, Boehringer Ingelheim
Pharmacology KG, Biberach/Riss, Germany.
#1019 Poster Board Number.....................................246
TRACE METALS ALTER HISTONE
METHYLATION PATHWAYS IN MOUSE
EMBRYONIC STEM CELLS. ​S. R. Gadhia and
F. A. Barile. Pharmaceutical Sciences, St. John’s
University College of Pharmacy, Queens, NY.
#1020 Poster Board Number.....................................247
MICRO ELECTRODE CHIP ASSAY (MEA) AS
METHOD TO DETECT NEUROTOXICITY
IN VITRO. ​S. Vogel 1 , A. Novellino 2 , E. De
Franchi 2 , B. van Ravenzwaay 1 and R. Landsiedel 1 .
1
BASF SE, Experimental Toxicology and Ecology,
Ludwigshafen, Germany and 2 ETTs.r.l, Genova, Italy.
#1021 Poster Board Number.....................................248
EFFECT OF METALS ON β-ACTIN
AND TOTAL PROTEIN SYNTHESIS
IN CULTURED HUMAN INTESTINAL
EPITHELIAL CELLS. ​A. R. Calabro and F.
A. Barile. Pharmaceutical Sciences, St. John’s
University College of Pharmacy, Queens, NY.
206
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