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50 th Anniversary Annual Meeting and ToxExpo Program Description (Continued) Wednesday Abstract # Abstract # #2092 Poster Board Number.....................................807 PESTICIDE MIXTURES IN REPTILIAN AND AQUATIC MODELS. M. H. Feld and I. P. Callard. Department of Biology, Boston University, Boston, MA. #2093 Poster Board Number.....................................808 JOINT TOXICITY OF PERMETHRIN AND ATRAZINE TO ZEBRAFISH (DANIO RERIO). P. Wages, A. Trimble and M. Posner. Biology/ Toxicology, Ashland University, Ashland, OH. Sponsor: P. Wages. #2094 Poster Board Number.....................................809 2, 4-DICHLOROPHENOXYACETIC ACID (2, 4-D): EVALUATION OF ENDOCRINE MODULATING POTENTIAL. B. Neal 1 , M. S. Marty 2 , K. Coady 2 and J. C. Lamb 1 . 1 Center for Toxicology and Mechanistic Biology, Exponent, Alexandria, VA and 2 Toxicology & Environmental Research and Consulting, Dow Chemical Company, Midland, MI. #2095 Poster Board Number.....................................810 LATE FETAL RESORPTIONS IN RATS INDUCED BY EPOXICONAZOLE OCCUR IN THE PRESENCE OF SIGNIFICANT MATERNAL TOXICITY AND CAN BE ANTAGONIZED BY ESTRADIOL CO-TREATMENT. S. Stinchcombe 1 , S. Schneider 2 , I. Fegert 1 , V. Strauss 2 , S. Gröters 2 , M. C. Rey Moreno 2 and B. van Ravenzwaay 2 . 1 Regulatory Toxicology Pesticides, BASF SE, Ludwigshafen, Germany and 2 Experimental Toxicology and Ecology, BASF SE, Ludwigshafen, Germany. Sponsor: R. Parod. #2096 Poster Board Number.....................................811 MICROARRAY ANALYSIS OF GENE EXPRESSION CHANGES IN HUMAN HEPATOCYTES AFTER CHLORPYRIFOS EXPOSURE. A. D. Wallace 1 , R. Shah 2 , K. Choi 1 , H. Joo 1 and E. Hodgson 1 . 1 Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC and 2 Sciome LLC, Research Triangle Park, NC. #2097 Poster Board Number.....................................812 HUMAN HEPATIC CYTOCHROME P450-SPECIFIC METABOLISM OF CHLORPYRIFOS, PARATHION, METHYL PARATHION, AND DIAZINON. Y. Tian, C. A. Ellison, R. J. Foxenberg, B. P. McGarrigle, J. B. Knaak and J. R. Olson. Pharmacology and Toxicology, University at Buffalo, Buffalo, NY. #2098 Poster Board Number.....................................813 STUDY OF THE INHIBITION OF RECOMBINANT HUMAN CARBOXYLESTERASE 1 AND 2 BY CHLORPYRIFOS OXON, PARAOXON, AND METHYL PARAOXON. J. A. Crow 1 , V. Bittles 1 , K. Herring 1 , A. Borazjani 1 , P. M. Potter 2 and M. K. Ross 1 . 1 Mississippi State University, Mississippi State, MS and 2 St. Jude Children’s Hospital, Memphis, TN. #2099 Poster Board Number.....................................814 GLOBAL TRANSCRIPTIONAL PROFILE OF DICHLORVOS EFFECTS IN DANIO RERIO. T. M. Bui Nguyen 1,2 , N. Hussainzada 1,2 , C. Baer 3 , J. Lewis 2 and D. Jackson 2 . 1 Oak Ridge Institute for Science and Education-U.S. Army Center for Environmental Health Research, Fort Detrick, MD, 2 U.S. Army Center for Environmental Health Research-Fort Detrick, Fort Detrick, MD and 3 Excet, Inc., Fort Detrick, MD. #2100 Poster Board Number.....................................815 ABSORPTION AND LIMITED PHARMACOKINETICS OF INHALED SULFURYL FLUORIDE IN NEW ZEALAND WHITE RABBITS. D. L. Eisenbrandt 1 , M. J. Bartels 2 , S. M. Krieger 2 , D. A. Markham 2 , D. L. Rick 2 and J. A. Hotchkiss 2 . 1 Dow AgroSciences, LLC, Indianapolis, IN and 2 The Dow Chemical Company, Midland, MI. #2101 Poster Board Number.....................................816 KINETIC INTERACTION OF SOLUBLE ESTERASES OF BRAIN AND PHENYLMETHYLSULPHONYL FLUORIDE (PMSF), AN INHIBITOR PROTECTING AND POTENTIATING THE ORGANOPHOSPHORUS DELAYED NEUROTOXICITY. E. Vilanova, I. Mangas and J. Estévez. Instituto de Bioingeniería, Universidad Miguel Hernández, Elche, Alicante, Spain. #2102 Poster Board Number.....................................817 IMPACTS OF HYPERSALINE CONDITIONS ON ORGANOPHOSPHATE TOXICITY. L. A. Maryoung, R. Lavado and D. Schlenk. Environmental Toxicology, University of California, Riverside, Riverside, CA. #2103 Poster Board Number.....................................818 METABOLISM OF CHLORPYRIFOS BY ALLELIC ISOFORMS OF CYP2B6, A KEY BIOACTIVATING ENZYME. A. L. Crane, B. P. McGarrigle and J. R. Olson. Pharmacology and Toxicology, University at Buffalo, Buffalo, NY. #2104 Poster Board Number.....................................819 ALTERATIONS IN THE EXPRESSION OF PYRETHROID PESTICIDE METABOLIZING ENZYMES DURING GESTATION IN MICE. M. C. Fortin 1 , L. M. Aleksunes 2 and J. R. Richardson 1 . 1 Environmental and Occupational Medicine, Environmental and Occupational Health Sciences Institute, Piscataway, NJ and 2 Pharmacology and Toxicology, Rutgers University, Piscataway, NJ. #2105 Poster Board Number.....................................820 ACUTE INHALATION OF AEROSOLIZED CHLORPYRIFOS BY ADULT SPRAGUE- DAWLEY RATS: ABSORPTION, METABOLISM, AND KINETICS OF CHOLINESTERASE INHIBITION IN RED BLOOD CELLS, PLASMA, BRAIN, AND LUNG. J. A. Hotchkiss 1 , S. M. Krieger 1 , D. L. Rick 1 , M. J. Bartels 1 , F. B. Selman 2 and D. R. Juberg 2 . 1 The Dow Chemical Company, Midland, MI and 2 Dow AgroSciences, LLC, Indianapolis, IN. 300 Education-Career Development Sessions Exhibitor Hosted Sessions Featured Sessions Historical Highlights Informational Sessions Platform Sessions
Society of Toxicology 2011 Program Description (Continued) Abstract # #2106 Poster Board Number.....................................821 CONSTRUCTION AND VALIDATION OF A HUMAN PBPK/PD MODEL FOR DERMAL CHLORPYRIFOS EXPOSURE UTILIZING HUMAN BIOMARKER DATA. C. A. Ellison 1 , J. B. Knaak 1 , R. McDougall 2 , P. J. Lein 3,4 , F. M. Farahat 5 , K. Anger 3 and J. R. Olson 1 . 1 University at Buffalo, Buffalo, NY, 2 University of Ontario Institute of Technology, Oshawa, ON, Canada, 3 Oregon Health & Science University, Portland, OR, 4 University of California Davis School of Veterinary Medicine, Davis, CA and 5 Menoufia University, Shibin el Kom, Egypt. #2107 Poster Board Number.....................................822 INTEGRATION OF TOXICOKINETICS (TK) INTO GUIDELINE TOXICITY STUDIES OF A NEW AGROCHEMICAL. S. A. Saghir 1 , D. L. Rick 1 , A. J. Clark 1 , J. L. Staley 1 , M. J. Bartels 1 , C. Terry 2 and R. Billington 2 . 1 The Dow Chemical Co., Midland, MI and 2 Dow AgroSciences, Milton Park, United Kingdom. #2108 Poster Board Number.....................................823 TOXICOKINETIC - TOXICODYNAMIC RELATIONSHIPS IN CASES OF GLYPHOSATE HERBICIDE EXPOSITION. A. Anadon, M. A. Martínez, I. Ares, E. Ramos, V. Castellano, M. Martínez and M. R. Martínez- Larrañaga. Department of Toxicology and Pharmacology, Faculty of Veterinary Medicine, Universidad Complutense, Madrid, Spain. #2109 Poster Board Number.....................................824 PROPICONAZOLE INDUCES ALTERATIONS IN THE HEPATIC METABOLOME OF MICE: RELEVANCE TO PROPICONAZOLE- INDUCED HEPATOCARCINOGENESIS. S. Nesnow, T. Moore and W. Padgett. NHEERL/ISTD, U.S. EPA, Research Triangle Park, NC. Sponsor: S. Hester. #2110 Poster Board Number.....................................825 EXPRESSION OF CYPS 2B1/2B2, BUT NOT CYPS 1A1 OR 1A2, ARE INDUCED IN THE LIVER FROM RATS FED MIXTURES OF THE PESTICIDES DIELDRIN, DICHLORVOS, PERMETHRIN, DICOFOL, AND ENDOSULFAN. S. Ramos da Silva, C. S. Franchi, J. V. de Camargo and D. Elgui de Oliveira. Pathology, São Paulo State University (UNESP) Medical School, Botucatu, SP, Brazil. Sponsor: D. Wolf. #2111 Poster Board Number.....................................826 CYTOCHROME P450 3A5 GENOTYPE IS CORRELATED WITH ACETYLCHOLINESTERASE INHIBITION LEVELS AFTER EXPOSURE TO ORGANOPHOSPHATE PESTICIDES. Z. Guerrette 1 , E. G. Moreira 1,3 , W. C. Griffith 1 , G. D. Coronado 2 , E. M. Vigoren 1 , X. Yu 1 , B. Thompson 1,2 and E. M. Faustman 1 . 1 Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, 2 Fred Hutchinson Cancer Research Center, Seattle, WA and 3 State University of Londrina, Londrina, PR, Brazil. Abstract # #2112 Poster Board Number.....................................827 GLUTATHIONE S-TRANSFERASE POLYMORPHISMS INFLUENCE THE LEVEL OF OXIDATIVE DNA DAMAGE IN SOYBEAN PESTICIDE APPLICATORS. M. A. Carballo 1 , M. Porcel de Peralta 2 , E. Kleinsorge 2 and M. Simoniello 1,2 . 1 Bioquímica Clínica, Facultad de Farmacia y Bioquímica. Universidad de Buenos Aires, Buenos Aires, Argentina and 2 Bioquimica Clínica, CIGETOX. INFIBIOC. Facultad de Farmacia y Bioquímica. UBA, Buenos Aires, Argentina. Sponsor: O. Olivero. #2113 Poster Board Number.....................................828 HYDROLYSIS OF ORGANOPHOSPHATE AND MODEL SUBSTRATES IN AFRICAN AMERICAN AND CAUCASIAN SOUTHERNERS BY SERUM PARAOXONASE-1 (PON1) AND RELATIONSHIP TO ATHEROSCLEROSIS. H. Coombes, A. Crow, M. Dail, H. Chambers, R. Wills, E. Meek and J. Chambers. Mississippi State University, Mississippi State, MS. #2114 Poster Board Number.....................................829 INTRAVENTRICULAR CONDUCTION DELAY AFTER GLYPHOSATE- SURFACTANT HERBICIDES INTOXICATION. Y. Tseng 1 , C. Chen 1,2 , C. Huang 4 , W. Chen 1 and D. Hung 1,2,3 . 1 Department of Emergency, China Medical University Hospital, Taichung, Taiwan, 2 Toxicology Center, China Medical University Hospital, Taichung, Taiwan, 3 Graduate Institute of Drug Safety, College of Pharmacy, China Medical University, Taichung, Taiwan and 4 School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan. #2115 Poster Board Number.....................................830 GENETIC DAMAGE AND GENE EXPRESSION IN PESTICIDE RETAILERS FROM NAYARIT, MEXICO. E. Rojas 1 , S. Lara-Montoya 1 , P. Ostrosky 2 , M. Sordo 2 , M. Medina- Díaz 1 , L. Robledo-Marenco 1 , A. Benitez-Trinidad 1 , B. Quintanilla-Vega 3 and M. Bermúdez de León 4 . 1 Laboratorio de Contaminación y Toxicología Ambiental, Universidad Autónoma de Nayarit, Tepic, Nayarit, Mexico, 2 Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico, D.F., D.F., Mexico, 3 Departamento de Toxicología, Centro de Investigación y de Estudios Avanzados del IPN, Mexico, D.F., D.F., Mexico and 4 Laboratorio de Biología Molecular, Centro de Investigación Biomédica del Noreste- IMSS, Monterrey, Nuevo León, Mexico. Wednesday Poster Sessions Regional Interest Session Roundtable Sessions Symposium Sessions Thematic Sessions Workshop Sessions 301
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50 th Anniversary Annual Meeting &
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Scientific Program Overview A page
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9:00 AM-12:30 PM POSTER SESSionS
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March 6-10, 2011 Walter E. Washingt
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Celebration Activities Historical H
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of the Society Regional Chapter Yea
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SOT Presidents 1961-2011 1966 1967
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The SOT Council Thanks and Recogniz
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of the Past 50 Years 2003 Michael D
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Thank You to the following individu
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50 th Anniversary Annual Meeting an
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Toxicological Sciences The Official
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Society of Toxicology 2011 Walter E
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Society of Toxicology 2011 Washingt
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2011 SOT 50 th Anniversary Featured
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Society of Toxicology 2011 Washingt
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Society of Toxicology 2011 ToxExpo
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Society of Toxicology 2011 Exhibito
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Creating a Safer and Healthier Worl
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Society of Toxicology 2011 General
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SOT Job Bank YOUR RECRUITMENT AND E
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Society of Toxicology 2011 SOT 2011
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Society of Toxicology 2011 2011 Awa
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Society of Toxicology 2011 SOT Endo
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Society of Toxicology 2011 Recognit
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Society of Toxicology 2011 Recognit
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Society of Toxicology 2011 RC, SIG,
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Society of Toxicology 2011 Student
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Society of Toxicology 2011 Outreach
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Society of Toxicology 2011 Author I
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Society of Toxicology 2011 2010-201
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Society of Toxicology 2011 Elected
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Society of Toxicology 2011 Elected
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Society of Toxicology 2011 SOT Affi
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