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50 th Anniversary Annual Meeting and ToxExpo Abstract Key Word Index (Continued) The numerals following each key word refer to the relevant abstract number(s). Key Word Index nanoparticle size............................. 2067 Nanoparticle toxicity.... 847, 1472, 1801 nanoparticles.................... 56, 994, 1180, 1183, 1185, 1189, 1191, 1197, 1233, 1459, 1463, 1478, 1483, 1489, 1493, 1757, 1799, 2051, 2055, 2062, 2076, 2078, 2162, 2164, 2171, 2172, 2176, 2184, 2479 nano-particles................................. 1466 nanosilica........................................ 2084 nanosilver................... 1476, 1482, 1757 nano-silver........................................ 994 nano-specific controls..................... 2158 Nanotechnology................................ 848 Nanotoxicity.... 1455, 1486, 1488, 1757, 2073, 2171, 2172, 2182 nanotoxicity testing........................ 2158 Nanotoxicology................... 60, 61, 846, 849, 850, 1186, 1456, 1465, 1468, 1479, 1481, 1484, 1487, 1492, 1494, 1600, 1759, 1760, 1764, 1802, 1803, 1901, 2056, 2060, 2068, 2069, 2070, 2157, 2160, 2166, 2167, 2181, 2183 Nanotubes....................................... 1192 Naphthalene............. 240, 243, 580, 582, 887, 888, 1236, 1421, 1422, 1679, 1832, 1849, 1953, 1954, 1955, 1956, 1957 NAPQI.............................................. 458 nasal.................................................. 580 nasal carcinogenesis....................... 1953 Nasal toxicity.......................... 513, 1954 NASH............................................. 1108 NAT1.............................................. 1863 Natriuretic peptides.......................... 202 natural killer cells........................... 1142 natural product................................ 2428 Natural Products........... 479, 2220, 2222 natural sweetener............................ 2421 nausea............................................... 148 NCBC............................................... 285 NCL2................................................ 801 nd-SPME........................................ 1015 nebulizer........................................... 584 Neonatal................................ 2588, 2599 neonatal/prepubertal exposure.......... 618 Neonate rats...................................... 746 Neoplastic transformation.............. 1182 neopterin......................................... 2650 nephropathy...................................... 250 Nephrotoxicity......... 549, 738, 740, 743, 755, 763, 766, 1438, 1587, 1746, 2005 Nephrotoxicity, Metals..................... 773 nerve agent........ 2015, 2016, 2025, 2585 nervous system............................... 1020 Network............................................ 127 network analysis............................. 1738 neural development........................ 1340 Neural Differentiation......................... 79 Neural Stem Cell........ 1390, 2520, 2622 neurite outgrowth.............................. 870 Neurobehavior........................ 862, 2647 neurobehavioral changes..... 1379, 1380, 2401 neurobehavioral toxicity......... 174, 2626 neurobehavioral toxicology.............. 897 Neurodegeneration.................. 164, 179, 182, 842, 844, 845, 1396, 1397, 1401, 2128, 2455 Neurodegenerative diseases.... 172, 1331 Neurodevelopment............... 1772, 2144 neurodevelopmental......................... 620 neurodevelopmental toxicity........... 868, 2360 Neuroendocrine.............................. 1064 neurogenesis..... 1375, 1388, 1389, 2401 Neuroimaging................................. 2592 Neuroinflammation................... 178, 180 neuron............................................. 1354 neuronal.......................................... 1358 neuronal cell culture............. 2510, 2619 Neuronal cells................................. 1333 neuronal damage............................. 2037 neuronal differentiation........ 2518, 2622 Neuronal Injury.............................. 2619 Neuronal migration............... 1386, 1387 Neuropathy Target Esterase.............. 979 neurophysiology........ 1354, 1379, 1380, 1382, 2133 Neuroprogenitor cell......................... 867 neuroprotectants............................. 2014 neuroprotection............. 161, 2049, 2585 Neurotoxic Metals................ 1381, 2134 neurotoxicity............ 173, 176, 178, 527, 626, 629, 1220, 1226, 1227, 1306, 1330, 1334, 1339, 1346, 1351, 1376, 1388, 1389, 1393, 1397, 1398, 1399, 1443, 1444, 1464, 1805, 1829, 2018, 2055, 2101, 2108, 2141, 2142, 2148, 2182, 2243, 2458, 2461, 2576, 2608, 2611, 2612, 2627, 2664 neurotoxicity, pesticides................. 1207 Neurotoxicology.............. 77, 175, 1328, 1329, 1353, 1355, 1384, 2149, 2450, 2451, 2455 neurotoxin....................................... 2039 neutrophil.......................................... 433 neutrophils........................................ 681 nevirapine....................................... 1505 new chemicals database...................... 81 New Food borne diseases............... 1211 Next Generation Sequencing.... 126, 151 NF-B................................................. 264 Nf-kappa B............................... 263, 431 NFkappaB............................... 409, 1130 NF-kappaB....................................... 257 NF-kB................................... 2287, 2324 NF-kB/Rel........................................ 399 NGF.................................................. 462 NHANES.................... 1241, 1261, 1693 NHP.................................................. 561 nickel....... 236, 275, 299, 305, 813, 816, 1316, 1604 Nicotinamide.................................. 2584 Nicotine............................................ 111 nitrated proteins.............................. 1286 nitric oxide.................... 261, 1713, 2061 Nitric Oxide Synthase..................... 1295 nitrite............................................... 2381 Nitrogen Mustard............................ 2026 nitrosative stress............................... 637 nitrotyrosine.................................... 1287 nitroxide.......................................... 1407 NK cell.............................................. 693 NLRP3................................................ 57 N-methyl-d-aspartate...................... 2596 N-methyl-D-aspartate (NMDA) receptor 2597 NMR................................................. 167 NNK................................................. 219 No Effect Level.............................. 1947 NO2 Engine emissions................... 1290 NOAEL........................................... 1524 noise.................................................. 160 non alcoholic fatty liver disease..... 2582 Non Human Primate............... 539, 1920 non human primates......................... 562 non small cell lung cancer.............. 1361 Non-additive effects....................... 2305 non-cancer risk assessment............. 1962 Non-cancer toxicity........................ 1945 non-chemical stressor..................... 1794 non-chemical stressors......... 1792, 1793, 1795 nonclinical safety assessment........... 662 Nonclinical Toxicology.................. 1925 Nonclinical vehicles......................... 790 non-coding RNA............................... 899 Non-genotoxic.......................... 874, 875 non-genotoxic hepatocarcinogen.... 1090 nonheme iron enzymes..................... 816 non-Hodgkin lymphoma................... 880 Nonhuman Primate......................... 1645 non-human primate................. 555, 1146 Non-Human Primates..................... 1754 nonlinear......................................... 1960 non-mammalian model species........ 977 Non-small cell lung cancer............... 407 nonthermal food irradiation............ 2413 Non-Traditional Vehicle................... 781 noradrenergic.................................... 177 norepinephrine transporter (NET) ligand 812 normalization.................................... 725 noval formulation............................. 787 NRF1.............................................. 2502 NRF2....... 179, 411, 412, 413, 414, 415, 593, 694, 1009, 1113, 1114, 1116, 1278, 1396, 1787, 1788, 1789, 1790, 2496, 2499, 2503, 2586 Nrf2-Keap1.................... 92, 1786, 1791, 2498, 2500 NRTI................................. 183, 209, 961 NSAID, tolfenamic acid................... 955 NTE................................................ 1335 N-terminal valine adducts............... 1687 NTP Tox21........................................ 493 nuclear receptor....... 225, 348, 354, 376, 2382 nuclear receptors............. 378, 952, 1857 nucleoside reverse transcriptase inhibitors......................................... 1275 nucleotide excision repair........ 113, 115, 116 Oatp.............................. 548, 2247, 2390 obesity.......... 685, 760, 988, 1120, 1200, 1201, 1450, 1698, 1862, 2270, 2345 obesogens....................................... 1201 occupational.................................... 2458 occupational asthma................. 97, 1367 occupational exposure......... 1180, 1220, 1267, 2139, 2156 Occupational exposure limit................. 6 occupational health........................... 911 occupational safety......................... 2504 occupational standard..................... 1529 occurrence....................................... 1221 Ocean.............................................. 2403 ochratoxin............................... 763, 1534 ochratoxin A.............................. 107, 320 Octopus........................................... 2434 ocular................................ 524, 546, 890 Ocular injury................................... 1748 ocular irritation........... 1001, 2550, 2569 ocular safety.......................... 1521, 1553 ocular toxicity................................... 804 Ocular Toxicology.......................... 2568 OECD..................................... 646, 2569 oecd validation study...................... 2380 oedema............................................ 1160 OEL............................ 1803, 2296, 2538 Office Environment........................ 1225 off-target effects................................ 853 off-target pharmacology................... 854 OH-PCB136................................... 1830 OH-PCBs.......................................... 621 oil dispersants................................. 2338 Oil Spill........... 825, 826, 827, 828, 830, 1263, 1963, 2341, 2392 oil spills.......................................... 2340 Olfactory bulb................................. 2595 olfactory dysfunction...................... 2134 Olfactory Sensory Neurons............ 1382 Olfactory toxicity......... 538, 1379, 1380, 1382, 2133, 2319 Olfactory translocation..................... 290 Oligonucleotide................................ 800 Omeprazole....................................... 361 Omic biomarkers........ 1106, 1440, 1441 omics........................... 1585, 1597, 1715 ‘omics............................................. 1734 -omics technologies............................ 42 oncogenes......................................... 236 oncological drugs............................ 1576 Oncology................................ 792, 1427 Ontogenesis.................................... 2662 Ontogeny.......................................... 615 Ontology................................. 728, 2693 oocyte maturation........................... 1072 oocyte meiotic maturation................ 533 oocyte morphology........................... 533 Oocytes........................................... 1342 OP antagonism................................ 2048 OP Hydrolyses................................ 2048 OP pesticides.................................. 1333 Operant behavior.................. 1402, 1886 ophthalmology.................................. 519 opioid drugs...................................... 775 OPs exposure.................................. 1692 Optimum design of experiments...... 478 Oral................................................... 273 oral toxicity............................. 787, 1547 Ordnance Environmental Program.......................................... 1544 organ toxicity.................................. 1671 organic anion transport..................... 763 organic anion transporters.............. 2268 Organic UV Filters......................... 2179 organophosphate........ 1326, 1676, 2049, 2120 Organophosphate Insecticide.......... 1327 Organophosphates..... 1444, 2018, 2098, 2102, 2113 organophosphorous pesticides....... 1330, 2097 organophosphorus........................... 2101 organophosphorus compound......... 2576 Organophosphorus compounds........ 861 Organophosphorus pesticide........... 2117 Organophosphorus pesticides......... 1332 organoselenium............................... 2023 organotin................................. 695, 2393 Organotypic.................................... 2553 organotypic model............................ 466 oryza sativa japonica...................... 2205 Oscillations....................................... 404 osmotic stress.................................. 1276 osteoarthritis..................................... 512 osteoblast.......................................... 276 osteoblast differentiation................ 2217 osteoblastogenesis............................ 352 Osteoblasts...................................... 2369 Osteolathyrism........................ 627, 2312 osteoporosis.............................. 277, 293 outdoor smog chamber..................... 565 Outreach............................... 1867, 1868 Ovarian failure................................ 1065 Ovarian follicle depletion............... 1026 ovarian steroidogenesis.................. 1051 Ovarian toxicology......................... 1036 ovariectomized rat.......................... 2372 ovary........................... 1035, 1054, 1055 oxalate crystals................................. 758 Oxaxolidione.................................... 987 oxidant.................................... 698, 2175 oxidant stress.................................. 1290 oxidative damage............................ 1102 Oxidative Damage............................ 111 Oxidative DNA adducts.................. 1856 oxidative DNA damage.................. 1548 oxidative environmental pollutants.... 22 Oxidative Injury.................... 1274, 1300 oxidative lipidomics............. 1179, 1669 oxidative phosphorylation.... 1304, 2126 396 SOT 50th Anniversary Annual Meeting
Society of Toxicology 2011 Abstract Key Word Index (Continued) The numerals following each key word refer to the relevant abstract number(s). oxidative stress........ 161, 206, 324, 338, 410, 460, 461, 462, 697, 741, 757, 948, 1059, 1099, 1270, 1271, 1276, 1277, 1283, 1284, 1291, 1298, 1301, 1308, 1333, 1376, 1435, 1461, 1462, 1465, 1491, 1510, 1665, 1672, 1716, 1764, 1786, 1788, 1789, 2040, 2063, 2068, 2124, 2128, 2166, 2216, 2488, 2490, 2496, 2498, 2501, 2503, 2583, 2621 Oxidative stress and inflammation......................... 1057, 2495 oxidative stress enzymes................ 2404 oxidized phospholipids..................... 759 oxime.......................... 2014, 2016, 2049 oxycodone......................................... 775 oxygen consumption............. 2528, 2529 Oyster............................................. 2430 ozone.... 26, 592, 604, 1244, 1293, 2286, 2287, 2326 P bodies........................................... 2565 p16.......................................... 104, 2300 p21WAF1........................................ 1791 p27kip1........................................... 1070 p27kip-cyclin D1.............................. 402 p38 mitogen activated protein kinase.............................................. 2064 P450........................................ 885, 1864 p53...................... 117, 1977, 2235, 2315 p53 haploinsufficient mice............... 235 p53 mutation................................... 1953 p53 stabilizer............................ 794, 795 p62 autophage................................. 1791 Pafuramidine..................................... 549 PAH........................................ 355, 1213 PAH-contaminated soil................... 2238 PAHs................. 1074, 1373, 2396, 2524 pain................................................... 512 PAK6................................................ 537 palmitate......................................... 1664 pancreas............................................ 380 pancreatic cancer.................... 225, 1663 pancreatitis...................................... 2347 Paraoxon............................... 2113, 2604 Paraoxonase................ 1270, 1326, 2249 Paraoxonase 1................................. 2024 Paraquat..................... 1295, 1348, 1349, 1665, 2265 Parkinson disease.................... 179, 1396 Parkinsonism.................................... 545 parkinsons disease............................ 980 Parkinson’s disease.......... 168, 181, 182, 841, 843, 1348, 1394, 1779, 2123, 2124, 2134 PARP..................................... 1672, 2574 Particle.................................. 2333, 2491 particle characterization........ 1233, 1801 particles......................... 566, 1235, 1259 particokinetic model....................... 1457 Particulate Matter........................... 2659 particulate matter..... 591, 593, 671, 672, 1213, 1215, 1233, 1570, 2495 Particulate Matter (PM2.5)............ 1170, 2323 Particulate Matters.......................... 1291 partition coefficient......................... 1809 Pathological lesions........................ 1933 Pathology.................................. 201, 536 Pathway analysis...................... 125, 716 Pathway and network analysis........ 1739 pathways........................................... 130 Pax5................................................ 1123 Pb............................................ 293, 1700 Pb toxicity......................................... 293 PBDE.................................... 1667, 2253 PBDE 209....................................... 2604 PBPK............... 700, 707, 709, 721, 736, 889, 941, 2456, 2689, 2691, 2693 PBPK and Biological modeling...... 2307 PBPK model.... 706, 708, 710, 711, 713, 718, 719, 737, 1239, 2690 PBPK Modeling........... 2, 699, 712, 720, 731, 1581, 2141, 2294, 2316, 2460 PBPK models........................ 2457, 2688 PBPK/PD.................................. 723, 866 PC/PS Hemodialyzers.................... 1315 PC12 cells........... 869, 1344, 1345, 1383 PCB......... 1203, 1960, 2250, 2623, 2624 PCB 126................................ 1103, 1109 PCB126........................................... 1854 PCB136........................................... 1830 PCB3 metabolites............................. 335 PCBs.......... 621, 860, 1637, 2245, 2249, 2251, 2404, 2412, 2601, 2602, 2603 PCLis.............................................. 1004 PCR-RFLP...................................... 1374 PDE4 Inhibitor.................................. 542 PDTC/Cu complex........................... 300 penetration........................................ 632 Penh................................................ 2299 peppermint oil................................. 1107 Peptide Adducts.............................. 1679 peptide aggregation.......................... 734 peptide reactivity.............. 90, 905, 2545 Percellome...................................... 1596 perfluorinated compounds.... 1221, 1636 Perfluorinated Phosphonic Acid..... 1625 Perfluoroalkyl acid......................... 2240 perfluorochemicals................. 657, 2240 Perfluorooctane sulfonate............... 2243 Perfluorooctanoate.......................... 2557 perfluorophosphonic acid............... 2239 Perinatal.............................................. 15 Perinatal Exposure................ 1078, 2606 perinatal hypothyroidism................ 1618 Peripheral Neuropathy.................... 2616 Permeability transition.................... 1087 peroxidation.................................... 2385 peroxisome proliferator-activated receptor gamma...................... 957, 2661 Persistant Organic Chemicals, POP, Flame Retardant..................... 2248 persistent organic pollutants (POPs)....... 212, 1200, 1202, 1593, 2244 Personal Care Products................... 1551 personality........................................ 628 pesticide............... 181, 692, 1038, 1222, 1329, 1350, 1351, 1549, 1680, 1964, 2118, 2339, 2517 Pesticide exposure.......................... 1218 Pesticide Mixtures.......................... 1346 Pesticides......... 105, 168, 242, 388, 531, 703, 704, 705, 864, 1202, 1250, 1328, 1779, 2110, 2111, 2112, 2115, 2116, 2120, 2244, 2387 PET Imaging Agent.......................... 812 petroleum.......................................... 108 petroleum diesel.............................. 2489 PFAA.............................................. 2247 PFAAs............................................... 706 PFBA.............................................. 1242 PFHXA........................................... 2272 PFHxS................................... 2237, 2272 PFOA....... 205, 1089, 1242, 1609, 1620, 1622, 2271 PFOA/PFOS................................... 2273 PFOS..................... 658, 659, 1242, 2271 P-glycoprotein........................ 241, 2267 P-glycoprotein/ABCB1.................. 2265 pH effects........................................ 2155 pha.................................................. 1206 Phagocytic activation........................ 251 Phagocytosis........................... 263, 1272 Phamacokinetics............................. 2263 Pharmaceutical... 894, 2368, 2677, 2680 pharmaceutical agents.................... 2681 Pharmaceutical Ecotoxicology....... 2400 pharmaceutical treatment................ 2594 Pharmaceuticals................... 1563, 1608, 1836, 2384 pharmacogenomics......................... 1737 Pharmacokinetic............. 517, 856, 1809 pharmacokinetic and pharmacodynamic modeling............ 864 pharmacokinetic model.................. 2692 pharmacokinetics......... 48, 51, 726, 732, 808, 920, 1266, 2056, 2100, 2257, 2258, 2262, 2274, 2281 pharmacological promiscuity........... 853 Pharmacological similarity............... 156 Pharmacology....................... 1886, 2512 phase I............................................. 1706 phase II........................................... 1706 Phase II biotransformation............. 1824 Phencyclidine................................. 2596 Phenethyl Alcohol.......................... 1034 phenobarbital........................ 2356, 2639 phenotype............................... 363, 1718 Phosphatases..................................... 226 phosphatidylserine.......................... 1669 Phosphatidylserine exposure............ 294 Phosphodiesterase............................. 391 Phospholipidosis............ 136, 436, 1426, 1452 Phospholipids................................. 2195 phosphorylated kinase.................... 2159 Photocarcinogenesis....................... 1785 photocarcinogenicity........................ 796 Photo-clastogenicity......................... 334 photoelectrocatalysis............ 2408, 2409 photosynthesis................................ 2385 Phototosensitization........................ 2542 Phototoxicity.......... 157, 464, 638, 1012, 2078, 2541 phthalate...... 67, 234, 1022, 1036, 1066, 1216, 1243, 1569, 2202, 2370 phthalates............. 20, 1039, 1055, 1201, 1611, 2378 Phthalimide and phthalic acid........ 2260 phycotoxins................. 2225, 2226, 2402 Physical chemical............................. 852 physicochemical characterization of particles........................................ 847 physiochemical property...... 1650, 2177 physiologically based kinetic modeling........................................... 991 physiologically based pharmacokinetic modeling...... 865, 938, 1582 Phytoestrogen....................... 2197, 2198 phytoestrogens............ 1053, 1062, 2362 phytopolyphenols............................. 161 Pig-a.............................. 315, 1406, 1416 PIK3CA............................................ 239 Pill................................................... 1765 piperine........................................... 2208 PK................................................... 1929 PKC................................................ 2208 placenta................................. 1058, 1074 plant toxin....................................... 2229 Plastics.............................................. 624 Platelet............................................ 1884 Platelets............................................. 778 Platycodon Grandiflorum.... 2207, 2209, 2211, 2213, 2217 PLD................................................. 1299 pleura.................................... 2176, 2178 Pleural pressure................................ 576 Plicopurpura pansa......................... 2393 PLLA.............................................. 1322 Pluripotent Stem Cells.......... 1163, 1164 PM Exposure.................................. 2332 PM health effects............................ 2494 pmk-1.............................................. 2064 PML.................................................. 660 PMSF.............................................. 2101 Pneumotachometer, Correlation analysis............................................. 576 POCIS............................................. 2398 point of zero charge........................ 2177 Pol Eta.............................................. 120 Policy.............................................. 1527 pollutant.......................................... 1085 pollution................................ 1543, 2396 pollution burden................................ 472 polybrominated diphenyl ether...... 1771, 2599 Polybrominated diphenyl ethers.... 1818, 2605 polybrominated diphenyl ethers (PBDEs)................................ 1607, 2252 Polychlorinated biphenyls..... 260, 1820, 2242 polychlorinated biphenyls (PCBs )... 1203, 1495, 2360, 2600, 2625 polychloroprene.............................. 1557 Polycyclic Aromatic Hydrocarbon... 526 polycyclic aromatic hydrocarbons........................ 1229, 2566 polycyclic aromatic hydrocarbons, Benzo(a)pyrene............................... 1138 Polyethylene Glycol......................... 781 poly-l-lactic acid............................. 1322 polymorphism............. 1361, 1362, 1778 polymorphisms..................... 1255, 1372 polyphenols............................. 995, 2231 Polysorbate 80...................... 1911, 1916 polystyrene nanosphere.................... 719 PON 1............................................. 1371 PON1.............................................. 1209 POP................................................. 2241 POPs..................................... 2200, 2305 population diversity.......................... 820 population variability....... 501, 713, 819, 1984 port catheter system........................ 1566 Positive Control.............................. 2654 postmenopausal women.................... 277 postnatal.......................................... 2663 postnatal body weight..................... 1025 Postnatal Development................... 2190 post-translational modifications....... 214 potassium bromate.......................... 1273 potentiation....................................... 766 PPAR.... 234, 354, 358, 716, 1120, 1609 PPAR agonist.................................. 1437 PPAR alpha........................... 2237, 2240 PPAR beta......................................... 357 PPARa............................................... 366 PPARa............................................... 379 PPAR-alpha.......................... 1089, 2239 PPARb/d................................... 355, 359 PPARg...................................... 345, 352 PPD................................................. 1863 Pralidoxime..................................... 2018 prasugrel........................................... 777 pre and postnatal exposure............. 1636 Precision-Cut Liver Slices............. 1014, 1900, 2509 Precision-cut lung slices................... 960 precision-cut tissue slices............... 1766 Preclinical..................................... 3, 806 preclinical safety..................... 518, 1917 preclinical studies........................... 1927 Preclinical Toxicology............ 507, 1141 Prediabetes...................................... 2201 prediction........................................ 1410 Prediction Model.................... 717, 1598 Prediction Tools.............................. 1814 Predictive in vitro model................ 2537 predictive methods.................... 148, 902 predictive modeling........................ 1587 Predictive models............................. 852 Predictive toxicology.............. 123, 2679 Pregnancy........ 1067, 1625, 1985, 2186, 2197, 2506 pregnane X receptor......................... 377 pregnane X receptor (PXR)............ 1840 prenatal cigarette smoke................. 2194 prenatal exposure.......... 611, 1208, 2607 Prenatal stress....................... 1639, 1699 Key Word Index up-to-date information at www.toxicology.org 397
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50 th Anniversary Annual Meeting &
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Scientific Program Overview A page
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9:00 AM-12:30 PM POSTER SESSionS
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March 6-10, 2011 Walter E. Washingt
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Celebration Activities Historical H
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of the Society Regional Chapter Yea
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SOT Presidents 1961-2011 1966 1967
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The SOT Council Thanks and Recogniz
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of the Past 50 Years 2003 Michael D
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2011 SOT 50 th Anniversary Featured
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Program - Society of Toxicology

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