Program - Society of Toxicology

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50 th Anniversary Annual Meeting and ToxExpo Program Description (Continued) Wednesday Abstract # Abstract # #1974 Poster Board Number.....................................507 SEAFOOD INTAKE AND URINE CONCENTRATIONS OF TOTAL ARSENIC, DIMETHYLARSINATE, AND ARSENOBETAINE IN THE U.S. POPULATION. A. Navas-Acien 1,2 , K. A. Francesconi 3 , E. K. Silbergeld 1 and E. Guallar 2 . 1 Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 2 Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD and 3 Institute of Chemistry, Karl-Franzens University Graz, Graz, Austria. #1975 Poster Board Number.....................................508 DIFFERENTIAL MODULATION OF CYP1A1 BY ARSENITE IN VIVO AND IN VITRO IN C57BL/6 MICE. A. Anwar-Mohamed and A. O. El-Kadi. Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada. #1976 Poster Board Number.....................................509 ROLE OF CONTINUOUS LOW-LEVEL MONOMETHYLARSONOUS ACID EXPOSURE IN THE INHIBITION OF PARP AND CONTRIBUTION TO INCREASED GENOTOXICITY IN THE MALIGNANT TRANSFORMATION OF UROTSA CELLS. S. M. Wnek, M. M. Medeiros, J. M. Camarillo, T. J. Jensen, X. Zheng, B. W. Futscher and A. Gandolfi. Pharmacology and Toxicology, University of Arizona, Tucson, AZ. #1977 Poster Board Number.....................................510 P53 RESPONSE TO MONOMETHYLARSONOUS ACID EXPOSURE IN HUMAN BLADDER EPITHELIAL CELLS. M. K. Medeiros and A. Gandolfi. Pharmacology and Toxicology, University of Arizona, Tucson, AZ. #1978 Poster Board Number.....................................511 IN VIVO CONSEQUENCES OF ARSENIC METHYLATION IN A DROSOPHILA MODEL. I. Cartwright 1 , J. Muñiz Ortiz 2 and J. Shang 1 . 1 Molecular Genetics, University of Cincinnati College of Medicine, Cincinnati, OH and 2 NHEERL, U.S. EPA, Research Triangle Park, NC. #1979 Poster Board Number.....................................512 ASSOCIATION OF ARSENIC EXPOSURE AND GENETIC POLYMORPHISMS WITH ARSENIC METABOLISM IN A VIETNAMESE POPULATION. T. Agusa 1,2 , T. Kunito 3 , J. Fujihara 1 , H. Takeshita 1 , T. B. Minh 4 , P. K. Trang 4 , P. H. Viet 4 , S. Tanabe 2 and H. Iwata 2 . 1 Shimane University Faculty of Medicine, Izumo, Japan, 2 Ehime University, Matsuyama, Japan, 3 Shinshu University, Matsumoto, Japan and 4 Vietnam National University, Hanoi, Viet Nam. #1980 Poster Board Number.....................................513 AS3MT/M287T POLYMORPHISM IS A RISK FACTOR FOR DIABETES ASSOCIATED WITH CHRONIC EXPOSURE TO INORGANIC ARSENIC. D. Loomis 1 , L. M. Del Razo 2 , G. G. Garcia-Vargas 3 , Z. Drobná 4 and M. Styblo 4 . 1 Medical Center, University of Nebraska, Omaha, NE, 2 Department of Toxicology, Cinvestav- Ipn, Mexico, Mexico, 3 Faculty of Medicine, Juarez University of Durango State, Gomez-Palacio, Mexico and 4 Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC. #1981 Poster Board Number.....................................514 METHYLATION OF ARSENIC BY RECOMBINANT HUMAN AS3MT/287M AND AS3MT/287T POLYMORPHS. L. Ding 1 , J. Saunders 1 , Z. Drobná 1 , D. J. Thomas 2 and M. Styblo 1 . 1 Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC and 2 ETD, NHEERL, U.S. EPA, Research Triangle Park, NC. #1982 Poster Board Number.....................................515 GST-T1 AND GST-M1 GENOTYPES MODULATE THE METABOLISM AND DIABETOGENIC EFFECTS OF INORGANIC ARSENIC. Z. Drobna 1 , L. Del Razo 2 , G. Garcia- Vargas 3 , D. Loomis 4 and M. Styblo 1 . 1 Nutrition, CB#7461, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2 Toxicology, Cinvestav-Ipn, Mexico City, Mexico, 3 Faculty of Medicine, Juarez University of Durango State, Durango, Mexico and 4 Epidemiology, University of Nebraska Medical Center, Omaha, NE. #1983 Poster Board Number.....................................516 ARSENIC METHYLATION IS ASSOCIATED WITH BREAST CANCER RISK IN NORTHERN MEXICO. M. E. Cebrián 1 , A. Gandolfi 2 , R. U. Hernandez 3 , J. M. Ornelas 4 , L. Torres-Sanchez 3 and L. Lopez-Carrillo 3 . 1 Toxicology, Cinvestav IPN, Mexico City, DF, Mexico, 2 Pharmacology and Toxicology, University of Arizona, Tucson, AZ, 3 CISP, INSP, Cuernavaca, Morelos, Mexico and 4 Pathology, IMSS, Ciudad Obregón, Sonora, Mexico. #1984 Poster Board Number.....................................517 INFLUENCE OF INDIGENOUS AMERICAN ANCESTRY AND BODY MASS INDEX ON ARSENIC METHYLATION EFFICIENCY IN NORTHWEST MEXICO. P. Gomez-Rubio 1 , M. M. Meza-Montenegro 2 , E. Cantu-Soto 2 , Y. C. Klimentidis 3 and W. T. Klimecki 1 . 1 Pharmacology and Toxicology, University of Arizona, Tucson, AZ, 2 Environmental Sciences, Instituto Tecnologico de Sonora, Obregon, Sonora, Mexico and 3 Biostatistics, University of Alabama at Birmingham, Birmingham, AL. #1985 Poster Board Number.....................................518 THE INFLUENCE OF GENETICS, NUTRITION, AND PREGNANCY ON ARSENIC METABOLISM: A LONGITUDINAL COHORT STUDY. R. M. Gardner 1 , K. Engström 2 , K. Broberg 2 and M. Vahter 1 . 1 Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden and 2 Department of Laboratory Medicine, Lund University, Lund, Sweden. 290 Education-Career Development Sessions Exhibitor Hosted Sessions Featured Sessions Historical Highlights Informational Sessions Platform Sessions
Society of Toxicology 2011 Program Description (Continued) Abstract # #1986 Poster Board Number.....................................519 DETECTION AND STABILITY OF METHYLATED TRIVALENT ARSENIC METABOLITES IN MOUSE LIVER HOMOGENATES. J. Currier 1 , J. Saunders 2 , Z. Drobná 2 and M. Styblo 2 . 1 Curriculum in Toxicology, University of North Carolina at Chapel Hill, Chapel Hill, NC and 2 Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC. #1987 Poster Board Number.....................................520 THE EFFECT OF PRENATAL FOLATE SUPPLEMENTATION ON DNA METHYLATION AND GENE EXPRESSION IN MALE CD1 MOUSE FETUSES EXPOSED IN UTERO TO ARSENIC. V. Tsang 1 , R. Fry 2 , M. Niculescu 3 , J. Saunders 1 , M. Waalkes 4 , M. Styblo 1 and Z. Drobna 1 . 1 Nutrition, CB#7461, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2 Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, 3 Nutrition Research Institute, Kannapolis, NC and 4 NTP at NIEHS, Research Triangle Park, NC. #1988 Poster Board Number.....................................521 AUTOPHAGY: A CELLULAR PROCESS STRONGLY ASSOCIATED WITH ARSENITE- INDUCED IMMUNOTOXICITY IN HUMAN LYMPHOBLASTOID CELL LINES. A. M. Bolt, R. M. Douglas and W. T. Klimecki. Pharmacology and Toxicology, University of Arizona, Tucson, AZ. #1989 Poster Board Number.....................................522 DEVELOPMENTAL IMMUNOTOXICITY OF LOW DOSE ARSENIC EXPOSURE. C. Kozul-Horvath 1 , J. W. Hamilton 2 and R. Enelow 1 . 1 Immunology, Dartmouth Medical School, Lebanon, NH and 2 Bay Paul Center for Comparative Molecular Biology & Evolution, Marine Biological Laboratory, Woods Hole, MA. #1990 Poster Board Number.....................................523 ARSENIC ALTERS PURINERGIC TYPE 2 (P2) RECEPTOR Ca 2+ SIGNALING ASSOCIATED WITH INNATE IMMUNITY IN HUMAN AIRWAY EPITHELIAL CELLS. C. L. Sherwood 1,2,5 , R. Lantz 2,4,5 , J. L. Burgess 4,6 and S. Boitano 1,3,4 . 1 Arizona Respiratory Center, Arizona Health Sciences Center, Tucson, AZ, 2 Cell Biology and Anatomy, Arizona Health Sciences Center, Tucson, AZ, 3 Physiology, Arizona Health Sciences Center, Tucson, AZ, 4 SWEHSC, Arizona Health Sciences Center, Tucson, AZ, 5 Bio5 Institute, Arizona Health Sciences Center, Tucson, AZ and 6 College of Public Health, Arizona Health Sciences Center, Tucson, AZ. #1991 Poster Board Number.....................................524 SODIUM ARSENITE AND HYPERTHERMIA ALTER EXPRESSION OF XPA, XPC, AND MSH2 IN RESPONSE TO CISPLATIN- INDUCED DNA DAMAGE AND INCREASE ACCUMULATION OF PLATINUM IN OVARIAN CANCER. C. S. Muenyi 1 , V. A. States 1 , J. H. Masters 1 , T. Fan 1,2 , W. Helm 1,3 and J. States 1 . 1 Pharmacology & Toxicology, University of Louisville, Louisville, KY, 2 Chemistry, Univesity of Louisville, Louisville, KY and 3 Obstetrics, Gynecology & Women’s Health, Univesity of Louisville, Louisville, KY. Abstract # #1992 Poster Board Number.....................................525 EPITHELIA MALIGNANTLY TRANSFORMED BY ARSENIC OR CADMIUM DRIVES NEARBY NORMAL STEM CELLS TOWARDS A MALIGNANT PHENOTYPE. Y. Xu, E. Tokar and M. Waalkes. National Toxicology Program, NIEHS, Research Triangle Park, NC. #1993 Poster Board Number.....................................526 OVERABUNDANCE OF PUTATIVE CANCER STEM CELLS IN HUMAN SKIN KERATINOCYTE CELLS MALIGNANTLY TRANSFORMED BY ARSENIC. Y. Sun, E. Tokar and M. Waalkes. National Toxicology Program, NIEHS, Research Triangle Park, NC. #1994 Poster Board Number.....................................527 TRANSFORMATION OF NORMAL HUMAN BREAST EPITHELIAL (MCF-10A) CELLS BY ARSENITE AND CADMIUM INDUCES THE OVER-EXPRESSION OF NEURONAL SPECIFIC ENOLASE (ENOLASE-2). M. Soh, S. H. Garrett, C. Bathula, D. A. Sens, S. Somji and M. Sens. Pathology, University of North Dakota, Grand Forks, ND. #1995 Poster Board Number.....................................528 SPARC GENE EXPRESSION IS REPRESSED IN HUMAN UROTHELIAL CELLS (UROTSA) EXPOSED TO OR MALIGNANTLY TRANSFORMED BY CADMIUM OR ARSENITE. J. L. Larson 1 , S. Somji 2 , D. A. Sens 2 , M. Sens 2 , S. H. Garrett 2 and J. R. Dunlevy 1 . 1 Anatomy and Cell Biology, University of North Dakota, Grand Forks, ND and 2 Pathology, University of North Dakota, Grand Forks, ND. #1996 Poster Board Number.....................................529 DIFFERENCES IN THE EPIGENETIC REGULATION OF METALLOTHIONEIN-3 GENE EXPRESSION BETWEEN PARENTAL AND CADMIUM- OR ARSENITE- TRANSFORMED HUMAN UROTHELIAL CELLS. D. A. Sens, S. H. Garrett, A. Ajjimaporn, M. Sens and S. Somji. Pathology, University of North Dakota, Grand Forks, ND. #1997 Poster Board Number.....................................530 IL-8 OVER-EXPRESSION AND AUTOCRINE CELL ACTIVATION ARE KEY FACTORS IN MONOMETHYLARSENOUS ACID [MMA(III)]-INDUCED MALIGANT TRANSFORMATION OF HUMAN UROTHELIAL CELLS. C. Escudero 1,2 , T. Wu 2 , J. M. Camarillo 2 and A. Gandolfi 2 . 1 Inmunologia y Biologia Celular y Molecular/CIEP, Universidad Autonoma de San Luis Potosi, SLP, Mexico and 2 Department of Pharmacology and Toxicology, University of Arizona, Tucson, AZ. Wednesday Poster Sessions Regional Interest Session Roundtable Sessions Symposium Sessions Thematic Sessions Workshop Sessions 291
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50 th Anniversary Annual Meeting &
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Scientific Program Overview A page
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9:00 AM-12:30 PM POSTER SESSionS
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March 6-10, 2011 Walter E. Washingt
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Celebration Activities Historical H
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of the Society Regional Chapter Yea
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SOT Presidents 1961-2011 1966 1967
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The SOT Council Thanks and Recogniz
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of the Past 50 Years 2003 Michael D
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Thank You to the following individu
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SOT Celebration Event Floor Plan Ba
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Toxicological Sciences The Official
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Society of Toxicology 2011 Walter E
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Society of Toxicology 2011 Washingt
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2011 SOT 50 th Anniversary Featured
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Society of Toxicology 2011 Washingt
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Society of Toxicology 2011 ToxExpo
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Society of Toxicology 2011 Exhibito
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Creating a Safer and Healthier Worl
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Society of Toxicology 2011 General
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SOT Job Bank YOUR RECRUITMENT AND E
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Society of Toxicology 2011 SOT 2011
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Society of Toxicology 2011 2011 Awa
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Society of Toxicology 2011 SOT Endo
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Society of Toxicology 2011 Recognit
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Society of Toxicology 2011 Recognit
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Society of Toxicology 2011 RC, SIG,
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Society of Toxicology 2011 Student
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Society of Toxicology 2011 Outreach
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Society of Toxicology 2011 Satellit
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Society of Toxicology 2011 Author I
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Society of Toxicology 2011 2010-201
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Society of Toxicology 2011 Elected
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Society of Toxicology 2011 Elected
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