50 th Anniversary Annual Meeting and ToxExpo Abstract Key Word Index (Continued) The numerals following each key word refer to the relevant abstract number(s). Key Word Index Thrombocytopenia............................ 778 Thrombopoietin................................ 284 thrombosis........................................ 190 Thryoid Hormone........................... 2360 thyroid................................... 2608, 2668 Thyroid disruption.......................... 2350 Thyroid Gland................................ 1423 thyroid hormone................... 1618, 2349 Thyroid hormones.......................... 2135 tiered approach............................... 1001 Time-Course..................................... 194 time-dependent............................... 1718 time-dependent inhibition............... 2280 TIMP-2............................................... 66 TiO2...................................... 2073, 2078 TiPARP................................... 356, 1599 Tissue Cross Reactivity.................... 881 Tissue distribution.......................... 2386 Tissue Dosimetry............................ 1719 Tissue exposure................................ 856 tissue:air partition coefficient (Pta).................................................. 722 Tissue-Selective Carcinogens........... 488 titanium dioxide...................... 655, 1483 Titanium dioxide nanoparticles..... 1455, 1461, 1471, 2066, 2077 Titanium dioxide particles.............. 1801 titanium nanoparticle...................... 2180 titanium nanoparticles.................... 1454 Titanium Nanostructure.................. 2061 titanium particulates......................... 566 TLR4................................................. 697 TNIP1............................................... 384 Tobacco...................... 1372, 2694, 2695, 2698, 2699 tobacco carcinogens........................ 2697 Tobacco products............................ 2696 Tobacco smoke.... 969, 990, 1409, 1565, 2295, 2330 tobacco toxicant biomarkers............ 834, 2697 TOC................................................ 1523 Toll Like Receptors.......................... 686 toll-like receptor 4.......................... 1495 Toluene................................. 1298, 1583 topiramate......................................... 810 Torcetrapib................................ 387, 556 Tottering......................................... 1385 ToxCast..................... 141, 143, 715, 727 toxic effects..................................... 2392 Toxic Load........................................ 572 toxic tort.......................................... 2152 Toxicant Exposure............................ 749 Toxicant susceptibility.................... 1395 Toxicants......................................... 2295 Toxicity.............................................. 10, 18, 266, 275, 305, 515, 582, 746, 797, 820, 930, 1250, 1453, 1668, 1740, 1821, 1826, 1882, 1883, 1900, 2004, 2006, 2076, 2206, 2407, 2408, 2426, 2631 Toxicity Biomarkers in Mouse Lung.................................................. 671 toxicity mechanisms........ 569, 735, 939, 2060, 2590 Toxicity path..................................... 134 toxicity pathway........... 822, 1813, 2505 Toxicity pathways................... 962, 1583 Toxicity prediction...................... 33, 935 toxicity screening.............................. 973 Toxicity study................................. 1574 Toxicity Testing in the 21st century.................................... 2505 toxicogenomic................................ 1541 toxicogenomics.................... 19, 41, 124, 138, 139, 436, 823, 824, 906, 917, 1586, 1589, 1593, 1603, 2073, 2152, 2401, 2651, 2652, 2681 Toxicogenomics and mode <strong>of</strong> action.......................................... 1596 Toxicogenomics, Hepatotoxicity, Liver..................................... 1592, 1606 Toxicokinetic................ 517, 2108, 2259 Toxicokinetics.... 807, 1230, 1240, 2105, 2107, 2265, 2271, 2272, 2693 toxicological screening................... 2519 <strong>Toxicology</strong>........... 5, 8, 47, 56, 592, 788, 1576, 2676 <strong>Toxicology</strong> 21................................. 1309 <strong>Toxicology</strong> education..................... 1874 toxicology history............................. 922 <strong>Toxicology</strong> Jobs.............................. 1879 toxicology screening........................... 14 <strong>Toxicology</strong> training........................ 1876 Toxicophores.................................... 153 toxicoproteomics............ 128, 513, 2500 toxin................................................ 2219 ToxInsight......................................... 398 TPP1................................................. 801 trace metals..................................... 2395 Traditional medicine....................... 2206 training............................................ 1877 Transcript ‘Omics............................. 489 transcript pr<strong>of</strong>iling............................ 868 transcription factor.................. 410, 1969 transcriptional alterations............... 2633 transcriptional regulation................ 2647 transcriptome................ 387, 1599, 1627 transcriptomics.................. 60, 79, 1591, 1600, 1718 Transcriptomics /gene expressing............................. 1595, 2378 transepithelial electrical resistance........................................ 1021 Transfluthrin................................... 2646 transformation......................... 236, 1155 Transforming growth factor beta... 1293, 2330 transgenic animal model................... 204 transgenic mice............................... 2578 transglutaminase............................. 1515 transition metal oxide nanoparticles................................... 2177 translational imaging...................... 1322 translational inhibition.................... 2565 Translational <strong>Toxicology</strong>................ 1014 translocation................................... 2163 transplacental carcinogenesis......... 2665 transplacental exposure........ 2169, 2506 transport........................ 761, 1478, 2247 transport kinetics.............................. 311 Transporters....... 938, 1047, 1077, 1079, 1706, 2269 triaryl phosphate............................... 169 triazoles............................................... 71 tributyltin................................ 663, 2388 Tributyltin (TBT)............................ 1068 Trichloroacetate................................ 251 Trichloroacetic acid........................ 2283 Trichloroethene............................... 1510 trichloroethylene.......... 550, 1685, 1836, 2641, 2687 Trichloroethylene,........................... 1817 trichothecene................................... 2424 Triclosan......................... 254, 379, 2350 trimethyltin..................................... 1375 Triple Uptake Inhibitors................. 1430 trivalent chromium........................... 915 trivalent methylated metabolites..... 1986 Troglitazone.................. 510, 1080, 2633 trophoblast...................................... 1056 troponin............................................. 555 troponin I.............................. 1161, 1437 TRP channel................................... 2335 TRPA1............................................ 2334 TSCA................................................ 417 TSPO/PBR........................................ 164 TTC......................................... 487, 1767 tubulin............................................... 335 tularemia......................................... 2042 Tumor Analysis................................. 490 tumor necrosis factor..... 109, 238, 1508, 1658 tumor progression............................. 777 tumor transcriptome........................ 1707 tumorigenesis.......................... 234, 2636 Tungstate.......................................... 656 tungsten............... 291, 1383, 1604, 2310 Tungsten alloy.................................. 290 turkey................................................ 972 Tutorial........................................... 1875 two-electron reduction.................... 1305 Two-generation reproductive toxicity............................................ 1044 Type 2 diabetes.......... 1281, 2468, 2469, 2470, 2473, 2582 Tyrosine hydroxylase...................... 1400 ubiquitination.................................... 306 ubiquitin-conjugating enzyme.......... 770 UC-II............................................... 1893 Uganda............................................ 2206 UGT.................................................. 385 Ultrafine Particles......... 191, 1491, 2488 ultrafine particulates......................... 596 ultrasound imaging......................... 1092 ultraviolet light............................... 1784 Umbilical cord........................ 621, 2200 Uncertainty Factor............................ 866 uncertainty factors............................ 713 uncoupling proteins.......................... 958 Undergraduate Education.... 1871, 1873, 1874 Undergraduate research.................. 1872 Unexploded Ordnance...................... 927 Unfolded Protein Response............ 1083 uptake................................... 2165, 2562 Uptake kinetics....................... 313, 2390 uranium................................... 282, 1696 urban particulate matter.................... 571 Urethane........................................... 286 Urinary............................................ 1679 urinary biomarkers.................. 742, 1694 Urinary bladder....................... 232, 2646 Urinary Cadmium..................... 767, 768 urinary fibrinogen............................. 744 urinary protein biomarker................. 743 Urine biomarkers.............................. 463 urothelial carcinomas........................ 250 UROtsa........................................... 1162 Usnic acid....................................... 2418 UV.................................................... 113 uv inactivation................................ 2413 UVA.................................................. 638 UVB................................................ 2033 vaccine potency.............................. 2581 vaccine safety................................. 2581 vaccine safety assessment............... 1027 vaginal irritation testing........ 1049, 1314 vaginal tissue model............. 1049, 2373 validation..................... 529, 1016, 1017, 2152, 2545 Valproic acid..................................... 992 Vanadium.......... 284, 285, 286, 287, 288 vanadium pentoxide.......................... 289 Vanin-1............................................. 444 vapor intrusion................................ 1236 vapor uptake modeling................... 2289 variability........................................ 2691 vascular........................................... 1493 vascular development....... 836, 837, 840 vascular injury........................ 838, 2671 Vascular permeability....................... 959 Vascular reactivity............................ 193 vascular toxicity.............................. 2670 Vasculitis....................... 797, 2669, 2673 VCD................................................ 1054 vector control.................................. 1476 vegan bone treat.............................. 2410 vegetable......................................... 2119 VEGFR1......................................... 2587 vehicle-effect.................................... 963 vehicles............................................. 963 Ventilator-associated pneumonia.... 2337 vesicant........................................... 1751 Vesicant injury.............. 894, 2031, 2033 vesicants............................... 1752, 2032 Vibrio vulnificus............................... 688 Vimentin......................................... 2637 Vinculin.......................................... 1386 viral infection.................................... 256 Viral load monitoring..................... 1149 virtual liver....................................... 733 Virtual Tissues................................ 1619 Vitamin A........................................ 2411 Vitamin D....................................... 2412 Vitamin K....................................... 1613 Vitamin-status................................... 310 vitellogenin................................. 17, 976 VMAT2..................................... 181, 182 VOC...................................... 1424, 1693 VOCs.................................... 1573, 1952 volatile organic compounds..... 502, 596, 977, 1245, 2399 VX.............................. 1543, 2011, 2022 warfare organophosphates.............. 2047 water column.................................... 827 watercress....................................... 2232 weapons............................................ 930 weathering........................................ 827 Weight <strong>of</strong> Evidence...... 727, 1944, 1948 welding............................................. 563 welding fume........................ 2317, 2322 Werner syndrome protein................. 121 WGA............................................... 1369 whale cells............................ 2342, 2392 Wistar Rats................. 1552, 1574, 1951 WKY rats........................................ 1062 Wnt................................................. 1624 Wnt signaling.................................. 1626 Wnt/b-Catenin................................ 1741 Wnt/beta catenin pathway................ 249 Wood combustion..................... 671, 672 wood furnace.................................. 1213 wood smoke.................................... 1127 Workers........................................... 1218 Wound................................... 2021, 2022 wound healing...... 893, 895, 2534, 2556 wound repair................................... 2575 Writing............................................ 1768 WTC..................................... 1235, 1259 xCT Transporter.............................. 1513 xenobiotic metabolism............ 647, 1707 xenobiotics........................................ 376 Xenoestrogens.................................. 110 Xenopus.......................................... 2379 Xenopus laevis.................................. 347 Xpa(-/-)p53(+/-) mice..................... 2658 XPC...................................... 1360, 1991 X-radiation.......................................... 65 x-ray fluorescence (xrf).................. 1686 yeast........................................ 340, 2558 yeast deletion library...................... 2253 Y-family DNA Polymerases............. 120 Yil006w............................................ 308 Yucatan Minipig............................... 635 Zebrafish.......................... 197, 198, 871, 873, 896, 897, 898, 942, 976, 1071, 1461, 1479, 1483, 1588, 1629, 1633, 1642, 1740, 1741, 1742, 1743, 1744, 1745, 1746, 1747, 1779, 1840, 1859, 2090, 2093, 2142, 2143, 2144, 2168, 2310, 2339, 2363, 2388, 2389, 2514, 2539, 2548, 2628 Zebrafish embryo toxicity... 1607, 1610, 1627, 2380 zebrafish larvae....................... 872, 1895 Zidovudine...................................... 1304 Zinc................................................... 314 zinc deficiency.................................. 756 zinc finger nuclease.......................... 535 400 SOT 50th Anniversary Annual Meeting
<strong>Society</strong> <strong>of</strong> <strong>Toxicology</strong> 2011 Abstract Key Word Index (Continued) The numerals following each key word refer to the relevant abstract number(s). Zinc nanoparticles................ 1496, 2060 Zinc Oxide Nanoparticles............... 2179 ZIP transporters........................ 313, 314 ziram................................................. 691 zygacine.......................................... 2229 Key Word Index up-to-date information at www.toxicology.org 401
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