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50 th Anniversary Annual Meeting and ToxExpo Abstract Key Word Index (Continued) The numerals following each key word refer to the relevant abstract number(s). Key Word Index preservatives................................... 2570 pressure sensors.............................. 1930 preterm birth..... 1052, 1057, 1076, 2563 Prevalidation................................... 2551 Preventive Medicine....................... 1225 Primary B Cells.............................. 1137 Primary cell cultures....................... 1332 Primary dendritic cells...................... 967 primary hepatocyte culture... 1656, 2511 primary hepatocytes.............. 1861, 2523 Primate.................................. 1914, 1924 primates.............................................. 26 Primrose.......................................... 2442 prion.................................. 841, 844, 845 prion disease..................................... 173 problem formulation....................... 2507 Procoagulant activation.................. 1884 Product Design............................... 2696 product development...................... 2564 Profenofos....................................... 2117 professional development............... 2484 Program development..................... 1876 prohapten...................................... 86, 88 Prohormone convertase.................. 2089 proinflammatory............................. 1748 proinflammatory mediators.............. 260 Prolactin.......................................... 2372 proliferation.............................. 639, 951 promoter........................................... 397 Pro-oxidant actions......................... 1307 propanol.......................................... 2294 propentofylline................................. 506 propiconazole......................... 951, 2109 propyl acetate.................................. 2294 propyl paraben................................ 1823 Prostate........................................... 1624 Prostate cancer...................... 1043, 2091 prostate development...................... 1626 proteasome...................................... 2490 Protein................... 127, 842, 1730, 2453 protein adducts...................... 1262, 1433 protein aerosol.................................. 589 Protein binding............................... 2348 protein corona................................. 1488 protein denaturation........................ 1733 protein hydrolysates............................ 89 Protein Kinase.................................... 34 protein kinase C.............................. 2131 Protein Ligand Binding.................... 408 Protein Microarray.......................... 1442 protein safety.... 1728, 1731, 1732, 1733 Protein-protein interaction network............................................. 134 proteins........................................... 1729 proteolytic enzymes............................ 96 proteome......................................... 2136 Proteomics....................... 129, 213, 970, 1084, 1283, 1286, 1446, 1450, 1745, 2017, 2159, 2223, 2387 proteomics...................................... 1284 Pseudoallergic & anaphylactoid reactions................................................ 7 pseudoallergy.................................. 1500 Pseudoestrogens............................. 2256 Pseudomonas aeruginosa................ 2337 Psidium guajava.............................. 2218 PTEN................................................ 954 PTH................................................. 2376 pubertal assay................................. 2356 public health..................... 23, 830, 2153 publication...................................... 2482 pulmonary...... 566, 594, 811, 895, 2167, 2190 pulmonary disease and toxicology... 590 pulmonary exposure......................... 192 pulmonary fibrisos............................ 540 Pulmonary Function............. 1199, 1800 pulmonary health............................ 2057 pulmonary inflammation. 186, 541, 603, 1458, 2327 pulmonary injury............................ 1190 pulmonary injury biomarkers......... 2477 Pulmonary Toxicity... 1178, 1473, 1496, 1798 Purinergic Signaling....................... 1477 PXR.................................................. 385 Pyrethroid........... 723, 1341, 2104, 2119 pyrethroid pesticide........................ 1476 pyrethroid pesticides.... 873, 1340, 1342, 2093 pyrethroids....... 1343, 1344, 1345, 1857, 2262 Pyridazine....................................... 2283 Pyriproxyfen..................................... 348 Pyrosequencing................................. 101 pyrrocidine...................................... 2428 Q-dots................................... 1197, 2184 qHTS......................................... 493, 981 qHTS data......................................... 482 qPCR............................................... 1368 QSAR...... 136, 139, 146, 157, 159, 465, 468, 483, 487, 492, 494, 496, 499, 721, 723, 861, 1812, 2464, 2538 QSAR modeling..................... 484, 1816 QSAR/QSPR.................................... 633 qsars.................................................. 849 QT prolongation............................... 195 Quality assurance............................ 2439 quantitation..................................... 1926 Quantitative behavioural assessment........................................ 780 quantitative high throughput screening......................................... 2501 Quantitative Structure Activity Relationship.................................... 1811 Quantitative structure-activity relationships QSAR................ 722, 2298 quantitative trait loci......................... 823 Quantum dot................................... 1193 quantum dot nanoparticles............. 1175, 2154, 2155 Quantum Dots............ 1197, 1465, 2168, 2183, 2184 quinolone........................................ 1076 quinone........................................... 1292 Quinones......................................... 1433 QWBA (quantitative whole body authoradiography)........................... 2257 R, R-monatin.................................. 2421 R2C................................................... 999 rabbit minipig................................. 1927 Rabbits............................................ 1630 Ractopamine................................... 2431 Rad23................................................ 306 radiation.............. 324, 1248, 2010, 2577 radio frequency radiation................ 2627 Radionuclide Decorporation........... 2291 rainbow trout.................................. 1588 Raman............................................. 1260 raoxifene......................................... 2634 RAP80............................................ 2636 Ras................................ 951, 1781, 2637 ras oncogene................................... 1783 rasH2................................................. 508 rasH2 mouse..................................... 521 RasH2 Transgenic Mice................. 2654 rat..................... 246, 512, 555, 738, 774, 1423, 2281 rat and fetal alcohol syndrome....... 2613 rat hepatocytes...................... 1107, 2242 Rat Model....................................... 1819 Rat primary Hepatocytes................ 1595 rat spleen........................................... 547 Rat Testicular cell line...................... 999 rat urinary bladder............................ 525 Rat, Rabbit........................................ 648 rats.......................................... 649, 1611 RD50............................................... 2296 RDX.................................................. 736 REACH................... 298, 470, 499, 1516 reaction chemistry.......................... 1558 reactive intermediate........................ 319 reactive metabolite.......................... 1832 Reactive Metabolites............... 154, 424, 425, 888 Reactive Orange 16.......................... 336 reactive oxygen............................... 1859 Reactive Oxygen Species........ 191, 579, 591, 1000, 1052, 1273, 1491, 1655, 1838, 2175 reactive oxygen species (ROS)....... 2560 read-across........................................ 298 Realgar.................................. 2004, 2006 ReCell............................................... 892 receptor-mediated............................. 475 receptors......... 346, 350, 367, 384, 1892 reconstituted model.......................... 975 reconstructed human skin................. 341 recruiting......................................... 2486 Red algae........................................ 1571 red blood cells................................. 1411 Redistribution ® Technology.............. 398 Redox.................................... 1299, 1349 Redox state....................................... 877 reduced intrauterine growth.............. 614 Reendothelialization....................... 1320 reference concentrations................... 502 Reference database............................... 4 reference dose....................... 1542, 1940 Reference Ranges............................. 636 Regeneration..................................... 765 regulation.................... 1727, 2376, 2695 regulation/policy............................... 996 Regulatory...................................... 2508 regulatory acceptance..................... 1309 Regulatory Developmental toxicity............................................ 1623 regulatory evolution........................ 1775 Regulatory Requirements............... 2375 regulatory T cells.......... 689, 1131, 1139 Regulatory Toxicology........ 1527, 1563, 1793 Renal............................................... 1438 renal absorption.............................. 2283 renal biomarkers............................... 754 renal drug transporter....................... 762 renal failure..................................... 1561 renal fibrosis..................................... 759 Renal Injury...................................... 748 Renal Proximal Tubule Cells.... 749, 751 renal toxicity..................................... 745 Renal Toxicology............................ 1274 Repeat Dose Studies....................... 1524 Repin................................................. 545 reporter assays................................ 2532 reproducibility................................ 1562 reproduction..... 1024, 1038, 1074, 2384, 2395, 2546 Reproduction and Development.... 1060, 2202 Reproductive..... 1029, 1030, 1050, 1059 reproductive organ.......................... 1046 Reproductive outcome.................... 1208 Reproductive Performance............. 1028 Reproductive Toxiciology.............. 1147 reproductive toxicity................... 16, 717 reproductive toxicology............ 67, 1051 reprogramming............................... 2453 reprotoxicity................................... 1231 resazurin......................................... 1904 research and job-seeking skills....... 2483 research experience for undergraduates.......................... 1873 residues........................................... 2119 resorufin.......................................... 1904 Respiratory...... 1196, 1914, 1920, 1921, 2476 respiratory allergen........................... 907 Respiratory allergy..................... 84, 903 respiratory effects............................. 611 Respiratory epithelium......... 2329, 2480 respiratory sensitization........ 90, 97, 905 Respiratory thoracic impedance....... 576 respiratory toxicity..... 1555, 2029, 2041, 2474, 2478 respiratory tract.... 595, 889, 2290, 2475, 2478, 2479 Respiratory, lung............................. 2474 Restenosis....................................... 1320 Resume preparation........................ 2485 resveratrol........... 741, 1670, 2227, 2321 Retailers.......................................... 2115 retinoic acid................ 1506, 2088, 2369 retinol.................................................. 74 Retinopathy of prematurity............. 2587 retrotransposons.................................. 99 r-H2AX............................................. 118 Rhabdomyosarcoma and canine cancers................................... 955 rhinitis................................................. 97 Rhinovirus...................................... 1289 Ribbon worm.................................. 2430 Ribosomal RNA Cleavage.............. 1662 Ribosome...................................... 34, 38 Ribosome inactivating protein............ 39 ribosome-inactivating protein......... 2414 Ribosome-inactivating stress............ 370 Ribosomes.......................................... 39 ribotoxic stress.................. 35, 36, 37, 39 ricin................... 2017, 2223, 2432, 2433 right whale...................................... 2405 Rip1.................................................. 308 risk..................... 367, 1263, 1535, 1936, 2694, 2699 Risk and Safety Assessment........... 2630 Risk Assessment.................. 2, 8, 11, 13, 47, 48, 49, 52, 154, 332, 471, 476, 480, 483, 485, 489, 500, 501, 502, 586, 701, 703, 704, 705, 712, 720, 830, 848, 851, 862, 904, 916, 921, 925, 931, 1251, 1346, 1424, 1529, 1530, 1531, 1532, 1534, 1536, 1537, 1543, 1545, 1554, 1568, 1569, 1576, 1581, 1701, 1715, 1717, 1728, 1732, 1733, 1767, 1797, 1799, 1805, 1813, 1877, 1933, 1934, 1937, 1939, 1955, 1963, 1964, 1965, 2106, 2286, 2289, 2296, 2307, 2308, 2309, 2438, 2456, 2457, 2459, 2460, 2462, 2538, 2573, 2682, 2688, 2689, 2690, 2691, 2692 Risk Assessment Methods.............. 1938 Risk Characterization..................... 1680 risk communication.......................... 933 risk exposure................................... 2431 risk management................... 1517, 2153 risk versus benefits......................... 1796 rituximab........................................... 661 Rivers.............................................. 2403 RNAi....................................... 522, 1861 rodent chow diet............................. 1062 Rodent Study.................................. 1909 rodents.................................... 519, 2614 ROS.... 220, 415, 753, 1668, 2003, 2070 rotenone.......................................... 1900 RT-PCR arrays................................ 1583 RUNX2........................................... 2217 rural population.............................. 1209 Ryanodine....................................... 2623 Ryanodine receptor............... 2246, 2624 S-(1, 2-Dichlorovinyl)-L-cysteine sulfoxide........................................... 755 S100A4/7........................................ 2649 S1P.................................................. 1892 safer alternatives............... 911, 912, 913 Safety............. 10, 558, 811, 1765, 2428, 2437, 2439 Safety Assessment... 651, 742, 782, 783, 790, 808, 1060, 1317, 1318, 1319, 1323, 1541, 1561, 1892, 1896, 1911, 1916, 1925, 2440, 2441 398 SOT 50th Anniversary Annual Meeting
Society of Toxicology 2011 Abstract Key Word Index (Continued) The numerals following each key word refer to the relevant abstract number(s). safety assessment: non-phamaceutical............................................ 1560 safety biomarker............................... 124 safety evaluation............. 467, 491, 1552 Safety Pharmacology........... 3, 201, 852, 1724, 2468, 2469, 2471 Safety testing............................ 11, 2684 Salmonella mutagenicity assay......... 336 Salmonella/microsome mutagenicity assay.......................... 1409 sandwich-cultured hepatocytes....... 1081 SAR................................................ 1965 Sarcocysis. fayeri............................ 1211 sarin...................................... 1334, 2035 SAS................................................... 490 SBDP-145....................................... 1443 school.............................................. 1546 Science and Decisions.................... 1962 science outreach.............................. 1866 Science Policy...................... 1484, 2508 Scopolamine............... 1646, 2016, 2041 Screening..................... 867, 1523, 1910, 2452, 2675 screening assays.............................. 2367 screening levels................................ 863 Sculpin............................................ 2386 SDF-1b........................................... 1664 Seafood........................................... 1974 seafood safety................................. 1963 Secondhand Smoke.............. 1253, 1254 secondhand tobacco smoke.............. 834 segmental duplication..................... 1770 Seizure.................................... 399, 1742 seizures... 1804, 1806, 1807, 1808, 2020 Selection......................................... 1675 Selenium....................... 311, 1398, 2249 Semicarbazide................................... 627 senescence...................................... 1764 senna................................................. 235 sennosides......................................... 235 sensitive populations........................ 472 sepiapterin reductase...................... 1399 Serine hydrolases............................ 1336 serine protease inhibitor................. 2364 serotonin......................... 346, 964, 1881 serotonin transporter gene.............. 1363 SERT............................................... 1829 Sertoli cell........................................... 66 serum.................................... 1023, 2562 sex................................................... 2492 sex differences................................ 2600 sexual development........................ 1071 sexual differentiation.......................... 20 sexual dimorphism.................... 266, 396 sexual maturity............................... 1923 SHE cell transformation................. 1528 SHetA2........................................... 1885 Shiga toxins.............................. 37, 2414 Shipping.......................................... 1431 short time exposure......................... 1001 Short-term health effects.................. 829 Sick Building Syndrome................. 1573 Sick-building Syndrome................. 1225 signal transduction.......... 400, 937, 2314 Signaling Pathways................ 328, 1891 Signature........................................... 876 SILAC............................................... 970 silica...................................... 2083, 2173 silica nanoparticles............... 2053, 2085 siloxanes........................................... 700 Silver..................................... 1759, 2181 Silver nanoparticle................ 1762, 1763 Silver Nanoparticles............ 1456, 1467, 1758, 1761, 2063, 2064, 2067, 2071, 2075, 2079 Similarity Ensemble Approach......... 854 single cell toxicity........................... 1234 single nucleotide polymorphism.... 1365, 1366, 1371 single walled carbon nanotubes.......... 59 siRNA,.............................................. 553 Sirt 1................................................. 414 Sirt1................................................ 2499 Size................................................. 2065 skeletal muscle................................ 1451 skeletal muscle toxicity.................. 1589 skills................................................ 2481 skin............ 83, 508, 543, 544, 632, 637, 641, 642, 1006, 1750, 1751, 1780, 1781, 1782, 1993, 2026, 2030, 2072, 2554 skin absorption.................................. 634 skin carcinogenesis.......... 222, 237, 958, 1783, 1784 skin cells........................................... 639 Skin corrosion................................... 646 skin inflammation................. 1783, 2574 Skin injury............................ 1756, 2013 Skin irritation.............. 91, 469, 645, 646 skin model...................................... 1005 skin penetration.......... 1107, 2154, 2155 skin permeability.............................. 633 skin rash...................... 1364, 1501, 1505 skin sensitization... 86, 90, 91, 465, 967, 974, 978, 1000, 1002, 1009, 1010, 2513, 2527, 2536, 2551 skin sensitization assay....................... 88 skin substitute................................... 892 skin toxicity.............................. 965, 966 skin tumorigenesis............................ 954 small Maf proteins.......................... 2127 small scale inhalation studies........... 577 Smoke............................................... 592 smoke inhalation............................... 567 Smokeless Tobacco......................... 1558 smoking.......................................... 1287 smoking cessation........................... 1363 Smooth muscle of trachea.............. 1456 S-nitrosylation.................................. 257 social anxiety disorder...................... 802 Social Media..................................... 419 society............................................. 1880 SOD.................................................. 165 sodium.............................................. 203 Sodium channel...................... 170, 1341 sodium channels................... 1343, 1353 soft electrophiles............... 503, 504, 505 Soil.......................................... 526, 1265 Soil Dust........................................... 670 Soil Ingestion.................................. 2572 solute carrier transporter (SLC)...... 1597 Solutol............................................... 781 solvent neurotoxicity...................... 1575 soman.......................... 2020, 2034, 2039 Sp proteins........................................ 956 Sp Transcription factors............ 226, 955 SP1.................................................. 1858 species differences.......................... 2100 Specificity Protein............................ 384 Specificity protein transcription factors............................................... 956 Specificity proteins........................... 220 spectroscopy................................... 2312 sperm count.................................... 2230 sperm whale.................................... 2405 sperm whales.................................. 2252 Spermatogenesis................................. 63 sphinganine 1-phosphate................ 1448 Sphingolipids.................................... 241 Spirulina......................................... 2436 spleen................................................ 112 spleen lymphocytes........................ 1411 splenocytes..................................... 2364 Splenotoxity...................................... 390 Splice Variants.................................. 375 Sprague-Dawley Rat....................... 1028 Sprague-Dawley rats.............. 531, 2075 SPRAYERS.................................... 2116 Spring Valley.................................... 928 ST depression................................... 570 Stability........................................... 1431 stable isotope dilution tandem mass spectrometry.......................... 1681 startle response............................... 2617 STAT1alpha...................................... 403 STAT3....................................... 441, 956 static diffusion cell............................ 634 statin................................................. 789 statistical association...................... 2594 Statistics.................................... 134, 727 status epilepticus............................. 2039 steatogenic hepatotoxicity.............. 1118 steatohepatitis................................. 1114 Steatosis................................ 1958, 2586 Stem cell...... 74, 894, 1155, 1171, 1992, 1993, 2450 Stem Cell-derived Cardiomyocytes.............................. 1894 Stem cells......... 14, 68, 72, 79, 890, 891, 895, 982, 1159, 1166, 2451, 2452, 2665, 2677 Stent................................................ 1320 stereology....................................... 1348 Steroid hormones............................ 1436 steroid pathway................................. 999 Steroidogenesis.......... 1037, 1039, 1041, 1048, 2352, 2368, 2383, 2547, 2549 Steroids........................................... 2135 stochastic gene expression................ 123 Store-operated calcium channels.... 1672 S-transalkylation............................. 1305 StrataTest.......................................... 647 stress............................. 165, 1205, 2151 Stress Response.................................. 34 stress response mutant.................... 1467 stress test........................................... 608 striatum............................................. 506 Strombus gigas (conch).................. 1068 Structural Alerts................................ 154 Structure........................................... 857 Structure activity relationships......... 468 Structure Activity Relationships (SAR)...................... 141, 488, 860, 1595 structure bioactivity relationship.... 1800 structure-activity............................. 1967 structure-activity relationships... 75, 936 Styrene............. 1199, 1226, 1359, 1530, 1860, 2643 subcellular localization................... 2300 subchronic toxicity......................... 2421 subchronic toxicology.................... 1918 Subcutaneous.................................... 618 subretinal.......................................... 524 substrate-competitive........................ 401 Substructure Identification............... 153 suicidality....................................... 1541 sulfolane......................................... 1542 sulforaphane........................... 460, 2638 Sulfotransferase.............................. 1862 Sulfur donors.................................. 2046 Sulfur Mustard................. 114, 544, 641, 1748, 1749, 1752, 1753, 1754, 1755, 1756, 2013, 2019, 2026, 2027, 2028, 2030, 2036, 2040 Sulfuryl Fluoride............................ 2100 SULT1A1........................................ 1368 Sunitinib......................................... 1159 Superantigen................................... 1512 Superfund............................... 323, 1675 Surface cleanup................................ 863 surfactant protein-D.......................... 257 surfactants....................................... 1526 Surgery.............................................. 270 surgical glove.................................. 1557 Surrogate......................................... 1965 survival........................................... 1361 susceptibility......... 271, 819, 1337, 1338 susceptibility biomarkers................ 2112 susceptible populations................... 2461 Suspension Cells............................... 316 sustainable........................ 908, 909, 910 SW-480........................................... 2233 SWCNT.......................................... 1179 Swedish snus.................................. 1198 Swine................................................ 526 synaptic plasticity........................... 2625 synaptogenesis................................ 2620 synchrotron..................................... 1633 Synergy........................................... 2306 Synoviocytes..................................... 362 Synthetic Tandem Repeat Promoter screening......................... 1703 System biology................................. 481 Systemic Dose................................ 2107 systemic toxicity................... 1312, 1549 Systems biology........... 9, 135, 366, 937, 1721, 1734, 1736, 1737, 1739 Systems Toxicology.............. 1593, 1739 T cell......................................... 687, 694 T cell independent antibody response............................................ 649 T cell subsets...................................... 93 Tacrolimus...................................... 2284 Tai Chi............................................ 2204 TAM-DNA adducts......................... 2656 Tamoxifen............................... 428, 2656 TARC.............................................. 2209 Target Safety............................. 125, 522 Taurine........................ 1271, 2583, 2584 TCCD............................................. 1704 TCDD........................ 78, 197, 198, 213, 654, 709, 1091, 1122, 1123, 1128, 1135, 1137, 1584, 1588, 1624, 1647, 1684, 1777 TCP................................................. 1692 TD50................................................. 487 TDAR....................................... 660, 664 teeth................................................ 1237 Telemetry.............. 562, 568, 1919, 1920 tellurium tetrachloride...................... 302 Telomere........................................... 121 Telomeres....................................... 2251 temperature..................................... 2381 Tempol.............................................. 961 TEQ...................................... 1959, 1961 teratogen............................... 1610, 2506 teratogenesis................................... 1045 teratogenicity...................................... 75 Teratology....................................... 1617 terpenes........................................... 2154 testes........................... 1022, 1041, 1048 testicular toxicity................................ 69 testis...................... 64, 1441, 2084, 2191 Testosterone................ 1032, 1039, 2088 Testosterone proprionate................. 2189 tetrabromobisphenol A.......... 1056, 2246 Tetrachloroethylene........................ 2641 tetrahydrouridine.............................. 799 tetrazolate....................................... 1544 Tetrodotoxin................................... 2430 Text Mining...................................... 728 Tg2576 mice................................... 1331 TGFbeta............................................ 222 TGF-beta........................................... 687 Th17................................................ 1506 Th17 cells....................................... 1501 Thalidomide...................................... 839 Therapeutic Antibody..................... 1891 therapy............................................ 1790 Thermodynamics-Based Partition Index............................................... 1815 Thermoluminescence...................... 2385 Thiabendazole................................. 1821 thiazolidinedione.............................. 422 Thioarsenates.................................. 1162 Thiols-Redox.................................. 2336 thioredoxin.................................. 95, 877 thioredoxin reductase.............. 458, 1663 THP-1............................................... 966 THPI............................................... 2278 Threshold.......................................... 477 Key Word Index up-to-date information at www.toxicology.org 399
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50 th Anniversary Annual Meeting &
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Scientific Program Overview A page
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9:00 AM-12:30 PM POSTER SESSionS
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March 6-10, 2011 Walter E. Washingt
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Celebration Activities Historical H
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of the Society Regional Chapter Yea
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SOT Presidents 1961-2011 1966 1967
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The SOT Council Thanks and Recogniz
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of the Past 50 Years 2003 Michael D
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Thank You to the following individu
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SOT Celebration Event Floor Plan Ba
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50 th Anniversary Annual Meeting an
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Toxicological Sciences The Official
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Society of Toxicology 2011 Walter E
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Society of Toxicology 2011 Washingt
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2011 SOT 50 th Anniversary Featured
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Society of Toxicology 2011 Washingt
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Society of Toxicology 2011 ToxExpo
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Creating a Safer and Healthier Worl
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Society of Toxicology 2011 General
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SOT Job Bank YOUR RECRUITMENT AND E
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Society of Toxicology 2011 SOT 2011
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Society of Toxicology 2011 Recognit
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Society of Toxicology 2011 Recognit
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Society of Toxicology 2011 RC, SIG,
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Society of Toxicology 2011 Student
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Society of Toxicology 2011 Outreach
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