Program - Society of Toxicology

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50 th Anniversary Annual Meeting and ToxExpo Program Description (Continued) Tuesday Abstract # Abstract # #1113 Poster Board Number.....................................441 NRF2 ACTIVATION PROMOTES HYPERCHOLESTEROLEMIA AND GALLSTONE FORMATION. M. A. Paranjpe 1 , Q. Cheng 1 , J. Moscovitz 1 , D. Ajay 1 , M. Yamamoto 2 and A. Slitt 1 . 1 Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, RI and 2 Medical Biochemistry, Tohoku University, Sendai, Miyagi, Japan. #1114 Poster Board Number.....................................442 NRF2 PROTECTS MOUSE LIVER FROM OXIDATIVE INJURY AND STEATOHEPATITIS INDUCED BY PERSISTENT ACTIVATION OF AHR. H. Lu and C. D. Klaassen. University of Kansas Medical Center, Kansas City, KS. #1115 Poster Board Number.....................................443 TCDD EFFECTS ON HEPATIC LIPID COMPOSITION IN MICE. M. M. Angrish 1,2 , B. D. Mets 2,3 , D. Wright 3 and T. R. Zacharewski 1,2,3 . 1 Genetics Program, Michigan State University, East Lansing, MI, 2 Center for Integrative Toxicology, Michigan State University, East Lansing, MI and 3 Biochemistry & Molecular Biology, Michigan State University, East Lansing, MI. #1116 Poster Board Number.....................................444 PHARMACOLOGIC NRF2 ACTIVATION PROMOTES HYPERCHOLESTEROLEMIA IN MICE. J. Moscovitz, M. Paranjpe and A. Slitt. University of Rhode Island, Kingston, RI. #1117 Poster Board Number.....................................445 BERBERINE INDUCES HEPATIC STEATOSIS VIA C/EBPβ ACTIVATION. B. Lee 1 , Y. Choi 1 , H. Suh 1 , S. Jeoung 1 and K. Lee 2 . 1 Seoul National University, Seoul, Republic of Korea and 2 Sungkyunkwan University, Suwon, Republic of Korea. #1118 Poster Board Number.....................................446 EFFECTS OF MEDICINAL HERBS AND THEIR COMPONENTS ON THE STEATOGENIC HEPATOTOXICITY. Y. Choi 1 , S. Jeoung 1 , H. Suh 1 , H. Choi 1 , S. Park 1 , S. Oh 1 , J. Choi 2 , S. Lee 3 , K. Lee 4 and B. Lee 1 . 1 Seoul National University, Seoul, Republic of Korea, 2 Pukyong National University, Pusan, Republic of Korea, 3 Yeungnam University, Gyeongbuk, Republic of Korea and 4 Sungkyunkwan University, Suwon, Republic of Korea. #1119 Poster Board Number.....................................447 FIBRINOGEN DEFICIENCY INCREASES LIVER INJURY AND EARLY GROWTH RESPONSE-1 EXPRESSION IN A MODEL OF CHRONIC XENOBIOTIC-INDUCED CHOLESTASIS. J. P. Luyendyk 1 , K. M. Kassel 1 , K. Allen 1 , G. L. Guo 1 , G. Li 1 , G. H. Cantor 2 and B. L. Copple 1 . 1 Pharmacology, Toxicology, and Therapeutics, The University of Kansas Medical Center, Kansas City, KS and 2 Discovery Toxicology, Bristol-Myers Squibb, Princeton, NJ. #1120 Poster Board Number.....................................448 ENDOGENOUS CYP1B1 METABOLISM IN VIVO CONTROLS ENDOGENOUS LIVER PPAR ACTIVITY WITHOUT EXPRESSION IN HEPATOCYTES. J. R. Bushkofsky 1,2 , M. L. Larsen 3 , S. Wang 3 and C. R. Jefcoate 1,2,3 . 1 Endocrinology and Reproductive Physiology, University of Wisconsin Madison School of Medicine and Public Health, Madison, WI, 2 Molecular and Environmental Toxicology Center, University of Wisconsin Madison, Madison, WI and 3 Department of Pharmacology, University of Wisconsin Madison, Madison, WI. Tuesday Morning, March 8 9:00 AM to 12:30 PM Exhibit Hall Poster Session: Ah Receptor in Immune Regulation and Toxicity Chairperson(s): Qing Li, Nippon Medical School, Tokyo, Japan. Displayed: 9:00 AM–12:30 PM Author Attended: 9:00 AM–11:00 AM #1121 Poster Board Number.....................................501 EVIDENCE OF AhR-DEPENDENT SUPPRESSION OF IMMUNOGLOBULIN EXPRESSION. M. J. Wourms and C. Sulentic. Pharmacology and Toxicology, Boonshoft School of Medicine Wright State University, Dayton, OH. #1122 Poster Board Number.....................................502 TCDD-INDUCED MODULATION OF THE hs1, 2 ENHANCER WITHIN THE 3’IgHRR IN MOUSE AND HUMAN. J. Liu, T. Fernando, S. Ochs and C. E. Sulentic. Pharmacology and Toxicology, Boonshoft School of Medicine, Wright State Unversity, Dayton, OH. #1123 Poster Board Number.....................................503 PAX5 MAY MEDIATE TCDD-INDUCED DIFFERENCES IN TRANSCRIPTIONAL REGULATION OF THE MOUSE AND HUMAN hs1, 2 ENHANCER. S. Ochs, J. Liu and C. Sulentic. Pharmacology and Toxicology, Wright State Unversity, Dayton, OH. #1124 Poster Board Number.....................................504 ROLE OF THE 3’IgHRR IN TCDD- INDUCED SUPPRESSION OF THE IMMUNOGLOBULIN HEAVY CHAIN. J. L. Panchal, E. Romer, T. Fernando and C. Sulentic. Pharmacology and Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, OH. #1125 Poster Board Number.....................................505 NF-B/REL AND THE AhR IN MODULATING THE 3́IgHRR. R. Salisbury and C. Sulentic. Pharmacology and Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, OH. #1126 Poster Board Number.....................................506 PERSISTENT DEVELOPMENTAL ARYLHYDROCARBON RECEPTOR ACTIVATION MODULATES NOTCH1- DEPENDENT T-CELL BUT NOT B-CELL DIFFERENTIATION POTENTIAL. L. Ahrenhoerster, P. Lakatos and M. Laiosa. School of Public Health, University of Wisconsin Milwaukee, Milwaukee, WI. 214 Education-Career Development Sessions Exhibitor Hosted Sessions Featured Sessions Historical Highlights Informational Sessions Platform Sessions
Society of Toxicology 2011 Program Description (Continued) Abstract # #1127 Poster Board Number.....................................507 THE ROLE OF THE ARYL HYDROCARBON RECEPTOR IN WOOD SMOKE-INDUCED MACROPHAGE SUPPRESSION. C. T. Migliaccio, E. Kobos, V. Porter and T. Ward. Center for Environmental Health Sciences, University of Montana, Missoula, MT. #1128 Poster Board Number.....................................508 TCDD TREATMENT ENHANCES THE M1 PHENOTYPE IN J774 MURINE MACROPHAGES. A. E. McCartney, R. A. Aguayo, P. V. Hamilton and K. A. Mitchell. Biological Sciences, Boise State University, Boise, ID. #1129 Poster Board Number.....................................509 THE ARYL HYDROCARBON RECEPTOR MODULATES PHENOTYPE AND FUNCTION OF DENDRITIC CELLS. G. Jin and B. Lawrence. Environmental Medicine, University of Rochester, Rochester, NY. #1130 Poster Board Number.....................................510 MODULATION OF NF-KB MEDIATED DENDRITIC CELL DIFFERENTIATION AND FUNCTION BY ARYL HYDROCARBON RECEPTOR ACTIVATION. C. Vogel 1,3 , S. Goth 2 , D. Wu 3 , V. Kou 3 , A. Lollies 3 , I. Pessah 2 and F. Matsumura 1,3 . 1 Environmental Toxicology, University of California, Davis, CA, 2 Molecular Biosciences, University of California, Davis, CA and 3 Center for Health and the Environment, University of California, Davis, CA. #1131 Poster Board Number.....................................511 AH RECEPTOR ACTIVATION GENERATES REGULATORY DENDRITIC CELLS CAPABLE OF INDUCING CD4+ CD25+ FOXP3+ REGULATORY T CELLS. T. Simones, J. Bankoti and D. M. Shepherd. Center for Environmental Health Sciences, University of Montana, Missoula, MT. #1132 Poster Board Number.....................................512 ALL AHR LIGANDS ARE NOT CREATED EQUAL: THE DURATION OF AHR ACTIVATION IS A KEY PARAMETER IN MODULATING THE IMMUNE RESPONSE TO INFLUENZA VIRUS INFECTION. J. Head 1 and B. Lawrence 1,2 . 1 Environmental Medicine, University of Rochester, Rochester, NY and 2 Microbiology and Immunology, University of Rochester, Rochester, NY. #1133 Poster Board Number.....................................513 TCDD AMELIORATES COLITIS IN MICE BY INDUCTION OF REGULATORY T CELLS (TREGS) VIA AHR ACTIVATION. N. P. Singh 1 , U. Singh 1 , B. Singh 2 , L. Hofseth 3 , M. Nagarkatti 1 and P. Nagarkatti 1 . 1 Pathology, Microbiology, and Immunology, University of South Carolina School of Medicine, Columbia, SC, 2 Primate Research Center, Emory University, Atlanta, GA and 3 South Carolina College of Pharmacy, University of South Carolina, Columbia, SC. #1134 Poster Board Number.....................................514 ARYL HYDROCARBON RECEPTOR ACTIVATION SUPPRESSES INTESTINAL INFLAMMATION. J. M. Benson and D. M. Shepherd. Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, MT. Abstract # #1135 Poster Board Number.....................................515 BACH2 BINDING TO Prdm1 AS A MECHANISM OF 2, 3, 7, 8-TETRACHLORODIBENZO-P- DIOXIN(TCDD)-MEDIATED IMMUNE SUPPRESSION. A. S. Phadnis 1,3 , K. DeAbrew 4 , R. S. Thomas 4 and N. E. Kaminski 2,3 . 1 Genetics Program, Michigan State University, East Lansing, MI, 2 Pharmacology & Toxicology, Michigan State University, East Lansing, MI, 3 Center for Integrative Toxicology, Michigan State University, East Lansing, MI and 4 Hamner Institutes for Health Sciences, Research Triangle Park, NC. #1136 Poster Board Number.....................................516 DIDOX (DIHYDROXYBENZOHYDROXAMIC ACID) AMELIORATES MACROPHAGE AHR ACTIVATION, CYP1A1/AHR INDUCTION, AND OXIDATIVE STRESS PROFILES INDUCED BY PCB-126. C. D. Rice, V. S. Gallichio and T. M. Matsebatlela. Biological Sciences, Clemson University, Clemson, SC. #1137 Poster Board Number.....................................517 MECHANISTIC INVESTIGATION OF TCDD EFFECTS ON CD40 LIGAND-INDUCED ACTIVATION OF PRIMARY HUMAN B CELLS: PERTURBATION OF IMMEDIATE AND PERSISTENT SIGNALING. H. Lu 1,2 , R. Crawford 1,2 and N. E. Kaminski 1,2 . 1 Center for Integrative Toxicology, Michigan State University, East Lansing, MI and 2 Pharmacology & Toxicology, Michigan State University, East Lansing, MI. #1138 Poster Board Number.....................................518 AH RECEPTOR MEDIATED RESTORATION OF SPLEEN AND BONE MARROW FOLLOWING THE CYP1B1-DEPENDENT ADVERSE EFFECTS OF POLYCYCLIC AROMATIC HYDROCARBONS (PAHS). A. U. N’jai 1,3 , M. Larsen 2 , C. R. Jefcoate 2,3 and C. J. Czuprynski 1,3,4 . 1 Pathobiological Sciences, University of Wisconsin Madison, Madison, WI, 2 Pharmacology, University of Wisconsin Madison, Madison, WI, 3 METC, University of Wisconsin Madison, Madison, WI and 4 Food Research Institute, University of Wisconsin Madison, Madison, WI. #1139 Poster Board Number.....................................519 ACTIVATION OF THE ARYL HYDROCARBON RECEPTOR BY TCDD SUPPRESSES SENSITIZATION IN A MOUSE PEANUT ALLERGY MODEL. V. J. Schulz 1 , J. Smit 1,2 , L. Boon 3 , M. van den Berg 1 , M. van Duursen 1 and R. Pieters 1 . 1 Immunotoxicology, Institute of Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands, 2 Utrecht Center for Food Allergy, Utrecht, Netherlands and 3 Bioceros B.V., Utrecht, Netherlands. Tuesday Poster Sessions Regional Interest Session Roundtable Sessions Symposium Sessions Thematic Sessions Workshop Sessions 215
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50 th Anniversary Annual Meeting &
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Scientific Program Overview A page
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9:00 AM-12:30 PM POSTER SESSionS
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March 6-10, 2011 Walter E. Washingt
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Celebration Activities Historical H
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of the Society Regional Chapter Yea
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SOT Presidents 1961-2011 1966 1967
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The SOT Council Thanks and Recogniz
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of the Past 50 Years 2003 Michael D
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Thank You to the following individu
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SOT Celebration Event Floor Plan Ba
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50 th Anniversary Annual Meeting an
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Toxicological Sciences The Official
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Society of Toxicology 2011 Walter E
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Society of Toxicology 2011 Washingt
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2011 SOT 50 th Anniversary Featured
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Society of Toxicology 2011 Washingt
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Society of Toxicology 2011 ToxExpo
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Society of Toxicology 2011 Exhibito
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Creating a Safer and Healthier Worl
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Society of Toxicology 2011 General
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SOT Job Bank YOUR RECRUITMENT AND E
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Society of Toxicology 2011 SOT 2011
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Society of Toxicology 2011 2011 Awa
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Endowment Awardees for SOT’s 50 t
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Society of Toxicology 2011 Recognit
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Society of Toxicology 2011 Recognit
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Society of Toxicology 2011 RC, SIG,
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Society of Toxicology 2011 Student
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Society of Toxicology 2011 Outreach
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Society of Toxicology 2011 Satellit
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Society of Toxicology 2011 Program
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Society of Toxicology 2011 Author I
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Society of Toxicology 2011 Abstract
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Society of Toxicology 2011 2010-201
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Society of Toxicology 2011 Elected
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Society of Toxicology 2011 Elected
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Society of Toxicology 2011 Endowmen
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Society of Toxicology 2011 SOT Affi
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