Program - Society of Toxicology

50 th Anniversary Annual Meeting and ToxExpo
Program Description (Continued)
MONday
Abstract # Abstract #
#391 Poster Board Number.....................................812
ENHANCED PDE4B EXPRESSION
AUGMENTS LPS-INDUCIBLE TNF-α
IN GLUCOSE-PRIMED MONOCYTES:
A POTENTIAL PATHOGENIC ROLE
FOR PHOSPHODIESTERASES (PDES)
IN THE DEVELOPMENT OF DIABETIC
COMPLICATIONS. ​E. Chambers 1 , L.
Gobejishvili 1 , S. Joshi-Barve 1 , C. McClain 1,2 and S.
Barve 1 . 1 Department of Medicine/GI, University of
Louisville, Louisville, KY and 2 Robley Rex Veterans
Administration Medical Center, Louisville, KY.
#392 Poster Board Number.....................................813
CURCUMIN EPIGENETICALLY
REACTIVATES SILENCED TUMOR
SUPPRESSOR GENE - TISSUE FACTOR
PATHWAY INHIBITOR-2 AND DECREASES
CELL SURVIVAL AND INVASIVENESS IN
HEPATOCELLULAR CARCINOMA CELLS. ​
A. Moghe 1 , A. S. Barve 1 , D. Barker 1 , S. Ghare 1 , L.
Gobejishvili 1 , S. Joshi-Barve 1 , C. McClain 1,2 and S.
Barve 1 . 1 Department of Medicine/GI, University of
Louisville, Louisville, KY and 2 Robley Rex Veterans
Administration Medical Center, Louisville, KY.
#393 Poster Board Number.....................................814
THE HEPATOCYTE AUTONOMOUS CLOCK
MODULATES THE CHRONOTOXICITY OF
ACETAMINOPHEN. ​B. P. Johnson 1 , J. Walisser 1 ,
Y. Liu 1 , A. Shen 1 , E. McDearmon 2 , B. McIntosh 2 , A.
Schook 2 , J. Takahashi 2 and C. Bradfield 1 . 1 Oncology,
University of Wisconsin Madison, Madison, WI and
2
Northwestern University, Evanston, IL.
#394 Poster Board Number.....................................815
ARSENITE EXPOSURE DOWN-REGULATES
GLUTAMATE TRANSPORTER EXPRESSION
IN GLIAL CELLS. ​Y. Castro-Coronel 1,2 , A.
Ortega 1 , L. Del Razo 2 and E. Lopez-Bayghen 1 .
1
Department Genetica y Biol.Mol., CINVESTAV,
México, Mexico and 2 Department Toxicología,
CINVESTAV, México, Mexico.
#395 Poster Board Number.....................................816
DOWN-REGULATION OF TWO HSP
FAMILIES BY TNIP1 IN HACAT
KERATINOCYTES. ​V. P. Ramirez, C. Zhang,
W. Krueger and B. J. Aneskievich. Department
of Pharmaceutical Sciences, School of Pharmacy,
University of Connecticut, Storrs, CT.
#396 Poster Board Number.....................................817
SEXUALLY DIMORPHIC ROLE FOR THE
CIRCADIAN CLOCK IN MODULATING
XENOBIOTIC METABOLISM. ​L. A.
Hooven, K. Sherman, E. Chow, L. Beaver and J.
Giebultowicz. Oregon State University, Corvallis,
OR.
#397 Poster Board Number.....................................818
CHARACTERIZATION OF THE
PROMOTER-PROXIMAL REGION OF
HUMAN MULTIDRUG RESISTANCE-
ASSOCIATED PROTEIN 4 GENE. ​J. E.
Manautou and X. Gu. Pharmaceutical Sciences,
University of Connecticut, Storrs, CT.
#398 Poster Board Number.....................................819
HIGH CONTENT ANALYSIS USING
REDISTRIBUTION® TECHNOLOGY. ​A.
M. Peters, D. Miller, B. Samson and Y. Fedorov.
Life Science Research - Cellomics, Thermo Fisher
Scientific, Pittsburgh, PA. Sponsor: J. Haskins.
#399 Poster Board Number.....................................820
ASSESSMENT OF NUCLEAR FACTOR
KAPPA B (NF-κB) SIGNALING IN THE
HIPPOCAMPUS DURING KANIC ACID
EXPOSURE USING TRANSGENIC
REPORTER MICE. ​J. A. Miller 1 , R. A. Bialecki 2
and R. B. Tjalkens 1 . 1 Center for Environmental
Medicine, Colorado State University, Fort Collins,
CO and 2 Safety Assessment U.S., AstraZeneca,
Wilmington, DE.
#400 Poster Board Number.....................................821
ALTERATIONS OF SIGNALING PROTEIN
INTERACTIONS IN RESPONSE TO
INCREASING DOSE. ​C. Kinzer, H. Williams, X.
Gao, N. Rubenstein, A. Cook, J. Vrana and J. Boyd.
Bennett Department of Chemistry, West Virginia
University, Morgantown, WV.
#401 Poster Board Number.....................................822
IMPACT OF ENERGY METABOLISM ON
THE DESIGN OF KINASE-TARGETED
THERAPEUTICS. ​A. Cook, H. Williams, X. Gao
and J. Boyd. Bennett Department of Chemistry, West
Virginia University, Morgantown, WV.
#402 Poster Board Number.....................................823
cAMP-DEPENDENT PATHWAY(S)
INCREASE P27 KIP -CYCLIN D1 THROUGH
THE RAP-GTP/B-RAF MAPK SIGNALING
PATHWAY IN RENAL CANCER. ​N.
Mastrandrea, K. Y. Tham, J. D. Cohen, T. J. Monks
and S. S. Lau. Pharmacology/Toxicology, University
of Arizona, Tucson, AZ.
#403 Poster Board Number.....................................824
EFFECT OF P, P’-DDE ON JAK2,
STAT1α, AND NFκB ACTIVATION IN
MACROPHAGES J774A.1. ​N. A. Torres-
Aviles 1 , L. C. Acosta-Saavedra 1 , A. L. Luna 1 , E. K.
Silbergeld 2 and E. S. Calderon-Aranda 1 . 1 Department
of Toxicologia, Cinvestav, Mexico, Mexico and
2
BSPH, Johns Hopkins University, Baltimore, MD.
#404 Poster Board Number.....................................825
A ROLE FOR STRESS-RESPONSIVE
SIGNALING IN THE REGULATION OF ERK
OSCILLATIONS. ​T. J. Weber 1 , H. Shankaran 2 , K.
M. Waters 2 , W. B. Chrisler 1 and R. L. Sontag 1 . 1 Cell
Biology & Biochemistry, PNNL, Richland, WA and
2
Computational Biology, PNNL, Richland, WA.
#405 Poster Board Number.....................................826
HARMINE MODULATES DIOXIN-
INDUCED CYP1A1 ENZYME THROUGH
TRANSCRIPTIONAL AND POST
TRANSLATIONAL MECHANISMS. ​M. El
Gendy and A. El-Kadi. Faculty of Pharmacy and
Pharmaceutical Sciences, University of Alberta,
Edmonton, AB, Canada.
148
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