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50 th Anniversary Annual Meeting and ToxExpo Program Description (Continued) Wednesday Abstract # Abstract # #1998 Poster Board Number.....................................531 INORGANIC ARSENIC CAUSES APOPTOSIS IN MOUSE CEREBRUM THROUGH AN OXIDATIVE STRESS-INDUCED MAPKS AND ER STRESS PATHWAY. C. Huang 1 , M. Lee 2 , Y. Chen 3 , T. Ho 1 , C. Yen 4 and C. Su 5 . 1 School of Chinese Medicine, China Medical University, Taichung, Taiwan, 2 Department of Surgery, Penghu Hospital, Department of Health, Executive Yuan, Penghu, Taiwan, 3 Department of Physiology, China Medical University, Taichung, Taiwan, 4 Department of Occupational Safety and Health, Chung Shan Medical University, Taichung, Taiwan and 5 Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, Changhua, Taiwan. #1999 Poster Board Number.....................................532 ALTERED EXPRESSION PROFILES OF microRNAs UPON ARSENIC EXPOSURE OF HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS. Y. Wei 1 , Y. Shi 2 , X. Ma 3 and R. Li 2 . 1 Department of Community Medicine, Mercer University School of Medicine, Macon, GA, 2 Key Laboratory of Pathobiology, Jilin University, Changchun, Jilin, China and 3 Department of Molecular and Cell Biology, Center for Systems Biology, University of Texas at Dallas, Richardson, TX. #2000 Poster Board Number.....................................533 ARSENIC INDUCES EXPRESSION OF C-REACTIVE PROTEIN. I. Druwe, J. J. Sollome, P. Sanchez-Soria, T. D. Camenisch and R. R. Vaillancourt. Department of Pharmacology & Toxicology, The University of Arizona, Tucson, AZ. #2001 Poster Board Number.....................................534 INORGANIC ARSENITE IMPAIRS INSULIN- STIMULATED GLUCOSE UPTAKE IN 3T3-L1 ADIPOCYTES: INVOLVEMENT OF CELLULAR ADAPTIVE RESPONSE TO OXIDATIVE STRESS. P. Xue 1,2 , Y. Hou 1,2 , J. Fu 1 , C. G. Woods 1 , H. Liu 1 , Q. Zhang 1 , G. Sun 2 , M. E. Andersen 1 and J. Pi 1 . 1 The Hamner Institutes, Reaserach Triangle Park, NC and 2 China Medical University, Shenyang, China. #2002 Poster Board Number.....................................535 CHRONIC LOW-DOSE ARSENIC EXPOSURE ENHANCES HEPATIC INJURY INDUCED BY HIGH FAT DIET IN MICE. M. Tan 1,2 , R. H. Schmidt 1,2 , H. Zhong 1,2 , J. States 1 and G. E. Arteel 1,2 . 1 Pharmacology and Toxicology, University of Louisville, Louisville, KY and 2 Alcohol Research Center, University of Louisville, Louisville, KY. #2003 Poster Board Number.....................................536 ARSENIC-IRON INTERACTIONS IN FERRITIN: A NEW MODEL FOR ARSENIC TOXICITY. T. R. Radabaugh, T. J. Monks and S. S. Lau. Southwest Environmental Health Sciences Center, Department of Pharmacology/Toxicology, College of Pharmacy, The University of Arizona, Tucson, AZ. #2004 Poster Board Number.....................................537 REALGAR- AND CINNABAR- CONTAINING AN-GONG-NIU-HUANG WAN (AGNH) IS MUCH LESS ACUTELY TOXIC THAN SODIUM ARSENITE AND MERCURIC CHLORIDE. Y. Lu 2 , J. Yan 2 , Q. Wu 2 , J. Shi 3 , J. Liu 1,2 and J. Shi 2 . 1 Pharmacology, Toxicology & Therapeutics, University of Kansas Medical Center, Kansas City, KS, 2 Pharmacology, Zunyi Medical College, Zunyi, Guizhou, China and 3 Pharmacology, Guiyang Traditional Medicine College, Guiyang, Guizhou, China. #2005 Poster Board Number.....................................538 CINNABAR-CONTAINING ZHU-SHA- AN-SHENG WAN IS MUCH LESS CHRONICALLY NEPHROTOXIC THAN MERCURY CHLORIDE AND METHYLMERCURY IN RATS. J. Shi 2 , F. Kang 2 , Q. Wu 3 , Y. Lu 3 , J. Liu 1,3 and J. Y. Kang 4 . 1 Pharmacology, Toxicology & Therapeutics, University of Kansas Medical Center, Kansas City, KS, 2 Pharmacology, Guiyang Traditional Medical College, Guiyang, Guizhou, China, 3 Pharmacology, Zunyi Medical College, Zunyi, Guizhou, China and 4 Medicine, University of Louisville, Lousville, KY. #2006 Poster Board Number.....................................539 REALGAR AND REALGAR-CONTAINING LIU-SHEN-WAN ARE LESS ACUTELY TOXIC THAN ARSENITE AND ARSENATE. J. Liu 1,2 , S. Liang 2 , Y. Lu 2 , Q. Wu 2 , J. Miao 2 and J. Shi 2 . 1 Pharmacology, Toxicology & Therapeutics, University of Kansas Medical Center, Kansas City, KS and 2 Pharmacology, Zunyi Medical College, Zunyi, Guizhou, China. #2007 Poster Board Number.....................................540 AQUAGLYCEROPORIN 3 IS AN ARSENIC TRANSPORTER IN THE ATLANTIC KILLIFISH (FUNDULUS HETEROCLITUS): EFFECTS OF SALINITY. D. Jung 1 , B. Jackson 1 , B. MacIver 2 , C. Chapline 3 , D. Sato 3 , J. R. Shaw 3,4 and B. A. Stanton 1,3 . 1 Dartmouth Medical School, Hanover, NH, 2 Beth Israel Deaconess Medical Center and Havard Medical School, Boston, MA, 3 Mt. Desert Island Biological Laboratory, Salisbury Cove, ME and 4 Indiana University, Bloomington, IN. #2008 Poster Board Number.....................................541 LOW-LEVEL ARSENITE EXPOSURE THROUGH DRINKING WATER INCREASES BLOOD PRESSURE AND PROMOTES CONCENTRIC LEFT VENTRICULAR HYPERTROPHY IN MICE. P. Sanchez Soria 1 , D. Broka 1 and T. D. Camenisch 1,2,3 . 1 Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, AZ, 2 Steele Children’s Research Center, University of Arizona, Tucson, AZ and 3 Southwest Environmental Health Sciences Center, University of Arizona, Tucson, AZ. Sponsor: J. Gandolfi. #2009 Poster Board Number.....................................542 RELATIVE BIOAVAILABILITY OF ARSENIC CONTAMINATED SOILS IN A MOUSE MODEL. M. F. Hughes 1 , K. D. Bradham 2 , K. G. Scheckel 3 , P. Seales 1 , G. Lee 1 , C. Nelson 2 , A. Yeow 4 , S. Harper 2 and D. J. Thomas 1 . 1 ORD/NHEERL, U.S. EPA, Research Triangle Park, NC, 2 ORD/NERL, U.S. EPA, Research Triangle Park, NC, 3 ORD/ NRMRL, U.S. EPA, Cincinnati, OH and 4 SAB, U.S. EPA, Washington, D.C. 292 Education-Career Development Sessions Exhibitor Hosted Sessions Featured Sessions Historical Highlights Informational Sessions Platform Sessions
Society of Toxicology 2011 Program Description (Continued) Abstract # Wednesday Morning, March 9 9:00 AM to 12:30 PM Exhibit Hall Poster Session: Chemical and Biological Weapons Chairperson(s): Neera Tewari-Singh, University of Colorado Denver, Aurora, CO. Displayed: 9:00 AM–12:30 PM Author Attended: 11:00 AM–12:30 PM #2010 Poster Board Number.....................................601 EVALUATION OF A COMBINATION OF AN ISOFLAVONE AND AN ACE INHIBITOR FOR PREVENTION OF RADIATION- INDUCED INJURY. M. R. Landauer 1 , T. A. Davis 2 and R. M. Day 3 . 1 Armed Forces Radiobiology Research Institute, Bethesda, MD, 2 Department of Regenerative Medicine, Naval Medical Research Center, Silver Spring, MD and 3 Department of Pharmacology, Uniformed Services University of the Health Sciences, Bethesda, MD. #2011 Poster Board Number.....................................602 IDENTIFICATION OF A NOVEL VX METABOLITE FROM MINIPIG LIVER MICROSOMES VIA LC-Q-TOF MASS SPECTROMETRY. J. M. McGuire 1 , M. E. Parrish 2 , E. M. Jakubowski 1 and S. A. Thomson 1 . 1 U.S. Army Edgewood CB Center, Aberdeen Proving Ground, MD and 2 SAIC, Gunpowder, MD. #2012 Poster Board Number.....................................603 COMPARISON OF THE EFFECT UPON AND RECOVERY OF ACETYLCHOLINESTERASE (ACHE) ACTIVITY IN VARIOUS TISSUES AND BLOOD AFTER SUB-LETHAL INHALATION AND SUBCUTANEOUS CYCLOSARIN (GF) EXPOSURES. C. E. Whalley 1 , L. A. Lumley 2 , J. O’Donnell 2 , D. Miller 1 , W. Muse 1 and T. Shih 2 . 1 ECBC, Aberdeen Proving Ground, MD and 2 USAMRICD, Aberdeen Proving Ground, MD. #2013 Poster Board Number.....................................604 A DEEP DERMAL SKIN INJURY FOLLOWING EXPOSURE OF HAIRLESS GUINEA PIGS TO SULFUR MUSTARD VAPOR. S. Dachir, M. Cohen, L. Tverya, R. Sahar, H. Gutman, R. Gez, R. Brandeis, V. Horwitz and T. Kadar. Pharmacology, Israel Institute for Biological Research, Ness Ziona, Israel. Sponsor: J. Graham. #2014 Poster Board Number.....................................605 REACTIVATION OF ORGANOPHOSPHATE INHIBITED ACETYLCHOLINESTERASE (ACHE) BY NOVEL PYRIDINIUM OXIMES IN THE CENTRAL NERVOUS SYSTEM OF RATS. E. C. Meek 1 , H. W. Chambers 1 , J. Gearhart 2 , R. B. Pringle 1 and J. E. Chambers 1 . 1 Center for Environmental Health Sciences, Mississippi State University, Mississippi State, MS and 2 AFRL, Wright-Patterson AFB, OH. Abstract # #2015 Poster Board Number.....................................606 CATECHOLAMINE OVERLOAD AND CARDIAC LESION FORMATION IN RATS FOLLOWING EXPOSURE TO THE NERVE AGENT SOMAN. J. H. McDonough, K. E. Van Shura, M. E. Lyman, B. A. Capacio, J. C. O’Donnell and K. A. Whitten. U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD. #2016 Poster Board Number.....................................607 CENTRALLY ACTING THERAPEUTIC ADJUNCTS FOR NERVE AGENT INTOXICATION. I. Koplovitz, J. H. McDonough and T. Shih. Research Division, U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD. #2017 Poster Board Number.....................................608 RICIN TOXICITY IN BALB/C 3T3 CELLS: DOSE DEPENDENT PROTEIN EXPRESSION DETERMINED BY MASS SPECTROMETRY BASED PROTEOMICS. V. H. Bevilacqua 1 , S. Deshpande 2 , J. S. Madren-Whalley 3 , R. Jabbour 4 , K. Jones 5 , L. M. Reilly 6 and J. S. Rice 7 . 1 Point Detection Branch, Edgewood Chemical Biological Center, Aberdeen Proving Ground, MD, 2 STC, Edgewood, MD, 3 Biotechnology Branch, Edgewood Chemical Biological Center, Aberdeen Proving Ground, MD, 4 SAIC, Gunpowder, MD, 5 NuSep, Bogart, GA, 6 Physical Science Department, Bethany College, Bethany, WV and 7 Elona Biotechnologies, Inc., Greenwood, IN. Sponsor: J. Sekowski. #2018 Poster Board Number.....................................609 ASSESSMENT OF PRO-2-PRALIDOXIME (PRO-2-PAM) THERAPY FOR EXPOSURE TO ORGANOPHOSPHATE AGENTS IN GUINEA PIGS. J. C. DeMar 1 , S. M. Somerville 1 , R. H. Ratcliffe 1 , T. C. Ku 1 , N. M. Nur 1 , B. M. Ursic 1 , S. M. Schulz 2 , K. H. Smith 2 , E. D. Clarkson 2 and R. K. Gordon 1 . 1 Regulated Laboratories, Walter Reed Army Institute of Research, Silver Spring, MD and 2 Medical Toxicology Branch, U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD. #2019 Poster Board Number.....................................610 SULFUR MUSTARD-INDUCED RESPONSES OF AIRWAY AND SKIN IN VITRO. J. Seagrave, W. Weber and G. Grotendorst. Lovelace Respiratory Research Institute, Albuquerque, NM. #2020 Poster Board Number.....................................611 PREGABALIN REDUCES THE DURATION OF ACUTE SEIZURES INDUCED BY SOMAN EXPOSURE. M. Furtado 1 , F. Rossetti 1 , L. Lumley 2 , M. Addis 1 , M. Moffett 2 , B. Robertson 1 , K. Bailey 1 , S. Chanda 1 , N. Kelley 2 , M. Stone 2 , T. Pak 1 , S. Lichtenstein 1 and D. Yourick 1 . 1 Walter Reed Army Institute of Research, Silver Spring, MD and 2 U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Edgewood, MD. Wednesday Poster Sessions Regional Interest Session Roundtable Sessions Symposium Sessions Thematic Sessions Workshop Sessions 293
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50 th Anniversary Annual Meeting &
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Scientific Program Overview A page
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9:00 AM-12:30 PM POSTER SESSionS
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March 6-10, 2011 Walter E. Washingt
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Celebration Activities Historical H
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of the Society Regional Chapter Yea
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SOT Presidents 1961-2011 1966 1967
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The SOT Council Thanks and Recogniz
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of the Past 50 Years 2003 Michael D
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Toxicological Sciences The Official
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2011 SOT 50 th Anniversary Featured
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Society of Toxicology 2011 ToxExpo
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Creating a Safer and Healthier Worl
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SOT Job Bank YOUR RECRUITMENT AND E
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Society of Toxicology 2011 SOT 2011
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Society of Toxicology 2011 Author I
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Society of Toxicology 2011 2010-201
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Society of Toxicology 2011 Elected
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