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50 th Anniversary Annual Meeting and ToxExpo Program Description (Continued) Tuesday Abstract # Abstract # #1034 Poster Board Number.....................................313 EVALUATION OF A COMBINED DERMAL DEVELOPMENTAL AND PERINATAL/ POSTNATAL REPRODUCTION TOXICITY STUDY OF PEA (PHENETHYL ALCOHOL) IN RATS—INCLUDING AN EXAMINATION SKELETAL VARIANTS POSTNATALLY. V. T. Politano 1 , E. M. Lewis 2 , A. M. Hoberman 2 , R. M. Diener 3 and A. Api 1 . 1 Research Institute for Fragrance Materials, Inc., Woodcliff Lake, NJ, 2 Charles River Laboratories Preclinical Services, Horsham, PA and 3 Argus International, Inc., Horsham, PA. #1035 Poster Board Number.....................................314 PREGNENOLONE CO-TREATMENT DOES NOT RESTORE GROWTH OF MOUSE ANTRAL FOLLICLES TREATED IN VITRO WITH THE MONO-HYDROXYLATED METABOLITE OF METHOXYCHLOR. Z. R. Craig, P. R. Hannon and J. A. Flaws. Comparative Biosciences, University of Illinois, Urbana, IL. #1036 Poster Board Number.....................................315 DI-(2-ETHYLHEXYL) PHTHALATE AND MONO-(2-ETHYLHEXYL) PHTHALATE INHIBIT GROWTH OF OVARIAN ANTRAL FOLLICLES THROUGH AN OXIDATIVE STRESS PATHWAY. W. Wang, Z. R. Craig, M. S. Basavarajappa, R. K. Gupta and J. A. Flaws. Comparative Bioscience, University of Illinois, Urbana, Urbana, IL. #1037 Poster Board Number.....................................316 METHOXYCHLOR ALTERS STEROIDOGENIC ENZYMES IN CULTURED MOUSE ANTRAL FOLLICLES. M. Basavarajappa, Z. Craig, B. Karman, W. Wang and J. Flaws. Comparative Biosciences, University of Illinois, Urbana, IL. #1038 Poster Board Number.....................................317 ESTROGEN RECEPTOR ALPHA OVEREXPRESSING MOUSE OVARIES MAY BE SUSCEPTIBLE TO METHOXYCHLOR AND ITS METABOLITES BECAUSE OF REDUCED METABOLISM OF THE CHEMICALS. T. Paulose, I. Hernández-Ochoa, M. S. Basavarajappa, J. Peretz, Z. R. Craig and J. A. Flaws. Comparative Biosciences, University of Illinois Urbana-Champaign, Urbana, IL. #1039 Poster Board Number.....................................318 MONO- AND DI-ESTER PHTHALATES ALTER TESTOSTERONE PRODUCTION IN MOUSE BLTK1 MURINE LEYDIG TUMOR CELLS. Q. Ding 1 , N. A. Rahman 2 , I. T. Huhtaniemi 2 and T. R. Zacharewski 1 . 1 Department of Biochemistry & Molecular Biology and Center for Integrative Toxicology, Michigan State University, East Lansing, MI and 2 Department of Physiology, University of Turku, Turku, Finland. #1040 Poster Board Number.....................................319 A STUDY OF FERTILITY IN SPRAGUE- DAWLEY RATS WITH XOMA 052, A NOVEL MONOCLONAL ANTIBODY TARGETING IL-1 BETA. C. Gasper 1 , B. Thorsrud 2 , J. Ma 1 , L. Cao 1 , K. Der 1 and K. Meyer 1 . 1 Product Development, XOMA (U.S.) LLC, Berkeley, CA and 2 Developmental & Reproductive Toxicology, MPI Research, Mattawan, MI. #1041 Poster Board Number.....................................320 IMMUNOHISTOCHEMICAL AND CHIP MICROARRAY ANALYSIS OF PPARα IN FETAL RAT TESTES EXPOSED TO DIBUTYLPHTHALATE (DBP). S. M. Plummer 1 , D. Dan 1 , J. Quinney 1 , M. Millar 3 , M. Sheila 3 , N. Hallmark 2 , R. D. Phillips 2 and C. R. Elcombe 1 . 1 CXR Biosciences, Dundee, United Kingdom, 2 ExxonMobil Petroleum & Chemical, Hermeslaan, Belgium and 3 MRC Human Reproductive Sciences Unit, Edinburgh, United Kingdom. #1042 Poster Board Number.....................................321 GESTATIONAL EXPOSURE TO ATRAZINE HAS LITTLE EFFECT ON FEMALE REPRODUCTIVE PARAMETERS IN SPRAGUE-DAWLEY (SD) RATS. L. K. Davis, A. S. Murr, T. E. Stoker, M. Narotsky, J. M. Goldman and R. L. Cooper. Endocrine Toxicology Branch, NHEERL, U.S. EPA, Research Triangle Park, NC. #1043 Poster Board Number.....................................322 THE EFFECTS OF ENDOCRINE DISRUPTION ON THE DEVELOPING HUMAN FETAL PROSTATE. C. Saffarini, S. J. Hall and K. Boekelheide. Brown University, Providence, RI. #1044 Poster Board Number.....................................323 TWO-GENERATION REPRODUCTIVE TOXICITY STUDY OF ALUMINIUM SULFATE ADMINISTERED VIA DRINKING WATER TO RATS. M. Hirata-Koizumi 1 , S. Fujii 2 , A. Ono 1 , A. Hirose 1 , R. Hasegawa 1 , T. Imai 3 , K. Ogawa 1 , M. Ema 1 and A. Nishikawa 1 . 1 National Institute of Health Sciences, Tokyo, Japan, 2 Safety Research Institute for Chemical Compounds Co., Ltd., Sapporo, Japan and 3 Central Animal Laboratory, National Cancer Center Research Institute, Tokyo, Japan. #1045 Poster Board Number.....................................324 APPLICATION OF IN VIVO AND IN VITRO TOOLS FOR DETECTION OF EMBRYOTOXICITY: THE EXAMPLE OF ARTEMISININ-TYPE COMPOUNDS. P. Colombo, M. Longo, S. Zanoncelli and M. Brughera. Preclinical Development, Accelera Srl, Nerviano - Milano, Italy. #1046 Poster Board Number.....................................325 DEVELOPMENT OF REPRODUCTIVE ORGANS IN MALE CYNOMOLGUS MONKEYS. E. Haruyama 1,2 , Y. Ayukawa 1 , K. Kamura 1 , M. Mizutamari 1 , Y. Ooshima 1 , T. Sukamoto 1 , R. Nagata 1 and A. Tanimoto 2 . 1 Shin Nippon Biomedical Laboratories, Ltd., Kagoshima, Japan and 2 Kagoshima University, Kagoshima, Japan. #1047 Poster Board Number.....................................326 INTERACTIONS OF ENDOCRINE DISRUPTING CHEMICALS WITH THE BCRP TRANSPORTER: POTENTIAL MECHANISM FOR DICTATING FETAL EXPOSURE. L. Aleksunes and X. Wen. Pharmacology & Toxicology, Rutgers University, Piscataway, NJ. 208 Education-Career Development Sessions Exhibitor Hosted Sessions Featured Sessions Historical Highlights Informational Sessions Platform Sessions
Society of Toxicology 2011 Program Description (Continued) Abstract # #1048 Poster Board Number.....................................327 THE EFFECTS OF TRIS (2-ETHYLHEXYL) TRIMELLITATE (TOTM) ON GENE EXPRESSION ASSOCIATED WITH TESTICULAR MAL-DEVELOPMENT (TMD) IN RAT FETAL TESTES. C. R. Elcombe 1 , D. Dan 1 , D. G. Farrar 2 and S. M. Plummer 1 . 1 CXR Biosciences, Dundee, United Kingdom and 2 INEOS Chlor Limited, Runcorn, United Kingdom. Tuesday Morning, March 8 9:00 AM to 12:30 PM Exhibit Hall Poster Session: Reproductive Toxicology II Chairperson(s): Cathy Yang, CertiChem, Inc., Austin, TX. Displayed: 9:00 AM–12:30 PM Author Attended: 11:00 AM–12:30 PM #1049 Poster Board Number.....................................333 EPIVAGINAL TISSUE MODEL FOR PRECLINICAL SCREENING OF SINGLE OR REPEAT EXPOSURE TO VAGINALLY APPLIED CHEMICALS/FORMULATIONS. C. Cannon, M. Klausner, S. Ayehunie, A. Wang, K. LaRosa and T. Landry. MatTek Corp, Ashland, MA. Sponsor: P. J. #1050 Poster Board Number.....................................334 IVOS AND HISTOPATHOLOGY PROCEDURES FOR GLP-COMPLIANT TOXICOLOGY STUDIES IN NONHUMAN PRIMATES. R. E. Watson 1 , D. Thompson 1 , M. Novilla 1 , N. Makori 1 , R. Eyre 1 and R. Nagata 2 . 1 SNBL USA, Seattle, WA and 2 SNBL Laboratories, Kagoshima, Japan. #1051 Poster Board Number.....................................335 GOLD NANOPARTICLE EFFECTS ON RAT OVARIAN GENE EXPRESSION. J. Larson 1,3 , M. J. Carvan III 2,3 , R. Klaper 2,3 and R. J. Hutz 1,3 . 1 University of Wisconsin Milwaukee, Milwaukee, WI, 2 University of Wisconsin Milwaukee Great Lakes WATER Institute, Milwaukee, WI and 3 NIEHS Children’s Environmental Health Sciences Core Center at University of Wisconsin Milwaukee and Medical College of Wisconsin, Milwaukee, WI. #1052 Poster Board Number.....................................336 MONO-2-ETHYLHEXYL PHTHALATE INCREASES OXIDANT SPECIES PRODUCTION AND MODIFIES EXPRESSION OF REDOX-SENSITIVE GENES IN HUMAN PLACENTAL CELLS. L. M. Tetz and R. Loch-Caruso. Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI. #1053 Poster Board Number.....................................337 RELATIONSHIP BETWEEN LOW METABOLIC CAPABILITY OF LIGNANS AND IDIOPATHIC MALE INFERTILITY. Y. Xia, P. Zhu, M. Chen, C. Lu, S. Wang and X. Wang. Institute of Toxicology, Nanjing Medical University, Nanjing, China. Abstract # #1054 Poster Board Number.....................................338 INHIBITION OF OVARIAN KIT AUTOPHOSPHORLATION BY THE OVOTOXICANT 4-VINYLCYCLOHEXENE DIEPOXIDE. C. J. Kappeler 1 , L. McKee 1 , I. Sipes 2 , J. Konhilas 1 and P. B. Hoyer 1 . 1 Physiology, University of Arizona, Tucson, AZ and 2 Pharmacology, University of Arizona, Tucson, AZ. #1055 Poster Board Number.....................................339 A DOSE-RESPONSE STUDY FOLLOWING LATE GESTATIONAL EXPOSURE TO THE PHTHALATE METABOLITE, MONO-2-ETHYLHEXYL PHTHALATE (MEHP): EFFECTS ON FEMALE MOUSE REPRODUCTIVE DEVELOPMENT. B. J. Moyer and M. L. Hixon. Brown University, Providence, RI. #1056 Poster Board Number.....................................340 TETRABROMOBISPHENOL A STIMULATES SECRETION OF INTERLEUKIN 6 FROM HUMAN FIRST TRIMESTER TROPHOBLASTS. P. W. Kimani and R. Loch- Caruso. Environmental Health Sciences, University of Michigan, Ann Arbor, MI. #1057 Poster Board Number.....................................341 OXIDANT-INDUCED INFLAMMATORY RESPONSE IN HUMAN PLACENTAL CELLS IS DEPENDENT ON MITOGEN ACTIVATED PROTEIN KINASES (MAPKS). C. S. Korte and R. Loch-Caruso. Environmental Health Science, University of Michigan, Ann Arbor, MI. #1058 Poster Board Number.....................................342 REGULATION OF HUMAN PLACENTAL DRUG TRANSPORTERS IN RESPONSE TO BACTERIAL CELL WALL COMPONENTS. L. Yacovino 1 , A. Vetrano 2 , N. Hanna 3 and L. M. Aleksunes 1 . 1 Pharmacology & Toxicology, Rutgers University, Piscataway, NJ, 2 Pediatrics, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ and 3 Pediatrics, Winthrop University Hospital, Mineola, NY. #1059 Poster Board Number.....................................343 ALCOHOL DRINKING-PROMOTED ACETALDEHYDE ACCUMULATION AND OXIDATIVE STRESS IN RAT TESTES. G. D. Castro, L. N. Quintans, F. M. Bietto, M. I. Díaz Gómez and J. A. Castro. CEITOX, CONICET- UNSAM, San Martín, Buenos Aires, Argentina. #1060 Poster Board Number.....................................344 NONHUMAN PRIMATE POSTNATAL DEVELOPMENT: HISTORICAL CONTROL DATA IN NONCLINICAL TOXICOLOGY STUDIES. N. Lalayeva 1 , J. Kenfield 1 , J. Cowan 2 , S. Oneda 1 , N. Makori 1 , R. Eyre 1 , H. Tsusaki 1 and R. Nagata 3 . 1 SNBL USA, Ltd., Everett, WA, 2 Consultant for NHP Infant Behavior, San Francisco, CA and 3 Shin Nippon Biomedical Laboratories, Ltd., Kagoshima, Japan. #1061 Poster Board Number.....................................345 MENSTRUAL CYCLE AND SERUM HORMONE DATA IN MATURE CYNOMOLGUS MONKEYS. S. Oneda 1 , N. Lalayeva 1 , R. Watoson 1 , N. Makori 1 , R. Eyre 1 , H. Tsusaki 1 and R. Nagata 2 . 1 SNBL USA, Ltd., Everett, WA and 2 Shin Nippon Biomedical Laboratories, Ltd., Tokyo, Japan. Tuesday Poster Sessions Regional Interest Session Roundtable Sessions Symposium Sessions Thematic Sessions Workshop Sessions 209
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50 th Anniversary Annual Meeting &
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Scientific Program Overview A page
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9:00 AM-12:30 PM POSTER SESSionS
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March 6-10, 2011 Walter E. Washingt
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Celebration Activities Historical H
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of the Society Regional Chapter Yea
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SOT Presidents 1961-2011 1966 1967
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The SOT Council Thanks and Recogniz
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of the Past 50 Years 2003 Michael D
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50 th Anniversary Annual Meeting an
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Toxicological Sciences The Official
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Society of Toxicology 2011 Walter E
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2011 SOT 50 th Anniversary Featured
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Society of Toxicology 2011 ToxExpo
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Creating a Safer and Healthier Worl
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Society of Toxicology 2011 General
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SOT Job Bank YOUR RECRUITMENT AND E
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Society of Toxicology 2011 SOT 2011
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Society of Toxicology 2011 Recognit
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Society of Toxicology 2011 Recognit
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Society of Toxicology 2011 Outreach
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Society of Toxicology 2011 Program
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Society of Toxicology 2011 Author I
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Society of Toxicology 2011 Abstract
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Society of Toxicology 2011 2010-201
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Society of Toxicology 2011 Elected
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Society of Toxicology 2011 Elected
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Society of Toxicology 2011 SOT Affi
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