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50 th Anniversary Annual Meeting and ToxExpo Program Description (Continued) Wednesday Abstract # Abstract # #2071 Poster Board Number.....................................721 AN IN VITRO INVESTIGATION OF THE TOXICITY OF SILVER NANOPARTICLES. P. Sriwichai, F. M. Williams, C. Lye, A. Silmon, A. Groom and E. Mutch. Medical Faculty, Institute of Cellular Medicine, Newcastle Upon Tyne, Tyne and Wear, United Kingdom. Sponsor: M. Graham. #2072 Poster Board Number.....................................722 IRON OXIDE NANOPARTICLES CAUSE OXIDATIVE STRESS AND DERMAL TOXICITY. A. R. Murray 1,2 , E. Kisin 1 , A. O. Inman 3 , S. H. Young 1 , M. Muhammed 4 , T. Burks 4 , A. Uheida 4 , A. Tkach 1 , M. Waltz 2 , V. Castranova 1 , B. Fadeel 5 , J. E. Riviere 3 , V. E. Kagan 6 , N. A. Monteiro- Riviere 3 and A. A. Shvedova 1,2 . 1 PPRB, NIOSH, Morgantown, WV, 2 West Virginia University, Morgantown, WV, 3 North Carolina State University, Raleigh, NC, 4 Royal Institute of Technology, Stockholm, Sweden, 5 Karolinska Institute, Stockholm, Sweden and 6 University of Pittsburgh, Pittsburgh, PA. #2073 Poster Board Number.....................................723 A TOXICOGENOMIC ANALYSIS OF GENE EXPRESSION CHANGES IN TIO2 NANOPARTICLE-TREATED MICE. S. Liu, Y. Yao, W. Yang, X. Ding and J. Gu. Wadsworth Center, New York State Department of Health, and School of Public Health, State University of New York at Albany, Albany, NY. #2074 Poster Board Number.....................................724 GOLD NANOPARTICLES INCREASE THE LIVER TOXICITY OF ACETAMINOPHEN. A. M. Keene, A. Knapton, N. R. Hartman, D. Peters, G. Tobin, L. Zhang, S. Stewart, L. Xu, R. Rouse and K. M. Tyner. Center for Drug Evaluation and Research, U.S. FDA, Laurel, MD. #2075 Poster Board Number.....................................725 SILVER NANOPARTICLES-INDUCED GENOTOXICITY IN BONE MARROW CELLS OF SPRAGUE-DAWLEY RATS. A. Patlolla 1 and D. Hackett 1,2 . 1 Molecular Toxicology Research Laboratory, Jackson State University, Jackson, MS and 2 Biology, Jackson State University, Jackson, MS. #2076 Poster Board Number.....................................726 TOXICOLOGICAL ACTIVITY OF METAL OXIDE NANOPARTICLES UPON BIOLOGICAL MODELS IN VITRO. T. D. Palacios-Hernandez 1,2 , J. L. Garate-Morales 1 , F. Cordova-Lozano 2 , J. L. Sanchez-Salas 2 , C. C. Berry 3 , E. Gonzalez-Vergara 1 and M. A. Mendez-Rojas 2 . 1 Centre of Chemstry and Faculty of Chemical Sciences, Benemerita Universidad Autonoma de Puebla, Puebla, Mexico, 2 Chemical and Biological Sciences, Universidad de las Americas, Puebla, San Andres Cholula, Puebla, Mexico and 3 Centre for Cell Engineering, University of Glasgow, Glasgow, United Kingdom. Sponsor: O. Olivero. #2077 Poster Board Number.....................................727 EVALUATION OF GENOTOXICITY OF TITANIUM DIOXIDE NANOPARTICLES USING THE AMES TEST AND IN VITRO COMET ASSAY. J. Yan 1 , R. S. Woodruff 2 , M. Y. Jones 3 , F. Watanabe 4 , A. Biris 4 and T. Chen 1 . 1 Division of Genetic and Molecular Toxicology, U.S. FDA NCTR, Jefferson, AR, 2 Division of Microbiology, Arkansas Regional Laboratory, U.S. FDA, Jefferson, AR, 3 Nanotechnology Facility, U.S. FDA NCTR, Jefferson, AR and 4 Nanotechnology Center, University of Arkansas at Little Rock, Little Rock, AR. #2078 Poster Board Number.....................................728 A COMPARISON OF THE PHOTOTOXIC POTENCY OF SIX TYPES OF TIO2 NANOPARTICLES. W. K. Boyes 1 , K. M. Sanders 1 , L. L. Degn 1 , R. M. Zucker 1 , W. R. Mundy 2 , B. Zhao 3 and J. E. Roberts 4,3 . 1 Toxicity Assessment Division, U.S. EPA, Research Triangle Park, NC, 2 Integrated Systems Toxicology Division, U.S. EPA, Research Triangle Park, NC, 3 National Institute of Environmental Health Sciences, Research Triangle Park, NC and 4 Fordham University, New York, NY. #2079 Poster Board Number.....................................729 INHIBITORY EFFECTS OF SILVER NANOPARTICLES ON RECOMBINANT CYTOCHROME P450 ENZYMES AND HUMAN LIVER MICROSOMES. R. Maniratanachote 1 , K. Kulthong 1 , Y. Kobayashi 2 , T. Fukami 2 and T. Yokoi 2 . 1 National Nanotechnology Center, National Science and Technology Development Agency, Klong Luang, Pathumthani, Thailand and 2 Faculty of Pharmaceutical Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Japan. #2080 Poster Board Number.....................................730 EFFECT OF ORALLY EXPOSURED AMORPHOUS NANOSILICA ON ANTIGEN- SPECIFIC IMMUNE RESPONSES. T. Yoshida 1,2 , T. Yoshikawa 1,2 , S. Tochigi 1,2 , T. Hirai 1,2 , M. Uji 1,2 , H. Nabeshi 1,2 , K. Nagano 2 , Y. Abe 2 , H. Kamada 2,3 , S. Tsunoda 2,3,4 , N. Itoh 1,2 , Y. Yoshioka 1,2,3 and Y. Tsutsumi 1,2,3 . 1 Department of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan, 2 Laboratory of Biopharmaceutical Research, National Institute of Biomedical Innovation, Osaka, Japan, 3 The Center for Advanced Medical Engineering and Informatics, Osaka University, Osaka, Japan and 4 Department of Biomedical Innovation, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan. #2081 Poster Board Number.....................................731 MATRIX METALLOPROTEINASES 2 AND 9 AND TISSUE INHIBITORS OF METALLOPROTEINASE 1 IN CERIUM OXIDE INDUCED PULMONARY FIBROSIS. J. Y. Ma 1 , R. R. Mercer 1 , M. Barger 1 , J. K. Ma 2 and V. Castranova 1 . 1 PPRB/HELD, NIOSH, Morgantown, WV and 2 School of Pharmacy, West Virginia University, Morgantown, WV. 298 Education-Career Development Sessions Exhibitor Hosted Sessions Featured Sessions Historical Highlights Informational Sessions Platform Sessions
Society of Toxicology 2011 Program Description (Continued) Abstract # #2082 Poster Board Number.....................................732 PULMONARY TOXICITY OF CRYSTALLINE SILICA AFTER A SINGLE INTRATRACHEAL INSTILLATION IN RATS. M. Naya 1 , N. Kobayashi 1 , S. Endoh 2 , K. Mizuno 3 , R. Nagaosa 1 , M. Ema 1 and J. Nakanishi 1 . 1 Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan, 2 Research Institute for Environmental Management Technology, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan and 3 Metrology Institute of Japan, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan. #2083 Poster Board Number.....................................733 SIZE-DEPENDENT IMMUNE-MODULATING EFFECT OF AMORPHOUS NANOSILICA. T. Hirai 1,2 , T. Yoshikawa 1,2 , T. Yoshida 1,2 , H. Nabeshi 1,2 , S. Tochigi 1,2 , M. Uji 1,2 , K. Nagano 2 , Y. Abe 2 , H. Kamada 2,3 , S. Tsunoda 2,3,4 , N. Itoh 1,2 , Y. Yoshioka 1,2,3 and Y. Tsutsumi 1,2,3 . 1 Department of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan, 2 Laboratory of Biopharmaceutical Research, National Institute of Biomedical Innovation, Osaka, Japan, 3 The Center for Advanced Medical Engineering and Informatics, Osaka University, Osaka, Japan and 4 Department of Biomedical Innovation, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan. #2084 Poster Board Number.....................................734 DISTRIBUTION IN THE TESTIS AND REPRODUCTIVE EFFECTS OF NANOSILICA. Y. Morishita 1,2 , Y. Yoshioka 1,2,3 , K. Yamashita 1,2 , K. Higashisaka 1,2 , M. Fujimura 1,2 , H. Pan 1,2 , T. Ogura 1,2 , K. Nagano 2 , Y. Abe 2 , H. Kamada 2,3 , S. Tsunoda 2,3,4 , H. Nabeshi 1 , N. Itoh 1 , T. Yoshikawa 1,2 and Y. Tsutsumi 1,2,3 . 1 Department of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan, 2 Laboratory of Biopharmaceutical Research, National Institute of Biomedical Innovation, Ibaraki, Osaka, Japan, 3 The Center for Advanced Medical Engineering and Informatics, Osaka University, Suita, Osaka, Japan and 4 Department of Biomedical Innovation, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan. #2085 Poster Board Number.....................................735 BIODISTRIBUTION AND REPRODUCTIVE TOXICITY OF NANOSILICA FOR ENSURING THE SAFETY OF NANOMATERIALS. K. Yamashita 1,2 , Y. Yoshioka 1,2,3 , K. Higashisaka 1,2 , M. Fujimura 1,2 , Y. Morishita 1,2 , H. Pan 1,2 , T. Ogura 1,2 , H. Nabeshi 1 , K. Nagano 2 , Y. Abe 2 , H. Kamada 2,3 , S. Tsunoda 2,3,4 , N. Itoh 1,2 , T. Yoshikawa 1,2 and Y. Tsutsumi 1,2,3 . 1 Department of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan, 2 Laboratory of Biopharmaceutical Research, National Institute of Biomedical Innovation, Osaka, Japan, 3 The Center for Advanced Medical Engineering and Informatics, Osaka University, Osaka, Japan and 4 Department of Biomedical Innovation, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan. Abstract # Wednesday Morning, March 9 9:00 AM to 12:30 PM Exhibit Hall Poster Session: Pesticides: General Chairperson(s): Diane Hardej, St. Johns University, Jamaica, NY, and Virginia Moser, U.S. EPA, Research Triangle Park, NC. Displayed: 9:00 AM–12:30 PM Author Attended: 11:00 AM–12:30 PM #2086 Poster Board Number.....................................801 INACTIVATION OF ENDOCANNABINOID METABOLISM IN HUMAN THP1 MACROPHAGES FOLLOWING EXPOSURE TO ACTIVATED ORGANOPHOSPHOTHIONATES. M. K. Ross 1 , A. Borazjani 1 and P. M. Potter 2 . 1 Mississippi State University, Mississippi State, MS and 2 St. Jude Children’s Hospital, Memphis, TN. #2087 Poster Board Number.....................................802 ETHYLENE BISDITHOCARBAMATE PESTICIDES MANEB AND MANCOZEB CAUSE TOXICITY IN NORMAL AND TRANSFORMED COLON CELLS. H. M. Lisa and D. Hardej. Department of Pharmaceutical Sciences, St. John’s University, Queens, NY. #2088 Poster Board Number.....................................803 RETINOIC ACID AND TESTOSTERONE LEVELS IN TESTIS AFTER MOLINATE: IN VITRO AND IN VITRO STUDIES. F. G. Zuno, B. S. Winder, D. Holstege and M. G. Miller. Environmental Toxicology, University of California, Davis, CA. #2089 Poster Board Number.....................................804 CHARACTERIZATION OF CHLORPYRIFOS TOXICITY ON THE PANCREATIC BETA CELL LINE RINM5F. Z. Yan and D. R. Cool. Pharmacology/Toxicology, Wright State University, Dayton, OH. Sponsor: C. Sulentic. #2090 Poster Board Number.....................................805 EARLY DEVELOPMENTAL EXPOSURE TO THE HERBICIDE ATRAZINE RESULTS IN ENRICHMENT OF GENE EXPRESSION ALTERATIONS ASSOCIATED WITH NEUROENDOCRINE DEVELOPMENT AND CARCINOGENESIS. G. J. Weber 1 , S. S. Lewis 2 , S. M. Peterson 1 , M. S. Sepúlveda 2 and J. L. Freeman 1 . 1 Health Sciences, Purdue University, West Lafayette, IN and 2 Forestry and Natural Resources, Purdue University, West Lafayette, IN. #2091 Poster Board Number.....................................806 CHANGES IN EXPRESSION OF CRITICAL PROSTATE CANCER GENES UPON EXPOSURE TO ENVIRONMENTAL ANTI- ANDROGENIC PESTICIDE VINCLOZOLIN. S. Prasad 1 , M. Sienkiewicz 1 , B. Nguyen 1 , S. Ramoju 1 , P. O’Reilly 1 and J. Gomes 2,3 . 1 Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada, 2 Health Science Program, University of Ottawa, Ottawa, ON, Canada and 3 Institute of Population Health, University of Ottawa, Ottawa, ON, Canada. Wednesday Poster Sessions Regional Interest Session Roundtable Sessions Symposium Sessions Thematic Sessions Workshop Sessions 299
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50 th Anniversary Annual Meeting &
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Scientific Program Overview A page
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9:00 AM-12:30 PM POSTER SESSionS
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March 6-10, 2011 Walter E. Washingt
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Celebration Activities Historical H
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SOT Presidents 1961-2011 1966 1967
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Society of Toxicology 2011 2010-201
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