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50 th Anniversary Annual Meeting and ToxExpo Program Description (Continued) MONday Abstract # Abstract # #339 Poster Board Number.....................................637 EFFICIENT SCORING OF MICRONUCLEI AND CELL CYCLE STATUS IN THE RECONSTRUCTED SKIN MICRONUCLEUS (RSMN) ASSAY USING FLOW CYTOMETRY. M. Crosby 1 , E. Dahl 2 , S. Bryce 3 , A. Allemang 1 , S. Brown 1 and S. Pfuhler 1 . 1 Procter & Gamble Company, Cincinnati, OH, 2 Institute for In Vitro Sciences, Gaithersburg, MD and 3 Litron Laboratories, Rochester, NY. #340 Poster Board Number.....................................638 NEXT GENERATION DEL ASSAY: RAPID AND ACCURATE ASSESSMENT OF TOXICITY. Y. Rivina and R. H. Schiestl. Environmental Health Sciences, University of California, Los Angeles, Los Angeles, CA. #341 Poster Board Number.....................................639 THE RECONSTRUCTED SKIN COMET ASSAY SHOWS GOOD INTRA- AND INTER- LABORATORY REPRODUCIBILITY: RESULTS FROM THREE LABORATORIES. T. Downs 1 , A. Reus 2 , K. Reisinger 3 , C. Krul 2 and S. Pfuhler 1 . 1 Procter & Gamble Company, Cincinnati, OH, 2 TNO Quality of Life, Zeist, Netherlands and 3 Henkel AG & Co KgaA, Düsseldorf, Germany. Sponsor: G. Daston. #342 Poster Board Number.....................................640 CHLORPYRIFOS DOES NOT INDUCE RAT BRAIN DNA DAMAGE OR BONE MARROW MICRONUCLEUS FORMATION IN A MICRONUCLEUS AND COMET COMBINATION ASSAY. Y. Xu, K. Carl and L. Timothy. Covance, Vienna, VA. #343 Poster Board Number.....................................641 GENOTOXICITY TESTING USING THE MICRONUCLEUS AND COMET ASSAYS IN NORMAL HUMAN CELL BASED 3D EPITHELIAL MODELS. J. DeLuca, Y. Kaluzhny, P. J. Hayden, A. Armento, V. Karetsky and M. Klausner. MatTek Corp, Ashland, MA. Monday Morning, March 7 9:30 AM to 12:30 PM Exhibit Hall Poster Session: Receptor and Receptor-Mediated Toxicity Chairperson(s): Angela Slitt, University of Rhode Island, Kingston, RI. Displayed: 9:30 AM–12:30 PM Author Attended: 11:00 AM–12:30 PM #344 Poster Board Number.....................................701 COLOCALIZATION OF CANNABINOID RECEPTOR SUBTYPES IN CULTURED RAT CORTICAL ASTROGLIAL CELLS. J. A. Torres 1,2 and A. Shivachar 2 . 1 Environmental Toxicology, Texas Southern University, Houston, TX and 2 College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX. #345 Poster Board Number.....................................702 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR γ IS ACTIVATED BY 15-DEOXY-PGJ 2 -G, A PUTATIVE METABOLITE OF THE ENDOCANNABINOID, 2-ARACHIDONYL GLYCEROL. P. Raman 1,2 , B. Kaplan 1,2 , J. Thompson 3 , J. Vanden Heuvel 3 and N. Kaminski 1,2 . 1 Pharmacology & Toxicology, Michigan State University, East Lansing, MI, 2 Center for Integrative Toxicology, Michigan State University, East Lansing, MI and 3 Veterinary Science & Biomedical Sciences, Center for Molecular Toxicology and Carcinogenesis, Pennsylvania State University, University Park, PA. #346 Poster Board Number.....................................703 PHARMACOLOGICAL STUDY OF SEROTONIN AND DOPAMINE POST- SYNAPTIC RECEPTORS OF THE LATERAL CILIATED CELLS OF THE GILL AND VISCERAL GANGLIA OF CRASSOSTREA VIRGINICA. C. Brown, Z. Bandaogo, E. J. Catapane, M. A. Carroll, A. Hernandez and D. Adebesin. Biology, Medgar Evers College, Brooklyn, NY. #347 Poster Board Number.....................................704 SPECIFIC AMINO ACID RESIDUES WITHIN THE LIGAND BINDING DOMAIN CONFER LOW RESPONSIVENESS TO 2, 3, 7, 8-TETRACHLORODIBENZO-P-DIOXIN (TCDD) TO AN ARYL HYDROCARBON RECEPTOR (AHR) FROM THE FROG XENOPUS LAEVIS. C. Odio 1 , S. A. Holzman 1 , M. S. Denison 2 , L. Bonati 3 and W. H. Powell 1 . 1 Biology, Kenyon College, Gambier, OH, 2 Environmental Toxicology, University of California Davis, Davis, CA and 3 Scienze dell’Ambiente e del Territorio, Universita` degli Studi di Milano-Bicocca, Milano, Italy. #348 Poster Board Number.....................................705 THE NOVEL DAPHNIA NUCLEAR RECEPTOR, HR97G, IS ACTIVATED BY JUVENILE HORMONE ANALOGS. G. Ginjupalli 2 , Y. Li 2 and W. S. Baldwin 2,1 . 1 Biological Sciences, Clemson University, Clemson, SC and 2 Environmental Toxicology Program, Clemson University, Clemson, SC. #349 Poster Board Number.....................................706 LIGAND-ACTIVATED AHR ALTERS THE EXPRESSION OF GENES IN THE HUMAN EPIDERMAL DIFFERENTIATION COMPLEX. C. H. Sutter, S. Bodreddigari, C. Campion, R. Wible and T. Sutter. Biological Sciences, University of Memphis, Memphis, TN. #350 Poster Board Number.....................................707 ACTIVATING PKCβ1 AT THE BLOOD- BRAIN BARRIER (BBB) REVERSES INDUCTION OF P-GLYCOPROTEIN (PGP) ACTIVITY BY DIOXIN AND RESTORES DRUG DELIVERY TO THE CNS. X. Wang, B. Hawkins and D. Miller. Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, NC. 144 Education-Career Development Sessions Exhibitor Hosted Sessions Featured Sessions Historical Highlights Informational Sessions Platform Sessions
Society of Toxicology 2011 Program Description (Continued) Abstract # #351 Poster Board Number.....................................708 ARYL HYDROCARBON RECEPTOR ANTAGONISTS INHIBIT ADIPOCYTE- BREAST CANCER CELL INTERACTIONS. T. Salisbury, R. Jones, M. Hodge, K. Geronilla and N. Santanam. Marshall University School of Medicine, Huntington, WV. Sponsor: M. Valentovic. #352 Poster Board Number.....................................709 DUAL PPAR/RXR AGONIST TRIBUTYLTIN UNIQUELY IMPACTS BONE INTEGRITY AND MARROW MICROENVIRONMENT. A. H. Baker 1 , B. D. Meeks 2 , K. K. Mann 3 , L. C. Gerstenfeld 2 and J. J. Schlezinger 4 . 1 Medicine, Boston University, Boston, MA, 2 Orthopedic Surgery, Boston University, Boston, MA, 3 Oncology, McGill University, Montréal, QC, Canada and 4 Environmental Health, Boston University, Boston, MA. #353 Poster Board Number.....................................710 MOLECULAR AND FUNCTIONAL CHARACTERIZATION OF ARYL HYDROCARBON RECEPTOR REPRESSOR (AHRR) FROM THE CHICKEN (GALLUS GALLUS). H. Iwata 1 , J. Lee 1 , E. Kim 2 and K. Nomaru 1 . 1 Center for Marine Environmental Studies, Ehime University, Matsuyama, Japan and 2 Department of Life and Nanopharmaceutical Science and Department of Biology, Kyung Hee University, Seoul, Republic of Korea. #354 Poster Board Number.....................................711 STABLE OVER-EXPRESSION OF PPAR/ AND PPAR TO EXAMINE RECEPTOR SIGNALING IN HUMAN HaCaT KERATINOCYTES. P. S. Palkar 1 , M. G. Borland 1 , C. Khozoie 1 , B. Zhu 1 , C. Lee 1 , F. J. Gonzalez 2 and J. M. Peters 1 . 1 Veterinary Sciences, Pennsylvania State University, State College, PA and 2 Laboratory of Metabolism, National Cancer Institute, Bethesda, MD. #355 Poster Board Number.....................................712 PPAR/MODULATES AHR SIGNALING IN MOUSE AND HUMAN KERATINOCYTES. J. Morales 1 , M. G. Borland 1 , C. Lee 1 , F. J. Gonzalez 2 and J. M. Peters 1 . 1 Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA and 2 Laboratory of Metabolism, National Cancer Institute, Bethesda, MD. #356 Poster Board Number.....................................713 ROLE OF 2, 3, 7, 8-TETRACHLORODIBENZO-P-DIOXIN- INDUCIBLE POLY(ADP-RIBOSE) POLYMERASE IN DIOXIN-INDUCED ARYL HYDROCARBON RECEPTOR SIGNALING. L. M. MacPherson and J. Matthews. Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada. #357 Poster Board Number.....................................714 PPARβ/δ INHIBITS VIRAL HRAS1 (V-HRAS1)-INDUCED NEOPLASTIC/ MALIGNANT TRANSFORMATION OF MOUSE PRIMARY KERATINOCYTES. B. Zhu 1 , C. Khozoie 1 , M. T. Bility 1 , N. Blazanin 1 , A. B. Glick 1 , F. J. Gonzalez 2 and J. M. Peters 1 . 1 Molecular Toxicology, University Park, PA and 2 Laboratory of Metabolism, National Cancer Institute, Bethesda, MD. Abstract # #358 Poster Board Number.....................................715 CHARACTERIZATION OF GENOME-WIDE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-/ (PPAR/) BINDING AND TRANSCRIPTIONAL REGULATION. C. Khozoie 1 , M. G. Borland 1 , B. Zhu 1 , F. J. Gonzalez 2 and J. M. Peters 1 . 1 Department of Veterinary and Biomedical Sciences and The Center for Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, PA and 2 Laboratory of Metabolism, National Cancer Institute, Bethesda, MD. #359 Poster Board Number.....................................716 FUNCTIONAL CHARACTERIZATION OF PEROXISOME PROLIFERATOR- ACTIVATED RECEPTOR-/(PPAR/) EXPRESSION IN COLON CANCER. J. E. Foreman 1 , W. Chang 2 , J. L. Williams 3 , M. L. Clapper 2 , F. J. Gonzalez 4 and J. M. Peters 1 . 1 Department of Veterinary and Biomedical Sciences and The Center for Molecular Toxicology and Carcinogenesis, Pennsylvania State University, University Park, PA, 2 Cancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, PA, 3 Cancer Prevention Laboratory, State University of New York at Stony Brook, Stony Brook, NY and 4 Laboratory of Metabolism, National Cancer Institute, Bethesda, MD. #360 Poster Board Number.....................................717 REDEFINING ARYL HYDROCARBON RECEPTOR ANTAGONISM THROUGH CHARACTERIZATION OF A NEW LIGAND. K. J. Smith 1 , I. A. Murray 1 , R. Tanos 1 , Y. Wang 2 , J. E. Tellew 2 , A. E. Boitano 2 , M. P. Cooke 2 and G. H. Perdew 1 . 1 Pennsylvania State University, University Park, PA and 2 Genomics Institute of the Novartis Foundation, San Diego, CA. #361 Poster Board Number.....................................718 COMPARISON OF EFFECTS OF DIFFERENT LIGANDS AND Y322 ON ARYL HYDROCARBON RECEPTOR SIGNALING. M. L. Powis, T. Celius and J. Matthews. Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada. #362 Poster Board Number.....................................719 IMMUNOMODULATORY EFFECT OF ARYL HYDROCARBON RECEPTOR ANTAGONISM ALTERS INFLAMMATORY PHENOTYPE IN HFLS-RA CELLS. T. S. Lahoti, I. A. Murray and G. H. Perdew. Veterinary Sciences, The Pennsylvania State University, University Park, PA. #363 Poster Board Number.....................................720 AH RECEPTOR ANTAGONIST TREATMENT CAN ALTER THE AGGRESSIVE PHENOTYPE OF HEAD AND NECK SQUAMOUS CELL CARCINOMA CELL LINES. B. DiNatale and G. H. Perdew. Pennsylvania State University, University Park, PA. MONday Poster Sessions Regional Interest Session Roundtable Sessions Symposium Sessions Thematic Sessions Workshop Sessions 145
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50 th Anniversary Annual Meeting &
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Scientific Program Overview A page
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9:00 AM-12:30 PM POSTER SESSionS
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March 6-10, 2011 Walter E. Washingt
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Celebration Activities Historical H
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SOT Presidents 1961-2011 1966 1967
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Toxicological Sciences The Official
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SOT Job Bank YOUR RECRUITMENT AND E
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Society of Toxicology 2011 2010-201
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