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50 th Anniversary Annual Meeting and ToxExpo Program Description (Continued) Wednesday Abstract # Abstract # #2329 Poster Board Number.....................................528 AIRBORNE ORGANIC PARTICULATE MATTER AS A LUNG INFLAMMATION INDUCER: ROLE OF PHOSPHOLIPASE A2. S. R. Kotha 1 , M. G. Piper 1 , B. P. Caristophe 1 , N. Patric 1 , R. M. Uppu 2 , M. B. Clay 1 and N. L. Parinandi 1 . 1 Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, The Ohio State University College of Medicine, Columbus, OH and 2 Department of Environmental Toxicology, Southern University and A&M College, Baton Rouge, LA. #2330 Poster Board Number.....................................529 THE ROLE OF TRANSFORMING GROWTH FACTOR BETA 1 (TGF-β1) IN TOBACCO- SMOKE-INDUCED LUNG INJURIES. L. L. Hoang and K. E. Pinkerton. Center for Health and the Environment, University of California Davis, Davis, CA. #2331 Poster Board Number.....................................530 RESPIRATORY AND SYSTEMIC RESPONSES TO URBAN SUMMER AND WINTER SUB-MICRON FINE AND ULTRAFINE PARTICULATE MATTER. L. E. Plummer 1 , C. M. Carosino 1 , K. J. Bein 2 , A. S. Wexler 2 and K. E. Pinkerton 1 . 1 Center for Health and the Environment, University of California, Davis, CA and 2 Civil and Environmental Engineering, University of California, Davis, CA. #2332 Poster Board Number.....................................531 PARTICLE UPTAKE OF GASEOUS AIR TOXICS MODIFIES OBSERVED TOXICITY OF PM. S. M. Ebersviller 1 , K. Lichtveld 1 , J. Zavala 1 , Y. Lin 1 , K. G. Sexton 1 , I. Jaspers 1,2 and H. Jeffries 1 . 1 Environment Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC and 2 CEMALB, University of North Carolina at Chapel Hill, Chapel Hill, NC. #2333 Poster Board Number.....................................532 CONTRIBUTIONS OF TRPV1 AND TRPM8 TO LUNG INJURY BY COAL FLY ASH. C. A. Reilly, C. E. Deering-Rice, M. E. Johansen, J. K. Roberts, E. G. Romero, J. M. Veranth and G. S. Yost. Pharmacology and Toxicology, University of Utah, Salt Lake City, UT. #2334 Poster Board Number.....................................533 ACTIVATION OF HUMAN TRPA1 BY DIESEL EXHAUST PARTICLES (DEP): ASSOCIATION WITH LUNG INJURY. C. Deering-Rice, E. G. Romero, J. M. Veranth, G. S. Yost and C. A. Reilly. Pharmacology/Toxicology, University of Utah, Salt Lake City, UT. #2335 Poster Board Number.....................................534 MECHANISMS OF CHLORINE HYPERSENSITIVITY IN ASTHMA. S. Balakrishna 1 , B. F. Bessac 1 , W. Song 2 , A. I. Caceres 1 , T. Nicola 3 , S. F. Doran 2 , A. Yadav 2 , N. Ambalavanan 3 , S. Matalon 2 and S. E. Jordt 1 . 1 Pharmacology, Yale School of Medicine, New Haven, CT, 2 Anesthesiology, University of Alabama at Birmingham, Birmingham, AL and 3 Pediatrics, University of Alabama at Birmingham, Birmingham, AL. #2336 Poster Board Number.....................................535 BLEOMYCIN-INDUCED LUNG ENDOTHELIAL CYTOSKELETAL REARRANGEMENT IS REGULATED BY THIOL-REDOX. R. B. Patel 1 , L. Sauers 1 , R. M. Uppu 2 and N. L. Parinandi 1 . 1 Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, The Ohio State University College of Medicine, Columbus, OH and 2 Department of Environmental Toxicology, Southern University and A&M College, Baton Rouge, LA. #2337 Poster Board Number.....................................536 HMGB1 IN HYPEROXIA-COMPROMISED HOST ABILITY TO CLEAR PSEUDOMONAS AERUGINOSA PNEUMONIA. V. S. Patel 1 , R. Sitapara 1 , B. Phan 1 , A. Gore 1 , R. Malla 1 and L. L. Mantell 1,2 . 1 Department of Pharmaceutical Sciences, St. John’s University, Jamaica, NY and 2 The Feinstein Institute for Medical Research, North Shore-LIJ Health Science, Manhasset, NY. Wednesday Afternoon, March 9 1:00 PM to 4:30 PM Exhibit Hall Poster Session: Toxicology of the Gulf Oil Spill Chairperson(s): John Wise, University of Southern Maine, Portland, ME. Displayed: 1:00 PM–4:30 PM Author Attended: 1:00 PM–2:45 PM #2338 Poster Board Number.....................................601 A WHOLE BODY INHALATION EXPOSURE SYSTEM FOR THE OIL DISPERSANT COREXIT 9500 WITH PULMONARY FUNCTION RESULTS FROM AN INITIAL SET OF EXPOSURES WITH RATS. W. T. Goldsmith, W. G. McKinney, M. C. Jackson, J. S. Reynolds, J. Cumpston and D. G. Frazer. HELD, CDC/NIOSH, Morgantown, WV. Sponsor: A. Hubbs. #2339 Poster Board Number.....................................602 GENE AND PROTEIN EXPRESSION BIOMARKERS IN FUNGICIDE EXPOSED ZEBRAFISH. D. C. Bencic 1 , R. Wang 1 , A. D. Biales 1 , R. W. Flick 1 , D. L. Villeneuve 2 , G. T. Ankley 2 and D. L. Lattier 1 . 1 U.S. EPA/ORD/NERL/EERD, Cincinnati, OH and 2 U.S. EPA/ORD/NHEERL/ Medical, Duluth, MN. Sponsor: H. Choudhury. #2340 Poster Board Number.....................................603 GENES FROM BONE MARROW OF BENZENE TREATED MICE, COUPLED WITH STRUCTURAL ANALYSIS OF BENZENE AND SIMILAR CHEMICALS IN OIL SPILLS, JOINTLY PREDICT ACUTE MYELOID LEUKEMIA AND POSSIBLE MECHANISM. D. Mitic Potkrajac 1 , G. Apic 1 , F. Bonner 1 and R. B. Russell 2 . 1 Cambridge Cell Networks Ltd., Cambridge, United Kingdom and 2 Cell Networks, University of Heidelberg, Heidelberg, Germany. Sponsor: P. Hewitt. 322 Education-Career Development Sessions Exhibitor Hosted Sessions Featured Sessions Historical Highlights Informational Sessions Platform Sessions
Society of Toxicology 2011 Program Description (Continued) Abstract # #2341 Poster Board Number.....................................604 CHEMICAL DISPERSANTS USED IN THE GULF OF MEXICO ARE CYTOTOXIC AND GENOTOXIC TO HUMAN SKIN FIBROBLASTS. J. Wise 1,2 , S. Wise 1,2,3 , H. Xie 1,2,3 and J. P. Wise 1,2,3 . 1 Wise Laboratory of Environmental and Genetic Toxicology, University of Southern Maine, Portland, ME, 2 Maine Center for Toxicology and Environmental Health, University of Southern Maine, Portland, ME and 3 Department of Applied Medical Science, University of Southern Maine, Portland, ME. #2342 Poster Board Number.....................................605 DEVELOPING A WHALE CELL LINE AT SEA TO EVALUATE THE CYTOTOXICITY AND GENOTOXICITY OF CHEMICAL DISPERSANTS USED IN THE GULF OF MEXICO OIL CRISIS. C. F. Wise 1,2,4 , M. Braun 1,2,4 , J. P. Wise 1,2,4 , S. S. Wise 1,2,3 , I. Kerr 2,4 , H. Xie 1,2,3 and J. P. Wise 1,2,3 . 1 Wise Laboratory of Environmental and Genetic Toxicology, University of Southern Maine, Portland, ME, 2 Maine Center for Toxicology and Environmental Health, University of Southern Maine, Portland, ME, 3 Department of Applied Medical Science, University of Southern Maine, Portland, ME and 4 Ocean Alliance, Lincoln, MA. Wednesday Afternoon, March 9 1:00 PM to 4:30 PM Exhibit Hall Poster Session: Endocrine Toxicology Chairperson(s): Tammy Stoker, U.S. EPA, Research Triangle Park, NC. Displayed: 1:00 PM–4:30 PM Author Attended: 2:45 PM–4:30 PM #2343 Poster Board Number.....................................614 BONE HOMEOSTASIS IS NOT ALTERED IN MCHR1-DEFICIENT MICE. B. Gemzik 1 , J. A. Tamasi 2 , J. J. Devenny 2 , B. J. Murphy 2 , W. N. Washburn 3 and B. D. Car 1 . 1 Discovery Toxicology, Bristol-Myers Squibb Company, Princeton, NJ, 2 Discovery Biology, Bristol-Myers Squibb Company, Princeton, NJ and 3 Discovery Chemistry, Bristol- Myers Squibb Company, Princeton, NJ. #2344 Poster Board Number.....................................615 A NOVEL SENSITIVE AND SELECTIVE REAL-TIME CELLULAR ASSAY FOR DETECTION OF ENDOCRINE DISRUPTORS USING NATIVE ENDOCRINE SIGNALING PATHWAYS. C. Jin 1 , Y. Abassi 1 , X. Xu 1 , X. Wang 1 , W. Zhang 2 and S. Gabos 2 . 1 Acea Biosciences, San Diego, CA and 2 Alberta Health and Wellness, Edmonton, AB, Canada. Sponsor: M. Lo. #2345 Poster Board Number.....................................616 THE IMPACT OF EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITION ON ENERGY HOMEOSTASIS. M. Biggs 1 , D. Threadgill 2 , T. Ghashghaei 3 and T. Lee 4 . 1 Toxicology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2 Genetics, North Carolina State University, Raleigh, NC, 3 Department of Molecular and Biomedical Sciences, North Carolina State University, Raleigh, NC and 4 Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC. Abstract # #2346 Poster Board Number.....................................617 SCIENTIFICALLY RELEVANT INFORMATION TO EVALUATE THE ENDOCRINE DISRUPTING POTENTIAL OF ISOPHORONE. N. M. Berdasco and D. R. Geter. Toxicology and Environmental Research and Consulting, The Dow Chemical Company, Midland, MI. #2347 Poster Board Number.....................................618 EXENATIDE AND SITAGLIPTIN: THEIR ROLE IN AUTOPHAGOSOME REGULATED TOXICITY IN PANCREATITIS. R. Rouse, L. Zhang and D. A. Volpe. U.S. FDA, Silver Spring, MD. #2348 Poster Board Number.....................................619 IMPROVING THE IN VIVO PREDICTIVE VALUE OF THE ER-CALUX BIOASSAY BY COMBINING IN VITRO ESTROGENICITY RESULTS WITH KINETIC CHARACTERISTICS OF ESTROGENIC COMPOUNDS. W. Brand 1 , A. Punt 1,2 , A. J. Murk 2 , M. Schriks 1 , A. P. van Wezel 1 and M. B. Heringa 1 . 1 KWR Watercycle Research Institute, Nieuwegein, Netherlands and 2 Division of Toxicology, Wageningen University, Wageningen, Netherlands. #2349 Poster Board Number.....................................620 PCB-153 AND BDE-47 INCREASE THYROXINE (T ) CATABOLISM IN RAT 4 AND HUMAN HEPATOCYTES. V. M. Richardson 1,2 and M. J. DeVito 3 . 1 ORD/NHEERL/ ISTD, U.S. EPA, Research Triangle Park, NC, 2 Curriculum in Toxicology, University of North Carolina at Chapel Hill, Chapel Hill, NC and 3 Toxicology Branch, NIEHS/NTP, Research Triangle Park, NC. #2350 Poster Board Number.....................................621 TRICLOSAN DECREASES RAT THYROXINE: MODE-OF-ACTION, DEVELOPMENTAL SUSCEPTIBILITY AND HUMAN RELEVANCE. K. B. Paul 1,2 , J. M. Hedge 2 , S. O. Simmons 2 , M. J. DeVito 3,1 and K. M. Crofton 2,1 . 1 Toxicology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2 Integrated Systems Toxicology Division, NHEERL, ORD, U.S. EPA, Research Triangle Park, NC and 3 NTP, NIEHS, Research Triangle Park, NC. #2351 Poster Board Number.....................................622 EVALUATION OF SUBSTANCES ROUTINELY TAKEN IN EVERYDAY LIFE IN THE H295R STEROIDOGENESIS ASSAY. H. Tinwell, S. Colombel and R. Bars. Research Toxicology, Bayer SAS, Sophia Antipolis Cedex, France. #2352 Poster Board Number.....................................623 BISPHENOL A DISRUPTS STEROIDOGENIC PATHWAYS AND ADRENAL AND SEX HORMONE SECRETION IN THE HUMAN ADRENOCORTICAL H295R CELL LINE. A. Oskarsson 1 ,. Ohlsson 1 , C. Jansson 2 and E. Ullerås 1 . 1 Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, Uppsala, Sweden and 2 Department of Aquatic Sciences and Assessment, Swedish University of Agricultural Sciences, Uppsala, Sweden. Wednesday Poster Sessions Regional Interest Session Roundtable Sessions Symposium Sessions Thematic Sessions Workshop Sessions 323
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50 th Anniversary Annual Meeting &
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Scientific Program Overview A page
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9:00 AM-12:30 PM POSTER SESSionS
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March 6-10, 2011 Walter E. Washingt
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Celebration Activities Historical H
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of the Society Regional Chapter Yea
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SOT Presidents 1961-2011 1966 1967
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The SOT Council Thanks and Recogniz
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of the Past 50 Years 2003 Michael D
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Toxicological Sciences The Official
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2011 SOT 50 th Anniversary Featured
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Society of Toxicology 2011 ToxExpo
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Creating a Safer and Healthier Worl
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Society of Toxicology 2011 General
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SOT Job Bank YOUR RECRUITMENT AND E
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Society of Toxicology 2011 SOT 2011
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Society of Toxicology 2011 Recognit
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Society of Toxicology 2011 Student
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Society of Toxicology 2011 Outreach
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Society of Toxicology 2011 2010-201
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Society of Toxicology 2011 Elected
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