Program - Society of Toxicology

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50 th Anniversary Annual Meeting and ToxExpo Program Description (Continued) Wednesday Abstract # Abstract # #1918 Poster Board Number.....................................346 INTEGRATION OF PIG-A, MICRONUCLEUS, CHROMOSOME ABERRATION, AND COMET ASSAY ENDPOINTS IN A 28-DAY RODENT TOXICITY STUDY WITH 4-NITROQUINOLINE-1-OXIDE (4NQO). M. McKeon, H. Chen, T. E. Lawlor, H. Murli, D. J. Roberts, A. Thakur, Y. Xu and L. F. Stankowski. Covance Laboratories, Inc., Vienna, VA. #1919 Poster Board Number.....................................347 COMPUTERIZED ARRHYTHMIA DETECTION IN LARGE TELEMETERED ANIMALS: A NOVEL STRATEGY TO ASSESS DRUG LIABILITIES. R. Mikaelian 1 , S. Authier 1,3 , F. Koeppel 2 , F. Rossi 2 , D. Labarre 2 , S. Fournier 1 and E. Troncy 3 . 1 Laboratory Research Inc., Laval, QC, Canada, 2 Notocord, Paris, France and 3 Faculty of Veterinary Medicine, University of Montréal, St. Hyacinthe, QC, Canada. Sponsor: K. Draper. #1920 Poster Board Number.....................................348 HOW TO IMPROVE SENSITIVITY OF RESPIRATORY SAFETY PHARMACOLOGY STUDIES IN CYNOMOLGUS MONKEYS USING IMPEDANCE MONITORED BY IMPLANTABLE TELEMETRY: THE USE OF SUPER-INTERVALS. F. Duguay 1 , S. Authier 1,2 , S. Fournier 1 and B. Moon 3 . 1 Laboratory Research Inc., Laval, QC, Canada, 2 Faculty of Veterinary Medicine, University of Montréal, St. Hyacinthe, QC, Canada and 3 Data Science International, St. Paul, MN. Sponsor: K. Draper. #1921 Poster Board Number.....................................349 RESPIRATORY SAFETY PHARMACOLOGY MONITORING IN CONSCIOUS GÖTTINGEN MINIPIGS: QUALIFICATION OF A NEW MODEL. C. Ponzi 1 , J. Gervais 1,2 , E. Troncy 2 and S. Authier 1,2 . 1 Laboratory Research Inc., Laval, QC, Canada and 2 Faculty of Veterinary Medicine, University of Montréal, St. Hyacinthe, QC, Canada. Sponsor: K. Draper. #1922 Poster Board Number.....................................350 SUBCUTANEOUS LOCAL TOLERANCE FOR BIOLOGIC DRUG DEVELOPMENT: COMPARISON OF TWO APPROACHES. S. Fleming-Weis 1 , L. M. Diehl 2 , D. Aleksandrowicz 1 , J. Morrow 1 , K. J. Zokowski 4 , K. Ishida 1 , L. E. Beebe 1 , J. M. Pletcher 3 , W. P. Davis 4 and J. B. Clarke 1 . 1 Pharmacotoxicology, Biogen Idec, Cambridge, MA, 2 Toxicology, Charles River Laboratories, Spencerville, OH, 3 Pathology Associates, Charles River Laboratories, Frederick, MD and 4 Comparative Pathology, Biogen Idec, Cambridge, MA. #1923 Poster Board Number.....................................351 CYNOMOLGUS MONKEYS: FACTORS AND ISSUES FOR CONSIDERATION IN THE SELECTION OF SEXUALLY MATURE MALES AND FEMALES FOR PRECLINICAL SAFETY STUDIES. D. Mitchell, H. Palmer, R. Davis and C. Chesher. Safety Assessment, Huntingdon Life Sciences, Cambridgeshire, United Kingdom. #1924 Poster Board Number.....................................352 SERIAL COLLECTION OF CEREBROSPINAL FLUID VIA A SURGICALLY OR PERCUTANEOUSLY IMPLANTED CATHETER IN CYNOMOLGUS MONKEYS. J. K. Herman, R. Avery, M. Taschwer, P. Love, J. Fohey, M. Abdelhameed and W. Meier. Nonclinical Safety Assessment, Covance Laboratories, Madison, WI. #1925 Poster Board Number.....................................353 TEMPERATURE REGULATION AND THE ASSESSMENT OF TOXICITY. K. L. Hastings 1 and M. D. Green 2 . 1 Corporate Regulatory Affairs, sanofi-aventis, Bethesda, MD and 2 OVRR, DVRPA, U.S. FDA, Bethesda, MD. #1926 Poster Board Number.....................................354 APPLICATION OF THE DRIED BLOOD SPOT TECHNIQUE IN THE BIOANALYSIS OF SULPIRIDE. R. Forster, R. Michaud, S. Laurent and T. Ameller. CIT, EVREUX Cedex, France. #1927 Poster Board Number.....................................355 INTRAVITREOUS ADMINISTRATION IN THE RABBIT AND MINIPIG. R. Forster, V. Haag, J. Legrand and B. Palate. CIT, EVREUX Cedex, France. #1928 Poster Board Number.....................................356 ASSESSMENT OF COMMON PRECLINICAL VEHICLE FORMULATIONS USED IN DRUG DISCOVERY BY MAGNETIC RESONANCE SPECTROSCOPY (MRS). R. Sriram and S. Liachenko. Pfizer Inc., Groton, CT. Sponsor: M. Paule. #1929 Poster Board Number.....................................357 DEVELOPMENT AND VALIDATION OF A PHARMACOKINETIC LIGAND BINDING- ASSAY FOR THE DETECTION OF A HUMANIZED THERAPEUTIC IN MULTIPLE SPECIES. A. Neaga, Y. Boyle-Holmes, J. E. Coash, Y. Q. Xiao and L. D. Albee. Department of Immunology, MPI Research, Mattawan, MI. Sponsor: A. Faqi. #1930 Poster Board Number.....................................358 A THOROUGH CHARACTERIZATION OF THE THE FREQUENCY RESPONSE OF VARIOUS IN VIVO BLOOD PRESSURE MEASUREMENT TECHNOLOGIES. J. P. Kroehle, J. Grenwis and R. Sarazan. DSI, St. Paul, MN. #1931 Poster Board Number.....................................359 OPTIMIZATION OF INTRAVENOUS CYNOMOLGUS MONKEY INFUSION VIA VASCULAR ACCESS PORT. A. M. Brooks and A. N. Alexander. Department of Toxicology, Covance Inc., Madison, WI. #1932 Poster Board Number.....................................360 CONTROLLING FOR CROSS CONTAMINATION IN TOXICOLOGY STUDIES. M. M. Peet, C. J. Dean, C. Diabo, E. St. Peter and S. E. Boley. General Toxicology, MPI Research, Mattawan, MI. 286 Education-Career Development Sessions Exhibitor Hosted Sessions Featured Sessions Historical Highlights Informational Sessions Platform Sessions
Society of Toxicology 2011 Program Description (Continued) Abstract # Wednesday Morning, March 9 9:00 AM to 12:30 PM Exhibit Hall Poster Session: Risk Assessment: Conceptual Constructs and Current Controversies Chairperson(s): David Eastmond, University of California Riverside, Riverside, CA, and Julie Goodman, Gradient Corporation, Cambridge, MA. Displayed: 9:00 AM–12:30 PM Author Attended: 11:00 AM–12:30 PM #1933 Poster Board Number.....................................407 PATHOLOGICAL LESIONS OF RODENTS LACKING HUMAN RELEVANCE IN RISK ASSESSMENT. M. A. Mulla, R. Nirogi, S. Jana, V. Goyal and S. Pandey. Toxicology, Suven Life Sciences Limited, Hyderabad, Andhra Pradesh, India. Sponsor: V. Reddy. #1934 Poster Board Number.....................................408 AN EVALUATION OF FACTORS FOR CLASSIFYING A CHEMICAL AS INDUCING CANCER IN EITHER RODENTS OR HUMANS VIA A MUTAGENIC MODE OF ACTION USING A WEIGHT OF EVIDENCE APPROACH. D. A. Eastmond 1 , S. V. Vulimiri 2 and B. Sonawane 2 . 1 Environmental Toxicology Program, University of California Riverside, Riverside, CA and 2 National Center for Environmental Assessment, U.S. EPA, Washington, D.C. #1935 Poster Board Number.....................................409 A WEIGHT-OF-EVIDENCE EVALUATION OF ASBESTOS EXPOSURE AND MESOTHELIOMA RISK AMONG ELECTRICIANS. M. Peterson, L. A. Bailey, D. G. Dodge, J. E. Goodman and P. A. Valberg. Gradient, Seattle, WA. #1936 Poster Board Number.....................................410 STATE-OF-THE-SCIENCE ASSESSMENT OF NON-FIBROUS AMPHIBOLE EXPOSURE: IS THERE A HEALTH HAZARD? C. A. Williams, R. Adams, D. Podraza, C. Simmons, T. Rose and L. Dell. Environ International, Tampa, FL. #1937 Poster Board Number.....................................411 ARSENIC SPECIATION IN AIR: AN EVALUATION OF THE CURRENT STATE OF KNOWLEDGE AND RESEARCH NEEDS. A. S. Lewis 1 , K. R. Reid 1 , M. C. Pollock 1 and S. Campleman 2 . 1 Gradient, Cambridge, MA and 2 Electric Power Research Institute, Palo Alto, CA. #1938 Poster Board Number.....................................412 THE ROLE OF IRON IN THE REDUCED BIOAVAILABILITY OF ARSENIC IN SOIL. V. L. Mitchell 1 , C. N. Alpers 2 , N. T. Basta 3 , T. Burlak 4 , S. W. Casteel 5 , R. L. Fears 1 , A. L. Foster 6 , C. S. Kim 7 , P. A. Myers 1 and E. Petersen 8 . 1 Toxic Substances Control, Cal EPA, Sacramento, CA, 2 U.S. Geological Survey, Sacramento, CA, 3 Ohio State University, Columbus, OH, 4 California State University, Sacramento, CA, 5 University of Missouri, Columbia, MO, 6 U.S. Geological Survey, Menlo Park, CA, 7 Chapman University, Orange, CA and 8 University of Utah, Salt Lake City, UT. Abstract # #1939 Poster Board Number.....................................413 ARSENIC RISK ASSESSMENT FOLLOWING REMOVAL OF CONSTRAINING FACTORS— REFERENCE POPULATION AND MEDIAN EXPOSURE METRIC. S. H. Lamm 1,2 , S. Robbins 1 , J. Lu 3 , R. Chen 4 and M. Feinleib 5 . 1 Epidemiology, Consultants in Epidemiology and Occupational Health (CEOH), Washington, D.C., 2 Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 3 Mathematics, American University, Washington, D.C., 4 Center for New Design in Learning and Scholarship, Georgetown University, Washington, D.C. and 5 Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. Sponsor: J. Tsuji. #1940 Poster Board Number.....................................414 INTERPRETING NHANES DATA ON ARSENIC LEVELS IN URINE USING BIOMONITORING EQUIVALENTS. C. R. Kirman 1 , S. M. Hays 2 , L. L. Aylward 3 and R. Schoeny 4 . 1 Summit Toxicology LLP, Orange, OH, 2 Summit Toxicology LLP, Lyons, Co., 3 Summit Toxicology LLP, Falls Church, VA and 4 U.S. EPA, Washington, D.C. #1941 Poster Board Number.....................................415 A REVIEW OF THE POTENTIAL ASSOCIATION BETWEEN CHILDHOOD LEUKEMIA AND BENZENE. D. Pyatt 1,2,3 and S. Hays 1,2 . 1 Summit Toxicology, Superior, Co., 2 School of Public Health, University of Colorado, Denver, CO and 3 MTEHS Program, University of Colorado, Denver, CO. #1942 Poster Board Number.....................................416 USE OF IN VITRO BIOACCESSIBILITY ANALYSIS, HUMAN HEALTH RISK ASSESSMENT, AND URINARY ARSENIC MEASUREMENTS TO ASSESS EXPOSURE AND RISKS OF CHILDREN IN A NORTHERN CANADIAN SMELTER COMMUNITY. E. Sigal, A. M. Safruk and C. M. Bacigalupo. Intrinsik, Mississauga, ON, Canada. #1943 Poster Board Number.....................................417 BLOOD AND URINARY ELIMINATION KINETICS OF BISPHENOL A IN HUMANS FOLLOWING DIETARY EXPOSURE. J. G. Teeguarden 1 , R. Gunawan 1 and A. Calafat 2 . 1 Biological Monitoring and Modeling, Pacific Northwest National Laboratory, Richland, WA and 2 Organic Analytical Toxicology Branch, National Center for Environmental Health, Centers for Disease Control, Atlanta, GA. #1944 Poster Board Number.....................................418 WEIGHT-OF-EVIDENCE EVALUATION OF FORMALDEHYDE EXPOSURE AND LEUKEMIA RISK. J. E. Goodman, D. B. Mayfield, L. A. Bailey and L. R. Rhomberg. Gradient, Cambridge, MA. #1945 Poster Board Number.....................................419 WEIGHT-OF-EVIDENCE EVALUATION OF NON-CANCER ANIMAL AND HUMAN STUDY OUTCOMES AFTER FORMALDEHYDE EXPOSURE. S. L. Makris, T. F. Bateson, D. DeVoney, S. Y. Euling, B. S. Glenn and K. C. Raffaele. ORD, NCEA, U.S. EPA, Washington, D.C. Wednesday Poster Sessions Regional Interest Session Roundtable Sessions Symposium Sessions Thematic Sessions Workshop Sessions 287
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50 th Anniversary Annual Meeting &
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Scientific Program Overview A page
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9:00 AM-12:30 PM POSTER SESSionS
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March 6-10, 2011 Walter E. Washingt
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Celebration Activities Historical H
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of the Society Regional Chapter Yea
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SOT Presidents 1961-2011 1966 1967
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The SOT Council Thanks and Recogniz
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of the Past 50 Years 2003 Michael D
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Thank You to the following individu
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Toxicological Sciences The Official
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2011 SOT 50 th Anniversary Featured
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Society of Toxicology 2011 ToxExpo
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Creating a Safer and Healthier Worl
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SOT Job Bank YOUR RECRUITMENT AND E
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Society of Toxicology 2011 SOT 2011
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Society of Toxicology 2011 Author I
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Society of Toxicology 2011 2010-201
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