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50 th Anniversary Annual Meeting and ToxExpo Program Description (Continued) MONday Abstract # Abstract # Monday Morning, March 7 9:30 AM to 12:30 PM Exhibit Hall Poster Session: Genotoxicity Chairperson(s): Lynn Pottenger, Dow Chemical Company, Midland, MI. Displayed: 9:30 AM–12:30 PM Author Attended: 9:30 AM–11:00 AM #315 Poster Board Number.....................................613 EVALUATION OF MUTAGENICITY, CHROMOSOME BREAKAGE, AND DNA DAMAGE BY PIG-A, MICRONUCLEUS AND COMET ASSAYS IN 28-DAY REPEATED DOSE TOXICITY STUDIES. J. Shi 1 , M. Paranjpe 1 , S. W. Bruce 1 , T. Kelley 1 , S. Springer 1 , J. Sly 1 , M. Klug 1 , M. Arevaro 1 , S. Atta-Safoh 1 , F. Debelie 1 , L. Krsmanovic 1 , P. Sareen 1 and S. Dertinger 2 . 1 BioReliance Corporation, Rockville, MD and 2 Litron Laboratories, Rochester, NY. #316 Poster Board Number.....................................614 A NOVEL HIGH-THROUGHPUT IN VITRO MNT PROFILING ASSAY FOR SUSPENSION CELLS. S. Kirchner, M. Prummer, S. Marget- Müller, J. Muller, C. McGinnis, K. Kolaja, R. Werder, K. Christensen, S. Zoffmann, T. Enderle, R. Rietmann, D. Vögelin, P. Iaiza, C. Fattinger and T. Weiser. F. Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland. #317 Poster Board Number.....................................615 THE HUNT FOR MISLEADING POSITIVES: CAN NON-GENOTOXIC REGULATION OF GADD45A INTERFERE WITH GREENSCREEN HC? C. Topham 2 and R. Walmsley 1,2 . 1 Life Sciences, University of Manchester, Manchester, United Kingdom and 2 Gentronix Ltd., Manchester, United Kingdom. #318 Poster Board Number.....................................616 COMPARATIVE DNA DAMAGE AND CHRONIC LIVER TOXICITY OF BENZO[A] PYRENE IN TWO POPULATIONS OF THE ATLANTIC KILLIFISH (FUNDULUS HETEROCLITUS) WITH DIFFERENT EXPOSURE HISTORIES. R. Di Giulio 1 , D. Jung 2,1 and L. Wills 3,1 . 1 Nicholas School of the Environment, Duke University, Durham, NC, 2 Department of Physiology, Dartmouth Medical School, Lebanon, NH and 3 Medical University of South Carolina, Charleston, SC. #319 Poster Board Number.....................................617 DNA DAMAGE CAUSED BY TRICYCLIC ANTIDEPRESSANTS. E. A. Korobkova and A. K. Williams. Science, John Jay College of Criminal Justice, New York. Sponsor: B. Shane. #320 Poster Board Number.....................................618 EVALUATION OF DIRECT AND INDIRECT DNA DAMAGE INDUCED BY OCHRATOXIN A IN CHO AND TK6 CELLS USING THE COMET ASSAY. R. Ali 1,2 , J. G. Shaddock 2 , W. Ding 2 , J. A. Bhalli 2 , Q. M. Khan 1 and R. H. Heflich 2 . 1 Environmental Biotechnology Division, National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan and 2 Division of Genetic and Molecular Toxicology, National Center for Toxicological Research/U.S. FDA, Jefferson, AR. Sponsor: M. Moore. #321 Poster Board Number.....................................619 THE IN VIVO RAT COMET ASSAY OF DIETHYLNITROSAMINE: RELEVANCE BETWEEN CARCINOGENESIS AND DNA DAMAGE IN THE TARGET ORGANS. Y. Uematsu, C. Hirogaki, H. Adachi, K. Kijima, T. Yamada, Y. Michimae, I. Matsumoto, T. Koujitani, H. Oishi, H. Funabashi and T. Seki. Safety Research Laboratory, Dainippon Sumitomo Pharmacology Co., Ltd., Suita-City, Osaka, Japan. #322 Poster Board Number.....................................620 OPTIMAL CONDITIONS FOR PERFORMANCE OF THE COMET ASSAY USING A THREE-DIMENSIONAL HUMAN EPIDERMAL MODE. H. Kojima and M. Hojyo. Division of Pharmacology, National Institute of Health Sciences, Tokyo, Japan. #323 Poster Board Number.....................................621 GENOTOXICITY OF STYRENE- ACRYLONITRILE TRIMER IN WEANLING F344 RATS. R. S. Chhabra 1 , C. A. Hobbs 2 , L. Recio 2 , J. Winters 2 , K. Shepard 2 , P. Allen 2 , M. Prajapati 2 , M. Streicker 3 and K. L. Witt 1 . 1 National Toxicology Program, NIEHS, Research Triangle Park, NC, 2 Genetic and Molecular Toxicology, ILS, Inc., Research Triangle Park, NC and 3 Investigative Toxicology, ILS, Inc., Research Triangle Park, NC. #324 Poster Board Number.....................................622 THE EVALUATION OF MN AND SCE FREQUENCIES AND OXIDATIVE STRESS STATUS OF HOSPITAL STAFF OCCUPATIONALLY EXPOSED TO LOW DOSES OF IONIZING RADIATION. DOES THE LOW DOSE STIMULATE DEFENSE STATUS? A. Aydin 1 , A. Eken 2 , O. Erdem 2 , C. Akay 2 , B. Soykut 2 , A. Sayal 2 and I. Somuncu 3 . 1 Toxicology, Yeditepe University, Faculty of Pharmacy, Istanbul, Turkey, 2 Toxicology, Gulhane Military Medical Academy, Ankara, Turkey and 3 Radiology, Gulhane Military Medical Academy, Ankara, Turkey. Sponsor: A. Karakaya. #325 Poster Board Number.....................................623 GENOTOXICITY TESTING OF GATIFOLIA (GUM GHATTI). C. A. Hobbs 1 , C. Swartz 1 , R. Maronpot 2 , J. Davis 3 , M. Prajapati 1 , K. Shepard 1 , P. Allen 1 , C. Lentz 1 , P. Garibaldi 1 , L. Recio 1 and S. Hayashi 4 . 1 Genetic and Molecular Toxicology, ILS, Inc., Research Triangle Park, NC, 2 Maronpot Consulting LLC, Raleigh, NC, 3 Investigative Toxicology, ILS, Inc., Research Triangle Park, NC and 4 San-Ei Gen F.F.I., Inc., Osaka, Japan. 142 Education-Career Development Sessions Exhibitor Hosted Sessions Featured Sessions Historical Highlights Informational Sessions Platform Sessions
Society of Toxicology 2011 Program Description (Continued) Abstract # #326 Poster Board Number.....................................624 COMPARISON OF TWO DIFFERENT TEST PROTOCOLS FOR AN ACCURATE ASSESSMENT OF THE IN VITRO MICRONUCLEUS TEST IN HUMAN LYMPHCYTES. S. Bohnenberger, A. H. Poth, C. Hall and W. Voelkner. Genetic and Alternative Toxicology, Harlan Cytotest Cell Research GmbH, Rossdorf, Germany. #327 Poster Board Number.....................................625 TOXICOLOGICAL EVALUATION OF COMPLEX MIXTURES FROM RESIDUES USED ON AGRICULTURAL LAND APPLICATION. A. Pillco 1,2 , E. de la Peña 1 and M. Hazen 3 . 1 Centro de Ciencias Medioambientales, Consejo Superior de Investigaciones Científicas, Madrid, Spain, 2 Facultad de Bioquímica, Universidad Mayor de San Andrés, La Paz, Bolivia and 3 Departamento de Biología, Universidad Autónoma de Madrid, Madrid, Spain. Sponsor: E. Vilanova. #328 Poster Board Number.....................................626 CYTOTOXIC AND GENOTOXIC EFFECTS OF MAGNETITE ON HUMAN A549 LUNG CELLS IN VITRO–INFLUENCE OF ROS, JNK, AND NF-κB. M. Könczöl 1 , V. Mersch- Sundermann 1 , S. Ebeling 2 , E. Goldenberg 3 , B. Grobéty 4 , R. Gieré 3 , I. Merfort 2 , B. Rothen- Rutishauser 5 and R. Gminski 1 . 1 Department of Environmental Health Sciences, University Medical Center Freiburg, Freiburg, Germany, 2 Department of Pharmaceutical Biology, University Freiburg, Freiburg, Germany, 3 Department of Geosciences, University Freiburg, Freiburg, Germany, 4 Institute of Geosciences, University Fribourg, Fribourg, Switzerland and 5 Institute of Anatomy, University Bern, Bern, Switzerland. Sponsor: J. Pauluhn. #329 Poster Board Number.....................................627 THE PROTECTIVE EFFECT OF TROLOX AND RESVERATROL ON DNA DAMAGE INDUCED BY CYCLOPHOSPHAMIDE AND TAMOXIFEN IN HUMAN LEUKOCYTES. R. Naravaneni, S. Sharma, D. Bhaumick and R. D. Mehta. Genetic Toxicology, PBR Laboratories Inc., Edmonton, AB, Canada. #330 Poster Board Number.....................................628 EVALUATION OF THE GENOTOXICITY OF 1, 2-DICHLOROETHANE (EDC). D. O. Johns 2 , M. R. Gwinn 1 , T. F. Bateson 1 and K. Z. Guyton 1 . 1 Office of Research & Development, U.S. EPA, Washington, D.C. and 2 Office of Research & Development, U.S. EPA, Research Triangle Park, NC. #331 Poster Board Number.....................................629 INTEGRATION OF PIG-A, MICRONUCLEUS, CHROMOSOME ABERRATION, AND COMET ASSAY ENDPOINTS INTO RODENT TOXICITY STUDIES WITH 4-NITROQUINOLINE-1-OXIDE (4NQO): EFFECT OF DOSE FRACTIONATION ON GENOTOXIC RESPONSES. L. F. Stankowski, D. J. Roberts, H. Chen, T. E. Lawlor, M. McKeon, H. Murli, A. Thakur and Y. Xu. Covance Laboratories, Inc., Vienna, VA. Abstract # #332 Poster Board Number.....................................630 CASE STUDY ON DOSE-RESPONSES FOR MUTAGENICITY AND CLASTOGENICITY INDUCED BY DNA-REACTIVE CHEMICALS. L. H. Pottenger 1 , M. M. Moore 2 , T. Zhou 3 and E. Zeiger 4 . 1 The Dow Chemical Company, Midland, MI, 2 U.S. FDA NCTR, Jefferson, AR, 3 U.S. FDA/CVM, Rockville, MD and 4 Errol Zeiger Consulting, Chapel Hill, NC. #333 Poster Board Number.....................................631 HIGH-THROUGHPUT IN VITRO MICRONUCLEUS ASSAY: AUTOMATED SCORING OF 384-WELL PLATES. S. Bryce, S. Avlasevich and S. Dertinger. Litron Laboratories, Rochester, NY. #334 Poster Board Number.....................................632 PHOTO-CLASTOGENICITY TESTING IN HUMAN PERIPHERAL BLOOD LYMPHOCYTES. S. Roy, H. Murli, M. Chan, L. F. Stankowski Jr. and T. Lawlor. Genetic & Molecular Toxicology, Covance Laboratories Inc., Vienna, VA. Sponsor: M. McKeon. #335 Poster Board Number.....................................633 PCB3 METABOLITES INDUCE SPINDLE ABERRATIONS AND REDUCE TUBULIN POLYMERIZATION. S. Flor and G. Ludewig. University of Iowa, Iowa City, IA. #336 Poster Board Number.....................................634 EVALUATION OF THE GENOTOXICITY AND MUTAGENICITY OF THE DYE REACTIVE ORANGE 16. G. R. Oliveira 1 , M. B. Zanoni 2 and D. P. Oliveira 1 . 1 Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto - FCFRP/USP, Ribeirão Preto, São Paulo, Brazil and 2 Departamento de Química Analítica, Instituto de Química - UNESP, Araraquara, São Paulo, Brazil. #337 Poster Board Number.....................................635 COMPARISON OF ANEUPLOIDIES OF CHROMOSOMES X, Y, AND 21 IN THE PERIPHERAL BLOOD LYMPHOCYTES AND SPERM CELLS OF WORKERS EXPOSED TO BENZENE. Z. Ji 1 , R. H. Weldon 1 , F. Marchetti 2 , H. Chen 1 , G. Li 3 , C. Xing 2,3 , E. Kurtovich 1 , S. Young 1 , T. E. Schmid 2 , S. Waidyanatha 4 , S. Rappaport 1 , A. J. Wyrobek 2 , L. Zhang 1 and B. Eskenazi 1 . 1 School of Public Health, University of California at Berkeley, Berkeley, CA, 2 Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 3 China CDC, Beijing, China and 4 National Toxicology Program, NIEHS, Research Triangle Park, NC. #338 Poster Board Number.....................................636 IN VITRO GENOTOXIC MECHANISMS OF ARSENIC TRIOXIDE IN HUMAN HEPATOCELLULAR CARCINOMA (HEPG2) CELLS: INVOLVEMENT IN OXIDATIVE STRESS. E. T. Brown, C. G. Yedjou and P. B. Tchounwou. Jackson State University, Jackson, MS. MONday Poster Sessions Regional Interest Session Roundtable Sessions Symposium Sessions Thematic Sessions Workshop Sessions 143
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50 th Anniversary Annual Meeting &
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Scientific Program Overview A page
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9:00 AM-12:30 PM POSTER SESSionS
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March 6-10, 2011 Walter E. Washingt
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Celebration Activities Historical H
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of the Society Regional Chapter Yea
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SOT Presidents 1961-2011 1966 1967
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Toxicological Sciences The Official
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SOT Job Bank YOUR RECRUITMENT AND E
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Society of Toxicology 2011 Author I
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Society of Toxicology 2011 2010-201
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Society of Toxicology 2011 Elected
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