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109 Association between Johne’s Disease Milk ELISA Test Result<br />

<strong>and</strong> Milk Production <strong>and</strong> Breed in Canadian Dairy Cows<br />

U. Sorge 1 , D. Kelton 1 , W. Sears 1 , J. Jansen 2 , A. Godkin 2 , R. Cantin 3<br />

1<br />

University of Guelph, Department of Population Medicine, Guelph,<br />

Canada<br />

2<br />

OMAFRA, Department of Population Medicine, Fergus, Canada<br />

3<br />

CanWest DHI, Guelph, Canada<br />

Johne’s Disease is often described as a production limiting disease. The<br />

objective of this study was to quantify the difference in milk production<br />

of JD milk ELISA positive cows <strong>and</strong> test negative cows, as well as to<br />

evaluate variations in test results due to breed. The test day information<br />

from 4,390 cows from 80 CanWest DHI herds in Ontario was available<br />

for this analysis. The cows were tested between March 2005 <strong>and</strong> March<br />

2006 with the AntelBio Johne’s Milk ELISA. A mixed model was<br />

fitted to investigate the association of a positive milk ELISA test with<br />

the estimated cumulative 305 day milk production. Only factors with a<br />

p-value 12 months of age) seropositive<br />

(ELISA) for MAP in a national whole herd serosurvey. Control herds<br />

were matched to case herds on the basis of the year of diagnosis of<br />

PTB in the case herds. Statistical analyses were performed using uni<strong>and</strong><br />

multivariate conditional logistic regression with the herd as the<br />

experimental unit. Factors relating to disease history, herd size,<br />

neonatal feeding <strong>and</strong> management <strong>and</strong> grassl<strong>and</strong> management were<br />

found to be significantly associated with herd PTB status (P

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