Oral and Poster Abstracts

Scotland, cryptosporidiosis appears in young calves of 5 to 15 days
of age, with a putrid-odor mucoid diarrhea. The differential
diagnosis is based on the presence of oocysts revealed at the lab.
Clinical cryptosporidiosis generally appears in beef or dairy herds at
the end of the calving period when the pressure of infection is at its
maximum. Curative treatments in calves are few, difficult to use and
often provide poor results. A systematic preventive treatment in
suckling calves is also difficult to carry out owing to the constraint
of treating them preventively once a day during 7 consecutive days.
Moreover, weight loss is often observed. The pregnant Simmental
cows were treated with decoquinate at the rate of 1.25 mg/kg
BW/day over 28 days prior to calving and for 7 days following it. In
these field trials, 120 cows were first treated during two consecutive
pregnancies. In these farms, clinical cryptosporidiosis disappeared
almost totally. The dosage must be strictly adhered to and the body
weight of pregnant cows must not be underestimated (760kg in
Simmental). Also it is important to treat before and after calving,
cows must be grouped according to their calving date, a cow with
delayed calving must be treated till after parturition. Our field trial
confirms other trials already run in France and Spain on Beef cows
and ewes. Treating cows or ewes with decoquinate 4 weeks before
and 1 week after parturition controls cryptosporidiosis in newborn
ruminants.
1165 Evaluation of the Persistent Efficacy of CYDECTIN
(Moxidectin) 10% LA Injectable against Psoroptes ovis in
Naturally Infested Cattle in Belgium
B. Losson1 , R. Hanosset1 , M. Lekimme1 , B. Mignon1 , E. Deroover2 1 University of Liege, Parasitology, Liege, Belgium
2 Fort Dodge Animal Health, Animal Health Department, Brussels,
Belgium
The aim of the study was to evaluate the persistent efficacy of
Cydectin (moxidectin) LA 10% injectable (Cyd. LA) in a herd of
Belgian White and Blue cattle naturally infested with Psoroptes ovis.
The animals were weighed, clinically and parasitologically
examined and divided into two groups of 17 (Group 1- all positive
for P. ovis) and 23 (Group 2 - 20 positive for P. ovis mite) animals.
On day 0, 13 Group 1 animals and 19 Group 2 animals were given a
subcutaneous injection of Cyd. LA at a dosage of 1.0 mg/kg bw (1 ml
/100kg). In each group, 4 animals remained as untreated controls.
Mite counts were performed on days 0, 28, 35, 42, 49, 56, 63, 70 and
77 PT. Mite counts were transformed into mite scores and means
were calculated for each group. In both pens an unexpected result
was achieved as all experimental animals were found to be negative
for live P. ovis mites on day 28 PT. All animals remained negative
for live mites until day 42. On day 46 PT, two seeder animals were
removed from Group 1 and replaced by one clinically affected and
one clinically and parasitologically positive animal. This was not
possible in Group 2. In Group 1, all animals remained negative for
live mites until the end of the trial on day 77 despite the presence of
an actively infested seeder animal; the second seeder animal was
found positive for live mites on day 70. In Group 2, all animals
remained negative for live P. ovis mites until the end of the trial.
This trial indicates that Cyd. LA at a dosage of 1.0 mg/kg bw was
highly efficient against a natural infestation with P. ovis in growing
BWB cattle and was very well tolerated. The fact that all seeder
animals became negative for live P. ovis mites is difficult to explain.
Self cure can be observed but this is unlikely in all control animals.
The high dosage linked with the use of LA moxidectin could be
responsible for the excretion of fairly high amounts of the active
ingredient via the urine, faces and skin secretions. The seeder
animals could be exposed to fairly high doses of moxidectin.
Nevertheless, in Group 1, 2 new seeders animals were introduced;
this challenge was maintained until the end of the experiment (day
77). All skin scrapings remained negative for live mites. In
conclusion, Cyd. LA at a dosage of 1.0 mg/kg bw provided under
field conditions a full protection for at least 77 days in a group of
animals under a P. ovis challenge which was continuous from day 46
onwards.
Key words: Psoroptes ovis, Cydectin LA, lasting effect, cattle
1166 Liver Copper Status in Sheep with Fascioliosis
G. Kojouri 1 , J. Shojai 2 , I. Amani 3
1 Shahrekord University, Clinical Sciences, Shahrekord, Iran
2 Islamic Azad University of Shahrekord, Graduated Veterinary
Student, Shahrekord, Iran
3 School of Veterinary Medicine, Shahrekord University, Student,
Shahrekord, Iran
Fascioliosis is a disease that affects sheep, goats, cattle and many other
species. The flukes also can migrate into the bile ducts or through
hepatic tissue, leaving large anaerobic tracts and may produce anemia,
hypoalbuminaemia, increasing hepatic enzyme and decreasing plasma
ascorbic acid concentration. Liver has a major role on energy and
protein metabolism and many important enzymes synthesis too. To this
respect and to determine the role of parasite on copper status and also
the role of this mineral on parasite survival, liver tissue samples were
taken from 35 healthy and 35 infected slaughtered sheep. Copper
concentration was measured by atomic absorption spectroscopy and
data were statistically analyzed by ANOVA at the level of P