Oral and Poster Abstracts

In Mexico, there is a wide variety of breeds of bovines, goats, sheep
and wild deer, that are either indigenous to the area or imported from
other countries. They are used for the production of meat, milk, for
hunting ranches , in zoos and circuses. Due to injuries and trauma in
the fields, during transportation, fighting and other causes, these
animals suffer various types of fractures of long bones such as
femur, fibula, radius, and also of the metatarsi and metacarpi .The
Faculty of Veterinary Medicine of the National University of
Mexico recieves cases from submitted by veterinary practitioners
from all over the country and also directly from zoos or from animal
owners everywhere in the country. In the last few years we have
been asked to reduce fractures using implants such as plates, screws,
circlage, intramedular pins. In this poster, we present 12 cases
of traumatized animals, 11 of which were treated with implants and
one had to be amputated due to the severity of the injury. The group
included five deer, a wild goat, two bovines (bos taurus) and one bos
indicus,and three hampshire sheep. The procedures were successful
in all the deer and sheep and also in one bos taurus, while in the bos
indicus and one bos taurus of approximately 800 kg and the wild
goat, the procedure was unsuccessful. The male bulls twisted the
plates as soon as they stood on their legs and the wild goat died of
causes unrelated to the surgery. Two of the sheep and the female bos
taurus were implanted with plates and screws and had a good
evolution. In the same way, the deer whose fractures were treated
with Steinman pins had a good recovery. The failures in the bulls
were due to the excess weight. The Steinman pin worked well in
animals whose weight ranged between 35 and 40 kg and the plates
were satisfactory in two sheep that weighed 35 kg and a female bos
taurus that weighed 225 kg. The experience obtained with these
cases makes us conclude that plates should not be used in animals
weighing over 250 kg and that the Steinman pins are very
satisfactory for use in small domestic or wild ruminants f. e. the
white tailed deer, goats, sheep and dama fallow deer.
983 Comparative Efficacy of Flunixine Meglumine in a Tissue
Cage Model of Inflammation
O. Roy 1 , P. Cloet 2 , E. Bénizeau 1 , M. Catala 1 , A. Weingarten 3 ,
C. Maisonneuve 3 , D. Sweeney 3
1 CEBIPHAR, CRO, Fondettes, France
2 Schering Plough Vétérinaire, Levallois Perret, France
3 Schering Plough Animal Health, Summit, United States
The efficacy of Finadyne ® injectable was evaluated for treatment of
induced inflammation of the subcutis in cattle. It was assessed by
comparing in a cross-over designed trial the effect of Finadyne ® on
exudate PGE 2 concentration to that of Metacam ® and 0.9% NaCl
solution. Twelve healthy calves (183.3 ± 39.1 kg) were included in
the study and randomly assigned to three treatment sequences.
Sterile hollow perforated polyethylene balls were surgically
embedded in the subcutis at four distinct sites per animal two weeks
prior to D0. On D0, D21, and D42, an aseptic inflammation of the
subcutis was induced by injecting in three balls per animal 0.5 ml of
a 2% carrageenan solution. Treatment immediately followed. 0.5 ml
of exudate was collected prior to challenge, and 2, 4, 8, 12, 24, 36,
and 48 hours after. Cages were emptied after each collection.
Exudate PGE 2 concentrations were measured using a validated
ELISA kit. Each animal received all three items as treatment
sequentially on D0, D21, and D42. PGE 2 pre-challenge
concentrations were near 0. PGE 2 concentration levels over time
displayed a post-challenge sharp increase, peaked 2 hours after
treatment and gradually decrease, returning to baseline values within
48 hours. Curves were similar over all three periods.PGE 2
concentrations when treated with Finadyne ® or Metacam ® were
consistently lower than those measured when treated with NaCl.
Percent of inhibition was highest at +4 hours after treatment.
Differences (absolute values) with the placebo were significant
throughout the post-treatment period (up to 48 hours) for Finadyne ®
and at +2, 4, 8, and 12 hours after treatment with Metacam ® .
Differences in pre-dose concentrations among calves were
accounted for by dividing post-dose PGE 2 concentrations by predose
PGE 2 concentrations for each calf. Mean PGE 2 concentrations
in the NaCl group were significantly higher compared to those in the
Metacam ® group at 2 and 4 hour, and close to significance at 8, 12,
24 and 36 hours. They were significantly higher than those in the
Finadyne ® group throughout the study. At 36 and 48 hours after
dosing, the mean PGE 2 concentration in the Metacam ® group was
266 XXV. Jubilee World Buiatrics Congress 2008
significantly higher than in the Finadyne ® group. This study shows
that both items inhibit cyclo-oxygenase with a more potent and
residual inhibitory activity of Finadyne ® compared to Metacam ® .
984 A Retrospective Study on 157 Cases of Left Displacement of
Abomasum (LDA) in Some Dairy Farms in IRAN
F. Adibhashemi 1 , S. Bokaie 2
1 Faculty of Veterinary Medicine, University of Tehran, Clinical
Sciences Department, Tehran, Iran
2 Faculty of Veterinary Medicine, University of Tehran, Food hygiene
and Quality Control Department, Tehran, Iran
Displacement of the abomasum is probably the most common
surgical condition of bovine patient. Left displacement of abomasum
is a multi factorial syndrome by many caves. the results and finding
of studies (cause, number of parturition) may be different in different
geographic location.The study were done on 157Dairy cattle with
LDA in some dairy farms in Tehran .The goal of this study is to find
the answer for some questions (age, sex, number of parturition ) .The
results showed that 96.5% of cases were in female and 3.2% in male
sex. The other results were as follows: 2.6% of cases were heifers
25% in first parturition, 7.2% in 2th parturition 35.5% in 3th
parturition, 25% in 4 th parturition 4.6% in 5 th parturition 1.3% of
cases were in before parturition 0.7% in first week after parturition
2.07% in 2 weeks after parturition 50% in 3 weeks after parturition
10.5% in 4 th weeks after parturition 15.8% in 5 th weeks after
parturition 8.06% of cases recovered after surgery completely 5.3%
were culled for some complications 13.7% of cases were culled for
accompany diseases .
Key words: left displacement of abomasum, cattle
985 Comparison of Intranasal Versus Intravenous Lidocaine
Application during Rhinotracheobronchoscopy in Cattle
A. Dadak 1 , S. Franz 2
1 Institute for Pharmacology and Toxicology, Vienna, Austria
2 Clinic for Ruminants, Vienna, Austria
Objectives: Research was done on the efficacy and safety of lidocaine
during endoscopic procedures of the upper respiratory tract in cattle.
Patients and Method: Experiments were performed in healthy non
lactating cows. Eight minutes after intranasal (IN) or intravenous (IV)
application of lidocaine (1.5 mg/kg), both given over a period of 5 min,
rhinotracheobronchoscopy was performed. Experiments were
videotaped for subsequent analysis of behavioural changes. Mean
invasive arterial blood pressure (MABP) and heart rate (HR) were
analysed at specified time points. Blood samples were taken up to 60
min in order to measure serum lidocaine concentrations.
Results: Preliminary data show that lidocaine did not lead to
significant cardiovascular reactions in cattle, neither after IN nor
after IV administration. In the present study absorption of lidocaine
was generally rapid after IN application. During the procedure of
rhinotracheobronchoscopy, HR and MABP increased slightly in all
groups (lidocaine IN, IV and the control groups). Lidocaine
significantly improved the animals’ tolerance during rhinoscopy,
especially when given IN. Insertion of the endoscope into the trachea
was eased in both, the lidocaine IN and the lidocaine IV group.
Discussion and Conclusion: We conclude from our results that
lidocaine is a safe and effective analgesic option for endoscopic
procedures of the upper respiratory tract when given at a dosage of
1.5 mg/kg. On the basis of our results we favour intranasal over
intravenous application of lidocaine for rhinotracheobronchoscopy
in cattle.
Key words: cattle, endoscopy, lidocaine, application
986 Study of Toxicological Effects of Epidural Neostigmine
Methyl Sulfate in the Cow
S. Zolhavarieh 1 , S. Zolhavarieh 2
1 Junior School of Veterinary Medicine, Bu-Ali Sina University,
Clinical Sciences, Hamedan, Iran
2 Hamadan University of Medical Sciences, Clinical Sciences,
Hamedan, Iran
Background: The spinal delivery of the cholinesterase inhibitor
neostigmine yields analgesia in rats and augments the analgesic