Oral and Poster Abstracts

635 Prevalence of the Pulmonary Lesions of the Bovines of the
Area of Tiaret
B. Mabrouk, T. Madjid, M. Toufik, M. Bakir
Batna University, Department of Veterinary Sciences, Batna Algeria,
Algeria
The seizures partial or total of the carcasses or the bodies by the veterinary
services constitute a true fear for the butchers. A study undertaken in the
slaughter-houses of the wilaya of Tiaret (Western Algeria) during the last
two years and a great incidence of respiratory lesions at the bovines was
found. This study shows the prevalence and the frequency of a series of
lesions raised on the lungs of 870 bovine autopsiés during medical
inspections and 744 pathologies were diagnosed. The seasonal
distribution of the lesions made it possible to put forward the effect of the
season on the appearance of the lesions. The cyst hydatic constitutes
pathology the most met (n=330 either 42.64%) followed 111 cases of
emphysema (or 14.35%) and 61 cases of congestion (or 7.89%). The
histopathologic study of the fragments of injured lungs taken at the
slaughter-house highlighted tissue deteriorations. According to the
localization of the lesions, one noted that the right lung is touched the most
for 92.60% of the cases that the left lung as well as the craniaux lobes for
87.05% comprativement with the caudal lobes of the lungs.
Key words: pulmonary lesions, histopathology, bovine
636 A Retrospective Study of Bovine Tuberculosis Eradication
Project and Human Tuberculosis
M. Sakha 1 , N. Ezatpanah 2 , A. Rohitoorbati 3
1 Islamic Azad University, Science & Research Branch, Internal
Medicine, Tehran, Iran
2 National Research Center, Internal Medicine, Kerman, Iran
3 Faculty of Veterinary, Internal Medicine, Kerman, Iran
Introduction: Tuberculosis (TB) is a chronic and zoonotic disease,
had known for many years. The cause of the disease is acid-fast bacillus
of mycobacteriacea, mycobacterium tuberculosis. Weakness,
emaciation and chronic respiratory symptoms are common signs of the
disease. The main group of human TB is pulmonary TB and the other
is extra pulmonary TB. It seems that many cases of extra pulmonary
TB are related to animal tuberculosis. This is a retrospective study
made during the last ten years (1991- 2000) on the incidence of human
and bovine TB and evaluated the bovine TB control project to human
TB incidence in city of Kerman, IRAN. Bovine TB control project is a
national project that has performed for many years in IRAN.
Materials and Methods: All data were taken from the veterinary
office in Kerman for bovine TB control project and the only centre of
human tuberculosis control for human cases. Data were analyzed and
variables of age, gender, root of infection and social situation were
considered in human section. The bovine positive cases have been
omitted and sent to the slaughter house before.
Results and Conclusion: This study showed that the most patients
were over 60 years old and then 21 to 30 years old. Women showed
more incidence of the disease. The prevalence of the extra pulmonary
TB in the first year of the study was11.9 in 100,000 and two years later
was relatively higher than. In remaining years the prevalence showed a
decreasing slope and reached to half of early year. Among the 219375
cows tested for TB in ten years,`65 cows were reactor. The most
incidence was found in the first and second years, that is, 37 and 18
cases, respectively. In later years, there was obviously a decreasing
slope with only one or two reactors in 1993 to 1998 and no cases in
1999 and 2000.There is positive relation between decrease in human
TB (extra pulmonary TB ) and the control of bovine TB in Kerman, so
that with the obvious decreasing of bovine reactors in last year of this
study, human cases also had a decreasing slope, although the human
extra pulmonary TB is nearly one third of total human cases and it
needs supplemental projects to control of human tuberculosis.
Key words: tuberculosis, bovine, human, retrospective
637 Bovine Theileriosis: Evaluation of 372 Cases during Spring
and Summer in South of Iran
M. Sakha 1 , M. Radfar 2 , M. Janbaz 3
1 Islamic Azad University, Science & Research Branch, Internal
Medicine, Tehran, Iran
2 Faculty of Veterinary Medicine, Parasitology, Kerman, Iran
3 Faculty of Veterinary Medicine, Internal Medicine, Kerman, Iran
84 XXV. Jubilee World Buiatrics Congress 2008
Bovine theileriosis caused by Theileria annulata is a dangerous and
important disease in tropical and subtropical areas. There are large
economical losses in these areas every year including Iran. The vector
of the disease in Iran, the tick of Hyalomma is found in the most parts
of the country. The disease is more seen in spring and summer. In this
study, the prevalence of the disease in terms of month of the year, age,
sex and animal breed were studied. Results showed that the maximum
and minimum prevalence of the disease was in May and June,
respectively, during the studied months. In relation to age, 76.2 percent
of the infected cattle were under a month old. In relation to the breed,
infection of different breeds of Holstein, crossbred and native cattle
were 1.6, 94.4 and 4.0 percent, respectively. In relation to sex, 55.4%
of males and 44.6% of females were affected. From the aspect of
clinical signs, nearly all cattle showed anorexia and enlargement of
lymph nods. 58% of blood smears showed less than 10%
intraerythrocytic form of theileria in microscopic high power field,
38% showed more than 10 percent and the rest was uncertain to
diagnose. It is concluded that in spite of all the means of prevention and
vaccination, the disease has been known as the most important disease
in the region especially in the warm months of the year parallel to the
activity of hyalomma. The dominant affected breed was crossbred,
because the most of the referred animals was crossbreds. Calves were
the most affected in this study because most of our cases were calf and
cattle were more treated at the farms. The infected RBC were not
correlated to the severity of the disease.
638 New Approaches in the Prophylaxis of Prion Infections
V. Vlizlo, P. Verbitskii, C. Mayor, V. Stadnyk
Institute of Animal Biology UAAS, Scientific Center for Prion
Infections Study, Lviv, Ukraine
Objectives of study: In nowadays very much the attention is spared to
the problem of the treatment of prion infections. Most efforts are
concentrated on the search of preparations which would block
occurance or reduce the level of already present PrP SC . At the same
time, very little attention is spared to the problem of prophylaxis of the
prion infections. Although work in this direction is rather active, taking
into considiration a creation of transgenic cattle in which the gene of
Prnp is knocked-out. But still it is unknown, how exactly will react an
organism on absence of such important protein as PrP C . That is why we
consider, that more perspective direction is a search of preparations
which would reduce the level of PrP C , in the same time depriving PrP SC
of substrate for replication. These preparations can be applied in risky
herds, with suspicious or sick animals are founded, for the reduction of
risk of prion infections among the healthy individuals. That is why the
purpose of our work was a search of preparations which would reduce
the level of PrP C in the organs of the prion-replicating system of
laboratory animals.
Materials and Methods: Work was done on laboratory rats treated
with heparine and Petosan Polisulfate. After decapitation in the proper
organs were probed: general maintenance of PrP C , type of expression
of its izoforms, maintenance of zinc and copper, activity of
superoxidedismutase, evaluation of DNA damage, ELISA test of PrP C
interaction with pentosan polisulfate (PPS), determination of UVspectrums
of PrP C at interaction with PPS.
Results: It is set that heparine and PPS is able to reduce the level of
PrP C in the organs of the prion-replicating system; unlike heparine, it is
shown that PPS operates in far less concentrations and does not
influence on the state of the antioxidant system. It is also shown that
action of PPS on PrP C proportionally depends on the concentration of
preparation. In the case of heparine such dependence was not
discovered. It is set that both preparations do not influence on genomic
DNA, which is proved by the absence of doblestrain DNA breaks.
Conclusions: It is set an inhibiting action of PPS and heparine on PrP C
in vivo.
Key words: prion infections, cellular prion, pentosan polysulphate
639 Brucellosis Surveillance in Jordan, 2001-2006
B. Barqawi 1 , Z. Mashhadani 1 , B. Hijjawi 2
1 Central of Disease Control & Prevention-CDC, Field Epidemiology
Training Program-FETP, Amman - Jordan, Jordan
2 MOH, DCD, Amman - Jordan, Jordan
Background: Brucellosis is a zoonotic bacterial disease that often
infects livestock animals (sheep, goats, and cattle). Animals often shed