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Table 3.4.9 continued<br />

Author<br />

Year<br />

Reference<br />

Country<br />

Study design<br />

Setting<br />

Population<br />

Inclusion & exclusion criteria<br />

Prevalence<br />

Index test<br />

Reference test<br />

Number of patients<br />

Drop-out rate<br />

Rater<br />

Rater training<br />

Interobserver reliability<br />

Sensitivity<br />

Specificity<br />

Study quality<br />

Comments<br />

Marton et al<br />

1991<br />

[54]<br />

Canada<br />

Design<br />

Cross sectional<br />

Setting<br />

Clinical, child-psychiatric<br />

Population<br />

n=119 consecutively admitted<br />

adolescents to either an outpatient<br />

clinic (n=93) or to<br />

a psychiatric ward<br />

Inclusion criteria<br />

–<br />

Exclusion criteria<br />

Not described<br />

Index test<br />

BDI-I<br />

Reference test<br />

DICA<br />

Number of patients<br />

n=119 (57% girls)<br />

Drop-out rate<br />

Not reported<br />

Rater, index test<br />

Self rating<br />

Rater training, index test<br />

NA<br />

Rater, reference test<br />

Psychiatrists, psychologists<br />

and social workers, number<br />

not reported<br />

Rater training, reference test<br />

Not described<br />

Interobserver reliability<br />

Not reported<br />

Cut off score 11<br />

Sensitivity: 80%<br />

Specificity: 70%<br />

Cut off score 16<br />

Sensitivity: 68%<br />

Specificity: 81%<br />

Moderate<br />

Comments<br />

Sampling method<br />

Adequate, consecutively<br />

admitted adolescents<br />

were recruited<br />

Blinding<br />

Probably<br />

Handling of missing data<br />

Unclear<br />

Prevalence<br />

21% (25/119)<br />

Ambrosini et al<br />

1991<br />

[53]<br />

USA<br />

Design<br />

Cross sectional<br />

Setting<br />

Child psychiatric<br />

outpatient clinic<br />

Population<br />

n=122 consecutively<br />

admitted adolescents<br />

Inclusion criteria<br />

Referred to a child depression clinic<br />

Exclusion criteria<br />

Physically ill, mentally retarded,<br />

symptoms clearly suggestive of<br />

anorexia/bulimia nervosa or autism<br />

Index test<br />

BDI-I<br />

Reference test<br />

K-SADS<br />

Number of patients<br />

n=122 (57% girls)<br />

Mean age: 15.5 years<br />

(range 12.6 to 19.8)<br />

Drop-out rate<br />

Not reported<br />

Rater, index test<br />

Self report<br />

Rater training, index test<br />

NA<br />

Rater, reference test<br />

Not reported<br />

Rater training, reference test<br />

Not reported<br />

Interobserver reliability<br />

κ for rater agreement<br />

ranged from 0.72 to 0.92<br />

Cut off scores >11<br />

Sensitivity: 48%<br />

Specificity: 40%<br />

Cut off scores >16<br />

Sensitivity: 35%<br />

Specificity: 49%<br />

Moderate<br />

Comments<br />

Sampling method<br />

Adequate<br />

Blinding<br />

Unclear<br />

Handling of missing data<br />

Not reported<br />

Prevalence MDD<br />

45% (55/122)<br />

The table continues on the next page<br />

162 diagnostik och uppföljning av förstämningssyndrom<br />

KAPITEL 3 • Systematisk litteraturgenomgång<br />

163

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