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Table 3.5.32 Calgary Depression Scale for Schizophrenia (CDSS)<br />

for assessment of severity of depression with DSM-IV criteria or<br />

CGI-S as reference standard.<br />

Author<br />

Year<br />

Reference<br />

Country<br />

Study design<br />

Setting<br />

Population<br />

Inclusion & exclusion criteria<br />

Prevalence<br />

Index test<br />

Reference test<br />

Number of patients<br />

Drop-out rate<br />

Rater<br />

Rater training<br />

Interobserver reliability<br />

Correlation<br />

Study quality<br />

Comments<br />

Müller et al<br />

2006<br />

[135]<br />

Germany<br />

Design<br />

Cross sectional<br />

Setting<br />

Psychiatric clinic in Germany<br />

Population<br />

n=119 inpatients<br />

(38% females) with<br />

schizophrenia<br />

Mean age: 31.9 years<br />

(SD 10.7)<br />

Inclusion criteria<br />

Stabilized acute schizophrenia<br />

Prevalence (reference test)<br />

31% no depression<br />

19% mild depression<br />

31% moderate depression<br />

19% severe depression<br />

Index test<br />

CDSS<br />

Reference test<br />

Global 4-point depression<br />

severity rating (DEP-SEV)<br />

based on CGI-S ratings +<br />

DSM-IV criteria for MDD<br />

with modifications that<br />

severity was rated independently<br />

of psychotic<br />

features and a time frame<br />

of 1 week<br />

Number of patients<br />

n=119<br />

Drop-out rate<br />

Not reported<br />

Rater of index test<br />

5 experienced psychiatrists<br />

Training of index rater<br />

Continuous rater training<br />

Rater of reference test<br />

Same 5 experienced<br />

psychiatrists<br />

Training of reference test<br />

Continuous rater training<br />

Interobserver reliability<br />

ICC ≥0.87 for CDSS<br />

and DEP-SEV<br />

CDSS vs DEP-SEV<br />

r=0.80 (p

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