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Table 3.5.27 continued
Author
Year
Reference
Country
Study design
Setting
Population
Inclusion & exclusion criteria
Prevalence
Index test
Reference test
Number of patients
Drop-out rate
Rater
Rater training
Interobserver reliability
Sensitivity
Specificity
Study quality
Comments
Carta et al
2006
[111]
Italy
Design
Cross sectional
Setting
One psychiatric
clinic in Italy
Population
n=123 consecutive patients
seeking psychiatric care,
or psychiatric evaluation
before medical treatment,
or applying for certification
of mental status (gun,
driving license)
Index test
HCL-32
Cut off ≥14
Reference test
SCID-I
Number of patients
n=123 (83% female)
Mean age: 37.9 ±12.4 years
Drop-out rate
Not reported
Rater of reference test
Unclear number of physicians
in psychiatry
Rater training
SCID-I training, but not specified
Interobserver reliability
Not reported
BP
Sensitivity: 73%
Specificity: 69%
Moderate
Comments
Sampling method
Adequate
Blinding
Probable
Handling of missing data
Unclear
Prevalence
BP or schizoaffective:
21% (26/123)
Meyer et al
2010
[112]
Germany
Design
Cross sectional
Setting
Psychiatric clinics and
outpatient clinics across
Germany
Population
n=488 consecutive patients
Mean age: 39.22 years
(SD 13.37, range 17–76)
(62.7% females)
Index test
HCL-32
Cut off ≥14
Reference test
SCID-I
Number of patients
n=361
Drop-out rate
26%
Rater of reference test
Unclear number
of psychologists
and psychiatrists
Rater training of reference test
Trained, but not specified
Interobserver reliability
Reported only for 1/7 centres;
BPI κ 0.95
BPII κ 0.89
Anxiety disorders κ 0.95
BP
Sensitivity: 88%
Specificity: 36%
Moderate
Comments
Sampling method
Adequate
Blinding
Yes
Handling of missing data
Patients with missing data
were excluded from analysis
Prevalence
BP: 32% (116/361)
BP = Bipolar disorder; BPI/II = Bipolar type I/II; DSM-IV = Diagnostic and statistical
manual of mental disorder, fourth edition; HCL-32 = Hypomania/mania symtom checklist;
MDD = Major depressive disorder; SCID-I = Structured clinical interview for DSM-IV
axis I disorders; SD = Standard deviation
392 diagnostik och uppföljning av förstämningssyndrom
KAPITEL 3 • Systematisk litteraturgenomgång
393