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Table 3.5.39 continued
Author
Year
Ref number
Country
Study design
Setting
Population
Inclusion & exclusion criteria
Prevalence
Index test
Reference test
Number of patients
Drop-out rate
Rater
Rater training
Interobserver reliability
Outcome measure
Main findings
(Correlations, p-value)
Study quality
Comments
Rush et al
2006
[171]
USA
Design
Cross sectional
Setting
18 primary and 23 speciality
care settings participating
in the STAR*D clinical trial
Population
n=1 500 consecutive outpatients
with non-psychotic
major depressive disorder
Inclusion criteria
Age 18–75 years
Index test
QIDS-16-SR
Reference test
QIDS-16-C
Number of patients
Exit: n=582
(63.1% females)
Mean age:
42.6±13.1 years
Drop-out rate
Not reported
Rater
Clinical research coordinators
independent from
clinicians without knowledge
of treatment
Rater training
Research outcome assessors
trained and certified
Outcome measure
Pearson correlations between
self vs clinician ratings
Pearson r: 0.89
Moderate
Structured interview
before instrument
QIDS-sr at clinic
visit, all three QIDS
measures within
2 days or less
Exclusion criteria
Patient with psychotic
and compulsive disorders,
bulimia nervosa, intolerance
to protocol treatment and
medical conditions such as
seizures
Test situation, period
between performance
Tests at baseline or after
first treatment step
Tests at same time, clinical
rating by blinded assessors
by telephone before collection
of clinician and self
rating tests
CI = Confidence interval; ICC = Intraclass correlation; IDS-C = Inventory of depressive
symptomatology, clinician rated; IDS-SR = Inventory of depressive symptomatology,
self report; MDD = Major depressive disorder; QIDS = Quick inventory of depressive
symptomatology
434 diagnostik och uppföljning av förstämningssyndrom
KAPITEL 3 • Systematisk litteraturgenomgång
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