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Table 3.5.21 continued<br />

Author<br />

Year<br />

Reference<br />

Country<br />

Study design<br />

Setting<br />

Population<br />

Inclusion & exclusion criteria<br />

Prevalence<br />

Index test<br />

Reference test<br />

Number of patients<br />

Drop-out rate<br />

Rater<br />

Rater training<br />

Interobserver reliability<br />

Sensitivity<br />

Specificity<br />

Study quality<br />

Comments<br />

Breslau et al<br />

1985<br />

[50]<br />

USA<br />

Design<br />

Cross sectional<br />

Setting<br />

4 pediatric specialties<br />

clinics in Cleveland, Ohio<br />

Population<br />

n=332 mothers to children<br />

and adolescents with disabilities<br />

(CF, CP, myelodysplasia or<br />

multiple handicaps)<br />

Prevalence MDD<br />

5.2%<br />

Index test<br />

CES-D, self-administered<br />

during interview<br />

Reference test<br />

DIS<br />

Number of participants<br />

n=319 came to interview<br />

complete data from 308<br />

Mean age: 42 years<br />

Drop-out rate<br />

3.4%<br />

Rater<br />

Lay female interviewers<br />

Rater training<br />

“Trained”<br />

Inter observer reliability<br />

κ 0.75 (6 months retest,<br />

personal vs telephone)<br />

Major depressive<br />

disorder<br />

Sensitivity: 87.5%<br />

Specificity: 73%<br />

Moderate<br />

Comments<br />

Sampling method<br />

Adequate<br />

Blinding<br />

Not reported<br />

Handling of missing data<br />

Not reported<br />

CES-D = Center for epidemiologic studies depression scale; CI = Confidence inerval;<br />

DIS = Diagnostic interview schedule; MDD = Major depressive disorder; NP = Neurological<br />

disorder; OP = Orthopedic disorder; SCID-I = Structured clinical interview for<br />

DSM-IV axis I disorders<br />

320 diagnostik och uppföljning av förstämningssyndrom<br />

KAPITEL 3 • Systematisk litteraturgenomgång<br />

321

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