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Table 3.6.6 GDS-30 for screening of depression with semistructured
or structured interview as reference standard.
Author
Year
Reference
Country
Study design
Setting
Population
Inclusion & exclusion criteria
Prevalence
Index test
Reference test
Number of patients
Drop-out rate
Rater
Rater training
Interobserver reliability
Outcome measure
Sensitivity
Specificity
Study quality
Comments
Vargas et al
2007
[22]
Brazil
Design
Cross sectional
Setting
General non-psychiatric
outpatient clinics
Population
Non-randomised sample,
predominantly women
Mean age: 70 years (range 60–96)
Caucasians: 78%
Inclusion criteria
Age: ≥60 years
Exclusion criteria
MMSE >13 for illiterate,
≥18 for low to mediumlevel
education, ≥26 for
high educational level
Index test
GDS-30, orally
Reference test
SCID-CV
Number of patients
n=484
Drop-out rate
Not reported
Rater of index test
5 trained interviewers
Training of index rater
Eight hour program,
conducted by a pedagogue
Rater of reference test
Psychiatrist
Training of reference test
Trained in the use of SCID-SV
Interobserver reliability
Not specified
Sensitivity: 87%
(95% CI, 81.3; 91.0)
Specificity: 73%
(95% CI, 66.9; 77.8)
Moderate
Comments
Blinding
Adequate
Handling of missing data
Not reported
Other comments
Cut off point = 12
Index and reference test
were completed within
one day (personal communication
with authors)
Prevalence MDD
43% (210/484)
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KAPITEL 3 • Systematisk litteraturgenomgång
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