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Table 3.4.13 P-GBI as screening instrument for mania with structured<br />

or semistructured interviews as reference standard.<br />

Author<br />

Year<br />

Reference<br />

Country<br />

Study design<br />

Setting<br />

Population<br />

Inclusion & exclusion criteria<br />

Prevalence<br />

Index test<br />

Reference test<br />

Number of patients<br />

Drop-out rate<br />

Rater<br />

Rater training<br />

Interobserver reliability<br />

Sensitivity<br />

Specificity<br />

Study quality<br />

Comments<br />

Youngstrom et al<br />

2008<br />

[95]<br />

USA<br />

Design<br />

Cross sectional<br />

Setting<br />

Outpatient psychiatric<br />

research clinic<br />

Population<br />

n=637 consecutive outpatients<br />

presenting for treatment<br />

Exclusion criteria<br />

Psychiatric disorder<br />

due to medical condition,<br />

pervasive developmental<br />

disorder, mental retardation<br />

Prevalence BPSD<br />

46% (294/637)<br />

Index test<br />

P-GBI<br />

Reference test<br />

K-SADS<br />

Number of patients<br />

n=637 (39% girls)<br />

Mean age: 11.3 years<br />

(SD 3.3)<br />

Drop-out rate<br />

Not reported<br />

Rater of index test<br />

Parents<br />

Rater training, index test<br />

NA<br />

Rater of reference test<br />

Child and adolescents<br />

psychiatrist, 17 research<br />

assistants (bachelor or<br />

master level)<br />

Rater training, reference test<br />

Highly trained.<br />

Every 10th interview<br />

was done by 2 raters<br />

Interobserver reliability<br />

Overall κ >0.85<br />

28 item ROC-AUC<br />

0.83<br />

10 item ROC-AUC<br />

0.86<br />

Moderate<br />

Comments<br />

Sampling method<br />

Adequate<br />

Blinding<br />

Satisfactory<br />

Handling of missing data<br />

72% of all parents<br />

answered all the<br />

P-GBI items.<br />

98% of the items<br />

were complete.<br />

Drop-out analyses<br />

provided<br />

The table continues on the next page<br />

176 diagnostik och uppföljning av förstämningssyndrom<br />

KAPITEL 3 • Systematisk litteraturgenomgång<br />

177

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