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Table 3.6.7 continued<br />

Author<br />

Year<br />

Reference<br />

Country<br />

Study design<br />

Setting<br />

Population<br />

Inclusion & exclusion criteria<br />

Prevalence<br />

Index test<br />

Reference test<br />

Number of patients<br />

Drop-out rate<br />

Rater<br />

Rater training<br />

Interobserver reliability<br />

Outcome measure<br />

Sensitivity<br />

Specificity<br />

Study quality<br />

Comments<br />

Phelan et al<br />

2010<br />

[30]<br />

USA<br />

Design<br />

Cross sectional<br />

Setting<br />

Two primary care clinics<br />

affiliated with a university<br />

Population<br />

n=502 consecutively<br />

recruited persons<br />

(62% females)<br />

n=227 fulfilled inclusion criteria<br />

Mean age: 78±7 years<br />

Comorbidity: 2 chronic<br />

medical conditions on average<br />

Index test<br />

GDS-15<br />

Reference test<br />

SCID-I (DSM-IV)<br />

Number of patients<br />

n=71<br />

Drop-out rate<br />

2/71<br />

Rater of index test<br />

“Administered by<br />

a research assistant”<br />

Rater of reference test<br />

A geriatric psychiatrist<br />

or gerontologic psychiatric<br />

nurse practitioner<br />

Rater training<br />

No more information<br />

than “trained in SCID<br />

administration”<br />

Interobserver reliability<br />

Not specified<br />

Minor and major<br />

depression at cut off ≥5<br />

Sensitivity: 88%<br />

(95% CI, 71; 96)<br />

Specificity: 14%<br />

(95% CI, 8; 16)<br />

Moderate<br />

Comments<br />

Sampling method<br />

Adequate but only 1/3 of<br />

eligible persons consented<br />

Blinding<br />

Adequate<br />

Handling of missing data<br />

Not reported<br />

Inclusion criteria<br />

Age: ≥65<br />

Exclusion criteria<br />

Severe dementia, unstable<br />

medical conditions, not fluent<br />

in English<br />

Prevalence<br />

MDD: 12%<br />

Minor depression: 13%<br />

The table continues on the next page<br />

488 diagnostik och uppföljning av förstämningssyndrom<br />

KAPITEL 3 • Systematisk litteraturgenomgång<br />

489

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