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Table 3.5.28 continued<br />

Author<br />

Year<br />

Reference<br />

Country<br />

Study design<br />

Setting<br />

Population<br />

Inclusion & exclusion criteria<br />

Prevalence<br />

Index test<br />

Reference test<br />

Number of patients<br />

Drop-out rate<br />

Rater<br />

Rater training<br />

Interobserver reliability<br />

Sensitivity<br />

Specificity<br />

Study quality<br />

Comments<br />

Weber Rouget<br />

et al<br />

2005<br />

[128]<br />

Switzerland<br />

Design<br />

Cross sectional<br />

and longitudinal<br />

Setting<br />

Outpatient psychiatric<br />

clinic in Switzerland<br />

Population<br />

n=96<br />

Mean age: 45 years<br />

(SD 9.8, range 18–63)<br />

Inclusion criteria<br />

Patients with mood disorders<br />

Index test<br />

MDQ<br />

Standard criteria<br />

Reference test<br />

SCID-I<br />

Number of patients<br />

96 (60% females)<br />

Drop-out rate<br />

Not reported<br />

Rater of reference test<br />

one psychiatrist and<br />

one psychologist<br />

Rater training<br />

Trained, but not<br />

described how<br />

Interobserver reliability<br />

Not reported<br />

BP<br />

Sensitivity: 74.1%<br />

Specificity: 90.5%<br />

Moderate<br />

Comments<br />

Sampling method<br />

Yes, but from specialized<br />

mood disorder clinic and<br />

selection criteria not<br />

clearly described<br />

Blinding<br />

Yes<br />

Handling of missing data<br />

Unclear<br />

Prevalence<br />

BP: 56.3% (54/96)<br />

Zimmerman et al<br />

2011<br />

[116]<br />

USA<br />

Design<br />

Cross sectional<br />

Setting<br />

Community-based outpatient<br />

practice affiliated with academic<br />

center; The Rhode Island MIDAS<br />

project<br />

Population<br />

n=773 consecutive outpatients<br />

Prevalence<br />

Lifetime BP: 10.6% (80/752)<br />

Index test<br />

MDQ<br />

Standard criteria<br />

Reference test<br />

SCID-I<br />

Number of patients<br />

752 (59.3% females)<br />

Mean age: 39.4 years<br />

(SD 13.9)<br />

Drop-out rate<br />

3%, 21 with<br />

incomplete MDQ<br />

Rater of reference test<br />

PhD level psychologists<br />

and research assistants<br />

Rater training<br />

Highly trained, monitored<br />

throughout project<br />

Interobserver reliability<br />

Reliability diagnosing BP<br />

κ 0.75<br />

BP<br />

Sensitivity: 67.5%<br />

Specificity: 84.5%<br />

High<br />

Comments<br />

Sampling method<br />

Adequate<br />

Blinding<br />

Yes<br />

Handling of missing data<br />

Patients with incomplete<br />

data not included in analysis,<br />

number reported<br />

and drop-out analysis<br />

BP = Bipolar disorder; BPI/II = Bipolar type I/II; CAPS = Clinical administered post-traumatic<br />

stress disorder scale; CI = Confidence interval; MDD = Major depressive disorder;<br />

MDQ = Mood disorder questionnaire; MINI = Mini international neuropsychiatric interview;<br />

SCID-I = Structured clinical interview for DSM-IV axis I disorders; UP = Unipolar;<br />

SD = Standard deviation<br />

402 diagnostik och uppföljning av förstämningssyndrom<br />

KAPITEL 3 • Systematisk litteraturgenomgång<br />

403

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