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Table 3.5.19 continued<br />

Author<br />

Year<br />

Reference<br />

Country<br />

Study design<br />

Setting<br />

Population<br />

Inclusion & exclusion criteria<br />

Prevalence<br />

Index test<br />

Reference test<br />

Number of patients<br />

Drop-out rate<br />

Rater<br />

Rater training<br />

Interobserver reliability<br />

Sensitivity<br />

Specificity<br />

Study quality<br />

Comments<br />

Loerch et al<br />

2000<br />

[28]<br />

Germany<br />

Design<br />

Cross sectional<br />

Setting<br />

Primary care and psychiatric<br />

clinics in Germany<br />

Population<br />

Medical and psychiatric outand<br />

inpatients. Patients were<br />

contacted by their physicians<br />

and invited to participate<br />

n=924<br />

Inclusion criteria<br />

Not reported<br />

Exclusion criteria<br />

Not reported<br />

Index test<br />

PRIME-MD<br />

Reference test<br />

Munich CIDI (M-CIDI)<br />

Number of patients<br />

n=704 (62% females)<br />

were administered<br />

both interviews<br />

Mean age: 46.1 years<br />

(SD 16.9)<br />

Drop-out rate<br />

Not reported<br />

Rater of index test<br />

Physicians<br />

Training of index rater<br />

No training<br />

Rater of reference test<br />

10 full-time research psychologists<br />

and 4 medical students<br />

with at least 4 years of medical<br />

school<br />

Training of reference test<br />

All were trained and supervised<br />

by 2 trained CIDI-raters<br />

Interobserver reliability<br />

Not reported<br />

Any mood disorder<br />

Sensitivity: 69%<br />

Specificity: 85%<br />

Major depressive disorder<br />

Sensitivity: 68%<br />

Specificity: 84%<br />

Moderate<br />

Comments<br />

Sampling method<br />

Mainly convenience<br />

sample. Number of<br />

patients contacted<br />

by physicians were<br />

not reported<br />

Blinding<br />

Yes<br />

Handling of missing data<br />

Not reported<br />

Prevalence<br />

Any mood disorder: 19.9% (140/704)<br />

MDD: 12.6% (89/704)<br />

APA = American journal of psychiatry; CI = Confidence interval; CIDI = Composite<br />

international diagnostic interview; DSM = Diagnostic and statistical Manual of mental<br />

disorder; MDD = Major depressive disorder; PRIME-MD = Primary health care evaluation<br />

of mental disorders; SCID-I = Structured clinical interview for DSM-IV axis I disorders;<br />

SD = Standard deviation<br />

310 diagnostik och uppföljning av förstämningssyndrom<br />

KAPITEL 3 • Systematisk litteraturgenomgång<br />

311

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