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Table 3.5.21 Sensitivity and specificity of CES-D with structured<br />

or semistructured interviews as reference standard.<br />

Author<br />

Year<br />

Reference<br />

Country<br />

Study design<br />

Setting<br />

Population<br />

Inclusion & exclusion criteria<br />

Prevalence<br />

Index test<br />

Reference test<br />

Number of patients<br />

Drop-out rate<br />

Rater<br />

Rater training<br />

Interobserver reliability<br />

Sensitivity<br />

Specificity<br />

Study quality<br />

Comments<br />

Caracciolo et al<br />

2002<br />

[49]<br />

Italy<br />

Design<br />

Cross sectional<br />

Setting<br />

Rehabilitation centre<br />

Population<br />

Consecutive patients<br />

with orthopedic (OP)<br />

and neurological (NP)<br />

disorders<br />

Inclusion criteria<br />

Ability to comply with CES-D<br />

and ≥17 on the Mini Mental<br />

State Examination (MMSE)<br />

Exclusion criteria<br />

Dementia, aphasia,<br />

severely ill<br />

Index test<br />

CES-D<br />

Reference test<br />

SCID-I<br />

Number of patients<br />

OP<br />

n=101 (68% females)<br />

Mean age: 70 years (61–77)<br />

NP<br />

n=50 (52% females)<br />

Mean age: 67 years (50–73)<br />

Drop-out rate<br />

Not reported<br />

Rater<br />

2 psychologists<br />

Rater training<br />

Certified psychologist<br />

Interobserver reliability<br />

Not reported<br />

OP<br />

Sensitivity: 100%<br />

Specificity: 57%<br />

(95% CI, 48; 67)<br />

NP<br />

Sensitivity: 100%<br />

Specificity: 36%<br />

(95% CI, 23; 49)<br />

Moderate<br />

Comments<br />

Sampling method<br />

Adequate<br />

Blinding<br />

Yes<br />

Handling of missing data<br />

Not reported<br />

Prevalence of MDD<br />

OP: 12%<br />

NP: 22%<br />

The table continues on the next page<br />

318 diagnostik och uppföljning av förstämningssyndrom<br />

KAPITEL 3 • Systematisk litteraturgenomgång<br />

319

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