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Table 3.5.22 continued<br />

Author<br />

Year<br />

Reference<br />

Country<br />

Study design<br />

Setting<br />

Population<br />

Inclusion & exclusion criteria<br />

Prevalence<br />

Index test<br />

Reference test<br />

Number of patients<br />

Drop-out rate<br />

Rater<br />

Rater training<br />

Interobserver reliability<br />

Sensitivity<br />

Specificity<br />

Study quality<br />

Comments<br />

Navarro et al<br />

2007<br />

[59]<br />

Spain<br />

Design<br />

Cross sectional<br />

Setting<br />

Clinical<br />

Population<br />

1 591 women consecutively<br />

visiting for routine postnatal<br />

follow up at 6 weeks after<br />

delivery.<br />

A stratified subsample<br />

of 428 women was drawn<br />

Index test<br />

EPDS<br />

Reference test<br />

SCID-I-NP<br />

Number of patients<br />

n=405<br />

Drop-out rate<br />

5% (23/428)<br />

Rater<br />

Two senior clinicians<br />

(one psychiatrist and<br />

one psychologist)<br />

Rater training<br />

Trained, and before<br />

initiation of the study<br />

they both assessed 40<br />

post partum women<br />

Interobserver reliability<br />

κ 0.80 for mood disorders<br />

MDD cut off 12/13<br />

Sensitivity: 66%<br />

Specificity: 96%<br />

High<br />

Comments<br />

Sampling method<br />

Adequate<br />

Blinding<br />

Yes<br />

Handling of missing data<br />

Unclear<br />

Exclusion criteria<br />

Illiterate women<br />

Dead newborn<br />

Prevalence MDD<br />

28% (115/405)<br />

CES-D = Center for epidemiologic studies depression scale for children; CI = Confidence<br />

interval; CIDI = Composite international diagnostic interview; CIDI-Auto = Composite<br />

international diagnostic interview, computer assisted version; CIDI-SF = Composite international<br />

diagnostic interview, short form; DIS = Diagnostic interview schedule; EDS =<br />

Edinburgh depression scale; EPDS = Edinburgh post natal depression scale; MDD = Major<br />

depressive disorder; MINI = Mini international neuropsychiatric interview; n = Number<br />

of patients; NA = Not applicable; PRIME-MD = The primary care evaluation of mental<br />

disorders; PSE = Present state examination; SADS = Schedule for affective disorders<br />

and schizophrenia; SADS-L = Schedule for affective disorders and schizophrenia, lifetime<br />

version; SCID-I = Structured clinical interview for DSM-IV axis I disorders; SCID-I-NP =<br />

Structured clinical interview for DSM-IV, non patient version; SD = Standard deviation;<br />

SPI = Standardized psychiatric interview<br />

352 diagnostik och uppföljning av förstämningssyndrom<br />

KAPITEL 3 • Systematisk litteraturgenomgång<br />

353

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