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Table 3.5.36 MAS for assessment of severity of bipolar disorder
with CGI-BP as reference standard.
Author
Year
Reference
Country
Study design
Setting
Populatio
Inclusion & exclusion criteria
Prevalence
Index test
Reference test
Number of patients
Drop-out rate
Rater
Rater training
Interobserver reliability
Outcome measure
Correlation
Study quality
Comments
Vieta et al
2008
[158]
Spain
Design
Cross sectional
Setting
18 psychiatric centers
across Spain
Population
n=215 consecutive
outpatients with BPI
or BPII on treatment
as usual
Inclusion criteria
BPI or BPII, stable patients
without restriction in scores,
unstable patients with
YMRS ≥18 and MADRS ≥22
Exclusion criteria
–
Prevalence
Not applicable
Index test
MAS
Reference test
CGI-BP
Number of patients
n=113 presenting
with manic episode
Mean age: 43.1 years
Drop-out rate
Not reported
Rater of index test
Clinicians
Training of index rater
Not reported
Rater of reference test
Same clinicians
Training of reference test
Not reported
Interobserver reliability
ICC (95% CI):
0.89 (0.80; 0.97)
(n=46)
Outcome measure
One-way ANOVAs of
MAS baseline scores
with CGI categories
as dependent variables
MAS vs CGI-BP
Adequate
Low
Comments
Sampling method
Adequate
Blinding
No
Handling of missing data
Not reported
Other comments
Neither correlation
coefficients or Intraclass
coefficients reported.
No post hoc (Eta2) analysis
of ANOVA statistics
BP = Bipolar disorder; CGI-BP = Clinical global impression for Bipolar disorder; ICC =
Intraclass correlation; MADRS = Montgomery-Åsberg depression rating scale; MAS =
Bech-Rafaelsen mania scale; SD = Standard deviation; YMRS = Young mania rating scale
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