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Table 3.5.29 Sensitivity and specificity of Mood Disorder Questionnaire (MDQ)<br />

with modified criteria with structured or semistructured interviews as reference<br />

standard.<br />

Author<br />

Year<br />

Reference<br />

Country<br />

Study design<br />

Setting<br />

Population<br />

Inclusion & exclusion criteria<br />

Prevalence<br />

Index test<br />

Reference test<br />

Number of patients<br />

Drop-out rate<br />

Rater<br />

Rater training<br />

Interobserver reliability<br />

Sensitivity<br />

Specificity<br />

Study quality<br />

Comments<br />

Gervasoni et al<br />

2009<br />

[117]<br />

Switzerland<br />

Design<br />

Cross sectional<br />

Setting<br />

General outpatient psychiatric<br />

clinic in Geneva, Switzerland<br />

Population<br />

n=183 patients with symptoms<br />

of mood disorder, newly referred<br />

for treatment<br />

Exclusion criteria<br />

Previously treated in specialized<br />

unit for mood disorders<br />

Index test<br />

MDQ with standard<br />

criteria or modified<br />

Geneva algorithm<br />

Reference test<br />

SCID-I<br />

Number of patients<br />

n=146 (53% females)<br />

Median age: 40 years<br />

(range 19–64)<br />

Drop-out rate<br />

20%<br />

Rater of reference test<br />

Psychiatrist or psychologist<br />

Rater training<br />

Well-trained, but not<br />

described how<br />

Interobserver reliability<br />

Not reported<br />

BP vs UP<br />

Standard criteria<br />

Sensitivity: 63.6%<br />

Specificity: 83.3%<br />

Geneva algorithm<br />

Sensitivity: 72.7%<br />

Specificity: 78.4%<br />

BP I vs UP<br />

Standard criteria<br />

Sensitivity: 85.0%<br />

Geneva algorithm<br />

Sensitivity: 90.0%<br />

Moderate<br />

Comments<br />

Sampling method<br />

Adequate<br />

Blinding<br />

Yes<br />

Handling of missing data<br />

Unclear<br />

Prevalence<br />

BP: 30% (44/146)<br />

BP II vs UP<br />

Standard criteria<br />

Sensitivity: 45.8%<br />

Geneva algorithm<br />

Sensitivity: 58.3%<br />

The table continues on the next page<br />

404 diagnostik och uppföljning av förstämningssyndrom<br />

KAPITEL 3 • Systematisk litteraturgenomgång<br />

405

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