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Table 3.6.9 continued<br />

Author<br />

Year<br />

Reference<br />

Country<br />

Study design<br />

Setting<br />

Population<br />

Inclusion & exclusion criteria<br />

Prevalence<br />

Index test<br />

Reference test<br />

Number of patients<br />

Drop-out rate<br />

Rater<br />

Rater training<br />

Interobserver reliability<br />

Outcome measure<br />

Sensitivity<br />

Specificity<br />

Study quality<br />

Comments<br />

Ayalon et al<br />

2010<br />

[39]<br />

Israel<br />

Design<br />

Cross sectional<br />

Setting<br />

Two health centers in Israel<br />

Population<br />

Recruitment from the waiting<br />

rooms by research assistants<br />

Inclusion criteria<br />

Older primary care patients<br />

Exclusion criteria<br />

Not specified<br />

Prevalence<br />

MDD and/or dysthymia: 3.9%<br />

Index test<br />

PHQ-9<br />

Reference test<br />

SCID 1 (DSM-IV)<br />

Number of patients<br />

n=153 (40.5% female)<br />

Mean age: 75 years<br />

(SD 8.1)<br />

Drop-out rate<br />

Not reported<br />

Rater of index test<br />

Self rating<br />

Training of index test rater<br />

Rater of reference test<br />

Two trained mental health<br />

graduate research assistants<br />

Training of reference test rater<br />

3 day training course<br />

Interobserver reliability<br />

Adequate interobserver<br />

reliability was established<br />

against an experienced<br />

clinical psychologist<br />

MDD and/or dysthymia<br />

Sensitivity: 67%<br />

Specificity: 99%<br />

Study quality<br />

Moderate<br />

Comments<br />

Sampling method<br />

Adequate<br />

Blinding<br />

Not satisfactory<br />

Handling of missing data<br />

Not reported<br />

Other comments<br />

Instruments were administered<br />

”on the same<br />

time” (personal communication<br />

with authors)<br />

CI = Confidence interval; DSM-IV = Diagnostic and statistical manual of mental disorders,<br />

fourth edition; MDD = Major depressive disorder; MMSE = Mini-mental scale examination;<br />

NA = Not applicable; PHQ-9 = Patient health questionnaire, nine items; SCID =<br />

Structured clinical interview for DSM-disorders; SD = Standard deviation<br />

502 diagnostik och uppföljning av förstämningssyndrom<br />

KAPITEL 3 • Systematisk litteraturgenomgång<br />

503

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