Fulltext - SBU

Table 3.6.7 GDS-15 for screening of depression with semistructured
or structured interview as reference standard.
Author
Year
Reference
Country
Study design
Setting
Population
Inclusion & exclusion criteria
Prevalence
Index test
Reference test
Number of patients
Drop-out rate
Rater
Rater training
Interobserver reliability
Outcome measure
Sensitivity
Specificity
Study quality
Comments
Davison et al
2009
[28]
Australia
Design
Cross sectional
Setting
Randomly selected Low level care
facilities, ”homes for the elderly”
in Melbourne
Population
n=282 eligible
Inclusion criteria
MMSE: ≥24/30
>65 years
Exclusion criteria
Psychotic disorder or intellectual
disability, inability to communicate
in English, severe hearing impairment
Prevalence MDD
16.1%
According to senior staff: 22.0%
Index test
GDS-15
Reference test
SCID-I elderly
SCID-I informant
Number of patients
n=177 (76.8% female)
Mean age: 84.7 years
(SD 6.15)
Drop-out rate
5.1%
Rater of index test
A research assistant
read the GDS-15 aloud
Training of index rater
Not reported
Rater of reference test
A clinical geropsychologist
interviewed the elderly
A psychologist interviewed
a senior staff member who
knew the participant well
Training of reference test
Not reported
Interobserver reliability
Overall concordance between
diagnostic procedures=94%,
κ 0.81 between the two reference
standards
MDD at cut off 5
Self rating
Sensitivity: 93%
(95% CI, 76; 99)
Specificity: 77%
(95% CI, 69; 84)
Informant rating
Sensitivity: 70%
(95% CI, 53; 84)
Specificity: 76%
(95% CI, 68; 83)
Moderate
Comments
Sampling method
Adequate
Blinding
Order of the interviews varied
randomly to avoid order bias
Handling of missing data
No missing data were reported
Other comments
Medium delay between
GDS-15 and SCID was
4.82 days SD 2.76 days
The table continues on the next page
484 diagnostik och uppföljning av förstämningssyndrom
KAPITEL 3 • Systematisk litteraturgenomgång
485