Program - Society of Toxicology

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44 th Annual Meeting and ToxExpo Program Description TUESDAY #932 3β-HYDROXY-5-OXO-5, 6-SECOCHOLESTAN-6- AL, A MAJOR OZONIZATION PRODUCT OF CHOLESTEROL, INDUCES APOPTOSIS IN CARDIOMYOCYTES. M. Haque 1 , I. Sehgal 1 , S. Murthy 2 , J. Francis 1 and R. Uppu 3 . 1 LSU School of Veterinary Medicine, Baton Rouge, LA, 2 Tulane University Health Sciences Center, New Orleans, LA and 3 Southern University, Baton Rouge, LA. #933 INCREASED SUSCEPTIBILITY OF HYPERTHYROID RATS TO OZONE: EARLY EVENTS AND MECHANISMS. L. Huffman 1,2 , C. Beighley 3 , D. Frazer 1,2 , W. McKinney 1 and D. Porter 1,2 . 1 2 PPRB, NIOSH, Morgantown, WV, Physiology and Pharmacology, West Virginia University, Morgantown, WV and 3 Biostatistics, NIOSH, Morgantown, WV. #934 INHIBITION OF TRANSFORMING GROWTH FACTOR BETA MNRA TRANSCRIPTION BY ANTISENSE OLIGONUCLEOTIDES IN AMIODARONE TREATED HAMSTERS. H. conway, U. doshi and J. M. cerreta. Department of Pharmaceutical Sciences, St. John’s University, Jamaica, NY. #935 INVESTIGATION OF PREVENTION OF AMIODARONE- AND DESETHYLAMIODARONE-INDUCED TOXICITY IN HUMAN PERIPHERAL LUNG EPITHELIAL CELLS HPL1A. A. C. Nicolescu, J. F. Brien, W. J. Racz and T. E. Massey. Pharmacology & Toxicology, Queen’s University, Kingston, ON, Canada. #936 GENE MICROARRAY ANALYSIS IN A RAT MODEL OF SMOKE INHALATION-INDUCED ACUTE LUNG INJURY. S. S. Wong 1 , N. N. Sun 1 , C. D. Fastje 1 , R. Lantz 2 and M. L. Witten 1 . 1 Center for Toxicology & Department of Pediatrics, The University of Arizona, Tucson, AZ and 2 Center for Toxicology & Department of Cell Biology/Anatomy, The University of Arizona, Tucson, AZ. #937 EXPRESSION AND CHARACTERIZATION OF TRPM8 RECEPTORS IN THE LUNG EPITHELIUM. A. S. Sabnis, M. E. Johansen, G. S. Yost and C. A. Reilly. Pharmacology & Toxicology, University of Utah, Salt Lake City, UT. #938 AEROSOLIZED HYALURONAN MODIFIES ENDOTOXIN-INDUCED LUNG INJURY IN A TIME-DEPENDENT MANNER. P. Nadkarni, G. Kulkarni and J. Cantor. Pharmacy and Allied Health Professions, St John’s University, New York. Sponsor: L. Trombetta. #939 IMMUNE RESPONSE TO ZYMOSAN-INDUCED PULMONARY INFLAMMATION IN RATS. S. Young, J. R. Roberts and J. M. Antonini. NIOSH, Morgantown, WV. #940 HYDROGEN SULFIDE EXPOSURE CAUSES INTRACELLULAR ACIDIFICATION OF RAT NASAL RESPIRATORY EPITHELIAL CELLS. E. S. Roberts, V. A. Wong, B. E. McManus and D. C. Dorman. CIIT Centers for Health Research, Research Triangle Park, NC. #941 PERTURBATION OF COPPER HOMEOSTASIS AND EXPRESSION OF COPPER-BINDING PROTEINS IN CADMIUM-RESISTANT LUNG FIBROBLASTS. D. K. Chou 1 , Y. Zhao 1 , S. Gao 1 , L. Chen 1 , I. Chou 2 , P. Toselli 1 , P. Stone 1 and W. Li 1 . 1 Biochemistry, Boston University School of Medicine, Boston, MA and 2 Microbiology, Boston University School of Medicine, Boston, MA. #942 PHOTOCHEMICAL REACTIONS ENHANCE INFLAMMATORY RESPONSES IN HUMAN LUNG CELLS. M. Doyle 1 , K. G. Sexton 1 , H. Jeffries 1 , K. Lichtveld 1 and I. Jaspers 2,1 . 1 ESE, UNC-CH, Chapel Hill, NC and 2 CEMALB, UNC-CH, Chapel Hill, NC. #943 INHALATION EXPOSURE TO TERTIARY AMYL METHYL ETHER (TAME) ALTERS THE ACTIVITIES OF CYTOCHROME P450 ISOZYMES IN HEPATIC AND RESPIRATORY TISSUES OF SPRAGUE DAWLEY RATS. J. L. Weissert and R. A. Schatz. Toxicology, Northeastern University, Boston, MA. #944 BIOPERSISTENCE OF ROCK WOOL (RW) IN THE RAT LUNG AFTER SHORT-TERM INHALATION VIA NOSE. Y. Kudo, Y. Sugiura, M. Tsunoda, T. Satoh and Y. Aizawa. Department of Preventive Medicine and Public Health, Kitasato University School of Medicine, Sagamihara, Japan. #945 TWO-WEEK INHALATION STUDIES WITH DISK-SHAPED PARTICLES OF POTASSIUM TITANATE COMPOUNDS: TERRACESS PS AND TERRACESS LS. S. Sakai 1 , K. Inada 1 , A. K. Tanaka 1 , D. P. Kelly 3 , G. Sykes 3 and K. P. Lee 4 . 1 Otsuka Chemical Co. Ltd., Osaka, Japan, 2 DuPont Haskell Laboratory, Newark, DE, 3 Veterinary Pathology Services, West Grove, PA and 4 Pathology Consulting, Newark, DE. #946 CHRONIC LUNG TOXICITY IN RATS DUE TO EXPOSURE TO DIFFERENT CONCENTRATIONS OF THE MINERAL OIL. F. S. Abouzakhar 1,2,3 . 1 Electrical Eng., Al-Tahadi University, Sirt, Libya, 2 Forensic Med.& Toxicology, El Minia University, El Minia, Egypt, 3 Pharmacology & Therapeutics, Ain Shams University, Ain Shams, Egypt and 4 Internal Medicine, Al-Tahady University, Sirt, Libya. Sponsor: F. Abouzakhar. #947 SENSORY IRRITATION RESPONSE TO ATP, α, β- METHYLENE-ATP AND ADENOSINE AEROSOLS. W. S. Wilkie and J. B. Morris. Toxicology Program, University of Connecticut, Storrs, CT. 120 SOT’s 44 th Annual Meeting
44 th Annual Meeting and ToxExpo Program Description Tuesday Morning, March 8 9:30 AM to 12:30 PM Exhibit Hall POSTER SESSION: REPRODUCTION AND DEVELOPMENT Chairperson(s): Wendy Koch, Epona Associates LLC, Willington, CT and Eve Mylchreest, DuPont Haskell Laboratories, Newark, DE. Displayed: 9:30 AM–12:30 PM Attended: 11:00 AM–12:30 PM #948 EFFECTS OF GROUP HOUSING ON REPRODUCTIVE PARAMETERS IN THE SEXUALLY MATURE CYNOMOLGUS MONKEY. G. Weinbauer 1 , M. Niehoff 1 , M. Bergmann 2 and W. Mueller 1 . 1 Covance Laboratories GmbH, 48163 Muenster, Germany and 2 Institute of Veterinary Anatomy, University of Giessen, 35392 Giessen, Germany. #949 28-DAY INHALATION AND REPRODUCTIVE/DEVELOPMENTAL SCREENING TOXICITY STUDIES OF TETRAMETHYLSILANE IN SPRAGUE-DAWLEY RATS. W. Siddiqui 1 , L. Meeker 1 , J. Tobin 1 , J. Crissman 1 , J. Knochel 1 , S. Crofoot 1 , G. Burin 2 and K. Plotzke 1 . 1 Health and Environmental Sciences, Dow Corning Corporation, Midland, MI and 2 Toxicology Division, Technology Sciences Group, Washington, DC. #950 GLYCIDOXYPROPYLTRIMETHOXYSILANE (TMSPGE): ONE-GENERATION REPRODUCTION STUDY IN THE RAT. W. H. Koch 1 and H. Becker 2 . 1 Epona Associates, LLC, Willington, CT and 2 Toxicology/Safety Assessment 1, RCC Ltd., Fullinsdorf, Switzerland. #951 DEVELOPMENTAL TOXICITY AND COMBINED MALE AND FEMALE FERTILITY STUDIES IN RATS EXPOSED TO 2, 3-DICHLORO-1, 3- BUTADIENE (DCBD) BY INHALATION. L. A. Malley, E. Mylchreest, A. O. O’Neill, T. A. Kegelman, G. P. Sykes and R. Valentine. DuPont Haskell Laboratory, Newark, DE. #952 LACK OF FERTILITY OR ESTROUS CYCLE EFFECTS OF A FLUORINATED ORGANIC ETHOXYLATE SURFACTANT IN RATS. J. M. Lewis 1 , E. Mylchreest 1 , S. R. Frame 1 , R. C. Buck 2 and J. C. Stadler 1 . 1 DuPont Haskell Laboratory, Newark, DE and 2 DuPont, Wilmington, DE. #953 DEVELOPMENTAL IMMUNOTOXICITY OF DEXAMETHASONE AND CYCLOSPORIN A. I. D. Waalkens-Berendsen, A. P. Wolterbeek, A. Dijkstra, F. C. Kuper, A. H. Penninks, M. Zijverden van, E. I. Klein Koerkamp, P. T. Berg van den and M. M. Tegelenbosch. Toxicology and Applied Pharmacology, TNO Nutrition and Food Research, Zeist, Netherlands. Sponsor: V. Feron. #954 BEHAVIORAL ABNORMALITY ASSOCIATED WITH ATTENTION DEFICIT HYPERACTIVE DISORDER IN RAT OFFSPRING PRENATALLY EXPOSED TO 5-BROMO-2’-DEOXYURIDINE. K. Orito 1 , M. Kuwagata 2 , T. Ogawa 3 , K. Muneoka 3 , M. Shirai 1 , F. Akahori 1 , K. Mishima 4 and M. Fujiwara 4 . 1 Pharmacology, Azabu university School of Veterinary Medicine, Sagamihara, Japan, 2 Hatano Research Institute, FDSC, Hadano, Japan, 3 Anatomy I, Showa University School of Medicine, Tokyo, Japan and 4 Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan. #955 MATERNAL DETOXICATION VIA CYP1A1 PREVENTS METABOLIC ACTIVATION AND EMBRYO TOXICITY FOLLOWING ORAL EXPOSURE TO BENZO(A)PYRENE. C. P. Curran 1 , M. L. Miller 1 , N. Dragin 1 , T. P. Dalton 1 , D. W. Nebert 1 and S. Uno 2 . 1 University of Cincinnati Medical Center, Cincinnati, OH and 2 Nihon University School of Medicine, Tokyo, Japan. #956 MATURATION OF HEPATIC CYTOCHROME P450 ISOZYMES IN DEVELOPING SPRAGUE- DAWLEY RATS. B. McPhail, S. Muralidhara, S. Anand and J. Bruckner. Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, GA. #957 RESISTANCE TO PCB INDUCTION OF P450 1A (CYP1A) ACTIVITY AND REACTIVE OXYGEN SPECIES (ROS) PRODUCTION IN A POLLUTED KILLIFISH (FUNDULUS HETEROCLITUS) POPULATIONS. X. Arzuaga 1 and A. A. Elskus 2 . 1 Toxicology, University of Kentucky, Lexington, KY and 2 Department of Biological Sciences, USGS, Orono, ME. Sponsor: B. Hennig. #958 SUB-CHRONIC SODIUM ARSENATE EXPOSURE AFFECTS FERTILITY AND EARLY DEVELOPMENT IN HOMING PIGEONS: A MODEL FOR MIGRATORY BIRDS. J. Brasel 1 , A. C. Collier 2 and C. A. Pritsos 2,1 . 1 Environmental Sciences and Health Program, University of Nevada, Reno, NV and 2 Nutrition, University of Nevada, Reno, NV. #959 TRUE HERMAPHRODITISM IN A CD-1 MOUSE. A. Moran. Covance Laboratories Ltd., Harrogate, United Kingdom. Sponsor: D. Everett. TUESDAY up-to-date information at www.toxicology.org 121
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Contents Program Overview .........
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Annual Meeting Events Calendar (Con
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Sheraton Hotel Map 44 th Annual Mee
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Itinerary Planner Computer Stations
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General Information 44 th Annual Me
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2005 Award Winners The Society of T
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INTERNATIONAL HARMONIZATION OF TECH
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Saturday Afternoon, March 5 2:00 PM
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SOT Affiliates for 2005 44 th Annua
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Program - Society of Toxicology

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