Program - Society of Toxicology

44 th Annual Meeting
and ToxExpo
ToxExpo
Exhibits & Informational Sessions (Continued)
Toxicity Testing: What Bone Marrow Can
Tell Us
Presented by StemCell Technologies, Inc.
Tuesday, March 8
9:45 AM–10:45 AM
Room 215
Over the past three decades, a spectrum of standardized assays
has been developed to characterize and measure bone marrow
function and assess the multiple cell lineages it contains. In
humans, bone marrow is one of the five major organ systems
most sensitive to chronic low-dose chemical toxicants, making it
an important target to assess in toxicity screening. This session
will illustrate the rationale for targeting bone marrow for drug
toxicity screening, assays that are employed and importance of
using primary human cells in functional cell-based assays.
Searching the NTP Databases
Presented by NIEHS
Tuesday, March 8
11:00 AM–12:00 NOON
Room 215
The National Toxicology Program (NTP) conducts studies on
potentially toxic agents to determine their impact on human
health. Enhancing public access to these data, this workshop
provides information about what is available within the NTP
databases, using real examples to demonstrate the search
process.
Designing Better Pre-Clinical Studies
Using Gene Expression Analysis
Presented by Gene Logic, Inc.
Tuesday, March 8
11:00 AM–12:00 NOON
Room 223
Understanding the expression pattern of a target protein in
various tissues can help you plan your small molecule and
biologics safety studies with more precision by suggesting
additional target tissues and potential areas for concern. In this
presentation, you will hear case studies on how scientists can use
Gene Logic’s web-based ASCENTA System to design better
pre-clinical studies.
Rapid Generation of Predictive
Toxicogenomic Analysis
Presented by Gene Logic, Inc.
Tuesday, March 8
12:15 PM–1:15 PM
Room 223
Learn how to facilitate drug candidate selection by characterizing
a compound’s toxicity profile using an easy, intuitive toxicogenomic-based
software application. Several case studies will be
discussed that demonstrate how these rapidly generated results
can be combined with other data to help make better inform
compound decisions.
Leveraging a Multi-Dimensional
Cardiovascular Assessment During Lead
Optimization
Presented by CorDynamics
Tuesday, March 8
1:30 PM–2:30 PM
Room 215
CorDynamics is a contract research organization focused on
examining the cardiac effects of emerging drug candidates. Our
models allow us to optimize these lead candidates early in the
drug development process. Focusing on this critical and dynamic
phase improves the attrition rates of compounds selected for
further testing, thereby reducing the overall costs and timelines
associated with your projects.
An Introduction to Microarrays
and GeneChip® Technology for
Toxicogenomics
Presented by Affymetrix
Tuesday, March 8
2:45 PM–3:45 PM
Room 215
The Affymetrix GeneChip® System enables toxicologists to reliably
generate, analyze, and manage large quantities of genetic
information for accelerated research and biomarker discovery.
This course is an introduction to GeneChip microarray design,
performance, and analysis for applications in toxicogenomics.
up-to-date information at www.toxicology.org 17