Program - Society of Toxicology

44 th Annual Meeting
and ToxExpo
Program Description
#1359 9:10 DRE BINDING IS NOT REQUIRED FOR
REPRESSION OF AHR SIGNALING BY AHRR. B.
R. Evans 1,2 , L. L. Allan 3,4 , D. H. Sherr 3 and M. E.
Hahn 1 . 1 Biology, Woods Hole Oceanographic
Institution, Woods Hole, MA, 2 Biology, Boston
University, Boston, MA, 3 Environmental Health, Boston
University School of Public Health, Boston, MA and
4 Microbiology, Boston University School of Medicine,
Boston, MA.
#1360 9:30 ERK KINASE ACTIVITY CONTRIBUTES TO AH
RECEPTOR TARGETED PROTEIN
DEGRADATION AND TRANSCRIPTIONAL
POTENTIAL. S. CHEN and R. H. Tukey. Laboratory
of Environmental Toxicology, Departments of
Chemistry & Biochemistry and Pharmacology,
University of California, San Diego, La Jolla, CA.
#1361 9:50 INVOLVEMENT OF KINASE SIGNALING
PATHWAYS IN AH-RECEPTOR MEDIATED
GENE EXPRESSION IN RAT LIVER CELLS. B. V.
Madhukar 1 , G. Chen 1 , C. Sorrentino 2 and M. S.
Denison 2 . 1 Pediatrics/Human Development, Michigan
State University, East Lansing, MI and 2 Environmental
Toxicology, University of California at Davis, Davis,
CA.
#1362 10:10 ACTIVATION OF THE ARYL HYDROCARBON
RECEPTOR ALTERS IN VIVO HEPATOCYTE
PROLIFERATION. K. A. Mitchell 1 , S. A. Hattenbach 2
and C. J. Elferink 1 . 1 Department of Pharmacology and
Toxicology, University of Texas Medical Branch,
Galveston, TX and 2 UTMB Summer Undergraduate
Research Program, University of Houston-Downtown,
Houston, TX.
#1363 10:30 TEMPORAL AND DOSE-DEPENDENT HEPATIC
GENE EXPRESSION PATTERNS IN MICE
PROVIDE NEW INSIGHTS INTO TCDD-
MEDIATED HEPATOTOXICITY. D. R. Boverhof, L.
D. Burgoon, C. Tashiro, B. Chittim, J. R. Harkema and
T. R. Zacharewski. Biochemistry & Molecular Biology,
National Food Safety & Toxicology Center, and Center
for Integrative Toxicology, Michigan State University,
East Lansing, MI.
#1364 10:50 EXPRESSION OF DOMINANT NEGATIVE N-
CADHERIN RESULTS IN AHR-DEPENDENT
GENE INDUCTION IN HEPA 1C1C7 WILD-TYPE
CELLS. L. M. Van Pay 1 and B. Allen-Hoffmann 1,2 .
1 Molecular and Environmental Toxicology, University
of Wisconsin, Madison, WI and 2 Pathology and
Laboratory Medicine, University of Wisconsin,
Madison, WI.
#1365 11:10 ERα IS A LIGAND-DEPENDENT MODULATOR
OF AHR TRANSCRIPTION: INTERPLAY
BETWEEN THE TWO RECEPTOR SYSTEMS. J.
Matthews, B. Whilen and J. Gustafsson. Department of
Biosciences, Karolinska Institute, Huddinge, Sweden.
Wednesday Morning, March 9
8:30 AM to 11:30 AM
Room RO1
PLATFORM SESSION: FEMALE AND MALE REPRODUCTIVE
SYSTEMS
Chairperson(s): Kimberly Miller, University of Maryland, Baltimore, MD and
Wendy Jefferson, NIEHS, Research Triangle Park, NC.
#1366 8:30 THERAPEUTIC CONCENTRATIONS OF
HALOPERIDOL DO NOT DIRECTLY AFFECT
OVARIAN FUNCTION AND OOCYTE QUALITY
AS TESTED IN MOUSE OVARIAN FOLLICLE
CULTURE MODEL. R. Cortvrindt 1,2 , E. Gobbers 1 , V.
Van Merris 1 and J. Smitz 1 . 1 EggCentris NV, Zellik,
Belgium and 2 Follicle Biology Laboratory, Vrije
Universiteit Brussel, Brussels, Belgium. Sponsor: G.
Daston.
#1367 8:50 BCL-2 FAMILY MEMBERS PROTECT AGAINST
METHOXYCHLOR-INDUCED TOXICITY OF
MOUSE OVARIAN ANTRAL FOLLICLES IN
VITRO. K. P. Miller 1 , C. Greenfeld 2 and J. A. Flaws 1 .
1 Program in Toxicology, University of Maryland-School
of Medicine, Baltimore, MD and 2 Department of
Physiology, University of Maryland-School of
Medicine, Baltimore, MD.
#1368 9:10 REVERSAL OF BENZO-A-PYRENE EFFECTS
ON OXYTOCIN-INDUCED CA 2+
OSCILLATIONS IN HUMAN MYOMETRIAL
PHM1-41 CELLS. R. Barhoumi, I. Awooda, S. Safe
and R. C. Burghardt. Faculty of Toxicology, Texas
A&M University, College Station, TX.
#1369 9:30 EFFECTS OF ATRAZINE AND AN ATRAZINE
METABOLITE MIXTURE ON DIFFERENTIATED
MAMMARY EPITHELIAL CELL MILK
PROTEIN PRODUCTION IN CULTURE. E. P.
Hines, R. Barbee, M. Blanton, M. S. Pooler and S. E.
Fenton. Reproductive Toxicology Division, U.S. EPA,
ORD, NHEERL, Research Triangle Park, NC.
#1370 9:50 NEONATAL EXPOSURE TO THE
PHYTOESTROGEN GENISTEIN ALTERS
REPRODUCTION IN FEMALE CD-1 MICE. W.
Jefferson 1,2 , E. Padilla-Bank 1 and R. Newbold 1 .
1 Laboratory of Molecular Toxicology, NIEHS,
NIH/DHHS, Research Triangle Park, NC and
2 Molecular and Environmental Toxicology Department,
North Carolina State University, Raleigh, NC.
#1371 10:10 ESTROGEN-INDUCED PATTERN OF GENE
EXPRESSION AT HIGH AND LOW DOSES IN
FETAL MALE RAT TESTIS. J. M. Naciff, K. M.
Hess, J. E. Maritnez, G. J. Overmann, L. M. Foertsch,
S. M. Torontali, G. J. Carr, J. P. Tiesman and G. P.
Daston. Procter & Gamble Company, Cincinnati, OH.
#1372 10:30 LOW DOSE CELLULAR RESPONSES IN THE
FETAL RAT TESTIS IN UTERO EXPOSED TO DI
(N-BUTYL) PHTHALATE. E. Kleymenova, C.
Swanson and K. W. Gaido. CIIT CHR, Research
Triangle Park, NC.
WEDNESDAY
up-to-date information at www.toxicology.org 155