Program - Society of Toxicology

44 th Annual Meeting
and ToxExpo
Program Description
MONDAY
Monday Afternoon, March 7
1:30 PM to 4:30 PM
Exhibit Hall
POSTER SESSION: RISK ASSESSMENT I
Chairperson(s): Moiz Mumtaz, ATSDR, Chamblee, GA.
Displayed: 1:30 PM–4:30 PM
Attended: 1:30 PM–3:00 PM
#370 CONCEPTUAL PRINCIPLES FOR UTILIZING
OMIC TECHNOLOGIES IN MECHANISTIC
RISK ASSESSMENT. C. Borgert 1,2 , P. Guiney 3 , G.
Casella 4 and K. Shiverick 5 . 1 Applied Pharmacology
Toxicology Inc., Gainesville, FL, 2 Department of
Physiological Sciences, University of FL College of
Veterinary Medicine, Gainesville, FL, 3 S.C. Johnson &
Son, Inc., University of FL College of Veterinary
Medicine, Racine, WI, 4 Department of Statistics,
University of FL College of Veterinary Medicine,
Gainesville, FL and 5 University of FL College of
Medicine, Gainesville, FL.
#371 USE OF GENOMICS DATA TO PREDICT MODE
OF ACTION IN CHEMICAL HAZARD
CHARACTERIZATION. I. Pagan 1 and B. Sen 2,3 .
1 NCEA/ORD, U.S. EPA, Research Triangle Park, NC,
2 National Research Council, Washington, DC and
3 ECD/ORD, U.S. EPA, Research Triangle Park, NC.
#372 ASSIGNING OCCUPATIONAL HAZARD
CATEGORIES (OHCS) FOR MATERIALS USED
AND SYNTHESIZED IN THE
PHARMACEUTICAL INDUSTRY. F. J. Guerriero 1 ,
C. W. Seaman 2 , M. J. Olson 3 , M. W. Abromovitz 1 and
G. L. Sprague 1 . 1 GlaxoSmithKline, King of Prussia, PA,
2 GlaxoSmithKline, Ware, Herts, United Kingdom and
3 GlaxoSmithKline, Research Triangle Park, NC.
#373 USING STRUCTURE-ACTIVITY
RELATIONSHIPS FOR CHEMICAL HAZARD
SCREENING UNDER THE SUSTAINABLE
FUTURES PROGRAM. L. T. Haber 1 , A. Maier 1 , E.
Becker 2 and J. Santory 3 . 1 Toxicology Excellence for
Risk Assessment (TERA), Cincinnati, OH, 2 Consortium
for Environmental Risk Management (CERM),
Evansville, IN and 3 CERM, Pittsburgh, PA.
#374 SCIENTIFIC CRITERIA TO TEST INGREDIENTS
ADDED TO CIGARETTES. D. M. Byrd, A.
Brownawell, M. Falk, R. Feldman, K. Lewis and P.
Nixon. LSRO, Bethesda, MD.
#375 AN INTEGRATED DECISION TOOL FOR
EVALUATING CHEMICAL SAFETY IN
LABORATORY RESEARCH STUDIES
INVOLVING ANIMALS. A. Maier 1 , J. Utrecht 2 , C.
Pittinger 4 , J. Stewart 3 and A. Parker 1 . 1 Toxicology
Excellence for Risk Assessment (TERA), Cincinnati,
OH, 2 University of Cincinnati, Cincinnati, OH,
3 Environmental Health and Engineering, Newton, MA
and 4 Exponent, Inc., Cincinnati, OH.
#376 REAL WORLD TOXICOLOGY: A FRAMEWORK
FOR EVALUATING TORT CLAIMS IN THE
COURTROOM. S. M. Bobst 1 , N. Zheng 2 and F.
Thomas 2 . 1 CERATOX, Houston, TX and 2 RAM Group
Inc., Houston, TX. Sponsor: J. Jabbour.
#377 A FRAMEWORK/APPROACH FOR
INCORPORATING PBPK MODELING INTO
CUMULATIVE RISK ASSESSMENT OF
CHEMICAL MIXTURES. R. S. Yang 1 , J. E.
Dennison 1 and J. C. Lipscomb 2 . 1 Quantitative and
Computational Toxicology Group, Center for
Environmental Toxicology and Technology, Colorado
State University, Fort Collins, CO and 2 U.S. EPA,
ORD/NCEA, Cincinnati, OH.
#378 DEVELOPMENT OF A CHILDREN’S HEALTH
RISK ASSESSMENT FRAMEWORK USING A
LIFE-STAGE APPROACH. S. Barone 1 , R. Brown 2,1 ,
S. Euling 1 , E. Cohen-Hubal 3 , C. A. Kimmel 1 , S.
Makris 1 , J. Moya 1 , S. G. Selevan 1 , B. Sonawane 1 , T.
Thomas 4,1 and C. M. Thompson 4,1 . 1 NCEA, U.S. EPA,
Washington, DC, 2 ASPH, Association of Schools of
Public Health, Washington, DC, 3 NERL, U.S. EPA,
Research Triangle park, NC and 4 AAAS, American
Association for Advancement Science, Washington, DC.
#379 CASE STUDIES: DEVELOPING A DECISION-
MAKING FRAMEWORK FOR OCCUPATIONAL
HEALTH AND SAFETY CLEARANCE OF NEW
CHEMICALS. S. Kim 1 , A. Maier 2 , P. J. Hakkinen 2,3 ,
A. Wullenweber 2 , D. A. Seid 1 and L. T. Haber 2 .
1 2 Applied Biosystems, Foster City, CA, Toxicology
Excellence for Risk Assessment, Cincinnati, OH and
3 Institute for Health and Consumer Protection, Physical
and Chemical Exposure Unit, European Commission,
Joint Research Centre, Ispra, Italy.
#380 A RETROSPECTIVE REVIEW OF STUDIES
UTILIZING GAVAGE DOSING OF PRE-
WEANING RATS DEMONSTRATES NO
ADVERSE CONSEQUENCES OF DOSING
PROCEDURES. S. L. Makris 1 , E. Mendez 2 and K. C.
Raffaele 3 . 1 ORD/NCEA, U.S. EPA, Washington, DC,
2 3 OPP, U.S. EPA, Washington, DC and OPP, U.S. EPA,
Washington, DC.
#381 RISK ASSESSMENT IN NEPHROTOXICOLOGY
– SENSITIVITY OF RENAL TESTS. P. A. Potnis 1 ,
A. Maier 1 and T. L. Guidotti 1 . 1 Environmental and
Occupational Health, The George Washington
University, Washington, DC, 2 Toxicology, Toxicology
Excellence for Risk Assessment (TERA), Cincinnati,
OH and 3 Environmental and Occupational Health, The
George Washington University, Washington, DC.
#382 RELEVANCE OF RODENT FORESTOMACH
TUMORS IN CANCER RISK ASSESSMENT. D.
Proctor and S. Hong. Exponent, Irvine, CA.
#383 APPLICATION OF QSTRS TO SELECT A
SURROGATE CHEMICAL FOR A CHEMICAL
LACKING ORAL TOXICITY DATA. R. M. Bruce 1 ,
R. Venkatapathy 2 , C. Moudgal 1 and H. Choudhury 1 .
1 2 NCEA, U.S. EPA, Cincinnati, OH and ORISE/NCEA-
U.S. EPA, Cincinnati, OH.
#384 A HISTORICAL PERSPECTIVE ON LONG-
TERM ANIMAL BIOASSAYS. T. A. Lewandowski 1 ,
B. D. Beck 2 , L. A. Beyer 2 and L. R. Rhomberg 2 .
1 Gradient Corporation, Seattle, WA and
2 Gradient
Corporation, Cambridge, MA.
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SOT’s 44 th Annual Meeting