Program - Society of Toxicology

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44 th Annual Meeting and ToxExpo Program Description TUESDAY #1276 IDENTIFICATION OF A NOVEL VARIANT OF THE PREGNANE X RECEPTOR IN HEPATIC ADVERSE DRUG REACTION PATIENTS. J. D. Tugwood 1 , D. F. Carr 2 and H. Pringle 2 . 1 Safety Assessment, AstraZeneca Pharmaceuticals, Macclesfield, United Kingdom and 2 University of Leicester, Leicester, United Kingdom. Sponsor: F. Pognan. Tuesday Afternoon, March 8 1:30 PM to 4:30 PM Exhibit Hall POSTER SESSION: BIOMONITORING Chairperson(s): Steven Myers, University of Louisville, Louisville, KY and Xiaofei Zhang, UC Riverside, Riverside, CA. Displayed: 1:30 PM–4:30 PM Attended: 3:00 PM–4:30 PM #1277 MEASURING CHOLINESTERASE ACTIVITY IN HUMAN SALIVA. B. Claus Henn 1,2,3 , S. Padilla 2 and S. McMaster 3 . 1 ASPH Research Fellow, Research Triangle Park, NC, 2 NTD, U.S. EPA, Research Triangle Park, NC and 3 HSD, U.S. EPA, Research Triangle Park, NC. #1278 A CONVERSION FACTOR BETWEEN TWO CHOLINESTERASE ASSAYS AND ITS APPLICATION IN ESTABLISHING A NORMAL RANGE FOR HUMAN RBC ACHE. D. E. Arrieta 1 , V. M. Nihart 1 , J. D. Henderson 1 , S. A. McCurdy 2 , L. J. Lefkowitz 3 and B. W. Wilson 1 . 1 Environmental Toxicology and Animal Science, University of California, Davis, CA, 2 Epidemiology and Preventive Medicine, University of California, Davis, CA and 3 US Army Center for Health Promotion and Preventive Medicine, Aberdeen Proving Ground, MD. #1279 PESTICIDE EXPOSURE ASSESSMENT: CONCURRENT PASSIVE DOSIMETRY AND BIOLOGICAL MONITORING OF TRICLOPYR AND 2, 4-D EXPOSURES OF A BACKPACK APPLICATOR CREW. X. Zhang 1,2 , S. P. Acevedo 1 , Y. Chao 1 , T. M. Dinoff 1 , R. L. Williams 1,2 and R. I. Krieger 1,2 . 1 Personal Chemical Expsosure Program, Department of Entomology, University of California, Riverside, CA and 2 Environmental Toxicology Graduate Program, University of California, Riverside, CA. #1280 ENVIRONMENTAL INDUCTION OF CYP1A-, CYP2M1- AND CYP2K1-LIKE PROTEINS IN TROPICAL FISH SPECIES BY PRODUCED FORMATION WATER ON THE NORTHWEST SHELF OF AUSTRALIA. S. Zhu 1 , S. CodiKing 2 and M. L. Haasch 1 . 1 Pharmacology, Environmental Toxicology Research Program, NCNPR, University of Mississippi, University, MS and 2 Australian Institute of Marine Science, Townsville, QLD, Australia. #1281 ANALYSIS OF ENVIRONMENTAL POLLUTANTS IN BREAST MILK AND DNA DAMAGE IN BREAST-MILK CELLS. K. F. Arcaro 1,2 , J. W. Staudenmayer 3 , A. P. DeCaprio 3 , J. Wang 1 and M. T. Reece 3 . 1 Environmental Sciences, Univeristy of Massachusetts, Amherst, MA, 2 Veterinary & Animal Sciences, University of Massachusetts, Amherst, MA and 3 University of Massachusetts, Amherst, MA. #1282 AMBIENT AND BIOLOGICAL MONITORING OF EXPOSURE TO AROMATIC AMINES IN THE RUBBER INDUSTRY. T. Weiss 1,2 , H. U. Kaefferlein 2 , T. Bruening 2 and J. Angerer 1 . 1 Institute of Occupational Medicine, Friedrich-Alexander University, Erlangen, Germany and 2 Institute of Occupational Medicine–Center of Toxicology, Ruhr-University, Bochum, Germany. #1283 SINGLE NUCLEOTIDE POLYMORPHISM AT EXON 4 IN THE MICROSOMAL EPOXIDE HYDROLASE GENE IS ASSOCIATED WITH INCREASED AFLATOXIN ALBUMIN ADDUCTS IN THE BLOOD OF HUMANS IN GHANA. B. Dash 1 , E. Afriyie-Gyawu 1 , H. J. Huebner 1 , J. Wang 2 , P. E. Jolly 3 and T. D. Phillips 1 . 1 Faculty of Toxicology, Texas A&M University, College Station, TX, 2 Texas Tech University, Lubbock, TX and 3 University of Alabama, Birmingham, AL. #1284 CORRELATION OF MATERNAL HEMOGLOBIN (HB) 4-AMINOBIPHENYL ADDUCT LEVELS WITH RESPECT TO COTININE LEVELS AND MATERNAL GENOTYPES. S. R. Myers, C. Cunningham and T. Wright. Pharmacology and Toxicology, Center for Environmental and Occupational Health Sciences, University of Louisville, Louisville, KY. #1285 CORRELATION OF MATERNAL AND FETAL HEMOGLOBIN (HB) ADDUCTS IN SMOKERS WITH RESPECT TO GENOTYPE. C. Cunningham, T. Wright and S. R. Myers. Pharmacology and Toxicology, Center for Environmental and Occupational Health Sciences, University of Louisville, Louisville, KY. #1286 LEVELS OF POLYCYCLIC AROMATIC HYDROCARBONS IN AMNIOTIC FLUID SAMPLES FROM SMOKERS AND NONSMOKERS. J. Weeks and S. R. Myers. Pharmacology and Toxicology, Center for Environmental and Occupational Health Sciences, University of Louisville, Louisville, KY. #1287 INVESTIGATIONS OF VARIATION IN URINARY PROFILES BETWEEN SMOKERS AND NON- SMOKERS USING METABONOMIC (NMR SPECTROSCOPIC) URINALYSIS. M. Ogden. R&D, R. J. Reynolds, Winston-Salem, NC. Sponsor: D. Doolittle. 146 SOT’s 44 th Annual Meeting
44 th Annual Meeting and ToxExpo Program Description #1288 RACE/ETHNICITY, INCOME AND PERCHLOROETHYLENE (PERC) EXPOSURES AMONG ADULT AND CHILD RESIDENTS OF BUILDINGS WITH DRY CLEANERS. J. E. Storm 1 , M. J. McDermott 1 , K. M. Aldous 1 , B. C. Blount 2 , J. Serle 3 and S. J. Shost 1 . 1 Department of Health, New York State, Troy, NY, 2 US Centers for Disease Control and Prevention, Atlanta, GA and 3 Mt. Sinai School of Medicine, New York. #1289 HEALTH EVALUATION OF MARINE FISHES FROM JOHNSTON ATOLL NATIONAL WILDLIFE REFUGE, A FORMER MILITARY INSTALLATION. D. M. Papoulias 1 , J. L. Zajicek 1 , M. L. Annis 1 , D. K. Nicks 1 , J. S. Candrl 1 , L. Woodward 2 and D. E. Tillitt 1 . 1 USGS, Columbia Environmental Research Center, Columbia, MO and 2 USFWS, Honolulu, HI. Sponsor: C. Richter. #1290 EXPOSURE ASSESSMENT IN CONTAMINATED ENVIRONMENTS. R. A. Lingenfelter 1 , L. Cizmas 1 , Z. Naufal 1 , C. Naspinski 1 , L. He 1 , G. Zhou 1 , T. McDonald 1 , G. Denoux 1 , R. Autenrieth 1 , A. Mekhtiev 3 , A. Islamzadeh 2 and K. Donnelly 1 . 1 Texas A&M University, College Station, TX, 2 Institute of Physiology n.a. A.I.Karaev, Baku, Azerbaijan and 3 Sumgayit Centre For Environmental Rehabilitation, Sumgayit, Azerbaijan. #1291 INTEGRATION OF BIOMONITORING DATA INTO THE RISK ASSESSMENT PROCESS. S. H. Robison 1 , L. Needham 2 , E. Faustman 3 , H. Zenick 4 and L. Sheldon 5 . 1 Procter & Gamble, Cincinnati, OH, 2 CDC, Atlanta, GA, 3 University of Washington, Seattle, WA, 4 NHEERL, U.S. EPA, Research Triangle Park, NC and 5 NERL, U.S. EPA, Research Triangle Park, NC. Tuesday Afternoon, March 8 1:30 PM to 4:30 PM Exhibit Hall POSTER SESSION: STATISTICAL AND BIOLOGICAL MODELS Chairperson(s): Julia Kimbell, CIIT Centers for Health Research, Research Triangle Park, NC and Michael Zager, University of North Carolina, Research Triangle Park, NC. Displayed: 1:30 PM–4:30 PM Attended: 1:30 PM–3:00 PM #1292 A FLEXIBLE APPROACH FOR EVALUATING FIXED RATIO MIXTURES OF FULL AND PARTIAL AGONISTS FOR MIXTURES OF MANY CHEMICALS. C. Gennings 1,2 , H. Carter 1,2 , R. A. Carchman 2 , M. J. DeVito 3 , J. Simmons 3 and K. M. Crofton 3 . 1 Biostatistics, Virginia Commonwealth University, Richmond, VA, 2 Solveritas, LLC, Richmond, VA and 3 NHEERL, ORD, U.S. EPA, Research Triangle Park, NC. #1293 A BAYESIAN NETWORK MODEL TO PREDICT HAZARD POTENCY FOR SKIN SENSITISATION. D. Jefferies, L. J. Aspinall, R. J. Safford, C. J. Clapp, A. Madrigal, M. Chamberlain and D. A. Basketter. Safety and Environmental Assurance Centre, Unilever, Bedford, United Kingdom. #1294 TOXICITY-RELATED MOLECULAR PARAMETERS CALCULATED FOR ALDEHYDES AND KETONES FOUND IN DIESEL EXHAUST. P. Martin 1 , R. Garg 2 , M. C. Madden 3 and C. J. Smith 1 . 1 Lorillard Tobacco Co., Greensboro, NC, 2 Chemistry, Clarkson University, Potsdam, NY and 3 U.S. EPA NHEERL, Research Triangle Park, NC. #1295 THREE-DIMENSIONAL ANATOMICAL RECONSTRUCTION OF THE UPPER RESPIRATORY TRACT OF B6C3F1 MICE. E. A. Gross 1 , D. R. Joyner 1 , A. M. Jarabek 1,2 and J. S. Kimbell 1 . 1 CIIT Centers for Health Research, Research Triangle Park, NC and 2 National Center for Environmental Assessment, U.S. EPA, Washington, DC. #1296 A PHARMACOKINETIC-PHARMACODYNAMIC MODEL FOR GENE-REGULATED PROSTATE MAINTENANCE: COMPARING THE EFFECTS OF CASTRATION WITH ANTIANDROGEN EXPOSURE IN THE RAT. M. G. Zager 1,2 , L. K. Potter 1,2 and H. A. Barton 2 . 1 Toxicology, University of North Carolina, Research Triangle Park, NC and 2 ORD, NHEERL, U.S. EPA, Research Triangle Park, NC. #1297 PHYSIOLOGICALLY BASED PHARMACOKINETIC/PHARMACODYNAMIC MODELING FOR THE N-METHYL CARBAMATE PESTICIDE CARBARYL: INSIGHT INTO MECHANISM AND RISK ASSESSMENT. J. Wang 1 , Y. Tan 1 , A. Tobia 2 , C. Lunchick 2 , M. Krolski 2 and R. B. Conolly 1 . 1 CIIT Centers for Health Research, Research Triangle Park, NC and 2 Bayer CropScience, Research Triangle Park, NC. #1298 USE OF EXPOSURE RELATED DOSE ESTIMATING MODEL (ERDEM) FOR ASSESSMENT OF AGGREGATE EXPOSURE OF INFANTS AND CHILDREN TO N-METHYL CARBAMATE INSECTICIDES. F. W. Power 1 , M. Okino 1 , J. B. Knaak 4 , R. Tornero-Velez 2 , A. Lowit 3 , J. N. Blancato 2 and C. C. Dary 1 . 1 NERL\EDRB, U.S. EPA, Las Vegas, NV, 2 NERL, U.S. EPA, Research Triangle Park, NC, 3 Office of Pesticide Programs, U.S. EPA, Washington, DC and 4 Pharmacology and Toxicology, SUNY, Buffalo, Buffalo, NY. #1299 SPATIAL/TEMPORAL MODELING OF CYTOCHROME P450-MEDIATED PHOSPHOROTHIONATE INSECTICIDE METABOLISM IN THE RAT LIVER ACINUS. J. E. Chambers 1 , J. G. Baravik 1 , S. C. Burgess 1 , D. E. MaryBeth 1 , E. C. Meek 1 , S. F. Oppenheimer 2 and E. B. Shows 1 . 1 Center for Environmental Health Sciences, Mississippi State University, Mississippi State, MS and 2 Department of Mathematics and Statistics, Mississippi State University, Mississippi State, MS. #1300 BIOTRANS: A NEW TOOL FOR PREDICTING THE METABOLISM OF CHEMICAL MIXTURES. A. N. Mayeno, R. S. Yang and B. Reisfeld. Quantitative and Computational Toxicology Group, Center for Environmental Toxicology and Technology, Colorado State University, Fort Collins, CO. TUESDAY up-to-date information at www.toxicology.org 147
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Contents Program Overview .........
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Annual Meeting Events Calendar (Con
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Sheraton Hotel Map 44 th Annual Mee
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Itinerary Planner Computer Stations
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2005 Exhibitors (Continued) 44 th A
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General Information 44 th Annual Me
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2005 Award Winners The Society of T
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2004 Student Award Winners Colgate-
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INTERNATIONAL HARMONIZATION OF TECH
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Saturday Afternoon, March 5 2:00 PM
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SOT Affiliates for 2005 44 th Annua
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Headquarters Staff 44 th Annual Mee
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Program - Society of Toxicology

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