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Program - Society of Toxicology

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44 th Annual Meeting<br />

and ToxExpo<br />

<strong>Program</strong> Description<br />

Tuesday Afternoon, March 8<br />

12:00 NOON to 1:00 PM<br />

La Louisiane Ballroom B<br />

SOT/EUROTOX DEBATE<br />

Motion: Nanoparticles are a Major Threat to Human Health<br />

Sponsored by:<br />

SOT (<strong>Society</strong> <strong>of</strong> <strong>Toxicology</strong>)<br />

EUROTOX (European Societies <strong>of</strong> <strong>Toxicology</strong>)<br />

Debaters:<br />

(Pro) SOT: Joseph V. Rodricks, Ph.D., DABT, The ENVIRON<br />

Institute for Health Risk Sciences, Arlington, VA<br />

(Con) EUROTOX: Anthony Seaton, Pr<strong>of</strong> Emeritus, University <strong>of</strong><br />

Aberdeen, Scotland.<br />

Nanoparticles represent an explosively expanding technology for selective drug<br />

delivery. The number <strong>of</strong> potential applications is limitless; However the highly<br />

penetrant properties raises serious concern regarding wide-spread, uncontrolled<br />

distribution and possible persistence <strong>of</strong> these particles within living systems.<br />

The discussants will produce strong and persuasive arguments both in support<br />

and to refute adverse human health concerns <strong>of</strong> this rapidly emerging technology.<br />

Tuesday Afternoon, March 8<br />

12:15 PM to 1:15 PM<br />

Room 223<br />

INFORMATIONAL SESSION: RAPID GENERATION OF<br />

PREDICTIVE TOXICOGENOMIC ANALYSIS — PRESENTED BY<br />

GENE LOGIC<br />

Learn how to facilitate drug candidate selection by characterizing a compound's<br />

toxicity pr<strong>of</strong>ile using an easy, intuitive toxicogenomic-based s<strong>of</strong>tware application.<br />

Several case studies will be discussed that demonstrate how these rapidly<br />

generated results can be combined with other data to help make better inform<br />

compound decisions.<br />

Tuesday Afternoon, March 8<br />

1:30 PM to 2:30 PM<br />

Room 215<br />

INFORMATIONAL SESSION: LEVERAGING A MULTI-<br />

DIMENSIONAL CARDIOVASCULAR ASSESSMENT DURING LEAD<br />

OPTIMIZATION — PRESENTED BY CORDYNAMICS<br />

CorDynamics is a contract research organization focused on examining the<br />

cardiac effects <strong>of</strong> emerging drug candidates. Our models allow us to optimize<br />

these lead candidates early in the drug development process. Focusing on this<br />

critical and dynamic phase improves the attrition rates <strong>of</strong> compounds selected<br />

for further testing, thereby reducing the overall costs and timelines associated<br />

with your projects.<br />

Tuesday Afternoon, March 8<br />

1:30 PM to 3:30 PM<br />

Room RO2<br />

FORUM ON GRANTSMANSHIP AND SOURCES FOR RESEARCH<br />

SUPPORT<br />

Chairperson(s): Mitzi Nagarkatti, Virginia Commonwealth University,<br />

Richmond, VA and Rosita R. Proteau, Oregon State University, Corvallis, OR.<br />

Sponsored by:<br />

Career Resource and Development Committee (formerly the Placement<br />

Committee)<br />

Education Committee<br />

The Grantsmanship Forum will provide an overview <strong>of</strong> a variety <strong>of</strong> research<br />

funding sources and tips for successful applications for scientists at all stages <strong>of</strong><br />

their research careers.<br />

The first two talks will address NIH funding, including the reorganization <strong>of</strong> the<br />

review process by the Center for Scientific Research (CSR), which reviews the<br />

majority <strong>of</strong> applications to NIH. For the toxicology community, this restructuring<br />

has meant the elimination <strong>of</strong> two <strong>of</strong> the study sections in which many<br />

toxicology grant applications were reviewed. A third study section, used for<br />

neurotoxicology applications, was replaced. There has been confusion among<br />

applicants about the appropriate study section for their applications, as well as<br />

concern about toxicology applications getting proper reviews. The first speaker<br />

will provide a brief overview <strong>of</strong> the restructuring process, some results<br />

regarding toxicology applications from the first several review cycles, and some<br />

thoughts for applicants on how to work within the new system and hopefully be<br />

more successful.<br />

The second presentation will provide an overview <strong>of</strong> some <strong>of</strong> the specialized<br />

NIH grant mechanisms available to support research, training and career development.<br />

Included will be information on Career Development Awards (K series<br />

grants), Fellowships (F series grants), Training (T series grants), and research<br />

grants designed for specialized goals (R series grants).<br />

The EPA is another significant funding source for toxicologists. The third<br />

speaker will discuss EPA’S extramural grants and fellowship program with<br />

particular emphasis on Science to Achieve Results (STAR) <strong>Program</strong>. The EPA<br />

issues requests for applications in targeted areas that complement EPA’s intramural<br />

research programs. First, applications undergo a scientific review by an<br />

external peer panel, and then an internal programmatic review. These grants lead<br />

to interactions between extramural and intramural scientists. In addition, EPA<br />

supports graduate students in environmental science and engineering through<br />

the STAR program.<br />

Significant opportunities for research funding beyond NIH and EPA are also<br />

available. An experienced SOT investigator will provide perspectives on finding<br />

these sources. Learn ways to identify these alternative funding sources and their<br />

missions. Each funding source has a set <strong>of</strong> goals that need careful consideration<br />

as you apply for dollars to support your research effort.<br />

Time will be available for specific questions to these speakers.<br />

1:30 PM Introduction, Mitzi Nagarkatti, Virginia<br />

Commonwealth University, Richmond, VA.<br />

1:35 PM Reorganization <strong>of</strong> NIH Study Sections, Patrick<br />

Mastin, NIEHS, Research Triangle Park, NC.<br />

2:10 PM Non-Conventional Sources <strong>of</strong> NIH Funding, Carol<br />

Shreffler, NIEHS, Research Triangle Park, NC.<br />

2:45 PM Funding from Environmental Protection Agency,<br />

Elaine Z. Francis, U.S. EPA, Washington, DC.<br />

TUESDAY<br />

up-to-date information at www.toxicology.org 125

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