Program - Society of Toxicology

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44 th Annual Meeting and ToxExpo Program Description THURSDAY #2236 MODULATION OF NNK-INDUCED GENETIC DAMAGE BY POLYMORPHISM IN THE BASE EXCISION REPAIR GENE APE1 IN SMOKERS. K. Wolfe, A. A. Affatato, C. E. Hill, J. K. Wickliffe and S. Z. Abdel-Rahman. University of Texas Medical Branch, Galveston, TX. Thursday Morning, March 10 8:30 AM to 11:30 AM La Louisiane Ballroom B POSTER SESSION: DEVELOPMENTAL TOXICOLOGY MECHANISMS Chairperson(s): Asok Dasmahapatra, University of Mississippi, University, MS and Mary Haasch, University of Mississippi, University, MS. Displayed: 8:30 AM–11:30 AM Attended: 8:30 AM-10:00 AM #2237 THE MECHANISMS OF DITHIOCARBAMATE DEVELOPMENTAL TOXICITY. F. Tilton 1,2,3 and R. L. Tanguay 1,2,3 . 1 Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, 2 Marine & Freshwater Biomedical Sciences Center, Oregon State University, Corvallis, OR and 3 Environmental Health Sciences Center, Oregon State University, Corvallis, OR. #2238 TCDD ALTERS GENE EXPRESSION IN ZEBRAFISH OVARY: INSIGHT INTO THE MECHANISMS BY WHICH TCDD IMPACTS REPRODUCTION IN FISH. T. King Heiden 1,2 , M. Rise 1 , M. Hessner 3 , R. Hutz 1,2 and M. J. Carvan 1 . 1 UW- Milwaukee Great Lakes WATER Inst, Milwaukee, WI, 2 Biological Sciences, UW-Milwaukee, Milwaukee, WI and 3 Pediatrics, Medical College of Wisconsin, Milwaukee, WI. #2239 MATRIX METALLOPROTEINASE INHIBITION DURING ZEBRAFISH EMBRYOGENESIS FOLLOWING EXPOSURE TO HYDROCORTISONE AND DEXAMETHASONE. J. M. Hillegass, C. M. Villano, L. A. White and K. R. Cooper. Biochemistry & Microbiology, Rutgers, The State University of New Jersey, New Brunswick, NJ. #2240 EARLY EMBRYONIC RESPONSES OF ZEBRAFISH TO DIESEL PARTICULATE MATTER. M. D. Smith, S. J. D’Surney, V. Tillis, E. Johnson and E. Eiland. Biology, University of Mississippi, University, MS. #2241 ARYL HYDROCARBON RECEPTOR (AHR) ACTIVATION INHIBITS ZEBRAFISH EARLY LIFE STAGE CAUDAL FIN REGENERATION. L. K. Mathew, E. A. Andreasen and R. L. Tanguay. Environmental and Molecular Toxicology, The Environmental Health Sciences Center, and The Marine and Freshwater Biomedical Sciences Center, Oregon State University, Corvallis, OR. #2242 TCDD IMPAIRS EXTRACELLULAR MATRIX REMODELING IN THE REGENERATING ZEBRAFISH CAUDAL FIN. E. A. Andreasen, J. M. Zodrow, L. K. Mathew, R. Hasson and R. L. Tanguay. Environmental and Molecular Toxicology The Environmental Health Sciences Center, and The Marine Freshwater Biomedical Sciences Center, Oregon State University, Corvallis, OR. #2243 ETHANOL- AND ACETALDEHYDE-MEDIATED DEVELOPMENTAL TOXICITY IN ZEBRAFISH. M. Reimers, J. La Du, A. Flockton and R. Tanguay. Department of Environmental and Molecular Toxicology, The Environmental Health Sciences Center, and The Marine/Freshwater Biomedical Sciences Center, Oregon State University, Corvallis, OR. #2244 EFFECTS OF ETOPOSIDE ON HUMAN FETAL HEMATOPOIETIC STEM CELLS. C. G. Moneypenny, P. L. Stapleton and E. P. Gallagher. Environmental and Occupational Health Sciences, University of Washington, Seattle, WA. #2245 DOSE-DEPENDENT SURVIVAL DIFFERENCES IN CHICKENS DEVELOPMENTALLY CO- EXPOSED TO NEAR-INFRARED LIGHT THERAPY AND DIOXIN. R. L. Yeager 1 , J. A. Franzosa 1 , D. S. Millsap 1 , J. T. Eells 2 , H. T. Whelan 3 and D. S. Henshel 1 . 1 School of Public and Environmental Affairs, Indiana University, Bloomington, IN, 2 Department of Health Science, University of Wisconsin-Milwaukee, Milwaukee, WI and 3 Department of Neurology, Medical College of Wisconsin, Milwaukee, WI. #2246 ALTERATION OF NORMAL CARDIAC DEVELOPMENT BY TRICHLOROETHYLENE AND ITS METABOLITE TRICHLOROACETIC ACID. V. J. Drake 1 , S. L. Koprowski 2 , J. W. Lough 2 and S. M. Smith 1 . 1 Nutritional Sciences, University of Wisconsin-Madison, Madison, WI and 2 Cell Biology, Anatomy and Neurobiology, Medical College of Wisconsin, Milwaukee, WI. Sponsor: R. Hines. #2247 TOXICOGENOMICS IN MALFORMATIONS INDUCED BY FUNGICIDE FLUCONAZOLE. C. L. Galli 1 , E. Menegola 2 , E. Giavini 2 , E. Corsini 1 and M. Marinovich 1 . 1 Department.Pharmacological Sciences, University of Milan, Milan, Italy and 2 Department of Biology, University of Milan, Milan, Italy. #2248 RELATIVE POTENCIES OF SELECTED DIHALOACETIC ACIDS AND THEIR MAJOR METABOLITES IN MOUSE WHOLE EMBRYO CULTURE. S. Hunter, M. Blanton and E. Rogers. RTD, NHEERL, ORD, U.S. EPA, Research Triangle Park, NC. Sponsor: J. Rogers. #2249 EVALUATION OF GLYCOLIC ACID IN RABBIT WHOLE EMBRYO CULTURE. E. W. Carney, B. Tornesi and N. Moore. Toxicology & Environmental Research and Consulting, The Dow Chemical Company, Midland, MI. 220 SOT’s 44 th Annual Meeting
44 th Annual Meeting and ToxExpo Program Description #2250 ENDOGENOUS EMBRYONIC CATALASE ACTIVITY DURING ORGANOGENESIS IN EMBRYO CULTURE, IN VIVO AND AFTER EXPOSURE TO PHENYTOIN-ENHANCED OXIDATIVE STRESS. J. Perstin 1 and P. G. Wells 1,2 . 1 Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada and 2 Department of Pharmacology, University of Toronto, Toronto, ON, Canada. #2251 IN VITRO STUDY ON THE EMBRYOTOXIC POTENTIAL OF N-METHYL-PYRROLIDONE (NMP) AND ITS METABOLITES. B. Flick 1 , R. Jaeckh 2 and S. Klug 1 . 1 Institute of Clinical Pharmacology and Toxicology, Berlin, Germany and 2 BASF AG, Ludwigshafen, Germany. Sponsor: J. Sherman. #2252 IN VITRO STUDY ON THE EMBRYOTOXIC POTENTIAL OF BRANCHED-CHAIN CARBOXYLIC ACIDS. B. Flick 1 , R. Jaeckh 2 and S. Klug 1 . 1 Institute of Clinical Pharmacolgoy and Toxicology, Berlin, Germany and 2 BASF AG, Ludwigshafen, Germany. Sponsor: J. Sherman. #2253 CHARACTERIZATION OF ALCOHOL METABOLIZING ENZYMES IN JAPANESE MEDAKA. X. Wang 2,1 , E. S. Williams 2,1 , M. L. Haasch 1,2 and A. K. Dasmahapatra 1,2 . 1 Environmental Toxicology Research Program, NCNPR, RIPS, University of Mississippi, University, MS and 2 Department of Pharmacology, University of Mississippi, University, MS. #2254 VISUALIZATION OF TISSUE DISTRIBUTION AND METABOLISM OF BENZO(A)PYRENE IN EMBRYONIC MEDAKA (ORYZIAS LATIPES). M. W. Hornung, R. D. Johnson, P. M. Cook and J. W. Nichols. NHEERL, MED, U.S. EPA, Duluth, MN. #2255 PFOA INDUCES DYSMORPHOGENESIS IN MOUSE WHOLE EMBRYO CULTURE. M. R. Blanton 1 , J. M. Padowski 2 , S. S. Hunter 1 , J. M. Rogers 1 and C. Lau 1 . 1 RTD, NHEERL, ORD, U.S. EPA, Research Triangle Park, NC and 2 Curriculum in Toxicology, UNC, Chapel Hill, NC. #2256 THALIDOMIDE DEPLETES GLUTATHIONE AND INITIATES OXIDATIVE STRESS IN RAT NEURAL CREST CELLS. C. Harris and P. A. Paximadis. Environmental Health Sciences, University of Michigan, Ann Arbor, MI. #2257 EXAMINATION OF METAL-INDUCED CELL CYCLE ALTERATIONS AND APOPTOSIS IN C57BL/6 AND SWV MOUSE EMBRYONIC FIBROBLASTS. J. F. Robinson, X. Yu, J. S. Sidhu, S. Hong, E. Kim and E. M. Faustman. Environmental and Occupational Health Sciences, University of Washington, Seattle, WA. #2258 IDENTIFICATION OF GENE CLUSTERS AND SIGNALLING PATHWAYS AFFECTED BY DIBUTYL PHTHALATE–NUCLEAR RECEPTOR INTERACTIONS IN FOETAL RAT TESTES. S. Plummer 1 , N. Hallmark 2 , R. Sharpe 2 and C. Elcombe 1 . 1 CXR Biosciences Ltd., Dundee, United Kingdom and 2 MRC Human Reproductive Sciences Unit, Edinburgh, United Kingdom. #2259 VALPROIC ACID INCREASES CONSERVATIVE HOMOLOGOUS RECOMBINATION FREQUENCY: IMPLICATIONS FOR A MECHANISM OF VALPROIC ACID-INDUCED NEURAL TUBE DEFECTS. E. Defoort 1 , P. M. Kim 1 and L. M. Winn 1,2 . 1 Pharmacology and Toxicology, Queen’s University, Kingston, ON, Canada and 2 School of Environmental Studies, Queen’s University, Kingston, ON, Canada. #2260 TERATOGENIC EFFECTS OF FORSKOLIN, CYCLOPAMINE AND ETHANOL ON EARLY BRAIN AND EYE DEVELOPMENT. E. Loucks and S. Ahlgren. Childrens Memorial Research Center, Chicago, IL. #2261 PROTECTION AGAINST MNU-INDUCED FETAL MALFORMATIONS AND PLACENTAL MALDEVELOPMENT WITH DIETARY BUTYLATED HYDROXYTOLUENE SUPPLEMENTATION. M. R. Prater 1,2 , L. Pinn 2 , J. Keay 2 and S. D. Holladay 2 . 1 Biomedical Sciences, Edward Via Virginia College of Osteopathic Medicine, Blacksburg, VA and 2 Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA. Thursday Morning, March 10 8:30 AM to 11:30 AM La Louisiane Ballroom B POSTER SESSION: DNA AND PROTEIN ADDUCTS Chairperson(s): Scott W. Burchiel, University of New Mexico, Albuquerque, NM and Judy L. Bolton, University of Illinois, Chicago, IL. Displayed: 8:30 AM–11:30 AM Attended: 10:00 AM-11:30 AM #2262 N1- AND N7-DEOXYGUANOSINE ADDUCTS OF DIEPOXYBUTANE EXHIBIT DIFFERENT STABILITIES AND DECOMPOSITION PATTERNS UNDER PHYSIOLOGICAL CONDITIONS. X. Zhang and A. A. Elfarra. Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI. #2263 DEPURINATION OF NUCLEOSIDES INDUCED BY HALOGENATED ALKANES IN THE PHYSIOLOGICAL CONDITION. J. Kim, J. Sherchan, B. Arjun, B. Choi, E. Kim, Y. Jahng, T. Jeong and E. Lee. College of Pharmacy, Yeungnam University, Kyongsan, Kyongbuk, South Korea. #2264 EXPOSURE-BASED SAFETY ASSESSMENT OF THE NATURALLY OCCURRING FLAVOURING METHYL EUGENOL. J. Ellis 1 , P. L. Carmichael 2,1 and N. J. Gooderham 1 . 1 Biological Chemistry, Imperial College London, London, United Kingdom and 2 SEAC–Safety and Environmental Assurance, Unilever, Sharnbrook, United Kingdom. THURSDAY up-to-date information at www.toxicology.org 221
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Contents Program Overview .........
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Annual Meeting Events Calendar (Con
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2005 Award Winners The Society of T
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INTERNATIONAL HARMONIZATION OF TECH
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Saturday Afternoon, March 5 2:00 PM
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Program - Society of Toxicology

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