Program - Society of Toxicology

44 th Annual Meeting
and ToxExpo
Program Description
TUESDAY
#1152 ROLE OF PLASMA GLUTATHIONE IN HEPATIC
TOXICITY CAUSED BY VANADIUM
COMPOUNDS IN MICE. T. Hasegawa 1 , M. Satoh 2
and Y. Seko 1 . 1 Environmental Biochemistry, Yamanashi
Institute of Environmental Sciences, Fujiyoshida,
Yamanashi, Japan and 2 Department of Hygienics, Gifu
Pharmaceutical University, Gifu, Japan.
#1153 SPLEEN REPERCUSSIONS AFTER CHRONIC
INHALATION OF VANADIUM PENTOXIDE
(V2O5) EVALUATED IN MICE. T. I. FORTOUL 1 , G.
Pinon-Zarate 1 , A. Gonzalez-Villalva 1 , V. Rodriguez-
Lara 1 , M. Rojas-Lemus 1 , P. Mussali-Galante 1 , M. Avila-
Casado 1 , V. Delgado 1 , F. Pasos 1 , B. Chavez 1 and M.
AVILA-COSTA 2 . 1 Biologia Celular Y Tisular, Facultad
de Medicina, UNAM, Mexico, Mexico and
2 Neuromorfologia, Fes Iztacala, UNAM, Mexico,
Mexico.
#1154 ROLE OF OXIDATIVE STRESS IN THE
MODULATION OF AHR-REGULATED GENE
EXPRESSION BY HEAVY METALS. R. H. Elbekai
and A. O. El-Kadi. University of Alberta, Edmonton,
AB, Canada.
#1155 INTEGRATIVE ANALYSIS OF GENOME-WIDE
GENE EXPRESSION AND PATHWAY MAPPING
IN MOUSE EMBRYONIC FIBROBLAST (MEF)
EXPOSED TO CADMIUM, ARSENIC AND
METHYLMERCURY: INDUCTION OF
OXIDATIVE STRESS, DISRUPTION OF
UBIQUITIN-PROTEASOME SYSTEM AND CELL
CYCLE REGULATION. X. Yu, J. S. Sidhu, J. F.
Robinson, S. Hong and E. M. Faustman. Environmental
Health, IRARC, UW, Seattle, WA.
#1156 EFFECT OF COMBINED LEAD, CADMIUM AND
ARSENIC EXPOSURE ON THE EXPRESSION OF
CELLULAR PROTECTIVE FACTORS IN RAT
KIDNEYS AT LOEL DOSE LEVELS. G. Wang, X.
Chen, M. M. Lipsky, M. H. Whittaker and B. A. Fowler.
Toxicology Program, University of Maryland,
Baltimore, MD.
#1157 COMPARISON OF METALS IN CYTOTOXICITY,
FREE RADICAL GENERATION, AND HEAT
SHOCK PROTEIN EXPRESSION IN A HUMAN
BRONCHIAL EPITHELIAL CELL LINE, BEAS-
2B. S. Han 1,2 and V. Vallyathan 1 . 1 Pathology and
Physiology Research Branch, National Institute for
Occupational Safety and Health, Morgantown, WV and
2 Genetics and Developmental Biology, West Virginia
University, Morgantown, WV.
#1158 METAL-INDUCED OXIDATION OF
THIOREDOXIN-1 AND THIOREDOXIN-2. J. M.
Hansen and D. P. Jones. Medicine, Emory University,
Atlanta, GA.
#1159 INDUCTION OF OXIDATIVE STRESS IN
RESPONSE TO INGESTION OF LEAD,
CADMIUM AND ARSENIC MIXTURES. M. H.
Whittaker, B. A. Fowler, G. Wang, C. Xue-Qing and M.
Lipsky. Toxicology Program, The University of
Maryland, Baltimore, Baltimore, MD.
#1160 CHANGING METAL ACCUMULATION IN NEW
ORLEANS: DIFFERENCES BETWEEN SURVEY
I (1992) AND SURVEY II (2000). H. W. Mielke 1 , E.
Powell 1 , C. Gonzales 1 and P. Mielke (Emeritus) 2 .
1 College of Pharmacy, Xavier University, New Orleans,
LA and 2 Statistics, Colorado State University, Fort
Collins, CO.
Tuesday Afternoon, March 8
1:30 PM to 4:30 PM
Exhibit Hall
POSTER SESSION: GENE REGULATION: METALS
Chairperson(s): Jay Gandolfi, University of Arizona, Tucson, AZ.
Displayed: 1:30 PM–4:30 PM
Attended: 1:30 PM–3:00 PM
#1161 TOXICOGENOMICAL STUDY ON HUMAN
BLADDER EPITHELIUM EXPOSED TO
ARSENIC. X. Zheng 1 , T. G. Bredfeldt 1 , G. S. Watts 2
and A. Gandolfi 1 . 1 Pharmacology/Toxicology, College
of Pharmacy, University of Arizona, Tucson, AZ and
2 Arizona Cancer Center, University of Arizona, Tucson,
AZ.
#1162 DIFFERENTIAL EFFECTS OF CHRONIC LOW
LEVEL ARSENIC EXPOSURES ON
TRANSCRIPTION FACTOR BINDING IN
CARDIOVASCULAR TISSUES. L. R. Klei 1,2 , M. A.
Ihnat 3 , N. V. Soucy 2 , A. A. Nemec 1 and A.
Barchowsky 1,2 . 1 Environmental and Occupational
Health, University of Pittsburgh Graduate School of
Public Health, Pittsburgh, PA, 2 Pharmacology and
Toxicology, Dartmouth Medical School, Hanover, NH
and 3 Cell Biology, University of Oklahoma Health
Sciences Center, Oklahoma City, OK.
#1163 EUKARYOTIC TRANSLATION INITIATION
FACTOR 4E IS A CELLULAR TARGET FOR
ARSENIC BUT NOT CHROMIUM TOXICITY. P.
Joseph and S. Othumpangat. NIOSH, Morgantown,
WV.
#1164 EFFECT OF ARSENITE ON PU.1, C/EBPS, AND
NFKB ACTIVATION IN U937 PROMONOCYTIC
LEUKEMIA CELLS. M. Yamamoto 1 , S. Hirano 1 , C.
R. Jefcoate 2 and F. Matsumura 3 . 1 Environmental Health
Sciences Division, National Institute for Environmental
Studies, Tsukuba, Ibaraki, Japan, 2 Pharmacology,
University of Wisconsin-Madison, Madison, WI and
3 Environmental Toxicology, University of California-
Davis, Davis, CA.
#1165 IDENTIFICATION OF MOUSE SLC39A8 AS THE
TRANSPORTER RESPONSIBLE FOR
CADMIUM-INDUCED TOXICITY IN THE
TESTIS. L. He 1 , T. P. Dalton 1 , B. Wang 1 , M. L. Miller 1 ,
L. Jin 1 , K. F. Stringer 2 , X. Chang 1 , C. S. Baxter 1 and D.
W. Nebert 1 . 1 Department of Environmental Health, and
the Center for Environmental Genetics (CEG),
University of Cincinnati, Cincinnati, OH and
2 Department of Pathology, Cincinnati Children’s
Hospital Medical Center, Cincinnati, OH.
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SOT’s 44 th Annual Meeting